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Conserved domains on  [gi|15027131|emb|CAC44781|]
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RecA protein, partial [Lacticaseibacillus rhamnosus]

Protein Classification

DNA recombination/repair protein RecA( domain architecture ID 1000164)

DNA recombination/repair protein RecA catalyzes an ATP-dependent DNA strand-exchange reaction, which is a critical step in the repair of DNA double-strand breaks by homologous recombination

Gene Ontology:  GO:0005524|GO:0006310|GO:0006281
PubMed:  31100988

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
recA super family cl35814
recombinase A; Provisional
 1-92 8.62e-63

recombinase A; Provisional


The actual alignment was detected with superfamily member PRK09354:

Pssm-ID: 236476 [Multi-domain]  Cd Length: 349  Bit Score: 193.47  E-value: 8.62e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15027131    1 MDPKYAAALGVNIDELLLSQPDTGEQGLEIADELVASGAIDILVVDSVAALVPRAEIEGDMGDAHVGLQARLMSQALRKL 80
Cdd:PRK09354 100 LDPVYAKKLGVDIDNLLVSQPDTGEQALEIADTLVRSGAVDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKL 179

                         90
                 ....*....|..
gi 15027131   81 SGAINKTKTIAL 92
Cdd:PRK09354 180 TGNISKSNTTVI 191
 
Name Accession Description Interval E-value
recA PRK09354
recombinase A; Provisional
 1-92 8.62e-63

recombinase A; Provisional


Pssm-ID: 236476 [Multi-domain]  Cd Length: 349  Bit Score: 193.47  E-value: 8.62e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15027131    1 MDPKYAAALGVNIDELLLSQPDTGEQGLEIADELVASGAIDILVVDSVAALVPRAEIEGDMGDAHVGLQARLMSQALRKL 80
Cdd:PRK09354 100 LDPVYAKKLGVDIDNLLVSQPDTGEQALEIADTLVRSGAVDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKL 179

                         90
                 ....*....|..
gi 15027131   81 SGAINKTKTIAL 92
Cdd:PRK09354 180 TGNISKSNTTVI 191
RecA COG0468
RecA/RadA recombinase [Replication, recombination and repair];
1-92 4.37e-61

RecA/RadA recombinase [Replication, recombination and repair];


Pssm-ID: 440236 [Multi-domain]  Cd Length: 351  Bit Score: 188.84  E-value: 4.37e-61
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15027131   1 MDPKYAAALGVNIDELLLSQPDTGEQGLEIADELVASGAIDILVVDSVAALVPRAEIEGDMGDAHVGLQARLMSQALRKL 80
Cdd:COG0468 103 LDPEYAKKLGVDIDNLLVSQPDTGEQALEIAETLVRSGAVDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKL 182

                        90
                ....*....|..
gi 15027131  81 SGAINKTKTIAL 92
Cdd:COG0468 183 TGAISKSNTTVI 194
RecA cd00983
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ...
 1-92 5.08e-57

recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange.


Pssm-ID: 410863 [Multi-domain]  Cd Length: 235  Bit Score: 175.05  E-value: 5.08e-57
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15027131   1 MDPKYAAALGVNIDELLLSQPDTGEQGLEIADELVASGAIDILVVDSVAALVPRAEIEGDMGDAHVGLQARLMSQALRKL 80
Cdd:cd00983  64 LDPEYAKKLGVDIDNLLVSQPDTGEQALEIADTLIRSGAVDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKL 143

                        90
                ....*....|..
gi 15027131  81 SGAINKTKTIAL 92
Cdd:cd00983 144 TGSLSKSKTTVI 155
RecA pfam00154
recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA ...
 1-92 5.97e-57

recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA repair systems. RecA protein catalyzes an ATP-dependent DNA strand-exchange reaction that is the central step in the repair of dsDNA breaks by homologous recombination.


Pssm-ID: 425488 [Multi-domain]  Cd Length: 262  Bit Score: 175.66  E-value: 5.97e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15027131     1 MDPKYAAALGVNIDELLLSQPDTGEQGLEIADELVASGAIDILVVDSVAALVPRAEIEGDMGDAHVGLQARLMSQALRKL 80
Cdd:pfam00154  92 LDPVYAKKLGVDIDNLLVSQPDTGEQALEIADMLVRSGAIDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKL 171

                          90
                  ....*....|..
gi 15027131    81 SGAINKTKTIAL 92
Cdd:pfam00154 172 TGSISKSNTTVI 183
tigrfam_recA TIGR02012
protein RecA; This model describes orthologs of the recA protein. RecA promotes hybridization ...
 1-92 3.31e-56

protein RecA; This model describes orthologs of the recA protein. RecA promotes hybridization of homolgous regions of DNA. A segment of ssDNA can be hybridized to another ssDNA region, or to a dsDNA region. ATP is hydrolyzed in the process. Part of the SOS respones, it is regulated by LexA via autocatalytic cleavage. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 162659 [Multi-domain]  Cd Length: 321  Bit Score: 175.64  E-value: 3.31e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15027131     1 MDPKYAAALGVNIDELLLSQPDTGEQGLEIADELVASGAIDILVVDSVAALVPRAEIEGDMGDAHVGLQARLMSQALRKL 80
Cdd:TIGR02012  95 LDPVYARKLGVDIDNLLVSQPDTGEQALEIAETLVRSGAVDIIVVDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKL 174

                          90
                  ....*....|..
gi 15027131    81 SGAINKTKTIAL 92
Cdd:TIGR02012 175 TGALSKSNTTAI 186
 
Name Accession Description Interval E-value
recA PRK09354
recombinase A; Provisional
 1-92 8.62e-63

recombinase A; Provisional


Pssm-ID: 236476 [Multi-domain]  Cd Length: 349  Bit Score: 193.47  E-value: 8.62e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15027131    1 MDPKYAAALGVNIDELLLSQPDTGEQGLEIADELVASGAIDILVVDSVAALVPRAEIEGDMGDAHVGLQARLMSQALRKL 80
Cdd:PRK09354 100 LDPVYAKKLGVDIDNLLVSQPDTGEQALEIADTLVRSGAVDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKL 179

                         90
                 ....*....|..
gi 15027131   81 SGAINKTKTIAL 92
Cdd:PRK09354 180 TGNISKSNTTVI 191
RecA COG0468
RecA/RadA recombinase [Replication, recombination and repair];
1-92 4.37e-61

RecA/RadA recombinase [Replication, recombination and repair];


Pssm-ID: 440236 [Multi-domain]  Cd Length: 351  Bit Score: 188.84  E-value: 4.37e-61
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15027131   1 MDPKYAAALGVNIDELLLSQPDTGEQGLEIADELVASGAIDILVVDSVAALVPRAEIEGDMGDAHVGLQARLMSQALRKL 80
Cdd:COG0468 103 LDPEYAKKLGVDIDNLLVSQPDTGEQALEIAETLVRSGAVDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKL 182

                        90
                ....*....|..
gi 15027131  81 SGAINKTKTIAL 92
Cdd:COG0468 183 TGAISKSNTTVI 194
RecA cd00983
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ...
 1-92 5.08e-57

recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange.


Pssm-ID: 410863 [Multi-domain]  Cd Length: 235  Bit Score: 175.05  E-value: 5.08e-57
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15027131   1 MDPKYAAALGVNIDELLLSQPDTGEQGLEIADELVASGAIDILVVDSVAALVPRAEIEGDMGDAHVGLQARLMSQALRKL 80
Cdd:cd00983  64 LDPEYAKKLGVDIDNLLVSQPDTGEQALEIADTLIRSGAVDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKL 143

                        90
                ....*....|..
gi 15027131  81 SGAINKTKTIAL 92
Cdd:cd00983 144 TGSLSKSKTTVI 155
RecA pfam00154
recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA ...
 1-92 5.97e-57

recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA repair systems. RecA protein catalyzes an ATP-dependent DNA strand-exchange reaction that is the central step in the repair of dsDNA breaks by homologous recombination.


