NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|118776270|gb|ABL14188|]
View 

NifH, partial [Burkholderia vietnamiensis]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
NifH/CfbC super family cl43394
Nitrogenase ATPase subunit NifH/coenzyme F430 biosynthesis subunit CfbC [Coenzyme transport ...
 1-190 6.48e-127

Nitrogenase ATPase subunit NifH/coenzyme F430 biosynthesis subunit CfbC [Coenzyme transport and metabolism, Inorganic ion transport and metabolism];


The actual alignment was detected with superfamily member COG1348:

Pssm-ID: 440959  Cd Length: 276  Bit Score: 357.94  E-value: 6.48e-127
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270   1 AALTDLGQKILIVGCDPKADSTRLILHAKAQDTILSLAAEAGsvEDLELEDVMKIGYKDIRCVESGGPEPGVGCAGRGVI 80
Cdd:COG1348   24 AALAEMGKKVMQIGCDPKADSTRLLLGGKRIPTVLDTLREKG--EDVELEDIVFEGFGGVKCVEAGGPEPGVGCAGRGII 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270  81 TSINFLEENGAYD-GVDYVSYDVLGDVVCGGFAMPIRENKAQEIYIVMSGEMMAMYAANNISKGILKYANSGGVRLGGLV 159
Cdd:COG1348  102 TAIELLEELGAYEeDLDVVIYDVLGDVVCGGFAMPIREGYADEIYIVTSGEFMALYAANNICKGIKKYANRGGVRLGGII 181

                        170       180       190
                 ....*....|....*....|....*....|.
gi 118776270 160 CNERQTDKELELAEALAGMLGTRLIHFVPRD 190
Cdd:COG1348  182 CNSRNVDGERELVEEFAERLGTQIIAFVPRS 212
 
Name Accession Description Interval E-value
NifH/CfbC COG1348
Nitrogenase ATPase subunit NifH/coenzyme F430 biosynthesis subunit CfbC [Coenzyme transport ...
 1-190 6.48e-127

Nitrogenase ATPase subunit NifH/coenzyme F430 biosynthesis subunit CfbC [Coenzyme transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440959  Cd Length: 276  Bit Score: 357.94  E-value: 6.48e-127
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270   1 AALTDLGQKILIVGCDPKADSTRLILHAKAQDTILSLAAEAGsvEDLELEDVMKIGYKDIRCVESGGPEPGVGCAGRGVI 80
Cdd:COG1348   24 AALAEMGKKVMQIGCDPKADSTRLLLGGKRIPTVLDTLREKG--EDVELEDIVFEGFGGVKCVEAGGPEPGVGCAGRGII 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270  81 TSINFLEENGAYD-GVDYVSYDVLGDVVCGGFAMPIRENKAQEIYIVMSGEMMAMYAANNISKGILKYANSGGVRLGGLV 159
Cdd:COG1348  102 TAIELLEELGAYEeDLDVVIYDVLGDVVCGGFAMPIREGYADEIYIVTSGEFMALYAANNICKGIKKYANRGGVRLGGII 181

                        170       180       190
                 ....*....|....*....|....*....|.
gi 118776270 160 CNERQTDKELELAEALAGMLGTRLIHFVPRD 190
Cdd:COG1348  182 CNSRNVDGERELVEEFAERLGTQIIAFVPRS 212
nifH TIGR01287
nitrogenase iron protein; This model describes nitrogenase (EC 1.18.6.1) iron protein, also ...
 1-190 9.70e-125

nitrogenase iron protein; This model describes nitrogenase (EC 1.18.6.1) iron protein, also called nitrogenase reductase or nitrogenase component II. This model includes molybdenum-iron nitrogenase reductase (nifH), vanadium-iron nitrogenase reductase (vnfH), and iron-iron nitrogenase reductase (anfH). The model excludes the homologous protein from the light-independent protochlorophyllide reductase. [Central intermediary metabolism, Nitrogen fixation]


