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Conserved domains on  [gi|2091646230|gb|UAJ23498|]
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RecA, partial [Lactiplantibacillus plantarum]

Protein Classification

DNA recombination/repair protein RecA( domain architecture ID 1000164)

DNA recombination/repair protein RecA catalyzes an ATP-dependent DNA strand-exchange reaction, which is a critical step in the repair of DNA double-strand breaks by homologous recombination

Gene Ontology:  GO:0005524|GO:0006310|GO:0006281
PubMed:  31100988

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
recA super family cl35814
recombinase A; Provisional
 1-90 5.87e-67

recombinase A; Provisional


The actual alignment was detected with superfamily member PRK09354:

Pssm-ID: 236476 [Multi-domain]  Cd Length: 349  Bit Score: 203.87  E-value: 5.87e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2091646230   1 YIDAENALDPVYAEHLGVNIDDLLLSQPDTGEQGLEIADALVSSGAVDILVVDSVAALVPRAEIEGEMGDAHVGLQARLM 80
Cdd:PRK09354   93 FIDAEHALDPVYAKKLGVDIDNLLVSQPDTGEQALEIADTLVRSGAVDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLM 172

                          90
                  ....*....|
gi 2091646230  81 SQALRKLSGT 90
Cdd:PRK09354  173 SQALRKLTGN 182
 
Name Accession Description Interval E-value
recA PRK09354
recombinase A; Provisional
 1-90 5.87e-67

recombinase A; Provisional


Pssm-ID: 236476 [Multi-domain]  Cd Length: 349  Bit Score: 203.87  E-value: 5.87e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2091646230   1 YIDAENALDPVYAEHLGVNIDDLLLSQPDTGEQGLEIADALVSSGAVDILVVDSVAALVPRAEIEGEMGDAHVGLQARLM 80
Cdd:PRK09354   93 FIDAEHALDPVYAKKLGVDIDNLLVSQPDTGEQALEIADTLVRSGAVDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLM 172

                          90
                  ....*....|
gi 2091646230  81 SQALRKLSGT 90
Cdd:PRK09354  173 SQALRKLTGN 182
RecA COG0468
RecA/RadA recombinase [Replication, recombination and repair];
1-90 3.81e-65

RecA/RadA recombinase [Replication, recombination and repair];


Pssm-ID: 440236 [Multi-domain]  Cd Length: 351  Bit Score: 199.24  E-value: 3.81e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2091646230   1 YIDAENALDPVYAEHLGVNIDDLLLSQPDTGEQGLEIADALVSSGAVDILVVDSVAALVPRAEIEGEMGDAHVGLQARLM 80
Cdd:COG0468    96 FIDAEHALDPEYAKKLGVDIDNLLVSQPDTGEQALEIAETLVRSGAVDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLM 175

                          90
                  ....*....|
gi 2091646230  81 SQALRKLSGT 90
Cdd:COG0468   176 SQALRKLTGA 185
RecA cd00983
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ...
 1-90 4.98e-61

recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange.


Pssm-ID: 410863 [Multi-domain]  Cd Length: 235  Bit Score: 185.07  E-value: 4.98e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2091646230   1 YIDAENALDPVYAEHLGVNIDDLLLSQPDTGEQGLEIADALVSSGAVDILVVDSVAALVPRAEIEGEMGDAHVGLQARLM 80
Cdd:cd00983    57 FIDAEHALDPEYAKKLGVDIDNLLVSQPDTGEQALEIADTLIRSGAVDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLM 136

                          90
                  ....*....|
gi 2091646230  81 SQALRKLSGT 90
Cdd:cd00983   137 SQALRKLTGS 146
tigrfam_recA TIGR02012
protein RecA; This model describes orthologs of the recA protein. RecA promotes hybridization ...
 1-90 8.55e-59

protein RecA; This model describes orthologs of the recA protein. RecA promotes hybridization of homolgous regions of DNA. A segment of ssDNA can be hybridized to another ssDNA region, or to a dsDNA region. ATP is hydrolyzed in the process. Part of the SOS respones, it is regulated by LexA via autocatalytic cleavage. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 162659 [Multi-domain]  Cd Length: 321  Bit Score: 182.18  E-value: 8.55e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2091646230   1 YIDAENALDPVYAEHLGVNIDDLLLSQPDTGEQGLEIADALVSSGAVDILVVDSVAALVPRAEIEGEMGDAHVGLQARLM 80
Cdd:TIGR02012  88 FIDAEHALDPVYARKLGVDIDNLLVSQPDTGEQALEIAETLVRSGAVDIIVVDSVAALVPKAEIEGEMGDSHVGLQARLM 167

                          90
                  ....*....|
gi 2091646230  81 SQALRKLSGT 90
Cdd:TIGR02012 168 SQALRKLTGA 177
RecA pfam00154
recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA ...
 1-89 1.04e-58

recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA repair systems. RecA protein catalyzes an ATP-dependent DNA strand-exchange reaction that is the central step in the repair of dsDNA breaks by homologous recombination.


Pssm-ID: 425488 [Multi-domain]  Cd Length: 262  Bit Score: 180.29  E-value: 1.04e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2091646230   1 YIDAENALDPVYAEHLGVNIDDLLLSQPDTGEQGLEIADALVSSGAVDILVVDSVAALVPRAEIEGEMGDAHVGLQARLM 80
Cdd:pfam00154  85 FIDAEHALDPVYAKKLGVDIDNLLVSQPDTGEQALEIADMLVRSGAIDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLM 164


                  ....*....
gi 2091646230  81 SQALRKLSG 89
Cdd:pfam00154 165 SQALRKLTG 173
 
Name Accession Description Interval E-value
recA PRK09354
recombinase A; Provisional
 1-90 5.87e-67

recombinase A; Provisional


Pssm-ID: 236476 [Multi-domain]  Cd Length: 349  Bit Score: 203.87  E-value: 5.87e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2091646230   1 YIDAENALDPVYAEHLGVNIDDLLLSQPDTGEQGLEIADALVSSGAVDILVVDSVAALVPRAEIEGEMGDAHVGLQARLM 80
Cdd:PRK09354   93 FIDAEHALDPVYAKKLGVDIDNLLVSQPDTGEQALEIADTLVRSGAVDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLM 172

                          90
                  ....*....|
gi 2091646230  81 SQALRKLSGT 90
Cdd:PRK09354  173 SQALRKLTGN 182
RecA COG0468
RecA/RadA recombinase [Replication, recombination and repair];
1-90 3.81e-65

RecA/RadA recombinase [Replication, recombination and repair];


Pssm-ID: 440236 [Multi-domain]  Cd Length: 351  Bit Score: 199.24  E-value: 3.81e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2091646230   1 YIDAENALDPVYAEHLGVNIDDLLLSQPDTGEQGLEIADALVSSGAVDILVVDSVAALVPRAEIEGEMGDAHVGLQARLM 80
Cdd:COG0468    96 FIDAEHALDPEYAKKLGVDIDNLLVSQPDTGEQALEIAETLVRSGAVDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLM 175

                          90
                  ....*....|
gi 2091646230  81 SQALRKLSGT 90
Cdd:COG0468   176 SQALRKLTGA 185
RecA cd00983
recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ...
 1-90 4.98e-61

recombinase A; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange.


Pssm-ID: 410863 [Multi-domain]  Cd Length: 235  Bit Score: 185.07  E-value: 4.98e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2091646230   1 YIDAENALDPVYAEHLGVNIDDLLLSQPDTGEQGLEIADALVSSGAVDILVVDSVAALVPRAEIEGEMGDAHVGLQARLM 80
Cdd:cd00983    57 FIDAEHALDPEYAKKLGVDIDNLLVSQPDTGEQALEIADTLIRSGAVDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLM 136

                          90
                  ....*....|
gi 2091646230  81 SQALRKLSGT 90
Cdd:cd00983   137 SQALRKLTGS 146
tigrfam_recA TIGR02012
protein RecA; This model describes orthologs of the recA protein. RecA promotes hybridization ...
 1-90 8.55e-59

protein RecA; This model describes orthologs of the recA protein. RecA promotes hybridization of homolgous regions of DNA. A segment of ssDNA can be hybridized to another ssDNA region, or to a dsDNA region. ATP is hydrolyzed in the process. Part of the SOS respones, it is regulated by LexA via autocatalytic cleavage. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 162659 [Multi-domain]  Cd Length: 321  Bit Score: 182.18  E-value: 8.55e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2091646230   1 YIDAENALDPVYAEHLGVNIDDLLLSQPDTGEQGLEIADALVSSGAVDILVVDSVAALVPRAEIEGEMGDAHVGLQARLM 80
Cdd:TIGR02012  88 FIDAEHALDPVYARKLGVDIDNLLVSQPDTGEQALEIAETLVRSGAVDIIVVDSVAALVPKAEIEGEMGDSHVGLQARLM 167

