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Conserved domains on  [gi|633897531|gb|AHZ58945|]
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maltose ABC transporter permease [Lactiplantibacillus plantarum]

Protein Classification

carbohydrate ABC transporter permease( domain architecture ID 10003067)

carbohydrate ABC transporter permease is the transmembrane (TM) subunit of a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter responsible for the translocation across the membrane of one or more from a variety of carbohydrate substrates including trehalose, lactose, arabinose, and maltodextrin

Gene Ontology:  GO:0042626|GO:0140359|GO:0008643|GO:0055085
PubMed:  25750732|24638992|30626703
TCDB:  3.A.1.1.-

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
malF super family cl35979
maltose ABC transporter permease MalF;
167-422 1.77e-55

maltose ABC transporter permease MalF;


The actual alignment was detected with superfamily member PRK10999:

Pssm-ID: 236816 [Multi-domain]  Cd Length: 520  Bit Score: 191.71  E-value: 1.77e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 167 WIGFKNFTSMFFLSSYRATFNAVFGWTVIWTVCATTLQIIIGIATAVIANQNFIKGKRFFGVIFLLPWAIPAFVSIMSFS 246
Cdd:PRK10999 264 TIGWKNFTRVFTDEGIQKPFIAIFIWTVVFSLLTVVLTVAVGMVLACLVQWEALKGKAVYRVLLILPYAVPSFISILIFK 343

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 247 NIFNDSAGAINVQVIGLWNtlvpfahIAPiHWMTDTFWTKVAIIMIQGWLGFPYIYVMITGILQAIPEDLYEAATLDGAT 326
Cdd:PRK10999 344 GLFNQSFGEINMMLSALFG-------IKP-AWFSDPTLAKTMILIVNTWLGYPYMMILCMGLLKAIPDDLYEASAMDGAG 415

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 327 VMQKFNKITLPTIFAIAAPIFVTQYTFNFNNFSMIYLFNQGGPGDVGAN--AGGTDILISWIYKLT-TGTSPQ-YSLAAA 402
Cdd:PRK10999 416 PFQNFFKITLPLLIKPLTPLMIASFAFNFNNFVLIQLLTNGGPDMIGTTtpAGYTDLLVSYTYRIAfEGGGGQdFGLAAA 495

                        250       260
                 ....*....|....*....|
gi 633897531 403 VTLIISVLVIGISLIVFKKT 422
Cdd:PRK10999 496 IATLIFLLVGALAILNLKAT 515
 
Name Accession Description Interval E-value
malF PRK10999
maltose ABC transporter permease MalF;
167-422 1.77e-55

maltose ABC transporter permease MalF;


Pssm-ID: 236816 [Multi-domain]  Cd Length: 520  Bit Score: 191.71  E-value: 1.77e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 167 WIGFKNFTSMFFLSSYRATFNAVFGWTVIWTVCATTLQIIIGIATAVIANQNFIKGKRFFGVIFLLPWAIPAFVSIMSFS 246
Cdd:PRK10999 264 TIGWKNFTRVFTDEGIQKPFIAIFIWTVVFSLLTVVLTVAVGMVLACLVQWEALKGKAVYRVLLILPYAVPSFISILIFK 343

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 247 NIFNDSAGAINVQVIGLWNtlvpfahIAPiHWMTDTFWTKVAIIMIQGWLGFPYIYVMITGILQAIPEDLYEAATLDGAT 326
Cdd:PRK10999 344 GLFNQSFGEINMMLSALFG-------IKP-AWFSDPTLAKTMILIVNTWLGYPYMMILCMGLLKAIPDDLYEASAMDGAG 415

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 327 VMQKFNKITLPTIFAIAAPIFVTQYTFNFNNFSMIYLFNQGGPGDVGAN--AGGTDILISWIYKLT-TGTSPQ-YSLAAA 402
Cdd:PRK10999 416 PFQNFFKITLPLLIKPLTPLMIASFAFNFNNFVLIQLLTNGGPDMIGTTtpAGYTDLLVSYTYRIAfEGGGGQdFGLAAA 495

                        250       260
                 ....*....|....*....|
gi 633897531 403 VTLIISVLVIGISLIVFKKT 422
Cdd:PRK10999 496 IATLIFLLVGALAILNLKAT 515
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
120-420 4.02e-53