Pssm-ID: 273538  Cd Length: 275  Bit Score: 352.46  E-value: 9.70e-125
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270    1 AALTDLGQKILIVGCDPKADSTRLILHAKAQDTILSLAAEAGSvEDLELEDVMKIGYKDIRCVESGGPEPGVGCAGRGVI 80
Cdd:TIGR01287  22 AALAEMGKKVMIVGCDPKADSTRLLLGGKAQPTVLDVLREKGA-EDLELEDVIKEGFGGIRCVESGGPEPGVGCAGRGVI 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270   81 TSINFLEENGAY-DGVDYVSYDVLGDVVCGGFAMPIRENKAQEIYIVMSGEMMAMYAANNISKGILKYANSGGVRLGGLV 159
Cdd:TIGR01287 101 TAINLLEELGAYeDDLDFVFYDVLGDVVCGGFAMPIREGKAQEIYIVTSGEMMALYAANNICKGILKYAKSGGVRLGGLI 180

                         170       180       190
                  ....*....|....*....|....*....|.
gi 118776270  160 CNERQTDKELELAEALAGMLGTRLIHFVPRD 190
Cdd:TIGR01287 181 CNSRNVDDEKELIDEFAKKLGTQLIHFVPRS 211
NifH cd02040
nitrogenase component II NifH; NifH gene encodes component II (iron protein) of nitrogenase. ...
 1-190 2.17e-117

nitrogenase component II NifH; NifH gene encodes component II (iron protein) of nitrogenase. Nitrogenase is responsible for the biological nitrogen fixation, i.e. reduction of molecular nitrogen to ammonia. NifH consists of two oxygen-sensitive metallosulfur proteins: the mollybdenum-iron (alternatively, vanadium-iron or iron-iron) protein (commonly referred to as component 1), and the iron protein (commonly referred to as component 2). The iron protein is a homodimer, with an Fe4S4 cluster bound between the subunits and two ATP-binding domains. It supplies energy by ATP hydrolysis, and transfers electrons from reduced ferredoxin or flavodoxin to component 1 for the reduction of molecular nitrogen to ammonia.


Pssm-ID: 349759  Cd Length: 265  Bit Score: 333.33  E-value: 2.17e-117
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270   1 AALTDLGQKILIVGCDPKADSTRLILHAKAQDTILSLAAEAGsvEDLELEDVMKIGYKDIRCVESGGPEPGVGCAGRGVI 80
Cdd:cd02040   22 AALAEMGKKVLHVGCDPKADSTRLLLGGKAIPTVLDTLREKG--EVEELEDVIKEGFNGIKCVESGGPEPGVGCAGRGII 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270  81 TSINFLEENGAYD-GVDYVSYDVLGDVVCGGFAMPIRENKAQEIYIVMSGEMMAMYAANNISKGILKYANSGGVRLGGLV 159
Cdd:cd02040  100 TAINLLEELGAYEeDLDVVFYDVLGDVVCGGFAMPIREGYADEVYIVTSGEMMALYAANNIAKGIVKYAERGGVRLGGLI 179

                        170       180       190
                 ....*....|....*....|....*....|.
gi 118776270 160 CNERQTDKELELAEALAGMLGTRLIHFVPRD 190
Cdd:cd02040  180 CNSRNVDREEELVEEFAERLGTQIIHFVPRS 210
Fer4_NifH pfam00142
4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family;
1-190 2.85e-111

4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family;


Pssm-ID: 395090  Cd Length: 271  Bit Score: 318.23  E-value: 2.85e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270    1 AALTDLGQKILIVGCDPKADSTRLILHAKAQDTILSLAAEAGSVEDLELEDVMKIGYKDIRCVESGGPEPGVGCAGRGVI 80
Cdd:pfam00142  22 AALAEMGKKVLVVGCDPKADSTRLLLGGKLQPTVLDTAREKGYVEDVEVEDVVYKGYGGVKCVESGGPEPGVGCAGRGVI 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270   81 TSINFLEENGAYDGVDYVSYDVLGDVVCGGFAMPIRENKAQEIYIVMSGEMMAMYAANNISKGILKYANSGGVRLGGLVC 160
Cdd:pfam00142 102 TAINLLEELGAYDDLDFVLYDVLGDVVCGGFAMPIREGKAQEIYIVTSNEMMALYAANNIAKGIQKYAKSGGVRLGGIIC 181

