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Conserved domains on  [gi|430769177|gb|AGA63738|]
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recombinase A, partial [Lactiplantibacillus plantarum]

Protein Classification

DNA recombination/repair protein RecA( domain architecture ID 11484000)

DNA recombination/repair protein RecA catalyzes an ATP-dependent DNA strand-exchange reaction, which is a critical step in the repair of DNA double-strand breaks by homologous recombination

Gene Ontology:  GO:0005524|GO:0003697|GO:0006310|GO:0006281

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
recA PRK09354
recombinase A; Provisional
 1-242 0e+00

recombinase A; Provisional


:

Pssm-ID: 236476 [Multi-domain]  Cd Length: 349  Bit Score: 522.43  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177   1 ALKKIEKNFGKGAIMRMGDAAQTTISTISSGSLALDDALGVGGYPRGRIVEIYGPESSGKTTVALHAVAEVQKQGGTAAY 80
Cdd:PRK09354  14 ALKQIEKQFGKGSIMRLGDDAAMDVEVISTGSLALDIALGIGGLPRGRIVEIYGPESSGKTTLALHAIAEAQKAGGTAAF 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  81 IDAENALDPVYAEHLGVNIDDLLLSQPDTGEQGLEIADALVSSGAVDILVVDSVAALVPRAEIEGEMGDAHVGLQARLMS 160
Cdd:PRK09354  94 IDAEHALDPVYAKKLGVDIDNLLVSQPDTGEQALEIADTLVRSGAVDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLMS 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177 161 QALRKLSGTLNKTKTIALFINQIREKVGVMFGNPETTPGGRALKFYATIRLEVRRAEQIKEGTNIIGNRVRIKVVKNKVA 240
Cdd:PRK09354 174 QALRKLTGNISKSNTTVIFINQIREKIGVMFGNPETTTGGNALKFYASVRLDIRRIGTIKDGDEVIGNRTKVKVVKNKVA 253


                 ..
gi 430769177 241 PP 242
Cdd:PRK09354 254 PP 255
 
Name Accession Description Interval E-value
recA PRK09354
recombinase A; Provisional
 1-242 0e+00

recombinase A; Provisional


Pssm-ID: 236476 [Multi-domain]  Cd Length: 349  Bit Score: 522.43  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177   1 ALKKIEKNFGKGAIMRMGDAAQTTISTISSGSLALDDALGVGGYPRGRIVEIYGPESSGKTTVALHAVAEVQKQGGTAAY 80
Cdd:PRK09354  14 ALKQIEKQFGKGSIMRLGDDAAMDVEVISTGSLALDIALGIGGLPRGRIVEIYGPESSGKTTLALHAIAEAQKAGGTAAF 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  81 IDAENALDPVYAEHLGVNIDDLLLSQPDTGEQGLEIADALVSSGAVDILVVDSVAALVPRAEIEGEMGDAHVGLQARLMS 160
Cdd:PRK09354  94 IDAEHALDPVYAKKLGVDIDNLLVSQPDTGEQALEIADTLVRSGAVDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLMS 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177 161 QALRKLSGTLNKTKTIALFINQIREKVGVMFGNPETTPGGRALKFYATIRLEVRRAEQIKEGTNIIGNRVRIKVVKNKVA 240
Cdd:PRK09354 174 QALRKLTGNISKSNTTVIFINQIREKIGVMFGNPETTTGGNALKFYASVRLDIRRIGTIKDGDEVIGNRTKVKVVKNKVA 253


                 ..
gi 430769177 241 PP 242
Cdd:PRK09354 254 PP 255
RecA COG0468
RecA/RadA recombinase [Replication, recombination and repair];
1-242 0e+00

RecA/RadA recombinase [Replication, recombination and repair];


Pssm-ID: 440236 [Multi-domain]  Cd Length: 351  Bit Score: 513.18  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177   1 ALKKIEKNFGKGAIMRMGDAAQTTISTISSGSLALDDALGVGGYPRGRIVEIYGPESSGKTTVALHAVAEVQKQGGTAAY 80
Cdd:COG0468   17 ALSQIEKQFGKGSIMRLGDKARQDVEVISTGSLALDIALGVGGLPRGRIVEIYGPESSGKTTLALHAIAEAQKAGGIAAF 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  81 IDAENALDPVYAEHLGVNIDDLLLSQPDTGEQGLEIADALVSSGAVDILVVDSVAALVPRAEIEGEMGDAHVGLQARLMS 160
Cdd:COG0468   97 IDAEHALDPEYAKKLGVDIDNLLVSQPDTGEQALEIAETLVRSGAVDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLMS 176

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177 161 QALRKLSGTLNKTKTIALFINQIREKVGVMFGNPETTPGGRALKFYATIRLEVRRAEQIKEGTNIIGNRVRIKVVKNKVA 240
Cdd:COG0468  177 QALRKLTGAISKSNTTVIFINQLREKIGVMFGNPETTTGGNALKFYASVRLDIRRIGTIKDGDEVIGNRTRVKVVKNKVA 256


                 ..
gi 430769177 241 PP 242
Cdd:COG0468  257 PP 258
tigrfam_recA TIGR02012
protein RecA; This model describes orthologs of the recA protein. RecA promotes hybridization ...
 1-242 4.15e-167

protein RecA; This model describes orthologs of the recA protein. RecA promotes hybridization of homolgous regions of DNA. A segment of ssDNA can be hybridized to another ssDNA region, or to a dsDNA region. ATP is hydrolyzed in the process. Part of the SOS respones, it is regulated by LexA via autocatalytic cleavage. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 162659 [Multi-domain]  Cd Length: 321  Bit Score: 463.77  E-value: 4.15e-167
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177    1 ALKKIEKNFGKGAIMRMGDAAQTTISTISSGSLALDDALGVGGYPRGRIVEIYGPESSGKTTVALHAVAEVQKQGGTAAY 80
Cdd:TIGR02012   9 ALAQIEKQFGKGSIMRLGEKTVMDVETISTGSLALDLALGVGGLPKGRIIEIYGPESSGKTTLALHAIAEAQKAGGTAAF 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177   81 IDAENALDPVYAEHLGVNIDDLLLSQPDTGEQGLEIADALVSSGAVDILVVDSVAALVPRAEIEGEMGDAHVGLQARLMS 160
Cdd:TIGR02012  89 IDAEHALDPVYARKLGVDIDNLLVSQPDTGEQALEIAETLVRSGAVDIIVVDSVAALVPKAEIEGEMGDSHVGLQARLMS 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  161 QALRKLSGTLNKTKTIALFINQIREKVGVMFGNPETTPGGRALKFYATIRLEVRRAEQIKEGTNIIGNRVRIKVVKNKVA 240
Cdd:TIGR02012 169 QALRKLTGALSKSNTTAIFINQIREKIGVMFGNPETTTGGNALKFYASVRLDIRRIGTVKQGEEVVGNRTKVKVVKNKVA 248


                  ..
gi 430769177  241 PP 242
Cdd:TIGR02012 249 PP 250
RecA pfam00154
recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA ...
 1-242 2.96e-166

recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA repair systems. RecA protein catalyzes an ATP-dependent DNA strand-exchange reaction that is the central step in the repair of dsDNA breaks by homologous recombination.