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 179.56  E-value: 4.02e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 120 DGGFAYLLTTPAYILMVFTIVFPVLVTLLMAFTNYDFAHIPPamllDWIGFKNFTSMFFlssyRATFNAVFGWTVIWTVC 199
Cdd:COG1175   16 RRLAAYLFLLPALLLLLVFVLYPLLYTLYLSFTDWNLLGPPP----EFVGLDNYARLFT----DPRFWNALGNTLLFTVV 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 200 ATTLQIIIGIATAVIANQNFiKGKRFFGVIFLLPWAIPAFVSIMSFSNIFNDSAGAINvqviglwnTLVPFAHIAPIHWM 279
Cdd:COG1175   88 SVPLQLVLGLLLALLLNRKL-RGRGFFRTLFFLPWVISPVVVALIWKWLFNPDYGLLN--------ALLGALGLEPINWL 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 280 TDTFWTKVAIIMIQGWLGFPYIYVMITGILQAIPEDLYEAATLDGATVMQKFNKITLPTIFAIAAPIFVTQYTFNFNNFS 359
Cdd:COG1175  159 GDPSLALPAVIIVTVWKGTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQVFD 238

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 633897531 360 MIYLFNQGGPGdvganaGGTDILISWIYKLTTgTSPQYSLAAAVTLIISVLVIGISLIVFK 420
Cdd:COG1175  239 LVYVLTGGGPG------NSTTTLVLYIYQTAF-QQFDFGYASAIAVVLFLIILVLTLLQLR 292
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 190-412 8.40e-10

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 58.06  E-value: 8.40e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 190 FGWTVIWTVCATTLQIIIGIATAVIANQNFIKGKRFFGVIFLLPWAIPAFVSIMSFSNIFNDSagainvqviglwntlvp 269
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVL----------------- 63

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 270 fahiapIHWMTDTFWTKVAIIMIQGWLgFPYIYVMITGILQAIPEDLYEAATLDGATVMQKFNKITLPTIFAIAAPIFVT 349
Cdd:cd06261   64 ------LGWGILPGLGLPALILALLLI-APFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVL 136

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 633897531 350 QYTFNFNNFSMIYLFNQGGPGdvganaggtdILISWIYKLTTGTSPQYSLAAAVTLIISVLVI 412
Cdd:cd06261  137 AFARALGEFALVSFLGGGEAP----------GPGTGLLLIFAILFPGDLGVAAAVALILLLLS 189
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 273-412 4.76e-08

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 52.69  E-value: 4.76e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531  273 IAPIHWMTDTFWTKVAIIMIQGWLGFPYIYVMITGILQAIPEDLYEAATLDGATVMQKFNKITLPTIFAIAAPIFVTQYT 352
Cdd:pfam00528  39 LVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFG 118

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531  353 FNFNNFSMIYLFNQGGPgdvganAGGTDILISWIYKLTTGTSPQYSLAAAVTLIISVLVI 412
Cdd:pfam00528 119 GALGGAVLLEFLGSWPG------LGLLLIEAILGYDYPEIQGPVLAAALILLLLNLLVDI 172
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 133-425 3.51e-07

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 52.38  E-value: 3.51e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531  133 ILMVFTIVFPVLVTLLMAFTNYDFahippamllDWIGFKNFTSMFFLSSyratFNAVFGWTVIWTVCATTLQIIIGIATA 212
Cdd:TIGR03262  12 LALLLFLLLPLLALLTKSVYDSDG---------DFIGLANFAEYFATPG----LLQSLGNSLTVSAIVTAIVVPLAFAFA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531  213 VIANQNFIKGKRFFGVIFLLPWAIPAFVSIMSFSNIFndsagainvqviGLWNTLVPFAHIAPIhwmtdtfWTKVAIIMI 292
Cdd:TIGR03262  79 YALTRSRIPGKGAFRLVALLPLLAPSLLPAISLIYLF------------GNQGLLKGLLGGFSI-------YGFWGIVIG 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531  293 QGWLGFPYIYVMITGILQAIPEDLYEAATLDGATVMQKFNKITLPTI-FAIAAPIFVTqYTFNFNNFsmiylfnqGGPGD 371
Cdd:TIGR03262 140 EVFYTFPHALMILVTALSLADGRLYEAARAMGASPWRTFFTVTLPGAkYGLISAAFVV-FTLVITDF--------GVPKV 210