                         170       180       190
                  ....*....|....*....|....*....|
gi 118776270  161 NERQTDKELELAEALAGMLGTRLIHFVPRD 190
Cdd:pfam00142 182 NSRKVDDERELIDAFAEELGTQVLHFVPRD 211
nifH PRK13233
nitrogenase iron protein;
7-190 8.69e-99

nitrogenase iron protein;


Pssm-ID: 183905  Cd Length: 275  Bit Score: 286.72  E-value: 8.69e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270   7 GQKILIVGCDPKADSTRLILHAKAQDTILSLAAEAGSvEDLELEDVMKIGYKDIRCVESGGPEPGVGCAGRGVITSINFL 86
Cdd:PRK13233  31 DKKVFIHGCDPKADSTRLILGGKPQTTMMDTLRELGE-EKVTPDKVIKTGFKDIRCVESGGPEPGVGCAGRGVITAIDLM 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270  87 EENGAY-DGVDYVSYDVLGDVVCGGFAMPIRENKAQEIYIVMSGEMMAMYAANNISKGILKYANSGGVRLGGLVCNERQT 165
Cdd:PRK13233 110 EENGAYtDDLDFVFFDVLGDVVCGGFAMPIRDGKAQEVYIVASGEMMAIYAANNICKGLVKYAEQSGVRLGGIICNSRNV 189

                        170       180
                 ....*....|....*....|....*
gi 118776270 166 DKELELAEALAGMLGTRLIHFVPRD 190
Cdd:PRK13233 190 DGELELLEEFTDAIGTQMIHFVPRD 214
F430_CfbC NF033200
Ni-sirohydrochlorin a,c-diamide reductive cyclase ATP-dependent reductase subunit; This family, ...
 1-190 2.70e-87

Ni-sirohydrochlorin a,c-diamide reductive cyclase ATP-dependent reductase subunit; This family, very closely related to the nitrogenase iron protein, was identified as a subunit involved in biosynthesis of coenzyme F430 in archaeal methanogens and archaeal anaerobic methanotrophs.


Pssm-ID: 380202  Cd Length: 260  Bit Score: 257.11  E-value: 2.70e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270   1 AALTDLGQKILIVGCDPKADSTRLILHAKAQDTILSLAAEAGsveDLELEDVMKIGYKDIRCVESGGPEPGVGCAGRGVI 80
Cdd:NF033200  22 AALSEEGKKVMVIGCDPKADSTRTLMGGRRIPTILDLLRENK---NIKEEDVVFEGYGGVRCVESGGPEPGVGCAGRGII 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270  81 TSINFLEENGAYDG-VDYVSYDVLGDVVCGGFAMPIRENKAQEIYIVMSGEMMAMYAANNISKGILKYANsggvRLGGLV 159
Cdd:NF033200  99 VAMQLLEKLGAFMEdLDVIIYDVLGDVVCGGFAVPLREGYADEVYIVTSGEYMSLYAANNICKGIKKLKG----RLGGII 174

                        170       180       190
                 ....*....|....*....|....*....|.
gi 118776270 160 CNERQTDKELELAEALAGMLGTRLIHFVPRD 190
Cdd:NF033200 175 CNSRNIENEEEIVEEFAERIGSRLIGFIPRS 205
 
Name Accession Description Interval E-value
NifH/CfbC COG1348
Nitrogenase ATPase subunit NifH/coenzyme F430 biosynthesis subunit CfbC [Coenzyme transport ...
 1-190 6.48e-127

