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Conserved domains on  [gi|2221334101|ref|WP_244285228|]
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MULTISPECIES: FIVAR domain-containing protein, partial [Lactobacillus]

Protein Classification

FIVAR domain-containing protein( domain architecture ID 10540824)

FIVAR domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
FIVAR pfam07554
FIVAR domain; This domain is found in a wide variety of contexts, but mostly occurring in cell ...
26-91 4.86e-05

FIVAR domain; This domain is found in a wide variety of contexts, but mostly occurring in cell wall associated proteins. A lack of conserved catalytic residues suggests that it is a binding domain. From context, possible substrates are hyaluronate or fibronectin (personal obs: C Yeats). This is further evidenced by. Possibly the exact substrate is N-acetyl glucosamine. Finding it in the same protein as pfam05089 further supports this proposal. It is found in the C-terminal part of Swiss:O82833, which is removed during maturation. Some of the proteins it is found in are involved in methicillin resistance. The name FIVAR derives from Found In Various Architectures.


:

Pssm-ID: 400096 [Multi-domain]  Cd Length: 69  Bit Score: 38.07  E-value: 4.86e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2221334101 26 SALETAVNDQSDVQKTSAYYNASDDKKQAYDDAVSAGQTVLN---NDSATQSEVDSATTAINNAKSALD 91
Cdd:pfam07554  1 KALKTSINDKNATKTSSNYINADNDKKAAYNNAITAAKAILNktnNPNATQEEVNQALTKLNTAINALN 69
 
Name Accession Description Interval E-value
FIVAR pfam07554
FIVAR domain; This domain is found in a wide variety of contexts, but mostly occurring in cell ...
26-91 4.86e-05

FIVAR domain; This domain is found in a wide variety of contexts, but mostly occurring in cell wall associated proteins. A lack of conserved catalytic residues suggests that it is a binding domain. From context, possible substrates are hyaluronate or fibronectin (personal obs: C Yeats). This is further evidenced by. Possibly the exact substrate is N-acetyl glucosamine. Finding it in the same protein as pfam05089 further supports this proposal. It is found in the C-terminal part of Swiss:O82833, which is removed during maturation. Some of the proteins it is found in are involved in methicillin resistance. The name FIVAR derives from Found In Various Architectures.


Pssm-ID: 400096 [Multi-domain]  Cd Length: 69  Bit Score: 38.07  E-value: 4.86e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2221334101 26 SALETAVNDQSDVQKTSAYYNASDDKKQAYDDAVSAGQTVLN---NDSATQSEVDSATTAINNAKSALD 91
Cdd:pfam07554  1 KALKTSINDKNATKTSSNYINADNDKKAAYNNAITAAKAILNktnNPNATQEEVNQALTKLNTAINALN 69
 
Name Accession Description Interval E-value
FIVAR pfam07554
FIVAR domain; This domain is found in a wide variety of contexts, but mostly occurring in cell ...
26-91 4.86e-05

FIVAR domain; This domain is found in a wide variety of contexts, but mostly occurring in cell wall associated proteins. A lack of conserved catalytic residues suggests that it is a binding domain. From context, possible substrates are hyaluronate or fibronectin (personal obs: C Yeats). This is further evidenced by. Possibly the exact substrate is N-acetyl glucosamine. Finding it in the same protein as pfam05089 further supports this proposal. It is found in the C-terminal part of Swiss:O82833, which is removed during maturation. Some of the proteins it is found in are involved in methicillin resistance. The name FIVAR derives from Found In Various Architectures.


Pssm-ID: 400096 [Multi-domain]  Cd Length: 69  Bit Score: 38.07  E-value: 4.86e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2221334101 26 SALETAVNDQSDVQKTSAYYNASDDKKQAYDDAVSAGQTVLN---NDSATQSEVDSATTAINNAKSALD 91
Cdd:pfam07554  1 KALKTSINDKNATKTSSNYINADNDKKAAYNNAITAAKAILNktnNPNATQEEVNQALTKLNTAINALN 69
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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