Pssm-ID: 425488 [Multi-domain]  Cd Length: 262  Bit Score: 175.66  E-value: 5.97e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15027131     1 MDPKYAAALGVNIDELLLSQPDTGEQGLEIADELVASGAIDILVVDSVAALVPRAEIEGDMGDAHVGLQARLMSQALRKL 80
Cdd:pfam00154  92 LDPVYAKKLGVDIDNLLVSQPDTGEQALEIADMLVRSGAIDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKL 171

                          90
                  ....*....|..
gi 15027131    81 SGAINKTKTIAL 92
Cdd:pfam00154 172 TGSISKSNTTVI 183
tigrfam_recA TIGR02012
protein RecA; This model describes orthologs of the recA protein. RecA promotes hybridization ...
 1-92 3.31e-56

protein RecA; This model describes orthologs of the recA protein. RecA promotes hybridization of homolgous regions of DNA. A segment of ssDNA can be hybridized to another ssDNA region, or to a dsDNA region. ATP is hydrolyzed in the process. Part of the SOS respones, it is regulated by LexA via autocatalytic cleavage. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 162659 [Multi-domain]  Cd Length: 321  Bit Score: 175.64  E-value: 3.31e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15027131     1 MDPKYAAALGVNIDELLLSQPDTGEQGLEIADELVASGAIDILVVDSVAALVPRAEIEGDMGDAHVGLQARLMSQALRKL 80
Cdd:TIGR02012  95 LDPVYARKLGVDIDNLLVSQPDTGEQALEIAETLVRSGAVDIIVVDSVAALVPKAEIEGEMGDSHVGLQARLMSQALRKL 174

                          90
                  ....*....|..
gi 15027131    81 SGAINKTKTIAL 92
Cdd:TIGR02012 175 TGALSKSNTTAI 186
recA PRK09519
intein-containing recombinase RecA;
1-92 1.85e-41

intein-containing recombinase RecA;


Pssm-ID: 77219 [Multi-domain]  Cd Length: 790  Bit Score: 143.70  E-value: 1.85e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15027131    1 MDPKYAAALGVNIDELLLSQPDTGEQGLEIADELVASGAIDILVVDSVAALVPRAEIEGDMGDAHVGLQARLMSQALRKL 80
Cdd:PRK09519 100 LDPDYAKKLGVDTDSLLVSQPDTGEQALEIADMLIRSGALDIVVIDSVAALVPRAELEGEMGDSHVGLQARLMSQALRKM 179

                         90
                 ....*....|..
gi 15027131   81 SGAINKTKTIAL 92
Cdd:PRK09519 180 TGALNNSGTTAI 191
RecA-like cd01393
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ...
 9-86 3.96e-12

RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange. While prokaryotes have a single RecA protein, eukaryotes have multiple RecA homologs such as Rad51, DMC1 and Rad55/57. Archaea have the RecA-like homologs RadA and RadB.


Pssm-ID: 410881 [Multi-domain]  Cd Length: 185  Bit Score: 58.52  E-value: 3.96e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15027131   9 LGVNIDELLLSQPDTGEQGLEIADELVASGA----IDILVVDSVAALVPRAEIEGDMGDAHVGLQARLMSQALRKLSGAI 84
Cdd:cd01393  60 LAEALSRLLYFRPPDTLAHLLALDSLPESLFpppnTSLVVVDSVSALFRKAFPRGGDGDSSSSLRARLLSQLARALQKLA 139


                ..
gi 15027131  85 NK 86
Cdd:cd01393 140 AQ 141
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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