Nitrogenase ATPase subunit NifH/coenzyme F430 biosynthesis subunit CfbC [Coenzyme transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440959  Cd Length: 276  Bit Score: 357.94  E-value: 6.48e-127
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270   1 AALTDLGQKILIVGCDPKADSTRLILHAKAQDTILSLAAEAGsvEDLELEDVMKIGYKDIRCVESGGPEPGVGCAGRGVI 80
Cdd:COG1348   24 AALAEMGKKVMQIGCDPKADSTRLLLGGKRIPTVLDTLREKG--EDVELEDIVFEGFGGVKCVEAGGPEPGVGCAGRGII 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270  81 TSINFLEENGAYD-GVDYVSYDVLGDVVCGGFAMPIRENKAQEIYIVMSGEMMAMYAANNISKGILKYANSGGVRLGGLV 159
Cdd:COG1348  102 TAIELLEELGAYEeDLDVVIYDVLGDVVCGGFAMPIREGYADEIYIVTSGEFMALYAANNICKGIKKYANRGGVRLGGII 181

                        170       180       190
                 ....*....|....*....|....*....|.
gi 118776270 160 CNERQTDKELELAEALAGMLGTRLIHFVPRD 190
Cdd:COG1348  182 CNSRNVDGERELVEEFAERLGTQIIAFVPRS 212
nifH TIGR01287
nitrogenase iron protein; This model describes nitrogenase (EC 1.18.6.1) iron protein, also ...
 1-190 9.70e-125

nitrogenase iron protein; This model describes nitrogenase (EC 1.18.6.1) iron protein, also called nitrogenase reductase or nitrogenase component II. This model includes molybdenum-iron nitrogenase reductase (nifH), vanadium-iron nitrogenase reductase (vnfH), and iron-iron nitrogenase reductase (anfH). The model excludes the homologous protein from the light-independent protochlorophyllide reductase. [Central intermediary metabolism, Nitrogen fixation]


Pssm-ID: 273538  Cd Length: 275  Bit Score: 352.46  E-value: 9.70e-125
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270    1 AALTDLGQKILIVGCDPKADSTRLILHAKAQDTILSLAAEAGSvEDLELEDVMKIGYKDIRCVESGGPEPGVGCAGRGVI 80
Cdd:TIGR01287  22 AALAEMGKKVMIVGCDPKADSTRLLLGGKAQPTVLDVLREKGA-EDLELEDVIKEGFGGIRCVESGGPEPGVGCAGRGVI 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270   81 TSINFLEENGAY-DGVDYVSYDVLGDVVCGGFAMPIRENKAQEIYIVMSGEMMAMYAANNISKGILKYANSGGVRLGGLV 159
Cdd:TIGR01287 101 TAINLLEELGAYeDDLDFVFYDVLGDVVCGGFAMPIREGKAQEIYIVTSGEMMALYAANNICKGILKYAKSGGVRLGGLI 180

                         170       180       190
                  ....*....|....*....|....*....|.
gi 118776270  160 CNERQTDKELELAEALAGMLGTRLIHFVPRD 190
Cdd:TIGR01287 181 CNSRNVDDEKELIDEFAKKLGTQLIHFVPRS 211
NifH cd02040
nitrogenase component II NifH; NifH gene encodes component II (iron protein) of nitrogenase. ...
 1-190 2.17e-117

nitrogenase component II NifH; NifH gene encodes component II (iron protein) of nitrogenase. Nitrogenase is responsible for the biological nitrogen fixation, i.e. reduction of molecular nitrogen to ammonia. NifH consists of two oxygen-sensitive metallosulfur proteins: the mollybdenum-iron (alternatively, vanadium-iron or iron-iron) protein (commonly referred to as component 1), and the iron protein (commonly referred to as component 2). The iron protein is a homodimer, with an Fe4S4 cluster bound between the subunits and two ATP-binding domains. It supplies energy by ATP hydrolysis, and transfers electrons from reduced ferredoxin or flavodoxin to component 1 for the reduction of molecular nitrogen to ammonia.