                          90
                  ....*....|
gi 2091646230  81 SQALRKLSGT 90
Cdd:TIGR02012 168 SQALRKLTGA 177
RecA pfam00154
recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA ...
 1-89 1.04e-58

recA bacterial DNA recombination protein; RecA is a DNA-dependent ATPase and functions in DNA repair systems. RecA protein catalyzes an ATP-dependent DNA strand-exchange reaction that is the central step in the repair of dsDNA breaks by homologous recombination.


Pssm-ID: 425488 [Multi-domain]  Cd Length: 262  Bit Score: 180.29  E-value: 1.04e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2091646230   1 YIDAENALDPVYAEHLGVNIDDLLLSQPDTGEQGLEIADALVSSGAVDILVVDSVAALVPRAEIEGEMGDAHVGLQARLM 80
Cdd:pfam00154  85 FIDAEHALDPVYAKKLGVDIDNLLVSQPDTGEQALEIADMLVRSGAIDLIVVDSVAALVPKAEIEGEMGDSHVGLQARLM 164


                  ....*....
gi 2091646230  81 SQALRKLSG 89
Cdd:pfam00154 165 SQALRKLTG 173
recA PRK09519
intein-containing recombinase RecA;
1-89 2.41e-43

intein-containing recombinase RecA;


Pssm-ID: 77219 [Multi-domain]  Cd Length: 790  Bit Score: 149.09  E-value: 2.41e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2091646230   1 YIDAENALDPVYAEHLGVNIDDLLLSQPDTGEQGLEIADALVSSGAVDILVVDSVAALVPRAEIEGEMGDAHVGLQARLM 80
Cdd:PRK09519   93 FIDAEHALDPDYAKKLGVDTDSLLVSQPDTGEQALEIADMLIRSGALDIVVIDSVAALVPRAELEGEMGDSHVGLQARLM 172


                  ....*....
gi 2091646230  81 SQALRKLSG 89
Cdd:PRK09519  173 SQALRKMTG 181
RecA-like cd01393
RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA ...
 1-89 7.17e-18

RecA family; RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange. While prokaryotes have a single RecA protein, eukaryotes have multiple RecA homologs such as Rad51, DMC1 and Rad55/57. Archaea have the RecA-like homologs RadA and RadB.


Pssm-ID: 410881 [Multi-domain]  Cd Length: 185  Bit Score: 73.54  E-value: 7.17e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2091646230   1 YIDAENALDPVYA-----------EHLGVNIDDLLLSQPDTGEQGLEIADALV----SSGAVDILVVDSVAALVPRAEIE 65
Cdd:cd01393    34 WIDTEGAFPPSRLvqileaspsseLELAEALSRLLYFRPPDTLAHLLALDSLPeslfPPPNTSLVVVDSVSALFRKAFPR 113

                          90       100
                  ....*....|....*....|....
gi 2091646230  66 GEMGDAHVGLQARLMSQALRKLSG 89
Cdd:cd01393   114 GGDGDSSSSLRARLLSQLARALQK 137
Rad51 pfam08423
Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ...
 1-88 5.04e-03

Rad51; Rad51 is a DNA repair and recombination protein and is a homolog of the bacterial ATPase RecA protein.


Pssm-ID: 462471 [Multi-domain]  Cd Length: 255  Bit Score: 34.20  E-value: 5.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2091646230   1 YIDAENALDPV----YAEHLGVNIDDLLLSQP-------DTGEQGLEIADALVSSGAVDILVVDSVAALVpRAEIE--GE 67
Cdd:pfam08423  76 YIDTEGTFRPErlvaIAERYGLDPEDVLDNVAyaraynsEHQMQLLQQAAAMMSESRFALLIVDSATALY-RTDFSgrGE 154

                          90       100
                  ....*....|....*....|.
gi 2091646230  68 MGDAHVGLqARLMSqALRKLS 88
Cdd:pfam08423 155 LAERQQHL-AKFLR-TLQRLA 173
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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