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 633897531  372 VGanaGGTDILISWIYKLTTGTSpQYSLAAAVTLII---SVLVIGISLIVFKKTHAF 425
Cdd:TIGR03262 211 IG---GDYNVLATDIYKQVIGQQ-NFPMGAVVGVLLllpALLAFGIDRAIQRRQRAQ 263
 
Name Accession Description Interval E-value
malF PRK10999
maltose ABC transporter permease MalF;
167-422 1.77e-55

maltose ABC transporter permease MalF;


Pssm-ID: 236816 [Multi-domain]  Cd Length: 520  Bit Score: 191.71  E-value: 1.77e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 167 WIGFKNFTSMFFLSSYRATFNAVFGWTVIWTVCATTLQIIIGIATAVIANQNFIKGKRFFGVIFLLPWAIPAFVSIMSFS 246
Cdd:PRK10999 264 TIGWKNFTRVFTDEGIQKPFIAIFIWTVVFSLLTVVLTVAVGMVLACLVQWEALKGKAVYRVLLILPYAVPSFISILIFK 343

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 247 NIFNDSAGAINVQVIGLWNtlvpfahIAPiHWMTDTFWTKVAIIMIQGWLGFPYIYVMITGILQAIPEDLYEAATLDGAT 326
Cdd:PRK10999 344 GLFNQSFGEINMMLSALFG-------IKP-AWFSDPTLAKTMILIVNTWLGYPYMMILCMGLLKAIPDDLYEASAMDGAG 415

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 327 VMQKFNKITLPTIFAIAAPIFVTQYTFNFNNFSMIYLFNQGGPGDVGAN--AGGTDILISWIYKLT-TGTSPQ-YSLAAA 402
Cdd:PRK10999 416 PFQNFFKITLPLLIKPLTPLMIASFAFNFNNFVLIQLLTNGGPDMIGTTtpAGYTDLLVSYTYRIAfEGGGGQdFGLAAA 495

                        250       260
                 ....*....|....*....|
gi 633897531 403 VTLIISVLVIGISLIVFKKT 422
Cdd:PRK10999 496 IATLIFLLVGALAILNLKAT 515
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
120-420 4.02e-53

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 179.56  E-value: 4.02e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 120 DGGFAYLLTTPAYILMVFTIVFPVLVTLLMAFTNYDFAHIPPamllDWIGFKNFTSMFFlssyRATFNAVFGWTVIWTVC 199
Cdd:COG1175   16 RRLAAYLFLLPALLLLLVFVLYPLLYTLYLSFTDWNLLGPPP----EFVGLDNYARLFT----DPRFWNALGNTLLFTVV 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 200 ATTLQIIIGIATAVIANQNFiKGKRFFGVIFLLPWAIPAFVSIMSFSNIFNDSAGAINvqviglwnTLVPFAHIAPIHWM 279
Cdd:COG1175   88 SVPLQLVLGLLLALLLNRKL-RGRGFFRTLFFLPWVISPVVVALIWKWLFNPDYGLLN--------ALLGALGLEPINWL 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 280 TDTFWTKVAIIMIQGWLGFPYIYVMITGILQAIPEDLYEAATLDGATVMQKFNKITLPTIFAIAAPIFVTQYTFNFNNFS 359
Cdd:COG1175  159 GDPSLALPAVIIVTVWKGTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQVFD 238

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 633897531 360 MIYLFNQGGPGdvganaGGTDILISWIYKLTTgTSPQYSLAAAVTLIISVLVIGISLIVFK 420
Cdd:COG1175  239 LVYVLTGGGPG------NSTTTLVLYIYQTAF-QQFDFGYASAIAVVLFLIILVLTLLQLR 292
LplB COG4209
ABC-type polysaccharide transport system, permease component [Carbohydrate transport and ...
 125-419 2.26e-18

ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 443357 [Multi-domain]  Cd Length: 316  Bit Score: 85.14  E-value: 2.26e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 125 YLLTTPAyilMVFTIVF---PvLVTLLMAFTNYD----FAHIPpamlldWIGFKNFTsmFFLSSYRAtfnavfgWTVIW- 196
Cdd:COG4209   30 YLMLLPG---LIYLLIFsylP-MYGIVIAFKDYNpfkgIFGSP------WVGLKNFK--FLFSSPDF-------WRVLRn 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 197 TVCATTLQIIIG----IATAVIANQ-NFIKGKRFFGVIFLLP----WAIpafVSIMsFSNIFNDSAGAINvQVIGLWntl 267
Cdd:COG4209   91 TLLISLLKLVFGfplpIILALLLNElRSKRFKKTVQTISYLPhflsWVV---VAGI-VYQFLSPDTGLVN-QLLRAL--- 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 268 vpfaHIAPIHWMTDTFWTKVAIIMIQGWLGFPY---IYVM-ITGIlqaiPEDLYEAATLDGATVMQKFNKITLPTIfaia 343
Cdd:COG4209  163 ----GGEPINFLTEPKYFRPIYVFSGIWKEAGWgsiIYLAaITGI----DPELYEAAAIDGAGRWQQIWHITLPGI---- 230

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 344 APIFVTQYTFN----FN-NFSMIYLFNQggpgdvGANAGGTDILISWIYKLTTGTSpQYSLAAAVTLIISvlVIGISLIV 418
Cdd:COG4209  231 RPTIVILLILNigniLNvGFEQIYLLYN------PLNYSTSDVIDTYVYRIGLQNG-DYSYATAVGLFKS--VVGLILVL 301


                 .
gi 633897531 419 F 419
Cdd:COG4209  302 I 302
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
125-419 3.53e-15

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 77.51  E-value: 3.53e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 125 YLLTTPAYILMVFTIVFPVLVTLLMAFTNydfahippamlldwiGFKNFTSMFFLSSYRAtfnaVFGWTVIWTVCATTLQ 204
Cdd:COG1178   10 RLLLLLLALLLALLVLLPLLALLLRAFTD---------------GLANFWALLSDPYLWR----ALGNTLLLALLVTLLS 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 205 IIIGIATAVIANQNFIKGKRFFGVIFLLPWAIPAFVSIMSFSNIFNDSagainvqviGLWNTLVpfahIAPIHWMTDTFW 284
Cdd:COG1178   71 LLLGVPLAWLLARTDFPGRRLLRWLLLLPLALPPYVVALAWIALFGPN---------GLLNTLL----RALFGLEPPDIY 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 285 TKVAIIMIQGWLGFPYIYVMITGILQAIPEDLYEAATLDGATVMQKFNKITLP----TIFAIAAPIFVtqytFNFNNFSM 360
Cdd:COG1178  138 GLGGIILVLVLFNYPYVYLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPllrpAIAAGALLVFL----LCLADFGT 213

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 633897531 361 IYLFnqggpgdvganAGGTDILISWIYKLTTGtspQYSLAAAVTLIISVLVIGISLIVF 419
Cdd:COG1178  214 PLVL-----------GGGYTTLTTAIYQAWLG---DFDLGAAAALALVLLLLVLLLLLL 258
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 133-418 2.81e-11

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 63.96  E-value: 2.81e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 133 ILMVFTIVFPVLVTLLMAF-TNYDFAHIPPAMLLDWIGFKNFTSMFFLSSY-RATFNavfgwTVIWTVCATTLQIIIGIA 210
Cdd:COG0395   22 ILLALLFLFPLYWMVVTSFkPPAEIFSGPPSLLPSEFTLENYRAAFTDGPFgRYLLN-----SLIVAVVSTVLSLLLSSL 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 211 TA-VIANQNFiKGKRFFGVIFLLPWAIPAFVSIMSFSNIFNDsagainvqvIGLWNTLVPfahiapihwmtdtfwtkVAI 289
Cdd:COG0395   97 AAyALARFRF-RGRKLLFLLILATLMIPGQVLLIPLYLLFRQ---------LGLLNTYWG-----------------LIL 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 290 IMIQGWLGFpYIYVMiTGILQAIPEDLYEAATLDGATVMQKFNKITLPtifaIAAPIFVTQYTFNF----NNF--SMIYL 363
Cdd:COG0395  150 PYLAFGLPF-GIFLL-RQFFRSIPRELEEAARIDGASEFRIFWRIVLP----LSKPALATVAIFTFigawNDFlwPLILL 223

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 633897531 364 fnqggpgdvgaNAGGTDILISWIYKLTTGTSPQYSLAAAVTLIISVLVIGISLIV 418
Cdd:COG0395  224 -----------TSPDLRTLPVGLASFQGQYGTDWGLLMAAAVIATLPVLILFLFL 267
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 125-422 6.04e-11

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 62.44  E-value: 6.04e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 125 YLLTTPAYILMVFtIVFPVLVTLLMAFTNYDFAHIPPAMLldwiGFKNFTSMFflssYRATFNAVFGWTVIWTVCATTLQ 204
Cdd:COG1177    7 LLLRLFLALVLLF-LYLPILVLVLYSFNDSWFLTFPPEGF----TLRWYAELF----SDPRLLDALLNSLLIALLSTLLA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 205 IIIGIATAVIANQNFIKGKRFFGVIFLLPWAIPAFVSIMSFSNIFNDsagainvqvIGLwntlvpfahiapihwmTDTFW 284
Cdd:COG1177   78 TVLGTPAALALARYRFRGRRLLLALLLLPLVVPGIVLGVALLLLFSA---------LGL----------------SGGLW 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 285 TkvaIIMIQGWLGFPYIYVMITGILQAIPEDLYEAATLDGATVMQKFNKITLPTIFA--IAAPIFVtqYTFNFNNFSMIY 362
Cdd:COG1177  133 G---LILAHVVFTLPFVVLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPgiLAGALLA--FTLSFDEFVITL 207

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 633897531 363 LFnqGGPgdvganagGTDILISWIY-KLTTGTSPQYSLAAAVTLIISVLVIGISLIVFKKT 422
Cdd:COG1177  208 FL--AGP--------GVTTLPVYIYsMIRRGISPEINALSTLLILLSLLLLLLAERLRRRG 258
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 190-412 8.40e-10

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 58.06  E-value: 8.40e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 190 FGWTVIWTVCATTLQIIIGIATAVIANQNFIKGKRFFGVIFLLPWAIPAFVSIMSFSNIFNDSagainvqviglwntlvp 269
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVL----------------- 63

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 270 fahiapIHWMTDTFWTKVAIIMIQGWLgFPYIYVMITGILQAIPEDLYEAATLDGATVMQKFNKITLPTIFAIAAPIFVT 349
Cdd:cd06261   64 ------LGWGILPGLGLPALILALLLI-APFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVL 136

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 633897531 350 QYTFNFNNFSMIYLFNQGGPGdvganaggtdILISWIYKLTTGTSPQYSLAAAVTLIISVLVI 412
Cdd:cd06261  137 AFARALGEFALVSFLGGGEAP----------GPGTGLLLIFAILFPGDLGVAAAVALILLLLS 189
PRK10561 PRK10561
sn-glycerol-3-phosphate ABC transporter permease UgpA;
126-420 1.71e-08

sn-glycerol-3-phosphate ABC transporter permease UgpA;


Pssm-ID: 182550 [Multi-domain]  Cd Length: 280  Bit Score: 55.60  E-value: 1.71e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 126 LLTTPAYILMVFTIVFPVLVTLLMAFTNYDfahiPPAMLLDWIGFKNFTSMFFLSSYRATFNAvfgwTVIWTVCATTLQI 205
Cdd:PRK10561   1 LLVAPQLIITVIFFIWPAGEALWYSLQSVD----PFGFSSQFVGLDNFVALFHDSYYLDSFWT----TIKFSTLVTVSGL 72

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 206 IIGIATAVIANQnFIKGKRFFGVIFLLPWAIPAFVSIMSFSNIFNDSAGAINVQVIGL---WNtlvpfahiapihWMTDT 282
Cdd:PRK10561  73 LVSLFFAALVDY-VVRGSRFYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLAEFgydWN------------HAQNS 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 283 FWTKVAIIMIQGWLGFPYIYVMITGILQAIPEDLYEAATLDGATVMQKFNKITLPTIFAIAAPIFVTQ--YTFnFNNFSM 360
Cdd:PRK10561 140 GQAMFLVVFASVWKQISYNFLFFFAALQSIPRSLVEAAAIDGAGPIRRFFKLALPLIAPVSFFLLVVNlvYAF-FDTFPV 218

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 361 IYLFNQGGPgdvganAGGTDILISWIYKlTTGTSPQYSLAAAVTLIISVLVIGISLIVFK 420
Cdd:PRK10561 219 IDAATSGGP------VQATTTLIYKIYR-EGFTGLDLSSSAAQSVVLMFLVIVLTVVQFR 271
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
77-421 3.01e-08

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 55.55  E-value: 3.01e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531  77 ILLTIVFIVFYIANLYDAKHVAQLINnGKKVSHTFKELGaslvdgGFAYLLTTPAYILMVFTIVFPVLVTLLMAFTnydf 156
Cdd:COG1178  247 VLLLLVLLLLLLERRLRRRRRYATVG-GRARRPRRVKLG------RWRWLALALCLLLVLLGLLLPLLALLLWSLT---- 315

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 157 ahippamlldwigfKNFTSMFFLSSYRATFNAVFGWTVIWT-----VCATTLQIIIGIATAVIANQNFIKGKRFFGVIFL 231
Cdd:COG1178  316 --------------KALDDNLTLDNYRFVLLDPSLLRALLNslllaLLAALLAVLLALLLAYLVRRRRGRLARLLDRLAM 381

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 232 LPWAIPAFVsimsfsnifndsAGainvqvIGLwntLVPFAHIAPIhWMTDTFWtkvAIIMIQGWLGFPYIYVMITGILQA 311
Cdd:COG1178  382 LPYAVPGIV------------LG------LGL---LLLFNRPLPL-LLYGTLA---ILVLAYVVRFLPFALRSLEAALAQ 436

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 312 IPEDLYEAATLDGATVMQKFNKITLP----TIFAIAAPIFVTqytfnfnnfSMiylfnqggpGDVGANA----GGTDILI 383
Cdd:COG1178  437 IDPSLEEAARSLGASPLRTLRRVTLPllrpGLLAAALLVFVT---------SM---------KELSATLllrpPGFETLA 498

                        330       340       350
                 ....*....|....*....|....*....|....*...
gi 633897531 384 SWIYKLTtgTSPQYSLAAAVTLIIsVLVIGISLIVFKK 421
Cdd:COG1178  499 VLIYQLA--SSGRYGEAAALALLL-VLVSLLPVLLLER 533
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 273-412 4.76e-08

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 52.69  E-value: 4.76e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531  273 IAPIHWMTDTFWTKVAIIMIQGWLGFPYIYVMITGILQAIPEDLYEAATLDGATVMQKFNKITLPTIFAIAAPIFVTQYT 352
Cdd:pfam00528  39 LVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFG 118

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531  353 FNFNNFSMIYLFNQGGPgdvganAGGTDILISWIYKLTTGTSPQYSLAAAVTLIISVLVI 412
Cdd:pfam00528 119 GALGGAVLLEFLGSWPG------LGLLLIEAILGYDYPEIQGPVLAAALILLLLNLLVDI 172
MalG COG3833
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and ...
 133-355 7.60e-08

ABC-type maltose transport system, permease component MalG [Carbohydrate transport and metabolism];


Pssm-ID: 443045 [Multi-domain]  Cd Length: 282  Bit Score: 53.62  E-value: 7.60e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 133 ILMVFTIVFPVLVTLLMAFTNYDFAhIPPAMLLDWIGFKNFTSMFFLSSY-RATFNavfgwTVIWTVCATTLQIIIGIAT 211
Cdd:COG3833   23 IILAIIALFPILWVVSASFNPGGSL-YSSSLIPENFTLENYKKLFTETPFlRWFLN-----SLIVAVVTAIISVFLAALA 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 212 A-VIANQNFiKGKRFFGVIFLLPWAIPAFVSIMSFSNIFNDsagainvqvIGLWNTlvpfaHIAPIhwmtdtfwtkvaII 290
Cdd:COG3833   97 AyAFSRFRF-KGRKAGLLALLLLQMFPAFLALVALYLLLSA---------LGLLNT-----LLGLI------------LV 149

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 633897531 291 MIQGWLGFpYIYVMiTGILQAIPEDLYEAATLDGATVMQKFNKITLPtifaIAAPIFVTQYTFNF 355
Cdd:COG3833  150 YLGGAIPF-NTWLM-KGYFDTIPKELDEAAKIDGASHFQIFFRIILP----LAKPILAVVALLSF 208
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 133-425 3.51e-07

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 52.38  E-value: 3.51e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531  133 ILMVFTIVFPVLVTLLMAFTNYDFahippamllDWIGFKNFTSMFFLSSyratFNAVFGWTVIWTVCATTLQIIIGIATA 212
Cdd:TIGR03262  12 LALLLFLLLPLLALLTKSVYDSDG---------DFIGLANFAEYFATPG----LLQSLGNSLTVSAIVTAIVVPLAFAFA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531  213 VIANQNFIKGKRFFGVIFLLPWAIPAFVSIMSFSNIFndsagainvqviGLWNTLVPFAHIAPIhwmtdtfWTKVAIIMI 292
Cdd:TIGR03262  79 YALTRSRIPGKGAFRLVALLPLLAPSLLPAISLIYLF------------GNQGLLKGLLGGFSI-------YGFWGIVIG 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531  293 QGWLGFPYIYVMITGILQAIPEDLYEAATLDGATVMQKFNKITLPTI-FAIAAPIFVTqYTFNFNNFsmiylfnqGGPGD 371
Cdd:TIGR03262 140 EVFYTFPHALMILVTALSLADGRLYEAARAMGASPWRTFFTVTLPGAkYGLISAAFVV-FTLVITDF--------GVPKV 210

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 633897531  372 VGanaGGTDILISWIYKLTTGTSpQYSLAAAVTLII---SVLVIGISLIVFKKTHAF 425
Cdd:TIGR03262 211 IG---GDYNVLATDIYKQVIGQQ-NFPMGAVVGVLLllpALLAFGIDRAIQRRQRAQ 263
cysT CHL00187
sulfate transport protein; Provisional
 135-355 4.13e-06

sulfate transport protein; Provisional


Pssm-ID: 214388 [Multi-domain]  Cd Length: 237  Bit Score: 47.70  E-value: 4.13e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 135 MVFTIVFPVLVTLLMAFTNydFAHIPPAMLLDWIGFKNFTSMFFLSSYRATFNAVFGWTVIWtvcattlqiiigiataVI 214
Cdd:CHL00187  21 IIFLLVLPILALLIKASQQ--PWSDFLQKATEPIALSAYSLTLSMALIAALINGFFGLLIAW----------------VL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 215 ANQNFiKGKRFFGVIFLLPWAIPAFVSIMSFSNIFNDSAgainvqviglwntlvPFAHIAPIHWMTDTFwTKVAIIMIQG 294
Cdd:CHL00187  83 VRYNF-PGKRLLDAAVDLPFALPTSVAGLTLATVYGDNG---------------WIGHLLSHLGIQIVF-TKLGVLLAMI 145

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 633897531 295 WLGFPYIYVMITGILQAIPEDLYEAATLDGATVMQKFNKITLPTIFaiaaPIFVTQYTFNF 355
Cdd:CHL00187 146 FVSFPFVVRTIQPVLQEIEKELEEAAWSLGASPWQTFWKVIFPPLI----PALLTGLALTF 202
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 116-340 2.54e-05

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 45.51  E-value: 2.54e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 116 ASLVDGGFAYLLTTPAYILMVFtIVFPVLVTLLMAFTnydfahippamlLDWIGF-KNFTSMFFLSSYRATFNAvfgwtv 194
Cdd:COG0555    2 SRRVLPGFGLTLGLTLLYLSLI-VLLPLAALVLKAAG------------LGWAEFwAVLTSPRVLAALKLSLGT------ 62

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 633897531 195 iwTVCATTLQIIIGIATA-VIANQNFiKGKRFFGVIFLLPWAIPAFVSIMSFSNIFNdSAGAINvqviglwntlvpfAHI 273
Cdd:COG0555   63 --ALIAALINLVFGLPLAwVLVRYRF-PGKRLVDALVDLPFALPTAVAGIALLLLFG-PNGWLG-------------QLL 125

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 633897531 274 APIHWmtDTFWTKVAIIMIQGWLGFPYIYVMITGILQAIPEDLYEAATLDGATVMQKFNKITLPTIF 340
Cdd:COG0555  126 APLGI--KVAFTPLGIVLAQTFVSLPFVVRTVQPVLEELDPELEEAAATLGASRWQTFRRVILPLLL 190
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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