Pssm-ID: 349759  Cd Length: 265  Bit Score: 333.33  E-value: 2.17e-117
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270   1 AALTDLGQKILIVGCDPKADSTRLILHAKAQDTILSLAAEAGsvEDLELEDVMKIGYKDIRCVESGGPEPGVGCAGRGVI 80
Cdd:cd02040   22 AALAEMGKKVLHVGCDPKADSTRLLLGGKAIPTVLDTLREKG--EVEELEDVIKEGFNGIKCVESGGPEPGVGCAGRGII 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270  81 TSINFLEENGAYD-GVDYVSYDVLGDVVCGGFAMPIRENKAQEIYIVMSGEMMAMYAANNISKGILKYANSGGVRLGGLV 159
Cdd:cd02040  100 TAINLLEELGAYEeDLDVVFYDVLGDVVCGGFAMPIREGYADEVYIVTSGEMMALYAANNIAKGIVKYAERGGVRLGGLI 179

                        170       180       190
                 ....*....|....*....|....*....|.
gi 118776270 160 CNERQTDKELELAEALAGMLGTRLIHFVPRD 190
Cdd:cd02040  180 CNSRNVDREEELVEEFAERLGTQIIHFVPRS 210
Fer4_NifH pfam00142
4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family;
1-190 2.85e-111

4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family;


Pssm-ID: 395090  Cd Length: 271  Bit Score: 318.23  E-value: 2.85e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270    1 AALTDLGQKILIVGCDPKADSTRLILHAKAQDTILSLAAEAGSVEDLELEDVMKIGYKDIRCVESGGPEPGVGCAGRGVI 80
Cdd:pfam00142  22 AALAEMGKKVLVVGCDPKADSTRLLLGGKLQPTVLDTAREKGYVEDVEVEDVVYKGYGGVKCVESGGPEPGVGCAGRGVI 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270   81 TSINFLEENGAYDGVDYVSYDVLGDVVCGGFAMPIRENKAQEIYIVMSGEMMAMYAANNISKGILKYANSGGVRLGGLVC 160
Cdd:pfam00142 102 TAINLLEELGAYDDLDFVLYDVLGDVVCGGFAMPIREGKAQEIYIVTSNEMMALYAANNIAKGIQKYAKSGGVRLGGIIC 181

                         170       180       190
                  ....*....|....*....|....*....|
gi 118776270  161 NERQTDKELELAEALAGMLGTRLIHFVPRD 190
Cdd:pfam00142 182 NSRKVDDERELIDAFAEELGTQVLHFVPRD 211
nifH PRK13233
nitrogenase iron protein;
7-190 8.69e-99

nitrogenase iron protein;


Pssm-ID: 183905  Cd Length: 275  Bit Score: 286.72  E-value: 8.69e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270   7 GQKILIVGCDPKADSTRLILHAKAQDTILSLAAEAGSvEDLELEDVMKIGYKDIRCVESGGPEPGVGCAGRGVITSINFL 86
Cdd:PRK13233  31 DKKVFIHGCDPKADSTRLILGGKPQTTMMDTLRELGE-EKVTPDKVIKTGFKDIRCVESGGPEPGVGCAGRGVITAIDLM 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270  87 EENGAY-DGVDYVSYDVLGDVVCGGFAMPIRENKAQEIYIVMSGEMMAMYAANNISKGILKYANSGGVRLGGLVCNERQT 165
Cdd:PRK13233 110 EENGAYtDDLDFVFFDVLGDVVCGGFAMPIRDGKAQEVYIVASGEMMAIYAANNICKGLVKYAEQSGVRLGGIICNSRNV 189

                        170       180
                 ....*....|....*....|....*
gi 118776270 166 DKELELAEALAGMLGTRLIHFVPRD 190
Cdd:PRK13233 190 DGELELLEEFTDAIGTQMIHFVPRD 214
F430_CfbC NF033200
Ni-sirohydrochlorin a,c-diamide reductive cyclase ATP-dependent reductase subunit; This family, ...
 1-190 2.70e-87

Ni-sirohydrochlorin a,c-diamide reductive cyclase ATP-dependent reductase subunit; This family, very closely related to the nitrogenase iron protein, was identified as a subunit involved in biosynthesis of coenzyme F430 in archaeal methanogens and archaeal anaerobic methanotrophs.