Pssm-ID: 425488 [Multi-domain]  Cd Length: 262  Bit Score: 459.17  E-value: 2.96e-166
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177    1 ALKKIEKNFGKGAIMRMGDAAQTTISTISSGSLALDDALGVGGYPRGRIVEIYGPESSGKTTVALHAVAEVQKQGGTAAY 80
Cdd:pfam00154   6 ALKQIEKQFGKGSIMKLGDEKKLDVETISTGSLALDIALGIGGYPKGRIIEIYGPESSGKTTLALHAIAEAQKAGGTAAF 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177   81 IDAENALDPVYAEHLGVNIDDLLLSQPDTGEQGLEIADALVSSGAVDILVVDSVAALVPRAEIEGEMGDAHVGLQARLMS 160
Cdd:pfam00154  86 IDAEHALDPVYAKKLGVDIDNLLVSQPDTGEQALEIADMLVRSGAIDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLMS 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  161 QALRKLSGTLNKTKTIALFINQIREKVGVMFGNPETTPGGRALKFYATIRLEVRRAEQIKEGTNIIGNRVRIKVVKNKVA 240
Cdd:pfam00154 166 QALRKLTGSISKSNTTVIFINQIREKIGVMFGNPETTTGGRALKFYASVRLDIRRIGQIKQGEEVIGNKTKVKVVKNKVA 245


                  ..
gi 430769177  241 PP 242
Cdd:pfam00154 246 PP 247
RecA cd00983
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ...
 25-242 8.35e-159

recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange.


Pssm-ID: 410863 [Multi-domain]  Cd Length: 235  Bit Score: 439.30  E-value: 8.35e-159
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  25 ISTISSGSLALDDALGVGGYPRGRIVEIYGPESSGKTTVALHAVAEVQKQGGTAAYIDAENALDPVYAEHLGVNIDDLLL 104
Cdd:cd00983    2 VEVIPTGSLSLDIALGIGGLPRGRIIEIYGPESSGKTTLALHAIAEAQKLGGTAAFIDAEHALDPEYAKKLGVDIDNLLV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177 105 SQPDTGEQGLEIADALVSSGAVDILVVDSVAALVPRAEIEGEMGDAHVGLQARLMSQALRKLSGTLNKTKTIALFINQIR 184
Cdd:cd00983   82 SQPDTGEQALEIADTLIRSGAVDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKLTGSLSKSKTTVIFINQLR 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 430769177 185 EKVGVMFGNPETTPGGRALKFYATIRLEVRRAEQIKEGTNIIGNRVRIKVVKNKVAPP 242
Cdd:cd00983  162 EKIGVMFGNPETTTGGNALKFYASVRLDIRRIELIKEGEDVIGNRTKVKVVKNKVAPP 219
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 46-217 6.28e-10

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 56.23  E-value: 6.28e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177    46 RGRIVEIYGPESSGKTTVALHAVAEVQKQGGTAAYIDAENALDPVYAEHLGVNIDDLLLSqpDTGEQGLEIADALVSSGA 125
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKAS--GSGELRLRLALALARKLK 78

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177   126 VDILVVDSVAALVPRaeiegemgdahVGLQARLMSQALRKLSGTLNKTKTIALFINqirekvgvmfgNPETTPGGRALKF 205
Cdd:smart00382  79 PDVLILDEITSLLDA-----------EQEALLLLLEELRLLLLLKSEKNLTVILTT-----------NDEKDLGPALLRR 136

                          170
                   ....*....|..
gi 430769177   206 YATIRLEVRRAE 217
Cdd:smart00382 137 RFDRRIVLLLIL 148
 
Name Accession Description Interval E-value
recA PRK09354
recombinase A; Provisional
 1-242 0e+00

recombinase A; Provisional


Pssm-ID: 236476 [Multi-domain]  Cd Length: 349  Bit Score: 522.43  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177   1 ALKKIEKNFGKGAIMRMGDAAQTTISTISSGSLALDDALGVGGYPRGRIVEIYGPESSGKTTVALHAVAEVQKQGGTAAY 80
Cdd:PRK09354  14 ALKQIEKQFGKGSIMRLGDDAAMDVEVISTGSLALDIALGIGGLPRGRIVEIYGPESSGKTTLALHAIAEAQKAGGTAAF 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  81 IDAENALDPVYAEHLGVNIDDLLLSQPDTGEQGLEIADALVSSGAVDILVVDSVAALVPRAEIEGEMGDAHVGLQARLMS 160
Cdd:PRK09354  94 IDAEHALDPVYAKKLGVDIDNLLVSQPDTGEQALEIADTLVRSGAVDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLMS 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177 161 QALRKLSGTLNKTKTIALFINQIREKVGVMFGNPETTPGGRALKFYATIRLEVRRAEQIKEGTNIIGNRVRIKVVKNKVA 240
Cdd:PRK09354 174 QALRKLTGNISKSNTTVIFINQIREKIGVMFGNPETTTGGNALKFYASVRLDIRRIGTIKDGDEVIGNRTKVKVVKNKVA 253


                 ..
gi 430769177 241 PP 242
Cdd:PRK09354 254 PP 255
RecA COG0468
RecA/RadA recombinase [Replication, recombination and repair];
1-242 0e+00

RecA/RadA recombinase [Replication, recombination and repair];


Pssm-ID: 440236 [Multi-domain]  Cd Length: 351  Bit Score: 513.18  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177   1 ALKKIEKNFGKGAIMRMGDAAQTTISTISSGSLALDDALGVGGYPRGRIVEIYGPESSGKTTVALHAVAEVQKQGGTAAY 80
Cdd:COG0468   17 ALSQIEKQFGKGSIMRLGDKARQDVEVISTGSLALDIALGVGGLPRGRIVEIYGPESSGKTTLALHAIAEAQKAGGIAAF 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  81 IDAENALDPVYAEHLGVNIDDLLLSQPDTGEQGLEIADALVSSGAVDILVVDSVAALVPRAEIEGEMGDAHVGLQARLMS 160
Cdd:COG0468   97 IDAEHALDPEYAKKLGVDIDNLLVSQPDTGEQALEIAETLVRSGAVDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLMS 176

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177 161 QALRKLSGTLNKTKTIALFINQIREKVGVMFGNPETTPGGRALKFYATIRLEVRRAEQIKEGTNIIGNRVRIKVVKNKVA 240
Cdd:COG0468  177 QALRKLTGAISKSNTTVIFINQLREKIGVMFGNPETTTGGNALKFYASVRLDIRRIGTIKDGDEVIGNRTRVKVVKNKVA 256


                 ..
gi 430769177 241 PP 242
Cdd:COG0468  257 PP 258
tigrfam_recA TIGR02012
protein RecA; This model describes orthologs of the recA protein. RecA promotes hybridization ...
 1-242 4.15e-167

protein RecA; This model describes orthologs of the recA protein. RecA promotes hybridization of homolgous regions of DNA. A segment of ssDNA can be hybridized to another ssDNA region, or to a dsDNA region. ATP is hydrolyzed in the process. Part of the SOS respones, it is regulated by LexA via autocatalytic cleavage. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 162659 [Multi-domain]  Cd Length: 321  Bit Score: 463.77  E-value: 4.15e-167
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177    1 ALKKIEKNFGKGAIMRMGDAAQTTISTISSGSLALDDALGVGGYPRGRIVEIYGPESSGKTTVALHAVAEVQKQGGTAAY 80
Cdd:TIGR02012   9 ALAQIEKQFGKGSIMRLGEKTVMDVETISTGSLALDLALGVGGLPKGRIIEIYGPESSGKTTLALHAIAEAQKAGGTAAF 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177   81 IDAENALDPVYAEHLGVNIDDLLLSQPDTGEQGLEIADALVSSGAVDILVVDSVAALVPRAEIEGEMGDAHVGLQARLMS 160
Cdd:TIGR02012  89 IDAEHALDPVYARKLGVDIDNLLVSQPDTGEQALEIAETLVRSGAVDIIVVDSVAALVPKAEIEGEMGDSHVGLQARLMS 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  161 QALRKLSGTLNKTKTIALFINQIREKVGVMFGNPETTPGGRALKFYATIRLEVRRAEQIKEGTNIIGNRVRIKVVKNKVA 240
Cdd:TIGR02012 169 QALRKLTGALSKSNTTAIFINQIREKIGVMFGNPETTTGGNALKFYASVRLDIRRIGTVKQGEEVVGNRTKVKVVKNKVA 248


                  ..
gi 430769177  241 PP 242
Cdd:TIGR02012 249 PP 250
RecA pfam00154
recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA ...
 1-242 2.96e-166

recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA repair systems. RecA protein catalyzes an ATP-dependent DNA strand-exchange reaction that is the central step in the repair of dsDNA breaks by homologous recombination.