Pssm-ID: 380202  Cd Length: 260  Bit Score: 257.11  E-value: 2.70e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270   1 AALTDLGQKILIVGCDPKADSTRLILHAKAQDTILSLAAEAGsveDLELEDVMKIGYKDIRCVESGGPEPGVGCAGRGVI 80
Cdd:NF033200  22 AALSEEGKKVMVIGCDPKADSTRTLMGGRRIPTILDLLRENK---NIKEEDVVFEGYGGVRCVESGGPEPGVGCAGRGII 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270  81 TSINFLEENGAYDG-VDYVSYDVLGDVVCGGFAMPIRENKAQEIYIVMSGEMMAMYAANNISKGILKYANsggvRLGGLV 159
Cdd:NF033200  99 VAMQLLEKLGAFMEdLDVIIYDVLGDVVCGGFAVPLREGYADEVYIVTSGEYMSLYAANNICKGIKKLKG----RLGGII 174

                        170       180       190
                 ....*....|....*....|....*....|.
gi 118776270 160 CNERQTDKELELAEALAGMLGTRLIHFVPRD 190
Cdd:NF033200 175 CNSRNIENEEEIVEEFAERIGSRLIGFIPRS 205
NifH-like cd02117
NifH family; This family contains the NifH (iron protein) of nitrogenase, L subunit (BchL/ChlL) ...
 1-190 4.72e-83

NifH family; This family contains the NifH (iron protein) of nitrogenase, L subunit (BchL/ChlL) of the protochlorophyllide reductase, and the BchX subunit of the Chlorophyllide reductase. Members of this family use energy from ATP hydrolysis and transfer electrons through a Fe4-S4 cluster to other subunit for substrate reduction


Pssm-ID: 349761  Cd Length: 266  Bit Score: 246.51  E-value: 4.72e-83
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270   1 AALTDLGQKILIVGCDPKADSTRLILHAKAQDTILSLAAEAGSVEDLELEDVMKIGYKDIRCVESGGPEPGVGCAGRGVI 80
Cdd:cd02117   22 AALAEGGKKVLHVGCDPKHDSTLLLTGGKVPPTIDEMLTEDGTAEELRREDLLFSGFNGVDCVEAGGPEPGVGCGGRGIG 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270  81 TSINFLEENGAY-DGVDYVSYDVLGDVVCGGFAMPIRENKAQEIYIVMSGEMMAMYAANNISKGILKYANsGGVRLGGLV 159
Cdd:cd02117  102 TMLELLEEHGLLdDDYDVVIFDVLGDVVCGGFAAPLRRGFAQKVVIVVSEELMSLYAANNIVKAVENYSK-NGVRLAGLV 180

                        170       180       190
                 ....*....|....*....|....*....|.
gi 118776270 160 CNERQTDkELELAEALAGMLGTRLIHFVPRD 190
Cdd:cd02117  181 ANLRDPA-GTEEIQAFAAAVGTKILAVIPRD 210
PRK13230 PRK13230
nitrogenase reductase-like protein; Reviewed
 1-188 4.47e-68

nitrogenase reductase-like protein; Reviewed


Pssm-ID: 183903  Cd Length: 279  Bit Score: 208.86  E-value: 4.47e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270   1 AALTDLGQKILIVGCDPKADSTRLILHAKAqDTILSLAAEAGsVEDLELEDVMKIGYKDIRCVESGGPEPGVGCAGRGVI 80
Cdd:PRK13230  23 AALAESGKKVLVVGCDPKADCTRNLVGEKI-PTVLDVLREKG-IDNLGLEDIIYEGFNGIYCVESGGPEPGYGCAGRGVI 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270  81 TSINFLEENGAYD--GVDYVSYDVLGDVVCGGFAMPIRENKAQEIYIVMSGEMMAMYAANNISKGILKYANSGGVRLGGL 158
Cdd:PRK13230 101 TAIDLLKKLGVFEelGPDVVIYDILGDVVCGGFAMPLQKGLADDVYIVTTCDPMAIYAANNICKGIKRFAKRGKSALGGI 180

                        170       180       190
                 ....*....|....*....|....*....|
gi 118776270 159 VCNERQTDKELELAEALAGMLGTRLIHFVP 188
Cdd:PRK13230 181 IYNGRSVIDAPDIVEEFAKKIGTNVIGKIP 210
PRK13231 PRK13231
nitrogenase reductase-like protein; Reviewed
 1-189 2.83e-61

nitrogenase reductase-like protein; Reviewed


Pssm-ID: 183904  Cd Length: 264  Bit Score: 191.16  E-value: 2.83e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270   1 AALTDLGQKILIVGCDPKADSTRlILHAKAQDTILSLAAEAgsvEDLELEDVMKIGYKDIRCVESGGPEPGVGCAGRGVI 80
Cdd:PRK13231  23 AAAYSNDHRVLVIGCDPKADTTR-TLCGKRIPTVLDTLKDN---RKPELEDIIHEGFNGILCVESGGPEPGVGCAGRGVI 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270  81 TSINFLEENGAYDG-VDYVSYDVLGDVVCGGFAMPIRENKAQEIYIVMSGEMMAMYAANNISKGILKYANsggvRLGGLV 159
Cdd:PRK13231  99 VAMNLLENLGVFDEdIDVVIYDVLGDVVCGGFSVPLREDYADEVYIVTSGEYMSLYAANNIARGIKKLKG----KLGGII 174

                        170       180       190
                 ....*....|....*....|....*....|
gi 118776270 160 CNERQTDKELELAEALAGMLGTRLIHFVPR 189
Cdd:PRK13231 175 CNCRGIDNEVEIVSEFASRIGSRIIGVIPR 204
Bchl-like cd02032
L-subunit of protochlorophyllide reductase; This family of proteins contains BchL and ChlL. ...
 1-189 1.11e-41

L-subunit of protochlorophyllide reductase; This family of proteins contains BchL and ChlL. Protochlorophyllide reductase catalyzes the reductive formation of chlorophyllide from protochlorophyllide during biosynthesis of chlorophylls and bacteriochlorophylls. Three genes, bchL, bchN and bchB, are involved in light-independent protochlorophyllide reduction in bacteriochlorophyll biosynthesis. In cyanobacteria, algae, and gymnosperms, three similar genes, chlL, chlN and chlB are involved in protochlorophyllide reduction during chlorophylls biosynthesis. BchL/chlL, bchN/chlN and bchB/chlB exhibit significant sequence similarity to the nifH, nifD and nifK subunits of nitrogenase, respectively. Nitrogenase catalyzes the reductive formation of ammonia from dinitrogen.


Pssm-ID: 349752  Cd Length: 267  Bit Score: 140.90  E-value: 1.11e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270   1 AALTDLGQKILIVGCDPKADSTRLILHAKAQDTILSLAAEAGSVEDLELEDVMKIGYKDIRCVESGGPEPGVGCAGRGVI 80
Cdd:cd02032   22 AAFAKRGKKVLQIGCDPKHDSTFTLTGFLIPTVIDVLQSVDFHYEEVWPEDVIFTGYGGVDCVEAGGPPAGTGCGGYVVG 101

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270  81 TSINFLEENGAYDGVDYVSYDVLGDVVCGGFAMPIreNKAQEIYIVMSGEMMAMYAANNISKGILKYANSGGVRLGGLVC 160
Cdd:cd02032  102 ETVKLLKELNAFDEYDVILFDVLGDVVCGGFAAPL--NYADYCLIVTANDFDSLFAANRIAAAVREKAKTYPVRLAGIIG 179

                        170       180
                 ....*....|....*....|....*....
gi 118776270 161 NerQTDKeLELAEALAGMLGTRLIHFVPR 189
Cdd:cd02032  180 N--RTDK-TDLIDKFVEAVPMPVLEVLPL 205
chlL PRK13185
protochlorophyllide reductase iron-sulfur ATP-binding protein; Provisional
 1-189 3.91e-39

protochlorophyllide reductase iron-sulfur ATP-binding protein; Provisional


Pssm-ID: 237293  Cd Length: 270  Bit Score: 134.70  E-value: 3.91e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270   1 AALTDLGQKILIVGCDPKADSTrLILHAKAQDTILSLAAEAG-SVEDLELEDVMKIGYKDIRCVESGGPEPGVGCAGRGV 79
Cdd:PRK13185  24 AAFAKLGKKVLQIGCDPKHDST-FTLTGKLVPTVIDILEEVDfHSEELRPEDFVYEGYNGVDCVEAGGPPAGTGCGGYVV 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270  80 ITSINFLEENGAYDGVDYVSYDVLGDVVCGGFAMPIreNKAQEIYIVMSGEMMAMYAANNISKGILKYANSGGVRLGGLV 159
Cdd:PRK13185 103 GETVKLLKEHHLLDDYDVILFDVLGDVVCGGFAAPL--QYADYALIVTANDFDSIFAANRIAAAIQAKAKNYKVRLAGVI 180