Pssm-ID: 425488 [Multi-domain]  Cd Length: 262  Bit Score: 459.17  E-value: 2.96e-166
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177    1 ALKKIEKNFGKGAIMRMGDAAQTTISTISSGSLALDDALGVGGYPRGRIVEIYGPESSGKTTVALHAVAEVQKQGGTAAY 80
Cdd:pfam00154   6 ALKQIEKQFGKGSIMKLGDEKKLDVETISTGSLALDIALGIGGYPKGRIIEIYGPESSGKTTLALHAIAEAQKAGGTAAF 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177   81 IDAENALDPVYAEHLGVNIDDLLLSQPDTGEQGLEIADALVSSGAVDILVVDSVAALVPRAEIEGEMGDAHVGLQARLMS 160
Cdd:pfam00154  86 IDAEHALDPVYAKKLGVDIDNLLVSQPDTGEQALEIADMLVRSGAIDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLMS 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  161 QALRKLSGTLNKTKTIALFINQIREKVGVMFGNPETTPGGRALKFYATIRLEVRRAEQIKEGTNIIGNRVRIKVVKNKVA 240
Cdd:pfam00154 166 QALRKLTGSISKSNTTVIFINQIREKIGVMFGNPETTTGGRALKFYASVRLDIRRIGQIKQGEEVIGNKTKVKVVKNKVA 245


                  ..
gi 430769177  241 PP 242
Cdd:pfam00154 246 PP 247
RecA cd00983
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ...
 25-242 8.35e-159

recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange.


Pssm-ID: 410863 [Multi-domain]  Cd Length: 235  Bit Score: 439.30  E-value: 8.35e-159
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  25 ISTISSGSLALDDALGVGGYPRGRIVEIYGPESSGKTTVALHAVAEVQKQGGTAAYIDAENALDPVYAEHLGVNIDDLLL 104
Cdd:cd00983    2 VEVIPTGSLSLDIALGIGGLPRGRIIEIYGPESSGKTTLALHAIAEAQKLGGTAAFIDAEHALDPEYAKKLGVDIDNLLV 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177 105 SQPDTGEQGLEIADALVSSGAVDILVVDSVAALVPRAEIEGEMGDAHVGLQARLMSQALRKLSGTLNKTKTIALFINQIR 184
Cdd:cd00983   82 SQPDTGEQALEIADTLIRSGAVDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKLTGSLSKSKTTVIFINQLR 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 430769177 185 EKVGVMFGNPETTPGGRALKFYATIRLEVRRAEQIKEGTNIIGNRVRIKVVKNKVAPP 242
Cdd:cd00983  162 EKIGVMFGNPETTTGGNALKFYASVRLDIRRIELIKEGEDVIGNRTKVKVVKNKVAPP 219
recA PRK09519
intein-containing recombinase RecA;
1-238 4.68e-123

intein-containing recombinase RecA;


Pssm-ID: 77219 [Multi-domain]  Cd Length: 790  Bit Score: 367.88  E-value: 4.68e-123
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177   1 ALKKIEKNFGKGAIMRMGDAAQTTISTISSGSLALDDALGVGGYPRGRIVEIYGPESSGKTTVALHAVAEVQKQGGTAAY 80
Cdd:PRK09519  14 AVAQIEKSYGKGSVMRLGDEARQPISVIPTGSIALDVALGIGGLPRGRVIEIYGPESSGKTTVALHAVANAQAAGGVAAF 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  81 IDAENALDPVYAEHLGVNIDDLLLSQPDTGEQGLEIADALVSSGAVDILVVDSVAALVPRAEIEGEMGDAHVGLQARLMS 160
Cdd:PRK09519  94 IDAEHALDPDYAKKLGVDTDSLLVSQPDTGEQALEIADMLIRSGALDIVVIDSVAALVPRAELEGEMGDSHVGLQARLMS 173

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 430769177 161 QALRKLSGTLNKTKTIALFINQIREKVGVMFGNPETTPGGRALKFYATIRLEVRRAEQIKEGTNIIGNRVRIKVVKNK 238
Cdd:PRK09519 174 QALRKMTGALNNSGTTAIFINQLRDKIGVMFGSPETTTGGKALKFYASVRMDVRRVETLKDGTNAVGNRTRVKVVKNK 251
RecA-like cd01393
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ...
 47-215 7.02e-48

RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange. While prokaryotes have a single RecA protein, eukaryotes have multiple RecA homologs such as Rad51, DMC1 and Rad55/57. Archaea have the RecA-like homologs RadA and RadB.


Pssm-ID: 410881 [Multi-domain]  Cd Length: 185  Bit Score: 156.36  E-value: 7.02e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  47 GRIVEIYGPESSGKTTVALHAVAEVQKQGGTAAYIDAENALDPVYA-----------EHLGVNIDDLLLSQPDTGEQGLE 115
Cdd:cd01393    1 GKITEIYGPPGSGKTQLALQLAANALLLGGGVVWIDTEGAFPPSRLvqileaspsseLELAEALSRLLYFRPPDTLAHLL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177 116 IADALV----SSGAVDILVVDSVAALVPRAEIEGEMGDAHVGLQARLMSQALRKLSGTLNKTKTIALFINQIREKVGVMF 191
Cdd:cd01393   81 ALDSLPeslfPPPNTSLVVVDSVSALFRKAFPRGGDGDSSSSLRARLLSQLARALQKLAAQFNLAVVVTNQVTTKIRGGS 160

                        170       180
                 ....*....|....*....|....*
gi 430769177 192 G-NPETTPGGRALKFYATIRLEVRR 215
Cdd:cd01393  161 GaSLVPPALGNTWEHSVSTRLLLYR 185
archRadB cd01394
archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional ...
 28-220 6.92e-21

archaeal RadB; The archaeal protein RadB shares similarity RadA, the archaeal functional homologue to the bacterial RecA. The precise function of RadB is unclear.


Pssm-ID: 410882 [Multi-domain]  Cd Length: 216  Bit Score: 87.37  E-value: 6.92e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  28 ISSGSLALDDALGvGGYPRGRIVEIYGPESSGKTTVALHAVAEVQKQGGTAAYIDAE----NALDPVYAEHLGVNIDDLL 103
Cdd:cd01394    1 LSTGSKSLDSLLG-GGVERGTITQIYGPPGSGKTNICLQLAVEAAKQGKKVVYIDTEglspERFQQIAGERFESIASNII 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177 104 LSQP-DTGEQGLEIADA--LVSSGAVDILVVDSVAALVpRAEiegEMGDAhvGLQARLMSQaLRKLSGTLNKTKTIALFI 180
Cdd:cd01394   80 VFEPySFDEQGVAIQEAekLLKSDKVDLVVVDSATALY-RLE---LGDDS--EANRELSRQ-MSKLLSIARKYDIPVVIT 152

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 430769177 181 NQIREKvgvmFGNPETTP-GGRALKFY--ATIRLE-----VRRAEQIK 220
Cdd:cd01394  153 NQVYSD----IDDDRLKPvGGTLLEHWskAIIRLEksppgLRRATLEK 196
recomb_radB TIGR02237
DNA repair and recombination protein RadB; This family consists exclusively of archaeal RadB ...
 35-235 1.74e-16

DNA repair and recombination protein RadB; This family consists exclusively of archaeal RadB protein, a homolog of bacterial RecA (TIGR02012), eukaryotic RAD51 (TIGR02239) and DMC1 (TIGR02238), and archaeal RadA (TIGR02236).


Pssm-ID: 274047 [Multi-domain]  Cd Length: 209  Bit Score: 75.15  E-value: 1.74e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177   35 LDDALGvGGYPRGRIVEIYGPESSGKTTVALHAVAEVQKQGGTAAYIDAEnALDPVYAEHLGVNIDDLLLSQ------PD 108
Cdd:TIGR02237   1 IDELLG-GGVERGTITQIYGPPGSGKTNICMILAVNAARQGKKVVYIDTE-GLSPERFKQIAEDRPERALSNfivfevFD 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  109 TGEQGLEIADA--LVSSGAVDILVVDSVAALVpRAEIEGEMGDAHVGLQARLmsqalrKLSGTLNKTKTIALFI-NQIRE 185
Cdd:TIGR02237  79 FDEQGVAIQKTskFIDRDSASLVVVDSFTALY-RLELSDDRISRNRELARQL------TLLLSLARKKNLAVVItNQVYT 151

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 430769177  186 KVgvmfGNPETTP-GGRALKFY--ATIRLE----VRRAEQIKEGTNIIGNRVRIKVV 235
Cdd:TIGR02237 152 DV----NNGTLRPlGGHLLEHWskVILRLEkfrgRRLATLEKHRSRPEGESVYFRIT 204
radB PRK09361
DNA repair and recombination protein RadB; Provisional
 25-220 7.62e-16

DNA repair and recombination protein RadB; Provisional


Pssm-ID: 236482 [Multi-domain]  Cd Length: 225  Bit Score: 73.74  E-value: 7.62e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  25 ISTISSGSLALDDALGvGGYPRGRIVEIYGPESSGKTTVALHAVAEVQKQGGTAAYIDAEnALDPVYAEHL-GVNIDDLL 103
Cdd:PRK09361   2 DERLPTGCKMLDELLG-GGFERGTITQIYGPPGSGKTNICLQLAVEAAKNGKKVIYIDTE-GLSPERFKQIaGEDFEELL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177 104 ----LSQP-DTGEQGLEIADA-LVSSGAVDILVVDSVAALVpRAEIEGEM--GDAHVGLQARLmsQALRKLSgtlnKTKT 175
Cdd:PRK09361  80 sniiIFEPsSFEEQSEAIRKAeKLAKENVGLIVLDSATSLY-RLELEDEEdnSKLNRELGRQL--THLLKLA----RKHD 152

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 430769177 176 IA-LFINQIREKVgvmfGNPETTP-GGRALKFY--ATIRLE-----VRRAEQIK 220
Cdd:PRK09361 153 LAvVITNQVYSDI----DSDGLRPlGGHTLEHWskTILRLEkfrngKRRATLEK 202
Rad51 pfam08423
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ...
 22-218 1.21e-15

Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ATPase RecA protein.


Pssm-ID: 462471 [Multi-domain]  Cd Length: 255  Bit Score: 73.88  E-value: 1.21e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177   22 QTTISTISSGSLALDDALGvGGYPRGRIVEIYGPESSGKT----TVALHAVAEVQKQG--GTAAYIDAENALDPV----Y 91
Cdd:pfam08423  13 RSELIQITTGSKELDKLLG-GGIETGSITEIFGEFRTGKTqlchTLCVTCQLPLEMGGgeGKALYIDTEGTFRPErlvaI 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177   92 AEHLGVNIDDLLLSQP-------DTGEQGLEIADALVSSGAVDILVVDSVAALVpRAEIE--GEMGDAHVGLqARLMSqA 162
Cdd:pfam08423  92 AERYGLDPEDVLDNVAyaraynsEHQMQLLQQAAAMMSESRFALLIVDSATALY-RTDFSgrGELAERQQHL-AKFLR-T 168

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 430769177  163 LRKLSGTLNktktIALFI-NQIREKVG---VMF-GNPETTPGGRALKFYATIRLEVR--RAEQ 218
Cdd:pfam08423 169 LQRLADEFG----VAVVItNQVVAQVDgaaGMFsGDPKKPIGGHIMAHASTTRLSLRkgRGEQ 227
DMC1 cd19514
homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in ...
 28-218 6.54e-14

homologous-pairing protein DMC1; DMC1 has a central role in homologous recombination in meiosis. It assembles at the sites of programmed DNA double-strand breaks and carries out a search for allelic DNA sequences located on homologous chromatids. It forms octameric rings.


Pssm-ID: 410922 [Multi-domain]  Cd Length: 236  Bit Score: 68.54  E-value: 6.54e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  28 ISSGSLALDDALGvGGYPRGRIVEIYGPESSGKTTVAlHAVAeVQKQ--------GGTAAYIDAENALDP----VYAEHL 95
Cdd:cd19514    1 ISTGSTELDKLLG-GGIESMSITEVFGEFRTGKTQLS-HTLC-VTAQlpgsmgggGGKVAYIDTEGTFRPdrirPIAERF 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  96 GVN----IDDLLLSQPDTGEQGLEIADALVSSGAVD----ILVVDSVAALVpRAEI--EGEMGDAHVGLqARLMSQaLRK 165
Cdd:cd19514   78 GVDhdavLDNILYARAYTSEHQMELLDYVAAKFHEEavfrLLIIDSIMALF-RVDFsgRGELAERQQKL-AQMLSR-LQK 154

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 430769177 166 LSGTLNktktIALFI-NQIREKVG--VMF-GNPETTPGGRALKFYATIRLEVR--RAEQ 218
Cdd:cd19514  155 ISEEYN----VAVFItNQVTADPGaaMTFqADPKKPIGGHILAHASTTRISLRkgRGEE 209
archRadA cd19515
archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a ...
 28-215 4.60e-13

archaeal recombinase Rad51/RadA; This group includes the archaeal protein RadA which is a homolog of Rad51. RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR)


Pssm-ID: 410923 [Multi-domain]  Cd Length: 233  Bit Score: 66.23  E-value: 4.60e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  28 ISSGSLALDDALGvGGYPRGRIVEIYGPESSGKTTVALHAVAEVQKQ------GGTAAYIDAENALDP----VYAEHLGV 97
Cdd:cd19515    1 ISTGSKELDKLLG-GGIETQAITEVFGEFGSGKTQLCHQLAVNVQLPpeegglNGKAVYIDTENTFRPerimQMAKALGL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  98 NIDDLL-----LSQPDTGEQGL---EIADALVSSGAVDILVVDSVAALVpRAEI--EGEMGDAHVGLqARLMSQaLRKLS 167
Cdd:cd19515   80 DPDEVLdniyvARAYNSNHQMLlveKAEDLIKEGNNIKLLIVDSLTSHF-RAEYvgRGTLAERQQKL-NKHLHD-LHRLA 156

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 430769177 168 GTLNktktIALFI-NQIREKVGVMFGNPETTPGGRALKFYATIRLEVRR 215
Cdd:cd19515  157 DLYN----IAVLVtNQVMAKPDAFFGDPTQAIGGHILGHAATFRVYLRK 201
PTZ00035 PTZ00035
Rad51 protein; Provisional
 21-218 1.47e-12

Rad51 protein; Provisional


Pssm-ID: 185407 [Multi-domain]  Cd Length: 337  Bit Score: 65.79  E-value: 1.47e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  21 AQTTISTISSGSLALDDALGvGGYPRGRIVEIYGPESSGKTTVAlHAVA-------EVQKQGGTAAYIDAENALDP---- 89
Cdd:PTZ00035  93 ARKNIIRITTGSTQLDKLLG-GGIETGSITELFGEFRTGKTQLC-HTLCvtcqlpiEQGGGEGKVLYIDTEGTFRPeriv 170

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  90 VYAEHLGVNIDDLL----LSQPDTGEQGLEI---ADALVSSGAVDILVVDSVAALVpRAEI--EGEMGDAHVGLqARLMS 160
Cdd:PTZ00035 171 QIAERFGLDPEDVLdniaYARAYNHEHQMQLlsqAAAKMAEERFALLIVDSATALF-RVDYsgRGELAERQQHL-GKFLR 248

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 430769177 161 qALRKLSGTLNktktIALFI-NQIREKVG---VMFGNPETTPGGRALKFYATIRLEVR--RAEQ 218
Cdd:PTZ00035 249 -ALQKLADEFN----VAVVItNQVMADVDgasMFVADPKKPIGGHIIAHASTTRLSLRkgRGEQ 307
Rad51 cd19513
RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous ...
 28-218 1.69e-12

RAD51D recombinase; RAD51 recombinase plays an essential role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51 is recruited to the break site with the help of its paralogs, RAD51D, RAD51B, RAD51C, XRCC3, and XRCC2, where it forms long helical polymers which wrap around the ssDNA tail at the break which leads to pairing and strand invasion.


Pssm-ID: 410921 [Multi-domain]  Cd Length: 235  Bit Score: 64.65  E-value: 1.69e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  28 ISSGSLALDDALGvGGYPRGRIVEIYGPESSGKT----TVALHAVAEVQKQG--GTAAYIDAENALDPV----YAEHLGV 97
Cdd:cd19513    1 ITTGSKELDKLLG-GGIETGSITELFGEFRTGKTqlchTLAVTCQLPIDQGGgeGKALYIDTEGTFRPErllaIAERYGL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  98 NIDDLLLS-------QPDTGEQGLEIADALVSSGAVDILVVDSVAALVpRAEIEGEmGDahvgLQARLMS-----QALRK 165
Cdd:cd19513   80 NGEDVLDNvayarayNTDHQMQLLIQASAMMAESRYALLIVDSATALY-RTDYSGR-GE----LSARQMHlakflRMLQR 153

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 430769177 166 LSGTLNktktIALFI-NQIREKV--GVMFGNPETTP-GGRALKFYATIRLEVR--RAEQ 218
Cdd:cd19513  154 LADEFG----VAVVItNQVVAQVdgAAMFAGDPKKPiGGNIMAHASTTRLYLRkgRGET 208
Rad51_DMC1_archRadA cd01123
recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic ...
 28-215 1.82e-12

recombinase Rad51, DMC1, and archaeal RadA; This group of recombinases includes the eukaryotic proteins RAD51, RAD55/57 and the meiosis-specific protein DMC1, and the archaeal protein RadA. They are closely related to the bacterial RecA group. Rad51 proteins catalyze a similar recombination reaction as RecA, using ATP-dependent DNA binding activity and a DNA-dependent ATPase. However, this reaction is less efficient and requires accessory proteins such as RAD55/57 .


Pssm-ID: 410868 [Multi-domain]  Cd Length: 234  Bit Score: 64.86  E-value: 1.82e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  28 ISSGSLALDDALGvGGYPRGRIVEIYGPESSGKTTVAlHAVA-------EVQKQGGTAAYIDAENALDPV----YAEHLG 96
Cdd:cd01123    1 ITTGSKELDKLLG-GGIETGSITEMFGEFRTGKTQLC-HTLAvtcqlpiDRGGGEGKAIYIDTEGTFRPErlraIAQRFG 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  97 VNIDDLLLS-------QPDTGEQGLEIADALVSSGAVDILVVDSVAALVpRAEI--EGEMGDAHVGLqARLMSqALRKLS 167
Cdd:cd01123   79 LDPDDVLDNvayarafNSDHQTQLLDQAAAMMVESRFKLLIVDSATALY-RTDYsgRGELSARQMHL-AKFLR-MLQRLA 155

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 430769177 168 GTLNktktIALFI-NQIREKVG---VMFGNPETTPGGRALKFYATIRLEVRR 215
Cdd:cd01123  156 DEFG----VAVVVtNQVVAQVDgamMFAADPKKPIGGNILAHASTTRLYLRK 203
PLN03187 PLN03187
meiotic recombination protein DMC1 homolog; Provisional
 28-218 2.01e-12

meiotic recombination protein DMC1 homolog; Provisional


Pssm-ID: 215620 [Multi-domain]  Cd Length: 344  Bit Score: 65.57  E-value: 2.01e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  28 ISSGSLALDDALGvGGYPRGRIVEIYGPESSGKTTVAlHAVA-----EVQKQGGTA--AYIDAENALDP----VYAEHLG 96
Cdd:PLN03187 108 ITTGSQALDELLG-GGIETRCITEAFGEFRSGKTQLA-HTLCvttqlPTEMGGGNGkvAYIDTEGTFRPdrivPIAERFG 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  97 VN----IDDLLLSQPDTGEQgleIADALVSSGA------VDILVVDSVAALVpRAEI--EGEMGDAHVGLqARLMSQaLR 164
Cdd:PLN03187 186 MDadavLDNIIYARAYTYEH---QYNLLLGLAAkmaeepFRLLIVDSVIALF-RVDFtgRGELAERQQKL-AQMLSR-LT 259

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 430769177 165 KLSGTLNktktIALFI-NQIREKVG--VMFGNPETTPGGRALKFYATIRLEVR--RAEQ 218
Cdd:PLN03187 260 KIAEEFN----VAVYMtNQVIADPGggMFISDPKKPAGGHVLAHAATIRLMLRkgKGEQ 314
PLN03186 PLN03186
DNA repair protein RAD51 homolog; Provisional
 16-215 2.58e-12

DNA repair protein RAD51 homolog; Provisional


Pssm-ID: 178728 [Multi-domain]  Cd Length: 342  Bit Score: 65.14  E-value: 2.58e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  16 RMGDAAQTTISTISSGSLALDDALGvGGYPRGRIVEIYGPESSGKT----TVALHAVAEVQKQGGT--AAYIDAENALDP 89
Cdd:PLN03186  93 SQLHAQRQEIIQITTGSRELDKILE-GGIETGSITEIYGEFRTGKTqlchTLCVTCQLPLDQGGGEgkAMYIDTEGTFRP 171

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  90 ----VYAEHLGVNIDDLL----LSQPDTGEQGLEI---ADALVSSGAVDILVVDSVAALVpRAEIEGEmGDahvgLQAR- 157
Cdd:PLN03186 172 qrliQIAERFGLNGADVLenvaYARAYNTDHQSELlleAASMMAETRFALMIVDSATALY-RTEFSGR-GE----LSARq 245

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 430769177 158 -LMSQALRKLSgTLNKTKTIALFI-NQIREKV--GVMFGNPETTP-GGRALKFYATIRLEVRR 215
Cdd:PLN03186 246 mHLGKFLRSLQ-RLADEFGVAVVItNQVVAQVdgSAFFAGPQLKPiGGNIMAHASTTRLALRK 307
radA PRK04301
DNA repair and recombination protein RadA; Validated
 24-216 2.85e-12

DNA repair and recombination protein RadA; Validated


Pssm-ID: 235273 [Multi-domain]  Cd Length: 317  Bit Score: 64.90  E-value: 2.85e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  24 TISTISSGSLALDDALGvGGYPRGRIVEIYGPESSGKTTVALHAVAEVQ---KQGG---TAAYIDAENALDP----VYAE 93
Cdd:PRK04301  80 NVGKITTGSKELDELLG-GGIETQSITEFYGEFGSGKTQICHQLAVNVQlpeEKGGlegKAVYIDTEGTFRPerieQMAE 158

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  94 HLGVNIDDLL-----LSQPDTGEQGL--EIADALVSSG-AVDILVVDSVAALVpRAEiegemgdaHVGL------QARLM 159
Cdd:PRK04301 159 ALGLDPDEVLdnihvARAYNSDHQMLlaEKAEELIKEGeNIKLVIVDSLTAHF-RAE--------YVGRgnlaerQQKLN 229

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 430769177 160 SQ--ALRKLSGTLNktkTIALFINQIREKVGVMFGNPETTPGGRALKFYATIRLEVRRA 216
Cdd:PRK04301 230 KHlhDLLRLADLYN---AAVVVTNQVMARPDAFFGDPTQPIGGHILGHTATFRIYLRKS 285
RAD55 COG0467
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];
28-195 5.31e-12

RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];


Pssm-ID: 440235 [Multi-domain]  Cd Length: 221  Bit Score: 63.01  E-value: 5.31e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  28 ISSGSLALDDALGvGGYPRGRIVEIYGPESSGKTTVALHAVAEVQKQGGTAAYIDAENALDPV--YAEHLGVNIDDLL-- 103
Cdd:COG0467    2 VPTGIPGLDELLG-GGLPRGSSTLLSGPPGTGKTTLALQFLAEGLRRGEKGLYVSFEESPEQLlrRAESLGLDLEEYIes 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177 104 -----------LSQPDTGEQGLEIADALVSSGAvDILVVDSVAALvpRAEIEGEMgdahvglQARLMsqaLRKLSGTLNK 172
Cdd:COG0467   81 gllriidlspeELGLDLEELLARLREAVEEFGA-KRVVIDSLSGL--LLALPDPE-------RLREF---LHRLLRYLKK 147

                        170       180
                 ....*....|....*....|...
gi 430769177 173 TKTIALFINQIREKVGVMFGNPE 195
Cdd:COG0467  148 RGVTTLLTSETGGLEDEATEGGL 170
recomb_DMC1 TIGR02238
meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA ...
 28-218 1.20e-11

meiotic recombinase Dmc1; This model describes DMC1, a subfamily of a larger family of DNA repair and recombination proteins. It is eukaryotic only and most closely related to eukaryotic RAD51. It also resembles archaeal RadA (TIGR02236) and RadB (TIGR02237) and bacterial RecA (TIGR02012). It has been characterized for human as a recombinase active only in meiosis.


Pssm-ID: 131292 [Multi-domain]  Cd Length: 313  Bit Score: 63.26  E-value: 1.20e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177   28 ISSGSLALDDALGvGGYPRGRIVEIYGPESSGKTTVA--LHAVAEVQKQGGTA----AYIDAENALDP----VYAEHLGV 97
Cdd:TIGR02238  78 ITTGSQALDGILG-GGIESMSITEVFGEFRCGKTQLShtLCVTAQLPREMGGGngkvAYIDTEGTFRPdrirAIAERFGV 156

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177   98 N----IDDLLLSQPDTGEQGLEIAD---ALVSSGAVDILVVDSVAALVpRAEI--EGEMGDAHVGLqARLMSQaLRKLSG 168
Cdd:TIGR02238 157 DpdavLDNILYARAYTSEHQMELLDylaAKFSEEPFRLLIVDSIMALF-RVDFsgRGELSERQQKL-AQMLSR-LNKISE 233

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 430769177  169 TLNktktIALFI-NQIREKVG--VMF-GNPETTPGGRALKFYATIRLEVR--RAEQ 218
Cdd:TIGR02238 234 EFN----VAVFVtNQVQADPGatMTFiADPKKPIGGHVLAHASTTRILLRkgRGEE 285
Rad51B cd19493
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair ...
 36-215 7.91e-11

RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51B, together with the other RAD51 paralogs, RAD51C, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site.


Pssm-ID: 410901 [Multi-domain]  Cd Length: 222  Bit Score: 60.03  E-value: 7.91e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  36 DDALGvGGYPRGRIVEIYGPESSGKTTVALHAVAEV----QKQGGTAA--YIDAENAL------------DPVY------ 91
Cdd:cd19493    1 DTALA-GGLPLGAITEITGASGSGKTQFALTLASSAampaRKGGLDGGvlYIDTESKFsaerlaeiaearFPEAfsgfme 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  92 -AEHLGVNIDDLLLSQPDTGEQGLEIADAL---VSSGAVDILVVDSVAALVpRAEIEGEMGDA---HVGLqARLMSqALR 164
Cdd:cd19493   80 eNERAEEMLKRVAVVRVTTLAQLLERLPNLeehILSSGVRLVVIDSIAALV-RREFGGSDGEVterHNAL-AREAS-SLK 156

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 430769177 165 KLSGTLNKTktiALFINQIREKVG-VMFGNPETTPG-GRALKFYATIRLEVRR 215
Cdd:cd19493  157 RLAEEFRIA---VLVTNQATTHFGdAGDGSSGVTAAlGDAWAHAVNTRLRLER 206
recomb_RAD51 TIGR02239
DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein ...
 25-215 1.13e-10

DNA repair protein RAD51; This eukaryotic sequence family consists of RAD51, a protein involved in DNA homologous recombination and repair. It is similar in sequence the exclusively meiotic recombinase DMC1 (TIGR02238), to archaeal families RadA (TIGR02236) and RadB (TIGR02237), and to bacterial RecA (TIGR02012).


Pssm-ID: 274048 [Multi-domain]  Cd Length: 316  Bit Score: 60.51  E-value: 1.13e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177   25 ISTISSGSLALDDALGvGGYPRGRIVEIYGPESSGKT----TVALHAVAEVQKQG--GTAAYIDAENALDPV----YAEH 94
Cdd:TIGR02239  75 VIQLTTGSKELDKLLG-GGIETGSITEIFGEFRTGKTqlchTLAVTCQLPIDQGGgeGKALYIDTEGTFRPErllaIAER 153

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177   95 LGVNIDDLLLS-------QPDTGEQGLEIADALVSSGAVDILVVDSVAALVpRAEIEGEmGDahvgLQARLMSQA--LRK 165
Cdd:TIGR02239 154 YGLNPEDVLDNvayarayNTDHQLQLLQQAAAMMSESRFALLIVDSATALY-RTDFSGR-GE----LSARQMHLArfLRS 227

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 430769177  166 LSgTLNKTKTIALFI-NQIREKV---GVMFGNPETTP-GGRALKFYATIRLEVRR 215
Cdd:TIGR02239 228 LQ-RLADEFGVAVVItNQVVAQVdgaGSMFAGDPKKPiGGNIMAHASTTRLSLRK 281
COG4544 COG4544
Uncharacterized conserved protein [Function unknown];
11-132 2.33e-10

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443609 [Multi-domain]  Cd Length: 230  Bit Score: 58.79  E-value: 2.33e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  11 KGAIMRMGDAAQTTISTISSGSLALDDALGVGGYPRGRIVEIYGPE-SSGKTTVALHAVAEVQKQGGTAAYIDAENALDP 89
Cdd:COG4544   12 RRRIWRGEGLAAAARAVLPTGFAALDAALPGGGLPRGALHEILGPApGIGELGLLLPLLARLAQAGGPVLWIAPPYDLYA 91

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 430769177  90 VYAEHLGVNIDDLLLSQPDTGEQGLEIADALVSSGAVDILVVD 132
Cdd:COG4544   92 PGLAAAGLDPERLLLVRARRPADALWAAEEALRSGACGAVVAW 134
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 46-217 6.28e-10

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 56.23  E-value: 6.28e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177    46 RGRIVEIYGPESSGKTTVALHAVAEVQKQGGTAAYIDAENALDPVYAEHLGVNIDDLLLSqpDTGEQGLEIADALVSSGA 125
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKAS--GSGELRLRLALALARKLK 78

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177   126 VDILVVDSVAALVPRaeiegemgdahVGLQARLMSQALRKLSGTLNKTKTIALFINqirekvgvmfgNPETTPGGRALKF 205
Cdd:smart00382  79 PDVLILDEITSLLDA-----------EQEALLLLLEELRLLLLLKSEKNLTVILTT-----------NDEKDLGPALLRR 136

                          170
                   ....*....|..
gi 430769177   206 YATIRLEVRRAE 217
Cdd:smart00382 137 RFDRRIVLLLIL 148
XRCC3 cd19491
XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells ...
 35-188 2.03e-07

XRCC3 recombinase; XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells 3) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC3, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC2, helps recruit RAD51 to the break site.


Pssm-ID: 410899 [Multi-domain]  Cd Length: 250  Bit Score: 50.37  E-value: 2.03e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  35 LDDALGvGGYPRGRIVEIYGPESSGKTTVALHAVAEVQ------KQGGTAAYIDAENAL----------------DPVYA 92
Cdd:cd19491    1 LDELLG-GGIPVGGITEIAGESGAGKTQLCLQLALTVQlprelgGLGGGAVYICTESSFpskrlqqlasslpkryHLEKA 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  93 EHLGVNIDDLLLSQPDTGEQGL-EIADALVSSGAVDILVVDSVAALVpRAEIEGEMGDahVGLQARLMSQ---ALRKLSG 168
Cdd:cd19491   80 KNFLDNIFVEHVADLETLEHCLnYQLPALLERGPIRLVVIDSIAALF-RSEFDTSRSD--LVERAKYLRRladHLKRLAD 156

                        170       180
                 ....*....|....*....|.
gi 430769177 169 TLNktktIA-LFINQIREKVG 188
Cdd:cd19491  157 KYN----LAvVVVNQVTDRFD 173
KaiC-like cd01124
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. ...
 28-186 5.13e-07

Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.


Pssm-ID: 410869 [Multi-domain]  Cd Length: 222  Bit Score: 48.80  E-value: 5.13e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  28 ISSGSLALDDALGvGGYPRGRIVEIYGPESSGKTTVALHAVAEVQKQGGTAAYIDAE--------NALDPVYAEHLGVNI 99
Cdd:cd01124    1 VKTGIPGLDELLG-GGIPKGSVTLLTGGPGTGKTLFGLQFLYAGAKNGEPGLFFTFEesperllrNAKSFGWDFDEMEDE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177 100 DDLLLSQPDTGEQGLEIADALVS-------SGAVDILVVDSVAALvpRAEIEGEMgdahvglQARlmsQALRKLSGTLNK 172
Cdd:cd01124   80 GKLIIVDAPPTEAGRFSLDELLSrilsiikSFKAKRVVIDSLSGL--RRAKEDQM-------RAR---RIVIALLNELRA 147

                        170
                 ....*....|....
gi 430769177 173 TKTIALFINQIREK 186
Cdd:cd01124  148 AGVTTIFTSEMRSF 161
ATPase pfam06745
KaiC; This family is in the P-loop NTPase superfamily and is found in archaea, bacteria and ...
 35-226 7.26e-07

KaiC; This family is in the P-loop NTPase superfamily and is found in archaea, bacteria and eukaryotes. More than one copy is sometimes found in each protein. This family includes KaiC, which is one of the Kai proteins among which direct protein-protein association may be a critical process in the generation of circadian rhythms in cyanobacteria.


Pssm-ID: 429095 [Multi-domain]  Cd Length: 231  Bit Score: 48.40  E-value: 7.26e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177   35 LDDALGvGGYPRGRIVEIYGPESSGKTTVALH-AVAEVQKQGGTAAYIDAENalDPV----YAEHLGVNIDDLL------ 103
Cdd:pfam06745   8 LDEILK-GGFPEGRVVLITGGPGTGKTIFGLQfLYNGALKYGEPGVFVTLEE--PPEdlreNARSFGWDLEKLEeegkla 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  104 ---LSQPDTGEQGLEIADAL----------VSSGAVDILVVDSVAALvprAEIEGEMgdahvglQARlmsQALRKLSGTL 170
Cdd:pfam06745  85 iidASTSGIGIAEVEDRFDLeelierlreaIREIGAKRVVIDSITTL---FYLLKPA-------VAR---EILRRLKRVL 151

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 430769177  171 NKTKTIALFINQIREKvgvmfgnpETTPGGRALKFYA---TIRLEVRRAEQIKEGTNII 226
Cdd:pfam06745 152 KGLGVTAIFTSEKPSG--------EGGIGGYGVEEFIvdgVIRLDLKEIEEERVRTIEI 202
RadA_SMS_N cd01121
bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a ...
 28-180 9.41e-06

bacterial RadA DNA repair protein; Sms or bacterial RadA is a DNA repair protein that plays a role in recombination and recombinational repair of DNA damaged by UV radiation, X-rays, and chemical agent and is responsible for the stabilization or processing of branched DNA molecules.


Pssm-ID: 410866 [Multi-domain]  Cd Length: 268  Bit Score: 45.60  E-value: 9.41e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  28 ISSGSLALDDALGvGGYPRGRIVEIYGPESSGKTTVALHAVAEVQKQGGTAAYIDAENALDPV--YAEHLGVNIDDLLLs 105
Cdd:cd01121   64 ISTGIGELDRVLG-GGLVPGSVVLIGGDPGIGKSTLLLQVAARLAQRGGKVLYVSGEESLSQIklRAERLGLGSDNLYL- 141

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 430769177 106 qpdTGEQGLEIADALVSSGAVDILVVDSVAALVpRAEIEGEMGDAhvgLQARLMSQALRKLSgtlnKTKTIALFI 180
Cdd:cd01121  142 ---LAETNLEAILAEIEELKPSLVVIDSIQTVY-SPELTSSPGSV---SQVRECAAELLRLA----KETGIPVFL 205
KaiC-like_N cd19488
N-terminal domain of KaiC family protein; uncharacterized subfamily; KaiC is a circadian clock ...
 28-100 1.45e-05

N-terminal domain of KaiC family protein; uncharacterized subfamily; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.


Pssm-ID: 410896 [Multi-domain]  Cd Length: 225  Bit Score: 44.65  E-value: 1.45e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 430769177  28 ISSGSLALDDALGvGGYPRGRIVEIYGPESSGKTTVALHAVAEVQKQGGTAAYI---DAENALDPVYAEHlGVNID 100
Cdd:cd19488    1 ISTGIPGLDDILR-GGLPPRRLYLVEGAPGTGKTTLALQFLLEGAANGETGLYItlsETEQELRAVALSH-GWSLD 74
XRCC2 cd19490
XRCC2 recombinase; XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells ...
 47-215 1.99e-05

XRCC2 recombinase; XRCC2 (X-ray repair complementing defective repair in Chinese hamster cells 2) recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. XRCC2, together with the other RAD51 paralogs, RAD51B, RAD51C, RAD51D, and XRCC3, helps recruit RAD51 to the break site.


Pssm-ID: 410898 [Multi-domain]  Cd Length: 226  Bit Score: 44.26  E-value: 1.99e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  47 GRIVEIYGPESSGKTTVALHAVA---------EVQKQGGTAA--YIDAENALDPV----YAEHLGVNIDDLLLSQPDTGE 111
Cdd:cd19490    1 GDVIEITGPSGSGKTELLYHLAArcilpsswgGVPLGGLEAAvvFIDTDGRFDILrlrsILEARIRAAIQAANSSDDEED 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177 112 QGLEIADAL----------------------------VSSGAVDILVVDSVAALVPRAEIEGEMGDAHVGLQARLM---S 160
Cdd:cd19490   81 VEEIARECLqrlhifrchsslqllatllslenyllslSANPELGLLLIDSISAFYWQDRFSAELARAAPLLQEAALraiL 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 430769177 161 QALRKLSGTLNK----TKTialFINQIREKVGVMFGNPETTPGGRALKF----------YATIRLEVRR 215
Cdd:cd19490  161 RELRRLRRRFQLvviaTKQ---ALFPGKSASTDNPAANNAVSKASAPSHreylprpwqrLVTHRLVLSR 226
KaiC-like_C cd19487
C-terminal domain of KaiC family protein; uncharacterized subfamily; KaiC is a circadian clock ...
 28-135 6.05e-05

C-terminal domain of KaiC family protein; uncharacterized subfamily; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.


Pssm-ID: 410895 [Multi-domain]  Cd Length: 219  Bit Score: 42.67  E-value: 6.05e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  28 ISSGSLALDDALGvGGYPRGRIVEIYGPESSGKTTVALHAVAEVQKQGGTAAYIDAENALDPVY--AEHLGVNIDDLLls 105
Cdd:cd19487    1 VSSGVPELDELLG-GGLERGTSTLLIGPAGVGKSTLALQFAKAAAARGERSVLFSFDESIGTLFerSEALGIDLRAMV-- 77

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 430769177 106 qpDTGEQGLEIADAL--------------VSSGAVDILVVDSVA 135
Cdd:cd19487   78 --EKGLLSIEQIDPAelspgefaqrvrtsVEQEDARVVVIDSLN 119
RecA-like_superfamily cd01120
RecA-like_NTPases; RecA-like NTPases. This superfamily includes the NTP binding domain of F1 ...
 50-204 2.41e-04

RecA-like_NTPases; RecA-like NTPases. This superfamily includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410865 [Multi-domain]  Cd Length: 119  Bit Score: 39.79  E-value: 2.41e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  50 VEIYGPESSGKTTVALHAVAEVQKQGGTAAYIDaenALDPVyaehlgvniddlllsqpdtgeqgLEIADALVSSGAVDIL 129
Cdd:cd01120    1 ILITGPPGSGKTTLLLQFAEQALLSDEPVIFIS---FLDTI-----------------------LEAIEDLIEEKKLDII 54

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 430769177 130 VVDSVAALVPRAEiegemgdahvGLQARLMSQALRKLSGTLNKTKTIALFINQIREKVGVMFGNPETTPGGRALK 204
Cdd:cd01120   55 IIDSLSSLARASQ----------GDRSSELLEDLAKLLRAARNTGITVIATIHSDKFDIDRGGSSNDERLLKSLR 119
KaiC_C cd19484
C-terminal domain of Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most ...
 28-100 4.21e-04

C-terminal domain of Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.


Pssm-ID: 410892 [Multi-domain]  Cd Length: 218  Bit Score: 40.39  E-value: 4.21e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 430769177  28 ISSGSLALDDALGVGGYPRGRIVEIYGPESSGKTTVALHAVAEVQKQGGTAAYIDAENALDPVYAEHLGVNID 100
Cdd:cd19484    1 ISTGIPRLDAMLGGGGFFRGSSILVSGATGTGKTLLAASFADAACRRGERCLYFAFEESPAQLIRNAKSIGID 73
RepA COG3598
RecA-family ATPase [Replication, recombination and repair];
45-242 4.45e-04

RecA-family ATPase [Replication, recombination and repair];


Pssm-ID: 442817 [Multi-domain]  Cd Length: 313  Bit Score: 40.65  E-value: 4.45e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177  45 PRGRIVEIYGPESSGKTTVALHAVAEV---------QKQGGTAAYIDAENALDPV------YAEHLGVNIDDLL------ 103
Cdd:COG3598   11 PEGGVTLLAGPPGTGKSFLALQLAAAVaaggpwlgrRVPPGKVLYLAAEDDRGELrrrlkaLGADLGLPFADLDgrlrll 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177 104 -LSQPDTGEQGLEIADALVSSGAVDILVVDSVAALVPraeiegemGDAHVGLQARLMSQALRKLSGTLNKTktiALFINQ 182
Cdd:COG3598   91 sLAGDLDDTDDLEALERAIEEEGPDLVVIDPLARVFG--------GDENDAEEMRAFLNPLDRLAERTGAA---VLLVHH 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177 183 IReKVGVMFGNPETTPGGRALKFYATIRLEVRRAEQikegtniiGNRVRIKVVKNKVAPP 242
Cdd:COG3598  160 TG-KGGAGKDSGDRARGSSALRGAARSVLVLSREKG--------EDLRVLTRAKSNYGPE 210
PRK09302 PRK09302
circadian clock protein KaiC; Reviewed
 28-84 5.78e-04

circadian clock protein KaiC; Reviewed


Pssm-ID: 236461 [Multi-domain]  Cd Length: 509  Bit Score: 40.63  E-value: 5.78e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 430769177  28 ISSGSLALDDALGvGGYPRGRIVEIYGPESSGKTTVALHAVAEVQKQGGTAAYIDAE 84
Cdd:PRK09302 255 ISSGVPDLDEMLG-GGFFRGSIILVSGATGTGKTLLASKFAEAACRRGERCLLFAFE 310
Rad51D cd19489
RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair ...
 42-87 1.11e-03

RAD51D recombinase; RAD51D recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51D, together with the other RAD51 paralogs, RAD51B, RAD51C, XRCC3, and XRCC2, helps recruit RAD51 to the break site.


Pssm-ID: 410897 [Multi-domain]  Cd Length: 209  Bit Score: 39.16  E-value: 1.11e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 430769177  42 GGYPRGRIVEIYGPESSGKTTVALHAVAEVQKQGG-TAAYIDAENAL 87
Cdd:cd19489    2 GGLRTGEITELVGESSSGKTQLCLTAAANVASRSGqNVLYIDTKSSF 48
AAA_24 pfam13479
AAA domain; This AAA domain is found in a wide variety of presumed phage proteins.
 46-134 9.29e-03

AAA domain; This AAA domain is found in a wide variety of presumed phage proteins.


Pssm-ID: 433243  Cd Length: 199  Bit Score: 36.15  E-value: 9.29e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 430769177   46 RGRIVEIYGPESSGKTTVALHAvaevqkqgGTAAYIDAENALDPVYAEHLGVniDDLLLSQPDTGEQGLEIADALVSSga 125
Cdd:pfam13479   1 KKLKILIYGPSGIGKTTFAKTL--------PKPLFLDTEKGSKALDGDRFPD--IVIRDSWQDFLDAIDELTAAELAD-- 68


                  ....*....
gi 430769177  126 VDILVVDSV 134
Cdd:pfam13479  69 YKTIVIDTV 77
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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