                        170       180       190
                 ....*....|....*....|....*....|.
gi 118776270 160 CNE-RQTDKELELAEAlagmLGTRLIHFVPR 189
Cdd:PRK13185 181 ANRsAGTDLIDKFNEA----VGLKVLAHVPD 207
BchX cd02033
X-subunit of protochlorophyllide reductase; Chlorophyllide reductase converts chlorophylls ...
 7-190 2.24e-31

X-subunit of protochlorophyllide reductase; Chlorophyllide reductase converts chlorophylls into bacteriochlorophylls by reducing the chlorin B-ring. This family contains the X subunit of this three-subunit enzyme. Sequence and structure similarity between bchX, protochlorophyllide reductase L subunit (bchL and chlL) and nitrogenase Fe protein (nifH gene) suggest their functional similarity. Members of the BchX family serve as the unique electron donors to their respective catalytic subunits (bchN-bchB, bchY-bchZ and nitrogenase component 1). Mechanistically, they hydrolyze ATP and transfer electrons through a Fe4-S4 cluster.


Pssm-ID: 349753  Cd Length: 329  Bit Score: 115.70  E-value: 2.24e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270   7 GQKILIVGCDPKADSTRLILHAKAQDTILSLAAE---AGsvEDLELEDV-MKIGykDIRCVESGGPEPGVGCAGRGVITS 82
Cdd:cd02033   59 GKRVLLIGCDPKSDTTSLLFGGKACPTIIETSTRkklAG--EEVKIGDVcFKRG--GVFAMELGGPEVGRGCGGRGIIHG 134

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270  83 INFLEENGAYD-GVDYVSYDVLGDVVCGGFAMPIRENKAQEIYIVMSGEMMAMYAANNISKGILKYANSGG-VRLGGLVC 160
Cdd:cd02033  135 FELLEKLGFHDwGFDYVLLDFLGDVVCGGFGLPIARDMCQKVIVVGSNDLQSLYVANNVCSAVEYFRKLGGnVGVAGIVI 214

                        170       180       190
                 ....*....|....*....|....*....|
gi 118776270 161 NERQTDKElelAEALAGMLGTRLIHFVPRD 190
Cdd:cd02033  215 NKDDGTGE---AQAFAKAAGIPVLAAIPAD 241
chlL CHL00072
photochlorophyllide reductase subunit L
 2-169 7.42e-31

photochlorophyllide reductase subunit L


Pssm-ID: 177011  Cd Length: 290  Bit Score: 113.68  E-value: 7.42e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270   2 ALTDLGQKILIVGCDPKADSTRLILHAKAQDTILSLAAEAGSVEDLELEDVMKIGYKDIRCVESGGPEPGVGCAGRGVIT 81
Cdd:CHL00072  23 ALARRGKKVLQIGCDPKHDSTFTLTGFLIPTIIDTLQSKDYHYEDVWPEDVIYKGYGGVDCVEAGGPPAGAGCGGYVVGE 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 118776270  82 SINFLEENGAYDGVDYVSYDVLGDVVCGGFAMPIreNKAQEIYIVMSGEMMAMYAANNISKGILKYANSGGVRLGGLVCN 161
Cdd:CHL00072 103 TVKLLKELNAFYEYDIILFDVLGDVVCGGFAAPL--NYADYCIIITDNGFDALFAANRIAASVREKARTHPLRLAGLVGN 180


                 ....*...
gi 118776270 162 eRQTDKEL 169
Cdd:CHL00072 181 -RTSKRDL 187
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH