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Conserved domains on  [gi|2485681954|ref|WP_278491967|]
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4Fe-4S binding protein [Methanococcus maripaludis]

Protein Classification

MtMvhB_like domain-containing protein( domain architecture ID 11586755)

MtMvhB_like domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 56-177 7.36e-22

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


:

Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 90.15  E-value: 7.36e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954  56 LVFNGSKCDLDGACAKACPVGIKKVDDRFPYSKG------HCVLCEKCVDICPAEIISLPGKAE---KPKKEIIIPQEpi 126
Cdd:cd10549     1 LKYDPEKCIGCGICVKACPTDAIELGPNGAIARGpeidedKCVFCGACVEVCPTGAIELTPEGKeyvPKEKEAEIDEE-- 78

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2485681954 127 avtkDCVACGVCVPECPVDAISIEDI--AVIDTDKCIYCTVCSQTCPWNAIFV 177
Cdd:cd10549    79 ----KCIGCGLCVKVCPVDAITLEDEleIVIDKEKCIGCGICAEVCPVNAIKL 127
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 125-247 7.66e-22

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


:

Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 90.15  E-value: 7.66e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 125 PIAVTKDCVACGVCVPECPVDAISIEDI------AVIDTDKCIYCTVCSQTCPWNAIFVaGKLPQKRQKTIKSFTVNEEE 198
Cdd:cd10549     1 LKYDPEKCIGCGICVKACPTDAIELGPNgaiargPEIDEDKCVFCGACVEVCPTGAIEL-TPEGKEYVPKEKEAEIDEEK 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 2485681954 199 CIGCEKCVEACPGSMIEYNGEALGVKLPEACPACGLCVESCPVEVISLE 247
Cdd:cd10549    80 CIGCGLCVKVCPVDAITLEDELEIVIDKEKCIGCGICAEVCPVNAIKLV 128
DMSOR_beta-like super family cl25360
Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta ...
 226-363 5.78e-17

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


The actual alignment was detected with superfamily member cd10549:

Pssm-ID: 355383 [Multi-domain]  Cd Length: 128  Bit Score: 76.67  E-value: 5.78e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 226 PEACPACGLCVESCPVEVISLEVEYASAKPVtdeglVWSEEKCAYCGPCAIKCPTGAIKVVNPKGLELPSRNKTEKANEf 305
Cdd:cd10549     5 PEKCIGCGICVKACPTDAIELGPNGAIARGP-----EIDEDKCVFCGACVEVCPTGAIELTPEGKEYVPKEKEAEIDEE- 78

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2485681954 306 aMCIRCGACAMKCPTGALKMgkmvhegKEYARVEFSPALCNECGECVDVCPQKTLELT 363
Cdd:cd10549    79 -KCIGCGLCVKVCPVDAITL-------EDELEIVIDKEKCIGCGICAEVCPVNAIKLV 128
NapH super family cl33844
Polyferredoxin NapH [Energy production and conversion];
4-49 4.49e-06

Polyferredoxin NapH [Energy production and conversion];


The actual alignment was detected with superfamily member COG0348:

Pssm-ID: 440117 [Multi-domain]  Cd Length: 263  Bit Score: 47.75  E-value: 4.49e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 2485681954   4 ISIQEDACLVCNACAKACPTEaIEIA----PFKTCIQCFSCATACPTGAL 49
Cdd:COG0348   205 VRYDRGDCIDCGLCVKVCPMG-IDIRkgeiNQSECINCGRCIDACPKDAI 253
ferrodoxin_EFR1 super family cl45674
EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...
 345-389 6.95e-03

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).


The actual alignment was detected with superfamily member NF038196:

Pssm-ID: 468407 [Multi-domain]  Cd Length: 243  Bit Score: 37.92  E-value: 6.95e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2485681954 345 CNECGECVDVCPQKTLELTgdDKMPL-KGYCVMCLKCIEAC--------NKTKK 389
Cdd:NF038196  187 CIGCGICAKVCPVNNIEME--DGKPVwGHNCTHCLACIHRCpkeaieygKKTKK 238
 
Name Accession Description Interval E-value
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 56-177 7.36e-22

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 90.15  E-value: 7.36e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954  56 LVFNGSKCDLDGACAKACPVGIKKVDDRFPYSKG------HCVLCEKCVDICPAEIISLPGKAE---KPKKEIIIPQEpi 126
Cdd:cd10549     1 LKYDPEKCIGCGICVKACPTDAIELGPNGAIARGpeidedKCVFCGACVEVCPTGAIELTPEGKeyvPKEKEAEIDEE-- 78

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2485681954 127 avtkDCVACGVCVPECPVDAISIEDI--AVIDTDKCIYCTVCSQTCPWNAIFV 177
Cdd:cd10549    79 ----KCIGCGLCVKVCPVDAITLEDEleIVIDKEKCIGCGICAEVCPVNAIKL 127
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 125-247 7.66e-22

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 90.15  E-value: 7.66e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 125 PIAVTKDCVACGVCVPECPVDAISIEDI------AVIDTDKCIYCTVCSQTCPWNAIFVaGKLPQKRQKTIKSFTVNEEE 198
Cdd:cd10549     1 LKYDPEKCIGCGICVKACPTDAIELGPNgaiargPEIDEDKCVFCGACVEVCPTGAIEL-TPEGKEYVPKEKEAEIDEEK 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 2485681954 199 CIGCEKCVEACPGSMIEYNGEALGVKLPEACPACGLCVESCPVEVISLE 247
Cdd:cd10549    80 CIGCGLCVKVCPVDAITLEDELEIVIDKEKCIGCGICAEVCPVNAIKLV 128
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 226-363 5.78e-17

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 76.67  E-value: 5.78e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 226 PEACPACGLCVESCPVEVISLEVEYASAKPVtdeglVWSEEKCAYCGPCAIKCPTGAIKVVNPKGLELPSRNKTEKANEf 305
Cdd:cd10549     5 PEKCIGCGICVKACPTDAIELGPNGAIARGP-----EIDEDKCVFCGACVEVCPTGAIELTPEGKEYVPKEKEAEIDEE- 78

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2485681954 306 aMCIRCGACAMKCPTGALKMgkmvhegKEYARVEFSPALCNECGECVDVCPQKTLELT 363
Cdd:cd10549    79 -KCIGCGLCVKVCPVDAITL-------EDELEIVIDKEKCIGCGICAEVCPVNAIKLV 128
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
125-175 3.57e-11

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 58.59  E-value: 3.57e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2485681954 125 PIAVTKDCVACGVCVPECPVDAISIED-IAVIDTDKCIYCTVCSQTCPWNAI 175
Cdd:COG2768     6 PYVDEEKCIGCGACVKVCPVGAISIEDgKAVIDPEKCIGCGACIEVCPVGAI 57
PRK07118 PRK07118
Fe-S cluster domain-containing protein;
55-175 8.89e-11

Fe-S cluster domain-containing protein;


Pssm-ID: 235941 [Multi-domain]  Cd Length: 280  Bit Score: 62.26  E-value: 8.89e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954  55 KLVFNGSK-----CDLDGACAKACPVGIKKVDDRFPY-SKGHCVLCEKCVDICPAEIISLpgkaeKPKKEIII----PQE 124
Cdd:PRK07118  128 ALLFGGPKgcsygCLGLGSCVAACPFDAIHIENGLPVvDEDKCTGCGACVKACPRNVIEL-----IPKSARVFvacnSKD 202

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2485681954 125 PIAVTKD-----CVACGVCVPECPVDAISIED-IAVIDTDKCIYCTVCSQTCPWNAI 175
Cdd:PRK07118  203 KGKAVKKvcevgCIGCGKCVKACPAGAITMENnLAVIDQEKCTSCGKCVEKCPTKAI 259
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 226-289 1.18e-08

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 51.21  E-value: 1.18e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2485681954 226 PEACPACGLCVESCPVEVISLEveyasakpvtDEGLVWSEEKCAYCGPCAIKCPTGAIKVVNPK 289
Cdd:COG2221    14 EEKCIGCGLCVAVCPTGAISLD----------DGKLVIDEEKCIGCGACIRVCPTGAIKGEKPK 67
Nar1 COG4624
Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];
132-287 1.19e-08

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];


Pssm-ID: 443663 [Multi-domain]  Cd Length: 450  Bit Score: 56.57  E-value: 1.19e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 132 CVACGVCVPECPVDAISIEDIAVIDTDKCIYCTVCSQTCPWNAIfvagklpqkrqktIKSFTVNEEECIGCEKCVEACPG 211
Cdd:COG4624    10 CCCIEEGDELLLLEEAERVLRIIILEALLPEHVDDDSACSCCPR-------------CCLCCCCCCRCCVAISCIQVRGI 76

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2485681954 212 SMIEYNGEALGVKlPEACPACGLCVESCPVEVISleveyasakpVTDEGLVWSEEKCAYCGPCAIKCPTGAIKVVN 287
Cdd:COG4624    77 IIIDKRGPSIIRD-KEKCKNCYPCVRACPVKAIK----------VDDGKAEIDEEKCISCGQCVAVCPFGAITEKS 141
PRK05113 PRK05113
electron transport complex protein RnfB; Provisional
 152-215 4.41e-08

electron transport complex protein RnfB; Provisional


Pssm-ID: 235347 [Multi-domain]  Cd Length: 191  Bit Score: 52.64  E-value: 4.41e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2485681954 152 IAVIDTDKCIYCTVCSQTCPWNAIFVAGKLPQkrqktiksfTVNEEECIGCEKCVEACPGSMIE 215
Cdd:PRK05113  108 VAFIDEDNCIGCTKCIQACPVDAIVGATKAMH---------TVISDLCTGCDLCVAPCPTDCIE 162
PRK07118 PRK07118
Fe-S cluster domain-containing protein;
228-363 4.39e-07

Fe-S cluster domain-containing protein;


Pssm-ID: 235941 [Multi-domain]  Cd Length: 280  Bit Score: 51.09  E-value: 4.39e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 228 ACPACGLCVESCPVEVISLEveyasakpvtdEGL-VWSEEKCAYCGPCAIKCPTGAIKVVnPKGLEL------PSRNKTE 300
Cdd:PRK07118  140 GCLGLGSCVAACPFDAIHIE-----------NGLpVVDEDKCTGCGACVKACPRNVIELI-PKSARVfvacnsKDKGKAV 207

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2485681954 301 KANEFAMCIRCGACAMKCPTGALKMgkmvhegkEYARVEFSPALCNECGECVDVCPQKTLELT 363
Cdd:PRK07118  208 KKVCEVGCIGCGKCVKACPAGAITM--------ENNLAVIDQEKCTSCGKCVEKCPTKAIRIL 262
ferrodoxin_EFR1 NF038196
EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...
 128-185 8.55e-07

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).


Pssm-ID: 468407 [Multi-domain]  Cd Length: 243  Bit Score: 49.86  E-value: 8.55e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2485681954 128 VTKDCVACGVCVPECPVDAISIEDIAVIDTDKCIYCTVCSQTCPWNAIFVaGKLPQKR 185
Cdd:NF038196  183 VTDKCIGCGICAKVCPVNNIEMEDGKPVWGHNCTHCLACIHRCPKEAIEY-GKKTKKK 239
rnfB TIGR01944
electron transport complex, RnfABCDGE type, B subunit; The six subunit complex RnfABCDGE in ...
 194-249 8.95e-07

electron transport complex, RnfABCDGE type, B subunit; The six subunit complex RnfABCDGE in Rhodobacter capsulatus encodes an apparent NADH oxidoreductase responsible for electron transport to nitrogenase, necessary for nitrogen fixation. A closely related complex in E. coli, RsxABCDGE (Reducer of SoxR), reduces the 2Fe-2S-containing superoxide sensor SoxR, active as a transcription factor when oxidized. This family of putative NADH oxidoreductase complexes exists in many of the same species as the related NQR, a Na(+)-translocating NADH-quinone reductase, but is distinct. This model describes the B subunit. [Energy metabolism, Electron transport]


Pssm-ID: 273887 [Multi-domain]  Cd Length: 165  Bit Score: 48.64  E-value: 8.95e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2485681954 194 VNEEECIGCEKCVEACPGSMIEYNGEALGVKLPEACPACGLCVESCPVEVISLEVE 249
Cdd:TIGR01944 110 IDEDNCIGCTKCIQACPVDAIVGAAKAMHTVIADECTGCDLCVEPCPTDCIEMIPV 165
napF TIGR00402
ferredoxin-type protein NapF; The gene codes for a ferredoxin-type cytosolic protein, NapF, of ...
 306-360 2.23e-06

ferredoxin-type protein NapF; The gene codes for a ferredoxin-type cytosolic protein, NapF, of the periplasmic nitrate reductase system, as in Escherichia coli. NapF interacts with the catalytic subunit, NapA, and may be an accessory protein for NapA maturation. [Energy metabolism, Electron transport]


Pssm-ID: 273060 [Multi-domain]  Cd Length: 101  Bit Score: 45.71  E-value: 2.23e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2485681954 306 AMCIRCGACAMKCPTGALKMGKmvhegKEYARVEFSPALCNECGECVDVCPQKTL 360
Cdd:TIGR00402  34 AVCTRCGECASACENNILQLGQ-----QGQPTVEFDNAECDFCGKCAEACPTNAF 83
NapH COG0348
Polyferredoxin NapH [Energy production and conversion];
4-49 4.49e-06

Polyferredoxin NapH [Energy production and conversion];


Pssm-ID: 440117 [Multi-domain]  Cd Length: 263  Bit Score: 47.75  E-value: 4.49e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 2485681954   4 ISIQEDACLVCNACAKACPTEaIEIA----PFKTCIQCFSCATACPTGAL 49
Cdd:COG0348   205 VRYDRGDCIDCGLCVKVCPMG-IDIRkgeiNQSECINCGRCIDACPKDAI 253
PRK09898 PRK09898
ferredoxin-like protein;
9-80 7.38e-06

ferredoxin-like protein;


Pssm-ID: 182135 [Multi-domain]  Cd Length: 208  Bit Score: 46.37  E-value: 7.38e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954   9 DACLVCN--ACAKACPTEAIEIAP--------FKTCIQCFSCATACPTG-ALVEKDGKlvfNGSKCDLDGACAKACPVGI 77
Cdd:PRK09898  121 DTCRQCKepQCMNVCPIGAITWQQkegcitvdHKRCIGCSACTTACPWMmATVNTESK---KSSKCVLCGECANACPTGA 197


                  ...
gi 2485681954  78 KKV 80
Cdd:PRK09898  198 LKI 200
Fer4_7 pfam12838
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 308-356 1.15e-05

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 463724 [Multi-domain]  Cd Length: 51  Bit Score: 42.51  E-value: 1.15e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 2485681954 308 CIRCGACAMKCPTGALKMGKmVHEGKEYARVEFSPALCNECGECVDVCP 356
Cdd:pfam12838   1 CIGCGACVAACPVGAITLDE-VGEKKGTKTVVIDPERCVGCGACVAVCP 48
FDH_beta_like cd16366
beta FeS subunits of formate dehydrogenase N (FDH-N) and similar proteins; This family ...
 9-76 2.45e-05

beta FeS subunits of formate dehydrogenase N (FDH-N) and similar proteins; This family contains beta FeS subunits of several dehydrogenases in the DMSO reductase superfamily, including formate dehydrogenase N (FDH-N), tungsten-containing formate dehydrogenase (W-FDH) and other similar proteins. FDH-N is a major component of nitrate respiration of Escherichia coli; it catalyzes the oxidation of formate to carbon dioxide, donating the electrons to a second substrate to a cytochrome. W-FDH contains a tungsten instead of molybdenum at the catalytic center and seems to be exclusively found in organisms such as hyperthermophilic archaea that live in extreme environments. It catalyzes the oxidation of formate to carbon dioxide, donating the electrons to a second substrate.


Pssm-ID: 319888 [Multi-domain]  Cd Length: 156  Bit Score: 43.93  E-value: 2.45e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954   9 DACLVCN--ACAKACPTEAIEIAPF-------KTCIQCFSCATACPTGA--LVEKDGKLvfngSKCD---------LDGA 68
Cdd:cd16366    68 DQCMHCTdaGCLAACPTGAIIRTETgtvvvdpETCIGCGYCVNACPFDIprFDEETGRV----AKCTlcydrisngLQPA 143


                  ....*...
gi 2485681954  69 CAKACPVG 76
Cdd:cd16366   144 CVKTCPTG 151
Fer4_21 pfam14697
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 153-210 3.46e-05

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 434137 [Multi-domain]  Cd Length: 59  Bit Score: 41.11  E-value: 3.46e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2485681954 153 AVIDTDKCIYCTVCSQTCPWN---AIFVAGKlpqkrqktiKSFTVNEEECIGCEKCVEACP 210
Cdd:pfam14697   1 ARIDEDTCIGCGKCYIACPDTshqAIVGDGK---------RHHTVIEDECTGCNLCVSVCP 52
flavo_MJ0208 TIGR02700
archaeoflavoprotein, MJ0208 family; This model describes one of two paralogous families of ...
 32-74 1.93e-04

archaeoflavoprotein, MJ0208 family; This model describes one of two paralogous families of archaealflavoprotein. The other, described by TIGR02699 and typified by the partially characterized AF1518 of Archaeoglobus fulgidus, is a homodimeric FMN-containing flavoprotein that accepts electrons from ferredoxin and can transfer them to various oxidoreductases. The function of this protein family is unknown. [Unknown function, General]


Pssm-ID: 131747 [Multi-domain]  Cd Length: 234  Bit Score: 42.55  E-value: 1.93e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 2485681954  32 KTCIQCFSCATACPTGALVEKDGKLVFNGSKCDLDGACAKACP 74
Cdd:TIGR02700 148 KRCKGCGICVDACPRSAIDMVDGKAFIRLLKCVGCGKCKEACP 190
Fer4_7 pfam12838
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 132-174 4.84e-04

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 463724 [Multi-domain]  Cd Length: 51  Bit Score: 37.89  E-value: 4.84e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2485681954 132 CVACGVCVPECPVDAISIE--------DIAVIDTDKCIYCTVCSQTCPWNA 174
Cdd:pfam12838   1 CIGCGACVAACPVGAITLDevgekkgtKTVVIDPERCVGCGACVAVCPTGA 51
ferrodoxin_EFR1 NF038196
EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...
 9-48 9.77e-04

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).


Pssm-ID: 468407 [Multi-domain]  Cd Length: 243  Bit Score: 40.23  E-value: 9.77e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 2485681954   9 DACLVCNACAKACPTEAIEIAPFK-----TCIQCFSCATACPTGA 48
Cdd:NF038196  185 DKCIGCGICAKVCPVNNIEMEDGKpvwghNCTHCLACIHRCPKEA 229
ferrodoxin_EFR1 NF038196
EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...
 227-283 1.76e-03

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).


Pssm-ID: 468407 [Multi-domain]  Cd Length: 243  Bit Score: 39.46  E-value: 1.76e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2485681954 227 EACPACGLCVESCPVEVISLEVEyasaKPvtdeglVWSeEKCAYCGPCAIKCPTGAI 283
Cdd:NF038196  185 DKCIGCGICAKVCPVNNIEMEDG----KP------VWG-HNCTHCLACIHRCPKEAI 230
ferrodoxin_EFR1 NF038196
EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...
 255-328 6.65e-03

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).


Pssm-ID: 468407 [Multi-domain]  Cd Length: 243  Bit Score: 37.92  E-value: 6.65e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2485681954 255 PVTDEGLvWSEEKCAYCGPCAIKCPTGAIKVVNPKglelPSRNKTekanefamCIRCGACAMKCPTGALKMGKM 328
Cdd:NF038196  175 KVKDKKF-HVTDKCIGCGICAKVCPVNNIEMEDGK----PVWGHN--------CTHCLACIHRCPKEAIEYGKK 235
ferrodoxin_EFR1 NF038196
EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...
 345-389 6.95e-03

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).


Pssm-ID: 468407 [Multi-domain]  Cd Length: 243  Bit Score: 37.92  E-value: 6.95e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2485681954 345 CNECGECVDVCPQKTLELTgdDKMPL-KGYCVMCLKCIEAC--------NKTKK 389
Cdd:NF038196  187 CIGCGICAKVCPVNNIEME--DGKPVwGHNCTHCLACIHRCpkeaieygKKTKK 238
 
Name Accession Description Interval E-value
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 56-177 7.36e-22

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 90.15  E-value: 7.36e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954  56 LVFNGSKCDLDGACAKACPVGIKKVDDRFPYSKG------HCVLCEKCVDICPAEIISLPGKAE---KPKKEIIIPQEpi 126
Cdd:cd10549     1 LKYDPEKCIGCGICVKACPTDAIELGPNGAIARGpeidedKCVFCGACVEVCPTGAIELTPEGKeyvPKEKEAEIDEE-- 78

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2485681954 127 avtkDCVACGVCVPECPVDAISIEDI--AVIDTDKCIYCTVCSQTCPWNAIFV 177
Cdd:cd10549    79 ----KCIGCGLCVKVCPVDAITLEDEleIVIDKEKCIGCGICAEVCPVNAIKL 127
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 125-247 7.66e-22

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 90.15  E-value: 7.66e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 125 PIAVTKDCVACGVCVPECPVDAISIEDI------AVIDTDKCIYCTVCSQTCPWNAIFVaGKLPQKRQKTIKSFTVNEEE 198
Cdd:cd10549     1 LKYDPEKCIGCGICVKACPTDAIELGPNgaiargPEIDEDKCVFCGACVEVCPTGAIEL-TPEGKEYVPKEKEAEIDEEK 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 2485681954 199 CIGCEKCVEACPGSMIEYNGEALGVKLPEACPACGLCVESCPVEVISLE 247
Cdd:cd10549    80 CIGCGLCVKVCPVDAITLEDELEIVIDKEKCIGCGICAEVCPVNAIKLV 128
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 226-363 5.78e-17

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 76.67  E-value: 5.78e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 226 PEACPACGLCVESCPVEVISLEVEYASAKPVtdeglVWSEEKCAYCGPCAIKCPTGAIKVVNPKGLELPSRNKTEKANEf 305
Cdd:cd10549     5 PEKCIGCGICVKACPTDAIELGPNGAIARGP-----EIDEDKCVFCGACVEVCPTGAIELTPEGKEYVPKEKEAEIDEE- 78

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2485681954 306 aMCIRCGACAMKCPTGALKMgkmvhegKEYARVEFSPALCNECGECVDVCPQKTLELT 363
Cdd:cd10549    79 -KCIGCGLCVKVCPVDAITL-------EDELEIVIDKEKCIGCGICAEVCPVNAIKLV 128
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 261-384 7.86e-16

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 73.59  E-value: 7.86e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 261 LVWSEEKCAYCGPCAIKCPTGAIKVVNPKGLELPSrnktekANEFAMCIRCGACAMKCPTGALKMGKMVHE-GKEYARVE 339
Cdd:cd10549     1 LKYDPEKCIGCGICVKACPTDAIELGPNGAIARGP------EIDEDKCVFCGACVEVCPTGAIELTPEGKEyVPKEKEAE 74

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 2485681954 340 FSPALCNECGECVDVCPQKTLELTGDDKM-PLKGYCVMCLKCIEAC 384
Cdd:cd10549    75 IDEEKCIGCGLCVKVCPVDAITLEDELEIvIDKEKCIGCGICAEVC 120
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
125-175 3.57e-11

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 58.59  E-value: 3.57e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2485681954 125 PIAVTKDCVACGVCVPECPVDAISIED-IAVIDTDKCIYCTVCSQTCPWNAI 175
Cdd:COG2768     6 PYVDEEKCIGCGACVKVCPVGAISIEDgKAVIDPEKCIGCGACIEVCPVGAI 57
PRK07118 PRK07118
Fe-S cluster domain-containing protein;
55-175 8.89e-11

Fe-S cluster domain-containing protein;


Pssm-ID: 235941 [Multi-domain]  Cd Length: 280  Bit Score: 62.26  E-value: 8.89e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954  55 KLVFNGSK-----CDLDGACAKACPVGIKKVDDRFPY-SKGHCVLCEKCVDICPAEIISLpgkaeKPKKEIII----PQE 124
Cdd:PRK07118  128 ALLFGGPKgcsygCLGLGSCVAACPFDAIHIENGLPVvDEDKCTGCGACVKACPRNVIEL-----IPKSARVFvacnSKD 202

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2485681954 125 PIAVTKD-----CVACGVCVPECPVDAISIED-IAVIDTDKCIYCTVCSQTCPWNAI 175
Cdd:PRK07118  203 KGKAVKKvcevgCIGCGKCVKACPAGAITMENnLAVIDQEKCTSCGKCVEKCPTKAI 259
NapF_like cd10564
NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, ...
 34-152 3.59e-10

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, the iron-sulfur subunit of periplasmic nitrate reductase. The periplasmic nitrate reductase NapABC of Escherichia coli likely functions during anaerobic growth in low-nitrate environments; napF operon expression is activated by cyclic AMP receptor protein (Crp). NapF is a subfamily of the beta subunit of DMSO reductase (DMSOR) family. DMSOR family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319886 [Multi-domain]  Cd Length: 139  Bit Score: 57.64  E-value: 3.59e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954  34 CIQCFSCATACPTGALVEKDG---KLVFNGSKCDLDGACAKACPVGIKKVDDRFPYS-----KGHC-----VLCEKCVDI 100
Cdd:cd10564    15 CTRCGDCVEACPEGIIVRGDGgfpELDFSRGECTFCGACAEACPEGALDPAREAPWPlraeiGDSClalqgVECRSCQDA 94

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2485681954 101 CPAEIISLPGKaekpkkeIIIPQEPIAVTKDCVACGVCVPECPVDAISIEDI 152
Cdd:cd10564    95 CPTQAIRFRPR-------LGGIALPELDADACTGCGACVSVCPVGAITLTPL 139
IorA COG4231
TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...
 129-182 5.18e-10

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];


Pssm-ID: 443375 [Multi-domain]  Cd Length: 76  Bit Score: 55.43  E-value: 5.18e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2485681954 129 TKDCVACGVCVPECPVDAISIED-IAVIDTDKCIYCTVCSQTCPWNAIFVAGKLP 182
Cdd:COG4231    21 EDKCTGCGACVKVCPADAIEEGDgKAVIDPDLCIGCGSCVQVCPVDAIKLEKRVP 75
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 120-175 1.05e-08

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 51.59  E-value: 1.05e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2485681954 120 IIPQEPIAVTKD-CVACGVCVPECPVDAISIED-IAVIDTDKCIYCTVCSQTCPWNAI 175
Cdd:COG2221     4 IIGTWPPKIDEEkCIGCGLCVAVCPTGAISLDDgKLVIDEEKCIGCGACIRVCPTGAI 61
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 226-289 1.18e-08

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 51.21  E-value: 1.18e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2485681954 226 PEACPACGLCVESCPVEVISLEveyasakpvtDEGLVWSEEKCAYCGPCAIKCPTGAIKVVNPK 289
Cdd:COG2221    14 EEKCIGCGLCVAVCPTGAISLD----------DGKLVIDEEKCIGCGACIRVCPTGAIKGEKPK 67
Nar1 COG4624
Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];
132-287 1.19e-08

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];


Pssm-ID: 443663 [Multi-domain]  Cd Length: 450  Bit Score: 56.57  E-value: 1.19e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 132 CVACGVCVPECPVDAISIEDIAVIDTDKCIYCTVCSQTCPWNAIfvagklpqkrqktIKSFTVNEEECIGCEKCVEACPG 211
Cdd:COG4624    10 CCCIEEGDELLLLEEAERVLRIIILEALLPEHVDDDSACSCCPR-------------CCLCCCCCCRCCVAISCIQVRGI 76

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2485681954 212 SMIEYNGEALGVKlPEACPACGLCVESCPVEVISleveyasakpVTDEGLVWSEEKCAYCGPCAIKCPTGAIKVVN 287
Cdd:COG4624    77 IIIDKRGPSIIRD-KEKCKNCYPCVRACPVKAIK----------VDDGKAEIDEEKCISCGQCVAVCPFGAITEKS 141
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
193-247 1.76e-08

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 56.41  E-value: 1.76e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2485681954 193 TVNEEECIGCEKCVEACPGSMIEYNGEALGVKLPEACPACGLCVESCPVEVISLE 247
Cdd:COG1148   492 EVDPEKCTGCGRCVEVCPYGAISIDEKGVAEVNPALCKGCGTCAAACPSGAISLK 546
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 129-177 1.92e-08

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 50.51  E-value: 1.92e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2485681954 129 TKDCVACGVCVPECPVDAISIED-----IAVIDTDKCIYCTVCSQTCPWNAIFV 177
Cdd:COG1143     1 EDKCIGCGLCVRVCPVDAITIEDgepgkVYVIDPDKCIGCGLCVEVCPTGAISM 54
DMSOR_beta_like cd16373
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 228-356 2.59e-08

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319895 [Multi-domain]  Cd Length: 154  Bit Score: 52.64  E-value: 2.59e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 228 ACPACGLCVESCPVEVISLEVEYASAKPVTDEGLVWSEEKCAYCG-PCAIKCPTGAIKVVNPKglELPSRNKTEKANE-- 304
Cdd:cd16373    15 LCIRCGLCVEACPTGVIQPAGLEDGLEGGRTPYLDPREGPCDLCCdACVEVCPTGALRPLDLE--EQKVKMGVAVIDKdr 92

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2485681954 305 ---FAMCIRCGACAMKCPTGALKMgkmvHEGKEYARVEFSPALCNECGECVDVCP 356
Cdd:cd16373    93 claWQGGTDCGVCVEACPTEAIAI----VLEDDVLRPVVDEDKCVGCGLCEYVCP 143
PRK05113 PRK05113
electron transport complex protein RnfB; Provisional
 152-215 4.41e-08

electron transport complex protein RnfB; Provisional


Pssm-ID: 235347 [Multi-domain]  Cd Length: 191  Bit Score: 52.64  E-value: 4.41e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2485681954 152 IAVIDTDKCIYCTVCSQTCPWNAIFVAGKLPQkrqktiksfTVNEEECIGCEKCVEACPGSMIE 215
Cdd:PRK05113  108 VAFIDEDNCIGCTKCIQACPVDAIVGATKAMH---------TVISDLCTGCDLCVAPCPTDCIE 162
PreA COG1146
NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...
 128-182 8.18e-08

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];


Pssm-ID: 440761 [Multi-domain]  Cd Length: 67  Bit Score: 48.94  E-value: 8.18e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2485681954 128 VTKDCVACGVCVPECPVDAISIEDIA----VIDTDKCIYCTVCSQTCPWNAIFVAGKLP 182
Cdd:COG1146     6 DTDKCIGCGACVEVCPVDVLELDEEGkkalVINPEECIGCGACELVCPVGAITVEDDEP 64
PRK06991 PRK06991
electron transport complex subunit RsxB;
152-222 1.46e-07

electron transport complex subunit RsxB;


Pssm-ID: 235903 [Multi-domain]  Cd Length: 270  Bit Score: 52.49  E-value: 1.46e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2485681954 152 IAVIDTDKCIYCTVCSQTCPWNAIFVAGKlpqkrqktiKSFTVNEEECIGCEKCVEACPG---SMIEYNGEALG 222
Cdd:PRK06991   79 VAVIDEQLCIGCTLCMQACPVDAIVGAPK---------QMHTVLADLCTGCDLCVPPCPVdciDMVPVTGERTG 143
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 187-247 1.76e-07

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 47.80  E-value: 1.76e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2485681954 187 KTIKSFTVNEEECIGCEKCVEACPGSMIEYNGEALGVKLPEACPACGLCVESCPVEVISLE 247
Cdd:COG1149     1 VKRKIPVIDEEKCIGCGLCVEVCPEGAIKLDDGGAPVVDPDLCTGCGACVGVCPTGAITLE 61
PRK07118 PRK07118
Fe-S cluster domain-containing protein;
160-289 1.82e-07

Fe-S cluster domain-containing protein;


Pssm-ID: 235941 [Multi-domain]  Cd Length: 280  Bit Score: 52.24  E-value: 1.82e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 160 CIYCTVCSQTCPWNAIFVAGKLPQkrqktiksftVNEEECIGCEKCVEACPGSMIEYNGEALGVKLP------------- 226
Cdd:PRK07118  141 CLGLGSCVAACPFDAIHIENGLPV----------VDEDKCTGCGACVKACPRNVIELIPKSARVFVAcnskdkgkavkkv 210

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2485681954 227 --EACPACGLCVESCPVEVISLEveyaSAKPVTDeglvwsEEKCAYCGPCAIKCPTGAIKVVNPK 289
Cdd:PRK07118  211 ceVGCIGCGKCVKACPAGAITME----NNLAVID------QEKCTSCGKCVEKCPTKAIRILNKP 265
DMSOR_beta_like cd16373
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 32-171 1.83e-07

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319895 [Multi-domain]  Cd Length: 154  Bit Score: 50.33  E-value: 1.83e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954  32 KTCIQCFSCATACPTGALVEKDGKlvfngskcdlDGACAKACPVgikkvddrFPYSKGHCVLCEK-CVDICPAEIISLPG 110
Cdd:cd16373    14 ALCIRCGLCVEACPTGVIQPAGLE----------DGLEGGRTPY--------LDPREGPCDLCCDaCVEVCPTGALRPLD 75

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2485681954 111 KAEKPKK---EIIIPQEPIAVTKDcVACGVCVPECPVDAISIED-----IAVIDTDKCIYCTVCSQTCP 171
Cdd:cd16373    76 LEEQKVKmgvAVIDKDRCLAWQGG-TDCGVCVEACPTEAIAIVLeddvlRPVVDEDKCVGCGLCEYVCP 143
PRK13795 PRK13795
hypothetical protein; Provisional
 132-171 2.01e-07

hypothetical protein; Provisional


Pssm-ID: 237510 [Multi-domain]  Cd Length: 636  Bit Score: 53.07  E-value: 2.01e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 2485681954 132 CVACGVCVPECPVDAISIED---IAVIDTDKCIYCTVCSQTCP 171
Cdd:PRK13795  583 CVGCGVCVGACPTGAIRIEEgkrKISVDEEKCIHCGKCTEVCP 625
RnfB COG2878
Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and ...
 126-284 2.14e-07

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase


Pssm-ID: 442125 [Multi-domain]  Cd Length: 254  Bit Score: 51.53  E-value: 2.14e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 126 IAVTKDCVACGVCVPECPVDAISIEDIAVIDTDK-----CIYCTVCSQTCPWNAIFVAGK-LPqkrqktiksfTVNEEEC 199
Cdd:COG2878   100 VAVVRCNGGCEKAKPKYEYDGIKDCRAAVIGGPKgceygCIGCGDCIKACPFDAIVGAAKgMH----------TVDEDKC 169

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 200 IGCEKCVEACPG---SMIEYNGEALGV-----KLPEACPAC-GLCVESCPVEVISLEVEYASAKPvtdeglvwsEEKCAY 270
Cdd:COG2878   170 TGCGLCVEACPVdciEMVPVSPTVVVSswdkgKAVRKVVGCiGLCCKKCCPAAAITVNNLAAIID---------YKKCTC 240

                         170
                  ....*....|....
gi 2485681954 271 CGPCAIKCPTGAIK 284
Cdd:COG2878   241 CGCCEKCCPTAIIA 254
NapF COG1145
Ferredoxin [Energy production and conversion];
88-325 2.37e-07

Ferredoxin [Energy production and conversion];


Pssm-ID: 440760 [Multi-domain]  Cd Length: 238  Bit Score: 51.26  E-value: 2.37e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954  88 KGHCVLCEKCVDICPAEIISLPGKAEKPKKEIIIPQEPIAVTKDCVACGVCVPECPVDAISIEDIAVIDTDKCIYCTVCS 167
Cdd:COG1145     4 LLDLKEALSPKLKVLYAVVTGILGKIILNVIAGALLKAVALGGLLPIIGILAKEAFDALKDVLGILGAIVIGIGAGEIVR 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 168 QTCPWNAIFVAGKLPQKRQKTIKSFTVNEEECIGCEKCVEACPGSMIEYNGEALGVKLPEACPACGLCVESCPVEVISLE 247
Cdd:COG1145    84 VGIAAADLNLKAVALVLLLALAVAGAAKRLIISAVKLVAGLVVAAGEVLLVIAAALAEAGLAILGAAAPVDALAISGGKK 163

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2485681954 248 VEYASAKPVTDEGLVWSEEKCAYCGPCAIKCPTGAIKVVNPKGLELPSRNKtekanefamCIRCGACAMKCPTGALKM 325
Cdd:COG1145   164 IEEELKIAIKKAKAVIDAEKCIGCGLCVKVCPTGAIRLKDGKPQIVVDPDK---------CIGCGACVKVCPVGAISL 232
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 152-216 2.39e-07

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 47.42  E-value: 2.39e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2485681954 152 IAVIDTDKCIYCTVCSQTCPWNAIFVAGKlpqkrqktiKSFTVNEEECIGCEKCVEACPGSMIEY 216
Cdd:COG1149     5 IPVIDEEKCIGCGLCVEVCPEGAIKLDDG---------GAPVVDPDLCTGCGACVGVCPTGAITL 60
PRK05113 PRK05113
electron transport complex protein RnfB; Provisional
 194-246 2.41e-07

electron transport complex protein RnfB; Provisional


Pssm-ID: 235347 [Multi-domain]  Cd Length: 191  Bit Score: 50.71  E-value: 2.41e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2485681954 194 VNEEECIGCEKCVEACPGSMIEYNGEALGVKLPEACPACGLCVESCPVEVISL 246
Cdd:PRK05113  111 IDEDNCIGCTKCIQACPVDAIVGATKAMHTVISDLCTGCDLCVAPCPTDCIEM 163
DMSOR_beta_like cd16373
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 10-150 2.84e-07

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319895 [Multi-domain]  Cd Length: 154  Bit Score: 49.56  E-value: 2.84e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954  10 ACLVCNACAKACPTEAIEIAPFKT----------------CIQCFS-CATACPTGALvekdgklvfngSKCDLDGACAKa 72
Cdd:cd16373    15 LCIRCGLCVEACPTGVIQPAGLEDgleggrtpyldpregpCDLCCDaCVEVCPTGAL-----------RPLDLEEQKVK- 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954  73 cpVGIKKVDDRFPYSKGHCVLCEKCVDICPaeiisLPGKAEKPKKEIIIPQEpiaVTKDCVACGVCVPECPVD---AISI 149
Cdd:cd16373    83 --MGVAVIDKDRCLAWQGGTDCGVCVEACP-----TEAIAIVLEDDVLRPVV---DEDKCVGCGLCEYVCPVEppkAIVV 152


                  .
gi 2485681954 150 E 150
Cdd:cd16373   153 E 153
PRK07118 PRK07118
Fe-S cluster domain-containing protein;
228-363 4.39e-07

Fe-S cluster domain-containing protein;


Pssm-ID: 235941 [Multi-domain]  Cd Length: 280  Bit Score: 51.09  E-value: 4.39e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 228 ACPACGLCVESCPVEVISLEveyasakpvtdEGL-VWSEEKCAYCGPCAIKCPTGAIKVVnPKGLEL------PSRNKTE 300
Cdd:PRK07118  140 GCLGLGSCVAACPFDAIHIE-----------NGLpVVDEDKCTGCGACVKACPRNVIELI-PKSARVfvacnsKDKGKAV 207

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2485681954 301 KANEFAMCIRCGACAMKCPTGALKMgkmvhegkEYARVEFSPALCNECGECVDVCPQKTLELT 363
Cdd:PRK07118  208 KKVCEVGCIGCGKCVKACPAGAITM--------ENNLAVIDQEKCTSCGKCVEKCPTKAIRIL 262
IorA COG4231
TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...
 187-249 4.43e-07

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];


Pssm-ID: 443375 [Multi-domain]  Cd Length: 76  Bit Score: 46.96  E-value: 4.43e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2485681954 187 KTIKSFTVNEEECIGCEKCVEACPGSMIEYNGEALGVKlPEACPACGLCVESCPVEVISLEVE 249
Cdd:COG4231    12 TTAMRYVIDEDKCTGCGACVKVCPADAIEEGDGKAVID-PDLCIGCGSCVQVCPVDAIKLEKR 73
HycB COG1142
Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];
4-108 5.50e-07

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];


Pssm-ID: 440757 [Multi-domain]  Cd Length: 138  Bit Score: 48.50  E-value: 5.50e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954   4 ISIQEDACLVCNACAKACPT--EAIEIAPFK---------------TCIQCF--SCATACPTGALVEKDGKLVFNGSKCD 64
Cdd:COG1142     5 IIADPEKCIGCRTCEAACAVahEGEEGEPFLprirvvrkagvsapvQCRHCEdaPCAEVCPVGAITRDDGAVVVDEEKCI 84

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2485681954  65 LDGACAKACPVGIKKVDDRFPYSKGH-CVLCE------KCVDICPAEIISL 108
Cdd:COG1142    85 GCGLCVLACPFGAITMVGEKSRAVAVkCDLCGgreggpACVEACPTGALRL 135
DMSOR_beta_like cd16372
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 223-362 5.52e-07

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319894 [Multi-domain]  Cd Length: 125  Bit Score: 48.10  E-value: 5.52e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 223 VKLPEACPACGLCVESCPVEVISLEVEYASAKPVTDEGLVWSEEKCAYCGPCAIKCPTGAIKVvNPKGLELPSRNKteka 302
Cdd:cd16372     4 VTDPEKCIGCLQCEEACSKTFFKEEDREKSCIRITETEGGYAINVCNQCGECIDVCPTGAITR-DANGVVMINKKL---- 78

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 303 nefamCIRCGACAMKCPTGALKMgkmvHEGKEyarvefSPALCNECGECVDVCPQKTLEL 362
Cdd:cd16372    79 -----CVGCLMCVGFCPEGAMFK----HEDYP------EPFKCIACGICVKACPTGALEL 123
Nar1 COG4624
Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];
226-324 5.53e-07

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];


Pssm-ID: 443663 [Multi-domain]  Cd Length: 450  Bit Score: 51.18  E-value: 5.53e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 226 PEACPACGLCVESCPVEVISLEVEYASAKPVTDEGLVWSEEKCAYCGPCAIKCPTGAIKVVNpkglelpsrNKTEKANEf 305
Cdd:COG4624    51 CPRCCLCCCCCCRCCVAISCIQVRGIIIIDKRGPSIIRDKEKCKNCYPCVRACPVKAIKVDD---------GKAEIDEE- 120

                          90
                  ....*....|....*....
gi 2485681954 306 aMCIRCGACAMKCPTGALK 324
Cdd:COG4624   121 -KCISCGQCVAVCPFGAIT 138
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 308-363 6.09e-07

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 46.28  E-value: 6.09e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2485681954 308 CIRCGACAMKCPTGALKMGkmvhEGKEYARVEFSPALCNECGECVDVCPQKTLELT 363
Cdd:COG1143     4 CIGCGLCVRVCPVDAITIE----DGEPGKVYVIDPDKCIGCGLCVEVCPTGAISMT 55
PRK06991 PRK06991
electron transport complex subunit RsxB;
194-265 6.52e-07

electron transport complex subunit RsxB;


Pssm-ID: 235903 [Multi-domain]  Cd Length: 270  Bit Score: 50.18  E-value: 6.52e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2485681954 194 VNEEECIGCEKCVEACPGSMIEYNGEALGVKLPEACPACGLCVESCPVEVISLeveyasaKPVTDEGLVWSE 265
Cdd:PRK06991   82 IDEQLCIGCTLCMQACPVDAIVGAPKQMHTVLADLCTGCDLCVPPCPVDCIDM-------VPVTGERTGWDA 146
ndhI CHL00014
NADH dehydrogenase subunit I
 158-226 6.55e-07

NADH dehydrogenase subunit I


Pssm-ID: 214334 [Multi-domain]  Cd Length: 167  Bit Score: 48.99  E-value: 6.55e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 158 DKCIYCTVCSQTCPWNAIFVAGKLPQ-KRQKTIKSFTVNEEECIGCEKCVEACPG---SMIE-------------YNGEA 220
Cdd:CHL00014   59 DKCIACEVCVRVCPIDLPVVDWKLETdIRKKRLLNYSIDFGVCIFCGNCVEYCPTnclSMTEeyelstydrhelnYNQIA 138


                  ....*.
gi 2485681954 221 LGvKLP 226
Cdd:CHL00014  139 LG-RLP 143
NapH COG0348
Polyferredoxin NapH [Energy production and conversion];
40-116 6.57e-07

Polyferredoxin NapH [Energy production and conversion];


Pssm-ID: 440117 [Multi-domain]  Cd Length: 263  Bit Score: 50.45  E-value: 6.57e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954  40 CATACPTGA---LVEKDG--KLVFNGSKCDLDGACAKACPVGIKKVDDRFPYSkgHCVLCEKCVDICPAEIISLPGKAEK 114
Cdd:COG0348   184 CRYLCPYGAfqgLLSDLStlRVRYDRGDCIDCGLCVKVCPMGIDIRKGEINQS--ECINCGRCIDACPKDAIRFSSRGEK 261


                  ..
gi 2485681954 115 PK 116
Cdd:COG0348   262 TR 263
NapH COG0348
Polyferredoxin NapH [Energy production and conversion];
164-249 7.26e-07

Polyferredoxin NapH [Energy production and conversion];


Pssm-ID: 440117 [Multi-domain]  Cd Length: 263  Bit Score: 50.06  E-value: 7.26e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 164 TVCSQTCPWNAIFVAGKlpqkRQKTIKsFTVNEEECIGCEKCVEACPGSMIEYNGEalgvKLPEACPACGLCVESCPVEV 243
Cdd:COG0348   182 QWCRYLCPYGAFQGLLS----DLSTLR-VRYDRGDCIDCGLCVKVCPMGIDIRKGE----INQSECINCGRCIDACPKDA 252


                  ....*.
gi 2485681954 244 ISLEVE 249
Cdd:COG0348   253 IRFSSR 258
DMSOR_beta-like cd04410
Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta ...
 192-326 7.64e-07

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319870 [Multi-domain]  Cd Length: 136  Bit Score: 48.15  E-value: 7.64e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 192 FTVNEEECIGCEKCVEAC------------PGSMIEYNGEALGVKLPEACPACG--LCVESCPVEVISleveyasakpVT 257
Cdd:cd04410     1 LVVDLDRCIGCGTCEVACkqehglrpgpdwSRIKVIEGGGLERAFLPVSCMHCEdpPCVKACPTGAIY----------KD 70

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2485681954 258 DEGLV-WSEEKCAYCGPCAIKCPTGAIKVVnpkglelPSRNKTEKanefamCIRCG---------ACAMKCPTGALKMG 326
Cdd:cd04410    71 EDGIVlIDEDKCIGCGSCVEACPYGAIVFD-------PEPGKAVK------CDLCGdrldeglepACVKACPTGALTFG 136
ferrodoxin_EFR1 NF038196
EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...
 128-185 8.55e-07

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).


Pssm-ID: 468407 [Multi-domain]  Cd Length: 243  Bit Score: 49.86  E-value: 8.55e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2485681954 128 VTKDCVACGVCVPECPVDAISIEDIAVIDTDKCIYCTVCSQTCPWNAIFVaGKLPQKR 185
Cdd:NF038196  183 VTDKCIGCGICAKVCPVNNIEMEDGKPVWGHNCTHCLACIHRCPKEAIEY-GKKTKKK 239
rnfB TIGR01944
electron transport complex, RnfABCDGE type, B subunit; The six subunit complex RnfABCDGE in ...
 194-249 8.95e-07

electron transport complex, RnfABCDGE type, B subunit; The six subunit complex RnfABCDGE in Rhodobacter capsulatus encodes an apparent NADH oxidoreductase responsible for electron transport to nitrogenase, necessary for nitrogen fixation. A closely related complex in E. coli, RsxABCDGE (Reducer of SoxR), reduces the 2Fe-2S-containing superoxide sensor SoxR, active as a transcription factor when oxidized. This family of putative NADH oxidoreductase complexes exists in many of the same species as the related NQR, a Na(+)-translocating NADH-quinone reductase, but is distinct. This model describes the B subunit. [Energy metabolism, Electron transport]


Pssm-ID: 273887 [Multi-domain]  Cd Length: 165  Bit Score: 48.64  E-value: 8.95e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2485681954 194 VNEEECIGCEKCVEACPGSMIEYNGEALGVKLPEACPACGLCVESCPVEVISLEVE 249
Cdd:TIGR01944 110 IDEDNCIGCTKCIQACPVDAIVGAAKAMHTVIADECTGCDLCVEPCPTDCIEMIPV 165
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
132-179 9.28e-07

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 50.63  E-value: 9.28e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 2485681954 132 CVACGVCVPECPVDAISIED--IAVIDTDKCIYCTVCSQTCPWNAIFVAG 179
Cdd:COG1148   498 CTGCGRCVEVCPYGAISIDEkgVAEVNPALCKGCGTCAAACPSGAISLKG 547
PRK09898 PRK09898
ferredoxin-like protein;
226-325 1.00e-06

ferredoxin-like protein;


Pssm-ID: 182135 [Multi-domain]  Cd Length: 208  Bit Score: 49.06  E-value: 1.00e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 226 PEACPACG--LCVESCPVEVISLEVEYASakpvtdegLVWSEEKCAYCGPCAIKCPTGaIKVVNPKglelpsrnkTEKAN 303
Cdd:PRK09898  120 ADTCRQCKepQCMNVCPIGAITWQQKEGC--------ITVDHKRCIGCSACTTACPWM-MATVNTE---------SKKSS 181

                          90       100
                  ....*....|....*....|..
gi 2485681954 304 EfamCIRCGACAMKCPTGALKM 325
Cdd:PRK09898  182 K---CVLCGECANACPTGALKI 200
DMSOR_beta_like cd16370
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 34-108 1.01e-06

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319892 [Multi-domain]  Cd Length: 131  Bit Score: 47.65  E-value: 1.01e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2485681954  34 CIQCF--SCATACPTGALVE-KDGKLVFNGSKCDLDGACAKACPVGIKKVDDRFPYSKgHCVLCEKCVDICPAEIISL 108
Cdd:cd16370    53 CRACEdpPCAEACPTGALEPrKGGGVVLDKEKCIGCGNCVKACIVGAIFWDEETNKPI-ICIHCGYCARYCPHDVLAM 129
PreA COG1146
NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...
 192-250 1.13e-06

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];


Pssm-ID: 440761 [Multi-domain]  Cd Length: 67  Bit Score: 45.47  E-value: 1.13e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2485681954 192 FTVNEEECIGCEKCVEACPGS--MIEYNGEALGVKLPEACPACGLCVESCPVEVISLEVEY 250
Cdd:COG1146     3 PVIDTDKCIGCGACVEVCPVDvlELDEEGKKALVINPEECIGCGACELVCPVGAITVEDDE 63
PRK13795 PRK13795
hypothetical protein; Provisional
 159-210 1.14e-06

hypothetical protein; Provisional


Pssm-ID: 237510 [Multi-domain]  Cd Length: 636  Bit Score: 50.76  E-value: 1.14e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2485681954 159 KCIYCTVCSQTCPWNAIFVAGKLpqkrqktiKSFTVNEEECIGCEKCVEACP 210
Cdd:PRK13795  582 ECVGCGVCVGACPTGAIRIEEGK--------RKISVDEEKCIHCGKCTEVCP 625
rnfB TIGR01944
electron transport complex, RnfABCDGE type, B subunit; The six subunit complex RnfABCDGE in ...
 145-215 1.16e-06

electron transport complex, RnfABCDGE type, B subunit; The six subunit complex RnfABCDGE in Rhodobacter capsulatus encodes an apparent NADH oxidoreductase responsible for electron transport to nitrogenase, necessary for nitrogen fixation. A closely related complex in E. coli, RsxABCDGE (Reducer of SoxR), reduces the 2Fe-2S-containing superoxide sensor SoxR, active as a transcription factor when oxidized. This family of putative NADH oxidoreductase complexes exists in many of the same species as the related NQR, a Na(+)-translocating NADH-quinone reductase, but is distinct. This model describes the B subunit. [Energy metabolism, Electron transport]


Pssm-ID: 273887 [Multi-domain]  Cd Length: 165  Bit Score: 48.26  E-value: 1.16e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2485681954 145 DAISIEDIAVIDTDKCIYCTVCSQTCPWNAIFVAGKLpqkrqktikSFTVNEEECIGCEKCVEACPGSMIE 215
Cdd:TIGR01944 100 GTIQPPMVALIDEDNCIGCTKCIQACPVDAIVGAAKA---------MHTVIADECTGCDLCVEPCPTDCIE 161
DMSOR_beta_like cd16372
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 32-151 1.29e-06

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319894 [Multi-domain]  Cd Length: 125  Bit Score: 46.95  E-value: 1.29e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954  32 KTCIQCFSCATACPTGALVEKDGKL----------VFNGSKCDLDGACAKACPVGIKKVDDRFPY--SKGHCVLCEKCVD 99
Cdd:cd16372     8 EKCIGCLQCEEACSKTFFKEEDREKsciritetegGYAINVCNQCGECIDVCPTGAITRDANGVVmiNKKLCVGCLMCVG 87

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2485681954 100 ICPAEIISLPGKAEKPKKeiiipqepiavtkdCVACGVCVPECPVDAISIED 151
Cdd:cd16372    88 FCPEGAMFKHEDYPEPFK--------------CIACGICVKACPTGALELVE 125
PRK05888 PRK05888
NADH-quinone oxidoreductase subunit NuoI;
159-210 1.33e-06

NADH-quinone oxidoreductase subunit NuoI;


Pssm-ID: 235637 [Multi-domain]  Cd Length: 164  Bit Score: 47.95  E-value: 1.33e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2485681954 159 KCIYCTVCSQTCPWNAIFVAGKLPQKRQKTIKSFTVNEEECIGCEKCVEACP 210
Cdd:PRK05888   59 RCIACKLCAAICPADAITIEAAEREDGRRRTTRYDINFGRCIFCGFCEEACP 110
NapF COG1145
Ferredoxin [Energy production and conversion];
62-247 1.61e-06

Ferredoxin [Energy production and conversion];


Pssm-ID: 440760 [Multi-domain]  Cd Length: 238  Bit Score: 48.95  E-value: 1.61e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954  62 KCDLDGACAKACPVGIKKVDDRFPYSKGHCVLCEKCVDICPAEIISLPGKAEKPKKEIIIPQEPIAVTKDCVACGVCVPE 141
Cdd:COG1145    47 LLPIIGILAKEAFDALKDVLGILGAIVIGIGAGEIVRVGIAAADLNLKAVALVLLLALAVAGAAKRLIISAVKLVAGLVV 126

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 142 CPVDAISIEDIAVIDTDKCIYCTVCSQTCPWNAIFVAGKLPQKRQKTIKSFTVNEEECIGCEKCVEACPGSMIEY-NGEA 220
Cdd:COG1145   127 AAGEVLLVIAAALAEAGLAILGAAAPVDALAISGGKKIEEELKIAIKKAKAVIDAEKCIGCGLCVKVCPTGAIRLkDGKP 206

                         170       180
                  ....*....|....*....|....*..
gi 2485681954 221 LGVKLPEACPACGLCVESCPVEVISLE 247
Cdd:COG1145   207 QIVVDPDKCIGCGACVKVCPVGAISLE 233
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 265-327 1.69e-06

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 45.12  E-value: 1.69e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2485681954 265 EEKCAYCGPCAIKCPTGAIKVVNPKGLELPSRNktekaneFAMCIRCGACAMKCPTGALKMGK 327
Cdd:COG1143     1 EDKCIGCGLCVRVCPVDAITIEDGEPGKVYVID-------PDKCIGCGLCVEVCPTGAISMTP 56
PreA COG1146
NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...
 152-210 1.78e-06

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];


Pssm-ID: 440761 [Multi-domain]  Cd Length: 67  Bit Score: 45.09  E-value: 1.78e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2485681954 152 IAVIDTDKCIYCTVCSQTCPWNAIFVAGklpqkrqKTIKSFTVNEEECIGCEKCVEACP 210
Cdd:COG1146     2 MPVIDTDKCIGCGACVEVCPVDVLELDE-------EGKKALVINPEECIGCGACELVCP 53
PorD COG1144
Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...
 193-249 1.97e-06

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit [Energy production and conversion]; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit is part of the Pathway/BioSystem: Pyruvate oxidation


Pssm-ID: 440759 [Multi-domain]  Cd Length: 84  Bit Score: 45.43  E-value: 1.97e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2485681954 193 TVNEEECIGCEKCVEACP-GSMIEYNGEALGVKlPEACPACGLCVESCPVEVISLEVE 249
Cdd:COG1144    26 VVDEDKCIGCGLCWIVCPdGAIRVDDGKYYGID-YDYCKGCGICAEVCPVKAIEMVPE 82
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
226-293 2.00e-06

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 45.11  E-value: 2.00e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2485681954 226 PEACPACGLCVESCPVEVISLEVEYASAKPvtdeglvwseEKCAYCGPCAIKCPTGAIKVVNPKGLEL 293
Cdd:COG2768    10 EEKCIGCGACVKVCPVGAISIEDGKAVIDP----------EKCIGCGACIEVCPVGAIKIEWEEDEEF 67
PRK13984 PRK13984
putative oxidoreductase; Provisional
 303-363 2.03e-06

putative oxidoreductase; Provisional


Pssm-ID: 172486 [Multi-domain]  Cd Length: 604  Bit Score: 49.77  E-value: 2.03e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2485681954 303 NEFAMCIRCGACAMKCPTGALKMGKMVHEGKEYARVEFSPAL----CNECGECVDVCPQKTLELT 363
Cdd:PRK13984   42 NDWEKCIGCGTCSKICPTDAITMVEVPDLPQEYGKKPQRPVIdygrCSFCALCVDICTTGSLKMT 106
DMSOR_beta_like cd16372
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 195-325 2.07e-06

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319894 [Multi-domain]  Cd Length: 125  Bit Score: 46.56  E-value: 2.07e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 195 NEEECIGCEKCVEACPG----------SMIEYNGEALGVKlPEACPACGLCVESCPVEVISleveyasakpVTDEGLVW- 263
Cdd:cd16372     6 DPEKCIGCLQCEEACSKtffkeedrekSCIRITETEGGYA-INVCNQCGECIDVCPTGAIT----------RDANGVVMi 74

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2485681954 264 SEEKCAYCGPCAIKCPTGAIKvvnpkglelpsrnKTEKANEFAMCIRCGACAMKCPTGALKM 325
Cdd:cd16372    75 NKKLCVGCLMCVGFCPEGAMF-------------KHEDYPEPFKCIACGICVKACPTGALEL 123
NapF COG1145
Ferredoxin [Energy production and conversion];
68-183 2.14e-06

Ferredoxin [Energy production and conversion];


Pssm-ID: 440760 [Multi-domain]  Cd Length: 238  Bit Score: 48.57  E-value: 2.14e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954  68 ACAKACPVGIKKVDDRFPYSKGHCVLCEKCVDICPAEIISLPGKAEKPKKEIIIPQEPIAVTKDCVACGVCVPECPVDAI 147
Cdd:COG1145   120 LVAGLVVAAGEVLLVIAAALAEAGLAILGAAAPVDALAISGGKKIEEELKIAIKKAKAVIDAEKCIGCGLCVKVCPTGAI 199

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 2485681954 148 SIED---IAVIDTDKCIYCTVCSQTCPWNAIFVAGKLPQ 183
Cdd:COG1145   200 RLKDgkpQIVVDPDKCIGCGACVKVCPVGAISLEPKEIE 238
IorA COG4231
TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...
 153-220 2.17e-06

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];


Pssm-ID: 443375 [Multi-domain]  Cd Length: 76  Bit Score: 45.03  E-value: 2.17e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2485681954 153 AVIDTDKCIYCTVCSQTCPWNAIFVAGKlpqkrqktikSFTVNEEECIGCEKCVEACPGSMIEYNGEA 220
Cdd:COG4231    17 YVIDEDKCTGCGACVKVCPADAIEEGDG----------KAVIDPDLCIGCGSCVQVCPVDAIKLEKRV 74
DMSOR_beta_like cd16372
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 55-177 2.18e-06

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319894 [Multi-domain]  Cd Length: 125  Bit Score: 46.56  E-value: 2.18e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954  55 KLVFNGSKCDLDGACAKACPVGIKKVDDR-----------FPYSKGHCVLCEKCVDICPAEIISlpgkaeKPKKEIIIPQ 123
Cdd:cd16372     2 LLVTDPEKCIGCLQCEEACSKTFFKEEDReksciriteteGGYAINVCNQCGECIDVCPTGAIT------RDANGVVMIN 75

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2485681954 124 EpiavtKDCVACGVCVPECPVDAISIEDiAVIDTDKCIYCTVCSQTCPWNAIFV 177
Cdd:cd16372    76 K-----KLCVGCLMCVGFCPEGAMFKHE-DYPEPFKCIACGICVKACPTGALEL 123
DMSOR_beta_like cd16373
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 90-210 2.20e-06

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319895 [Multi-domain]  Cd Length: 154  Bit Score: 47.25  E-value: 2.20e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954  90 HCVLCEKCVDICPAEIISlPGKAEKPKKEIIIPQEpIAVTKDCVACG-VCVPECPVDAISIED---------IAVIDTDK 159
Cdd:cd16373    15 LCIRCGLCVEACPTGVIQ-PAGLEDGLEGGRTPYL-DPREGPCDLCCdACVEVCPTGALRPLDleeqkvkmgVAVIDKDR 92

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2485681954 160 CI------YCTVCSQTCPWNAIFVAGKLPQKRQktiksfTVNEEECIGCEKCVEACP 210
Cdd:cd16373    93 CLawqggtDCGVCVEACPTEAIAIVLEDDVLRP------VVDEDKCVGCGLCEYVCP 143
napF TIGR00402
ferredoxin-type protein NapF; The gene codes for a ferredoxin-type cytosolic protein, NapF, of ...
 306-360 2.23e-06

ferredoxin-type protein NapF; The gene codes for a ferredoxin-type cytosolic protein, NapF, of the periplasmic nitrate reductase system, as in Escherichia coli. NapF interacts with the catalytic subunit, NapA, and may be an accessory protein for NapA maturation. [Energy metabolism, Electron transport]


Pssm-ID: 273060 [Multi-domain]  Cd Length: 101  Bit Score: 45.71  E-value: 2.23e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2485681954 306 AMCIRCGACAMKCPTGALKMGKmvhegKEYARVEFSPALCNECGECVDVCPQKTL 360
Cdd:TIGR00402  34 AVCTRCGECASACENNILQLGQ-----QGQPTVEFDNAECDFCGKCAEACPTNAF 83
PorD COG1144
Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...
 102-175 2.26e-06

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit [Energy production and conversion]; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit is part of the Pathway/BioSystem: Pyruvate oxidation


Pssm-ID: 440759 [Multi-domain]  Cd Length: 84  Bit Score: 45.43  E-value: 2.26e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2485681954 102 PAEIISLPGKAEKPKKEIIIPQEPIAVTKDCVACGVCVPECPVDAISIEDI--AVIDTDKCIYCTVCSQTCPWNAI 175
Cdd:COG1144     2 QGGAITEPGGTAAYKTGGWRVERPVVDEDKCIGCGLCWIVCPDGAIRVDDGkyYGIDYDYCKGCGICAEVCPVKAI 77
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 226-285 2.27e-06

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 44.74  E-value: 2.27e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 226 PEACPACGLCVESCPVEVISLEVEYASAKPVTDeglvwsEEKCAYCGPCAIKCPTGAIKV 285
Cdd:COG1143     1 EDKCIGCGLCVRVCPVDAITIEDGEPGKVYVID------PDKCIGCGLCVEVCPTGAISM 54
PRK09898 PRK09898
ferredoxin-like protein;
33-102 2.46e-06

ferredoxin-like protein;


Pssm-ID: 182135 [Multi-domain]  Cd Length: 208  Bit Score: 47.91  E-value: 2.46e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2485681954  33 TCIQCFS--CATACPTGA--LVEKDGKLVFNGSKCDLDGACAKACPVGIKKVDDRFPYSkGHCVLCEKCVDICP 102
Cdd:PRK09898  122 TCRQCKEpqCMNVCPIGAitWQQKEGCITVDHKRCIGCSACTTACPWMMATVNTESKKS-SKCVLCGECANACP 194
NapH COG0348
Polyferredoxin NapH [Energy production and conversion];
155-216 2.77e-06

Polyferredoxin NapH [Energy production and conversion];


Pssm-ID: 440117 [Multi-domain]  Cd Length: 263  Bit Score: 48.52  E-value: 2.77e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2485681954 155 IDTDKCIYCTVCSQTCPWNAIFVAGKLPQkrqktiksftvneEECIGCEKCVEACPGSMIEY 216
Cdd:COG0348   207 YDRGDCIDCGLCVKVCPMGIDIRKGEINQ-------------SECINCGRCIDACPKDAIRF 255
PRK13795 PRK13795
hypothetical protein; Provisional
 198-244 2.88e-06

hypothetical protein; Provisional


Pssm-ID: 237510 [Multi-domain]  Cd Length: 636  Bit Score: 49.22  E-value: 2.88e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2485681954 198 ECIGCEKCVEACPGSMIEYNGEALGVKL-PEACPACGLCVESCPVEVI 244
Cdd:PRK13795  582 ECVGCGVCVGACPTGAIRIEEGKRKISVdEEKCIHCGKCTEVCPVVKY 629
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
34-82 3.49e-06

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 44.34  E-value: 3.49e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 2485681954  34 CIQCFSCATACPTGALVEKDGKLVFNGSKCDLDGACAKACPVGIKKVDD 82
Cdd:COG2768    13 CIGCGACVKVCPVGAISIEDGKAVIDPEKCIGCGACIEVCPVGAIKIEW 61
RnfB COG2878
Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and ...
 67-171 3.74e-06

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase


Pssm-ID: 442125 [Multi-domain]  Cd Length: 254  Bit Score: 48.07  E-value: 3.74e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954  67 GACAKACPVG-IKKVDDRFP-YSKGHCVLCEKCVDICPAEIISLpgkAEKPKKEIIIPQEPIAVTKDCVAC--GVCVPEC 142
Cdd:COG2878   143 GDCIKACPFDaIVGAAKGMHtVDEDKCTGCGLCVEACPVDCIEM---VPVSPTVVVSSWDKGKAVRKVVGCigLCCKKCC 219

                          90       100
                  ....*....|....*....|....*....
gi 2485681954 143 PVDAISIEDIAVIDTDKCIYCTVCSQTCP 171
Cdd:COG2878   220 PAAAITVNNLAAIIDYKKCTCCGCCEKCC 248
NapF_like cd10564
NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, ...
 197-325 3.75e-06

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, the iron-sulfur subunit of periplasmic nitrate reductase. The periplasmic nitrate reductase NapABC of Escherichia coli likely functions during anaerobic growth in low-nitrate environments; napF operon expression is activated by cyclic AMP receptor protein (Crp). NapF is a subfamily of the beta subunit of DMSO reductase (DMSOR) family. DMSOR family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319886 [Multi-domain]  Cd Length: 139  Bit Score: 46.08  E-value: 3.75e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 197 EECIGCEKCVEACPGSMIEyNGEAlgvKLPE------ACPACGLCVESCPVEVISLEVEYA-SAKPVTDEG-LVWSEekc 268
Cdd:cd10564    13 DLCTRCGDCVEACPEGIIV-RGDG---GFPEldfsrgECTFCGACAEACPEGALDPAREAPwPLRAEIGDScLALQG--- 85

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2485681954 269 AYCGPCAIKCPTGAIKVV-NPKGLELPSRNktekaneFAMCIRCGACAMKCPTGALKM 325
Cdd:cd10564    86 VECRSCQDACPTQAIRFRpRLGGIALPELD-------ADACTGCGACVSVCPVGAITL 136
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 34-81 4.05e-06

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 44.27  E-value: 4.05e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2485681954  34 CIQCFSCATACPTGALVEKDGKLVFNGSKCDLDGACAKACPVGIKKVD 81
Cdd:COG2221    17 CIGCGLCVAVCPTGAISLDDGKLVIDEEKCIGCGACIRVCPTGAIKGE 64
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 308-362 4.18e-06

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 43.95  E-value: 4.18e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2485681954 308 CIRCGACAMKCPTGALKMGkmvhegkEYARVEFSPALCNECGECVDVCPQKTLEL 362
Cdd:COG1149    13 CIGCGLCVEVCPEGAIKLD-------DGGAPVVDPDLCTGCGACVGVCPTGAITL 60
NapH COG0348
Polyferredoxin NapH [Energy production and conversion];
4-49 4.49e-06

Polyferredoxin NapH [Energy production and conversion];


Pssm-ID: 440117 [Multi-domain]  Cd Length: 263  Bit Score: 47.75  E-value: 4.49e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 2485681954   4 ISIQEDACLVCNACAKACPTEaIEIA----PFKTCIQCFSCATACPTGAL 49
Cdd:COG0348   205 VRYDRGDCIDCGLCVKVCPMG-IDIRkgeiNQSECINCGRCIDACPKDAI 253
PreA COG1146
NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...
 91-156 4.64e-06

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];


Pssm-ID: 440761 [Multi-domain]  Cd Length: 67  Bit Score: 43.93  E-value: 4.64e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2485681954  91 CVLCEKCVDICPAEIISLPGKAEKPKkeiiipqepIAVTKDCVACGVCVPECPVDAISIEDIAVID 156
Cdd:COG1146    10 CIGCGACVEVCPVDVLELDEEGKKAL---------VINPEECIGCGACELVCPVGAITVEDDEPEE 66
PRK00783 PRK00783
DNA-directed RNA polymerase subunit D; Provisional
 196-249 4.68e-06

DNA-directed RNA polymerase subunit D; Provisional


Pssm-ID: 234837 [Multi-domain]  Cd Length: 263  Bit Score: 47.57  E-value: 4.68e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2485681954 196 EEECIGCEKCVEACPGSMIEYNGEALGVKLPEACPACGLCVESCPVEVISLEVE 249
Cdd:PRK00783  168 SEDCDECEKCVEACPRGVLELKEGKLVVTDLLNCSLCKLCERACPGKAIRVSDD 221
PRK12769 PRK12769
putative oxidoreductase Fe-S binding subunit; Reviewed
 11-108 4.84e-06

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183733 [Multi-domain]  Cd Length: 654  Bit Score: 48.59  E-value: 4.84e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954  11 CLVCNACAKACPTEAIE-------------IAPFK--------TCIQC--FSCATACPTGALVEKDGKLVFNGSKCDLDG 67
Cdd:PRK12769   12 CLGCHACEIACVMAHNDeqhvlsqhhfhprITVIKhqqqrsavTCHHCedAPCARSCPNGAISHVDDSIQVNQQKCIGCK 91

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2485681954  68 ACAKACPVGIKKV------DDRFPYSKGHCVLCE------KCVDICPAEIISL 108
Cdd:PRK12769   92 SCVVACPFGTMQIvltpvaAGKVKATAHKCDLCAgrengpACVENCPADALQL 144
PreA COG1146
NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...
 226-292 4.97e-06

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];


Pssm-ID: 440761 [Multi-domain]  Cd Length: 67  Bit Score: 43.93  E-value: 4.97e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2485681954 226 PEACPACGLCVESCPVEVISLEVEYASAKPVtdeglvwSEEKCAYCGPCAIKCPTGAIKVVNPKGLE 292
Cdd:COG1146     7 TDKCIGCGACVEVCPVDVLELDEEGKKALVI-------NPEECIGCGACELVCPVGAITVEDDEPEE 66
HybA COG0437
Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and ...
 190-328 5.02e-06

Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and conversion];


Pssm-ID: 440206 [Multi-domain]  Cd Length: 184  Bit Score: 46.48  E-value: 5.02e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 190 KSFTVNEEECIGCEKCVEAC------PGSM------IEYNGEALGVK---LPEACPACG--LCVESCPVEVISleveyas 252
Cdd:COG0437     6 YGMVIDLTKCIGCRACVVACkeennlPVGVtwrrvrRYEEGEFPNVEwlfVPVLCNHCDdpPCVKVCPTGATY------- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 253 akpVTDEGLV-WSEEKCAYCGPCAIKCPTGAIKVVnpkglelPSRNKTEKanefamCIRCG---------ACAMKCPTGA 322
Cdd:COG0437    79 ---KREDGIVlVDYDKCIGCRYCVAACPYGAPRFN-------PETGVVEK------CTFCAdrldegllpACVEACPTGA 142


                  ....*.
gi 2485681954 323 LKMGKM 328
Cdd:COG0437   143 LVFGDL 148
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
307-364 6.01e-06

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 48.32  E-value: 6.01e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2485681954 307 MCIRCGACAMKCPTGALKMgkmvhegKEYARVEFSPALCNECGECVDVCPQKTLELTG 364
Cdd:COG1148   497 KCTGCGRCVEVCPYGAISI-------DEKGVAEVNPALCKGCGTCAAACPSGAISLKG 547
PorD COG1144
Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...
 262-325 6.18e-06

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit [Energy production and conversion]; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit is part of the Pathway/BioSystem: Pyruvate oxidation


Pssm-ID: 440759 [Multi-domain]  Cd Length: 84  Bit Score: 43.89  E-value: 6.18e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2485681954 262 VWSEEKCAYCGPCAIKCPTGAIKVVNPKGLELpsrnktekanEFAMCIRCGACAMKCPTGALKM 325
Cdd:COG1144    26 VVDEDKCIGCGLCWIVCPDGAIRVDDGKYYGI----------DYDYCKGCGICAEVCPVKAIEM 79
DMSOR_beta_like cd16372
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 160-247 6.30e-06

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319894 [Multi-domain]  Cd Length: 125  Bit Score: 45.02  E-value: 6.30e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 160 CIYCTVCSQTCPWNAIFvagklpqkrQKTIKSFTVNEEECIGCEKCVEACP-GSMIEYNGealgVKLPEACPACGLCVES 238
Cdd:cd16372    49 CNQCGECIDVCPTGAIT---------RDANGVVMINKKLCVGCLMCVGFCPeGAMFKHED----YPEPFKCIACGICVKA 115


                  ....*....
gi 2485681954 239 CPVEVISLE 247
Cdd:cd16372   116 CPTGALELV 124
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
153-210 6.54e-06

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 43.57  E-value: 6.54e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2485681954 153 AVIDTDKCIYCTVCSQTCPWNAIFVAGKlpqkrqktikSFTVNEEECIGCEKCVEACP 210
Cdd:COG2768     6 PYVDEEKCIGCGACVKVCPVGAISIEDG----------KAVIDPEKCIGCGACIEVCP 53
PRK13984 PRK13984
putative oxidoreductase; Provisional
 266-327 7.04e-06

putative oxidoreductase; Provisional


Pssm-ID: 172486 [Multi-domain]  Cd Length: 604  Bit Score: 48.22  E-value: 7.04e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2485681954 266 EKCAYCGPCAIKCPTGAIKVVNPKGLELPSRNKTEK-ANEFAMCIRCGACAMKCPTGALKMGK 327
Cdd:PRK13984   45 EKCIGCGTCSKICPTDAITMVEVPDLPQEYGKKPQRpVIDYGRCSFCALCVDICTTGSLKMTR 107
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
192-253 7.15e-06

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 43.57  E-value: 7.15e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2485681954 192 FTVNEEECIGCEKCVEACPGSMIEYNGEALGVKlPEACPACGLCVESCPVEVISLEVEYASA 253
Cdd:COG2768     6 PYVDEEKCIGCGACVKVCPVGAISIEDGKAVID-PEKCIGCGACIEVCPVGAIKIEWEEDEE 66
NapF_like cd10564
NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, ...
 129-247 7.27e-06

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, the iron-sulfur subunit of periplasmic nitrate reductase. The periplasmic nitrate reductase NapABC of Escherichia coli likely functions during anaerobic growth in low-nitrate environments; napF operon expression is activated by cyclic AMP receptor protein (Crp). NapF is a subfamily of the beta subunit of DMSO reductase (DMSOR) family. DMSOR family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319886 [Multi-domain]  Cd Length: 139  Bit Score: 45.31  E-value: 7.27e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 129 TKDCVACGVCVPECPVDAISIED--IAVIDTDK--CIYCTVCSQTCPWNAIFVAGKLPQKRQKTIksftvnEEEC----- 199
Cdd:cd10564    12 LDLCTRCGDCVEACPEGIIVRGDggFPELDFSRgeCTFCGACAEACPEGALDPAREAPWPLRAEI------GDSClalqg 85

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2485681954 200 IGCEKCVEACPGSMIEYNGEALGVKLPE----ACPACGLCVESCPVEVISLE 247
Cdd:cd10564    86 VECRSCQDACPTQAIRFRPRLGGIALPEldadACTGCGACVSVCPVGAITLT 137
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
265-325 7.35e-06

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 47.93  E-value: 7.35e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2485681954 265 EEKCAYCGPCAIKCPTGAIKVVNPKglelpsrnkTEKANEfAMCIRCGACAMKCPTGALKM 325
Cdd:COG1148   495 PEKCTGCGRCVEVCPYGAISIDEKG---------VAEVNP-ALCKGCGTCAAACPSGAISL 545
PRK09898 PRK09898
ferredoxin-like protein;
9-80 7.38e-06

ferredoxin-like protein;


Pssm-ID: 182135 [Multi-domain]  Cd Length: 208  Bit Score: 46.37  E-value: 7.38e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954   9 DACLVCN--ACAKACPTEAIEIAP--------FKTCIQCFSCATACPTG-ALVEKDGKlvfNGSKCDLDGACAKACPVGI 77
Cdd:PRK09898  121 DTCRQCKepQCMNVCPIGAITWQQkegcitvdHKRCIGCSACTTACPWMmATVNTESK---KSSKCVLCGECANACPTGA 197


                  ...
gi 2485681954  78 KKV 80
Cdd:PRK09898  198 LKI 200
Nar1 COG4624
Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];
4-53 7.52e-06

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];


Pssm-ID: 443663 [Multi-domain]  Cd Length: 450  Bit Score: 47.71  E-value: 7.52e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2485681954   4 ISIQEDACLVCNACAKACPTEAIEIAPFKT------CIQCFSCATACPTGALVEKD 53
Cdd:COG4624    86 IIRDKEKCKNCYPCVRACPVKAIKVDDGKAeideekCISCGQCVAVCPFGAITEKS 141
IorA COG4231
TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...
 91-151 8.29e-06

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];


Pssm-ID: 443375 [Multi-domain]  Cd Length: 76  Bit Score: 43.49  E-value: 8.29e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2485681954  91 CVLCEKCVDICPAEIISlpgkaEKPKKEIIIPQEpiavtkdCVACGVCVPECPVDAISIED 151
Cdd:COG4231    24 CTGCGACVKVCPADAIE-----EGDGKAVIDPDL-------CIGCGSCVQVCPVDAIKLEK 72
PRK13795 PRK13795
hypothetical protein; Provisional
 306-356 8.52e-06

hypothetical protein; Provisional


Pssm-ID: 237510 [Multi-domain]  Cd Length: 636  Bit Score: 47.68  E-value: 8.52e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2485681954 306 AMCIRCGACAMKCPTGALKMGkmvhEGKeyARVEFSPALCNECGECVDVCP 356
Cdd:PRK13795  581 AECVGCGVCVGACPTGAIRIE----EGK--RKISVDEEKCIHCGKCTEVCP 625
PRK12769 PRK12769
putative oxidoreductase Fe-S binding subunit; Reviewed
 126-249 9.07e-06

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183733 [Multi-domain]  Cd Length: 654  Bit Score: 47.82  E-value: 9.07e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 126 IAVTKDCVACGVCVPECPVD------AISIED----IAVIDTDK------CIYC--TVCSQTCPWNAIFVAGKlpqkrqk 187
Cdd:PRK12769    6 MANSQQCLGCHACEIACVMAhndeqhVLSQHHfhprITVIKHQQqrsavtCHHCedAPCARSCPNGAISHVDD------- 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2485681954 188 tikSFTVNEEECIGCEKCVEACPGSMIEYNGEALGVKLPEA----CPACG------LCVESCPVEVISLEVE 249
Cdd:PRK12769   79 ---SIQVNQQKCIGCKSCVVACPFGTMQIVLTPVAAGKVKAtahkCDLCAgrengpACVENCPADALQLVTE 147
DMSOR_beta_like cd16369
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 190-327 9.19e-06

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319891 [Multi-domain]  Cd Length: 172  Bit Score: 45.84  E-value: 9.19e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 190 KSFTVNEEECIGCEKCVEACPG-------SMI--EYNGEALGVK-LPEACPACGL--CVESCPVEVISleveyasakpVT 257
Cdd:cd16369     2 KEFFIDPSRCIGCRACVAACREcgthrgkSMIhvDYIDRGESTQtAPTVCMHCEDptCAEVCPADAIK----------VT 71

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2485681954 258 DEGLVWS--EEKCAYCGPCAIKCPTGAIKVVnpkglelPSRNKTEKANefaMCI------RCGACAMKCPTGALKMGK 327
Cdd:cd16369    72 EDGVVQSalKPRCIGCSNCVNACPFGVPKYD-------EERNLMMKCD---MCYdrtsvgKAPMCASVCPSGALFYGT 139
NapH COG0348
Polyferredoxin NapH [Energy production and conversion];
131-185 9.64e-06

Polyferredoxin NapH [Energy production and conversion];


Pssm-ID: 440117 [Multi-domain]  Cd Length: 263  Bit Score: 46.59  E-value: 9.64e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2485681954 131 DCVACGVCVPECPVDaISIEDIAVIDTDkCIYCTVCSQTCPWNAIFVAGKLPQKR 185
Cdd:COG0348   211 DCIDCGLCVKVCPMG-IDIRKGEINQSE-CINCGRCIDACPKDAIRFSSRGEKTR 263
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 8-56 9.78e-06

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 42.81  E-value: 9.78e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2485681954   8 EDACLVCNACAKACPTEAIEIAPFKT----------CIQCFSCATACPTGALVEKDGKL 56
Cdd:COG1143     1 EDKCIGCGLCVRVCPVDAITIEDGEPgkvyvidpdkCIGCGLCVEVCPTGAISMTPFEL 59
Nar1 COG4624
Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];
34-102 9.97e-06

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];


Pssm-ID: 443663 [Multi-domain]  Cd Length: 450  Bit Score: 47.33  E-value: 9.97e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954  34 CIQCFSCATACPTGALVEKDGKLVFNGSKCDLDGACAKACPVG-IKKVDDRFPYSKGHCVLCEKCVDICP 102
Cdd:COG4624    64 CCVAISCIQVRGIIIIDKRGPSIIRDKEKCKNCYPCVRACPVKaIKVDDGKAEIDEEKCISCGQCVAVCP 133
FDH-O_like cd10560
beta subunit of formate dehydrogenase O (FDH-O) and similar proteins; This subfamily includes ...
 199-307 1.02e-05

beta subunit of formate dehydrogenase O (FDH-O) and similar proteins; This subfamily includes beta subunit of formate dehydrogenase family O (FDH-O), which is highly homologous to formate dehydrogenase N (FDH-N), a member of the DMSO reductase family. In E. coli three formate dehydrogenases are synthesized that are capable of oxidizing formate; Fdh-H, couples formate disproportionation to hydrogen and CO2, and is part of the cytoplasmically oriented formate hydrogenlyase complex, while FDH-N and FDH-O indicate their respective induction after growth with nitrate and oxygen. Little is known about FDH-O, although it shows formate oxidase activity during aerobic growth and is also synthesized during nitrate respiration, similar to FDH-N.


Pssm-ID: 319882 [Multi-domain]  Cd Length: 225  Bit Score: 46.23  E-value: 1.02e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 199 CIGCEK--CVEACPGSMIEYNGEALGVKLPEACPACGLCVESCPVEVISLEVEyasakpvtdEGLVWseeKCAYC----- 271
Cdd:cd10560    78 CKHCTDagCLEACPTGAIFRTEFGTVYIQPDICNGCGYCVAACPFGVIDRNEE---------TGRAH---KCTLCydrlk 145

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 2485681954 272 ---GP-CAIKCPTGAIKVVNPKGLELPSRNKTEKANEFAM 307
Cdd:cd10560   146 dglEPaCAKACPTGSIQFGPLEELRERARARVEQLHEQGV 185
PRK09898 PRK09898
ferredoxin-like protein;
138-210 1.03e-05

ferredoxin-like protein;


Pssm-ID: 182135 [Multi-domain]  Cd Length: 208  Bit Score: 45.98  E-value: 1.03e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2485681954 138 CVPECPVDAISIED---IAVIDTDKCIYCTVCSQTCPWNaifvagklpqkrQKTIKSFTVNEEECIGCEKCVEACP 210
Cdd:PRK09898  131 CMNVCPIGAITWQQkegCITVDHKRCIGCSACTTACPWM------------MATVNTESKKSSKCVLCGECANACP 194
Nar1 COG4624
Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];
6-82 1.06e-05

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];


Pssm-ID: 443663 [Multi-domain]  Cd Length: 450  Bit Score: 47.33  E-value: 1.06e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2485681954   6 IQEDACLVCNACAKACPTEAIEIAPFKTCIQCFSCATACPTGALVEKDGKLVFNGSKCDLDGACAKACPVGIKKVDD 82
Cdd:COG4624    65 CVAISCIQVRGIIIIDKRGPSIIRDKEKCKNCYPCVRACPVKAIKVDDGKAEIDEEKCISCGQCVAVCPFGAITEKS 141
DMSOR_beta_like cd10550
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 33-108 1.11e-05

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319872 [Multi-domain]  Cd Length: 130  Bit Score: 44.49  E-value: 1.11e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954  33 TCIQC--FSCATACPTGALV--EKDGKLVFNGSKCDLDGACAKACPVGIKKVDdrfpYSKGH---CVLCE---KCVDICP 102
Cdd:cd10550    48 VCRQCedAPCVEACPVGAISrdEETGAVVVDEDKCIGCGMCVEACPFGAIRVD----PETGKaikCDLCGgdpACVKVCP 123


                  ....*.
gi 2485681954 103 AEIISL 108
Cdd:cd10550   124 TGALEF 129
PRK12809 PRK12809
putative oxidoreductase Fe-S binding subunit; Reviewed
 198-339 1.11e-05

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183762 [Multi-domain]  Cd Length: 639  Bit Score: 47.33  E-value: 1.11e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 198 ECIGCEKCVEACPGS---------------MIEYNGEALGVKlPEACPAC--GLCVESCPVEVISLEveyasakpvtDEG 260
Cdd:PRK12809   11 ECIGCHACEIACAVAhnqenwplshsdfrpRIHVVGKGQAAN-PVACHHCnnAPCVTACPVNALTFQ----------SDS 79

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2485681954 261 LVWSEEKCAYCGPCAIKCPTGAIKVVNPKGLELPSRNKTEKANEfamcircgACAMKCPTGALKMgkMVHEGKEYARVE 339
Cdd:PRK12809   80 VQLDEQKCIGCKRCAIACPFGVVEMVDTIAQKCDLCNQRSSGTQ--------ACIEVCPTQALRL--MDDKGLQQIKVA 148
Fer4_7 pfam12838
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 308-356 1.15e-05

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 463724 [Multi-domain]  Cd Length: 51  Bit Score: 42.51  E-value: 1.15e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 2485681954 308 CIRCGACAMKCPTGALKMGKmVHEGKEYARVEFSPALCNECGECVDVCP 356
Cdd:pfam12838   1 CIGCGACVAACPVGAITLDE-VGEKKGTKTVVIDPERCVGCGACVAVCP 48
NuoI TIGR01971
NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of ...
 158-252 1.16e-05

NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of the NADH-quinone oxidoreductase complex I which generally couples NADH and ubiquinone oxidation/reduction in bacteria and mammalian mitochondria, but may act on NADPH and/or plastoquinone in cyanobacteria and plant chloroplasts. This model excludes "I" subunits from the closely related F420H2 dehydrogenase and formate hydrogenlyase complexes. [Energy metabolism, Electron transport]


Pssm-ID: 273902 [Multi-domain]  Cd Length: 122  Bit Score: 44.33  E-value: 1.16e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 158 DKCIYCTVCSQTCPWNAIFVAGKLPQKRQKTIKSFTVNEEECIgcekcveacpgsmieyngealgvklpeacpACGLCVE 237
Cdd:TIGR01971  43 EKCIGCTLCAAVCPADAIRVVPAEGEDGKRRLKFYEINFGRCI------------------------------FCGLCEE 92

                          90
                  ....*....|....*..
gi 2485681954 238 SCPVEVISL--EVEYAS 252
Cdd:TIGR01971  93 ACPTDAIVLtpEFELAT 109
Nar1 COG4624
Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];
226-357 1.18e-05

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];


Pssm-ID: 443663 [Multi-domain]  Cd Length: 450  Bit Score: 47.33  E-value: 1.18e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 226 PEACPACGLCVESCPVEVISLEVEYASAKPVTDEGLVWSEEKCAYCGPCAIKCPTGAIKVVNPKGLELPSRNKTEKANEF 305
Cdd:COG4624    11 CCIEEGDELLLLEEAERVLRIIILEALLPEHVDDDSACSCCPRCCLCCCCCCRCCVAISCIQVRGIIIIDKRGPSIIRDK 90

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2485681954 306 AMCIRCGACAMKCPTGALKMgkmvhegkEYARVEFSPALCNECGECVDVCPQ 357
Cdd:COG4624    91 EKCKNCYPCVRACPVKAIKV--------DDGKAEIDEEKCISCGQCVAVCPF 134
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 226-293 1.19e-05

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 42.79  E-value: 1.19e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2485681954 226 PEACPACGLCVESCPVEVISLEVEYAsakpvtdegLVWSEEKCAYCGPCAIKCPTGAIKVVNPKGLEL 293
Cdd:COG1149    10 EEKCIGCGLCVEVCPEGAIKLDDGGA---------PVVDPDLCTGCGACVGVCPTGAITLEEREAGKI 68
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 4-52 1.29e-05

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 42.73  E-value: 1.29e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2485681954   4 ISIQEDACLVCNACAKACPTEAIEIAPFK------TCIQCFSCATACPTGALVEK 52
Cdd:COG2221    10 PKIDEEKCIGCGLCVAVCPTGAISLDDGKlvideeKCIGCGACIRVCPTGAIKGE 64
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
232-292 1.38e-05

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 47.11  E-value: 1.38e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2485681954 232 CGL-CVESCPV-----EVISLEVEyaSAKPVTdeglvwSEEKCAYCGPCAIKCPTGAIKVVN-PKGLE 292
Cdd:PRK13409   17 CNYeCIKYCPVvrtgeETIEIDED--DGKPVI------SEELCIGCGICVKKCPFDAISIVNlPEELE 76
IorA COG4231
TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...
 226-290 1.39e-05

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];


Pssm-ID: 443375 [Multi-domain]  Cd Length: 76  Bit Score: 42.72  E-value: 1.39e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2485681954 226 PEACPACGLCVESCPVEVISLEveyasakpvtDEGLVWSEEKCAYCGPCAIKCPTGAIKVVNPKG 290
Cdd:COG4231    21 EDKCTGCGACVKVCPADAIEEG----------DGKAVIDPDLCIGCGSCVQVCPVDAIKLEKRVP 75
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 194-247 1.49e-05

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 42.35  E-value: 1.49e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2485681954 194 VNEEECIGCEKCVEACPGSMIEYNGEALGVKlPEACPACGLCVESCPVEVISLE 247
Cdd:COG2221    12 IDEEKCIGCGLCVAVCPTGAISLDDGKLVID-EEKCIGCGACIRVCPTGAIKGE 64
PRK08764 PRK08764
Rnf electron transport complex subunit RnfB;
196-246 1.57e-05

Rnf electron transport complex subunit RnfB;


Pssm-ID: 181550 [Multi-domain]  Cd Length: 135  Bit Score: 44.14  E-value: 1.57e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2485681954 196 EEECIGCEKCVEACPGSMIEYNGEALGVKLPEACPACGLCVESCPVEVISL 246
Cdd:PRK08764   84 EADCIGCTKCIQACPVDAIVGGAKHMHTVIAPLCTGCELCVPACPVDCIEL 134
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 262-327 1.60e-05

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 42.35  E-value: 1.60e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2485681954 262 VWSEEKCAYCGPCAIKCPTGAIKVVNPKGLELPSRnktekanefamCIRCGACAMKCPTGALKMGK 327
Cdd:COG2221    11 KIDEEKCIGCGLCVAVCPTGAISLDDGKLVIDEEK-----------CIGCGACIRVCPTGAIKGEK 65
HycB COG1142
Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];
154-288 1.62e-05

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];


Pssm-ID: 440757 [Multi-domain]  Cd Length: 138  Bit Score: 44.26  E-value: 1.62e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 154 VIDTDKCIYCTVCSQTCPWNAIFVAGKLPQKRQKTIKSFTVNE-EECIGCE--KCVEACPGSMIEYNGEALGVKlPEACP 230
Cdd:COG1142     6 IADPEKCIGCRTCEAACAVAHEGEEGEPFLPRIRVVRKAGVSApVQCRHCEdaPCAEVCPVGAITRDDGAVVVD-EEKCI 84

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2485681954 231 ACGLCVESCPVEVISLEVEYASAKPVtdeglvwseeKCAYCG------PCAIKCPTGAIKVVNP 288
Cdd:COG1142    85 GCGLCVLACPFGAITMVGEKSRAVAV----------KCDLCGgreggpACVEACPTGALRLVDV 138
DMSOR_beta_like cd16371
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 137-216 1.62e-05

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319893 [Multi-domain]  Cd Length: 140  Bit Score: 44.09  E-value: 1.62e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 137 VCVPECPVDAISIED--IAVIDTDKCIYCTVCSQTCPWNAIfvagKLPQKRQKTIKsftvneeeCIGCEK---------C 205
Cdd:cd16371    61 ACVKVCPTGAITKREdgIVVVDQDKCIGCGYCVWACPYGAP----QYNPETGKMDK--------CDMCVDrldegekpaC 128

                          90
                  ....*....|.
gi 2485681954 206 VEACPGSMIEY 216
Cdd:cd16371   129 VAACPTRALDF 139
DMSOR_beta_like cd16373
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 132-286 1.83e-05

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319895 [Multi-domain]  Cd Length: 154  Bit Score: 44.55  E-value: 1.83e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 132 CVACGVCVPECPVDAISIEDIA-----------VIDTDKCIYC-TVCSQTCPWNAIFVAGKLPQKRQktIKSFTVNEEEC 199
Cdd:cd16373    16 CIRCGLCVEACPTGVIQPAGLEdgleggrtpylDPREGPCDLCcDACVEVCPTGALRPLDLEEQKVK--MGVAVIDKDRC 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 200 IGcekcveacpgsmieYNGEAlgvklpeacpACGLCVESCPVEVISLEVEYASAKPVTDeglvwsEEKCAYCGPCAIKCP 279
Cdd:cd16373    94 LA--------------WQGGT----------DCGVCVEACPTEAIAIVLEDDVLRPVVD------EDKCVGCGLCEYVCP 143

                         170
                  ....*....|
gi 2485681954 280 T---GAIKVV 286
Cdd:cd16373   144 VeppKAIVVE 153
Nar1 COG4624
Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];
6-151 1.86e-05

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];


Pssm-ID: 443663 [Multi-domain]  Cd Length: 450  Bit Score: 46.56  E-value: 1.86e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954   6 IQEDACLVCNACAKACPTEAIEIAPFKTCIQCFSCATACPTGALVEKDGKLVFNGSKCDLDGACAKACPVGIKKVDDrfp 85
Cdd:COG4624    13 IEEGDELLLLEEAERVLRIIILEALLPEHVDDDSACSCCPRCCLCCCCCCRCCVAISCIQVRGIIIIDKRGPSIIRD--- 89

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2485681954  86 ysKGHCVLCEKCVDICPAEIIslpgKAEKPKKEIIipqepiavTKDCVACGVCVPECPVDAISIED 151
Cdd:COG4624    90 --KEKCKNCYPCVRACPVKAI----KVDDGKAEID--------EEKCISCGQCVAVCPFGAITEKS 141
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
308-370 2.06e-05

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 42.41  E-value: 2.06e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2485681954 308 CIRCGACAMKCPTGALKMGKMVHegkeyarvEFSPALCNECGECVDVCPQKTLELTGDDKMPL 370
Cdd:COG2768    13 CIGCGACVKVCPVGAISIEDGKA--------VIDPEKCIGCGACIEVCPVGAIKIEWEEDEEF 67
NapH COG0348
Polyferredoxin NapH [Energy production and conversion];
278-363 2.14e-05

Polyferredoxin NapH [Energy production and conversion];


Pssm-ID: 440117 [Multi-domain]  Cd Length: 263  Bit Score: 45.82  E-value: 2.14e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 278 CPTGAI-KVVNPKGLELPSRNKTEkanefamCIRCGACAMKCPTGaLKMGKMVHEGKEyarvefspalCNECGECVDVCP 356
Cdd:COG0348   188 CPYGAFqGLLSDLSTLRVRYDRGD-------CIDCGLCVKVCPMG-IDIRKGEINQSE----------CINCGRCIDACP 249


                  ....*..
gi 2485681954 357 QKTLELT 363
Cdd:COG0348   250 KDAIRFS 256
IorA COG4231
TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...
 34-76 2.37e-05

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];


Pssm-ID: 443375 [Multi-domain]  Cd Length: 76  Bit Score: 42.34  E-value: 2.37e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 2485681954  34 CIQCFSCATACPTGALVEKDGKLVFNGSKCDLDGACAKACPVG 76
Cdd:COG4231    24 CTGCGACVKVCPADAIEEGDGKAVIDPDLCIGCGSCVQVCPVD 66
FDH_beta_like cd16366
beta FeS subunits of formate dehydrogenase N (FDH-N) and similar proteins; This family ...
 9-76 2.45e-05

beta FeS subunits of formate dehydrogenase N (FDH-N) and similar proteins; This family contains beta FeS subunits of several dehydrogenases in the DMSO reductase superfamily, including formate dehydrogenase N (FDH-N), tungsten-containing formate dehydrogenase (W-FDH) and other similar proteins. FDH-N is a major component of nitrate respiration of Escherichia coli; it catalyzes the oxidation of formate to carbon dioxide, donating the electrons to a second substrate to a cytochrome. W-FDH contains a tungsten instead of molybdenum at the catalytic center and seems to be exclusively found in organisms such as hyperthermophilic archaea that live in extreme environments. It catalyzes the oxidation of formate to carbon dioxide, donating the electrons to a second substrate.


Pssm-ID: 319888 [Multi-domain]  Cd Length: 156  Bit Score: 43.93  E-value: 2.45e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954   9 DACLVCN--ACAKACPTEAIEIAPF-------KTCIQCFSCATACPTGA--LVEKDGKLvfngSKCD---------LDGA 68
Cdd:cd16366    68 DQCMHCTdaGCLAACPTGAIIRTETgtvvvdpETCIGCGYCVNACPFDIprFDEETGRV----AKCTlcydrisngLQPA 143


                  ....*...
gi 2485681954  69 CAKACPVG 76
Cdd:cd16366   144 CVKTCPTG 151
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
152-218 2.48e-05

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 46.39  E-value: 2.48e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2485681954 152 IAVIDTDKCIYCTVCSQTCPWNAIFVAGKlpqkrqKTIKsftVNEEECIGCEKCVEACPGSMIEYNG 218
Cdd:COG1148   490 VAEVDPEKCTGCGRCVEVCPYGAISIDEK------GVAE---VNPALCKGCGTCAAACPSGAISLKG 547
PRK10194 PRK10194
ferredoxin-type protein NapF;
132-251 3.38e-05

ferredoxin-type protein NapF;


Pssm-ID: 182296 [Multi-domain]  Cd Length: 163  Bit Score: 43.86  E-value: 3.38e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 132 CVACGVCVPECPVDAISIEDIAVIDTD----KCIYCTVCSQTCPwNAIFvagkLPQKRQKTIKSFTVNEE----ECIGCE 203
Cdd:PRK10194   36 CTRCDACINACENNILQRGAGGYPSVNfknnECSFCYACAQACP-ESLF----SPRHTRAWDLQFTIGDAclayQSVECR 110

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2485681954 204 KCVEACPGSMIEYNGEALGVKLPE----ACPACGLCVESCPVEVISLEVEYA 251
Cdd:PRK10194  111 RCQDSCEPMAIIFRPTLSGIYQPQlnsqLCNGCGACAASCPVSAITAEYLHA 162
Fer4_21 pfam14697
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 153-210 3.46e-05

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 434137 [Multi-domain]  Cd Length: 59  Bit Score: 41.11  E-value: 3.46e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2485681954 153 AVIDTDKCIYCTVCSQTCPWN---AIFVAGKlpqkrqktiKSFTVNEEECIGCEKCVEACP 210
Cdd:pfam14697   1 ARIDEDTCIGCGKCYIACPDTshqAIVGDGK---------RHHTVIEDECTGCNLCVSVCP 52
DMSOR_beta_like cd16373
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 199-320 3.47e-05

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319895 [Multi-domain]  Cd Length: 154  Bit Score: 43.78  E-value: 3.47e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 199 CIGCEKCVEACPGSMIEYNGEALGVKLPE---------AC-PACGLCVESCPVEVISLEVEYAS------AKPVTDEGLV 262
Cdd:cd16373    16 CIRCGLCVEACPTGVIQPAGLEDGLEGGRtpyldpregPCdLCCDACVEVCPTGALRPLDLEEQkvkmgvAVIDKDRCLA 95

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2485681954 263 WSEEKcaYCGPCAIKCPTGAIKVVNPKGLELPSRNKtekanefAMCIRCGACAMKCPT 320
Cdd:cd16373    96 WQGGT--DCGVCVEACPTEAIAIVLEDDVLRPVVDE-------DKCVGCGLCEYVCPV 144
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 34-76 3.48e-05

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 41.64  E-value: 3.48e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 2485681954  34 CIQCFSCATACPTGAL-VEKDGKLVFNGSKCDLDGACAKACPVG 76
Cdd:COG1149    13 CIGCGLCVEVCPEGAIkLDDGGAPVVDPDLCTGCGACVGVCPTG 56
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 91-159 3.50e-05

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 41.27  E-value: 3.50e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2485681954  91 CVLCEKCVDICPAEIISLPGKAEKPKKEIIipqepiavTKDCVACGVCVPECPVDAISIEDIAVIDTDK 159
Cdd:COG1143     4 CIGCGLCVRVCPVDAITIEDGEPGKVYVID--------PDKCIGCGLCVEVCPTGAISMTPFELAVEDR 64
NapF_like cd10564
NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, ...
 227-356 3.65e-05

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, the iron-sulfur subunit of periplasmic nitrate reductase. The periplasmic nitrate reductase NapABC of Escherichia coli likely functions during anaerobic growth in low-nitrate environments; napF operon expression is activated by cyclic AMP receptor protein (Crp). NapF is a subfamily of the beta subunit of DMSO reductase (DMSOR) family. DMSOR family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319886 [Multi-domain]  Cd Length: 139  Bit Score: 43.39  E-value: 3.65e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 227 EACPACGLCVESCPVEVIsleVEYASAKPVTDeglvWSEEKCAYCGPCAIKCPTGAIKVVNPKGLELP--------SRNK 298
Cdd:cd10564    13 DLCTRCGDCVEACPEGII---VRGDGGFPELD----FSRGECTFCGACAEACPEGALDPAREAPWPLRaeigdsclALQG 85

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2485681954 299 TEkanefamcirCGACAMKCPTGALKMgKMVHEGKeyARVEFSPALCNECGECVDVCP 356
Cdd:cd10564    86 VE----------CRSCQDACPTQAIRF-RPRLGGI--ALPELDADACTGCGACVSVCP 130
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
1-54 3.78e-05

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 41.64  E-value: 3.78e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954   1 MAGISIQEDACLVCNACAKACPTEAIEIAP------FKTCIQCFSCATACPTGALVEKDG 54
Cdd:COG2768     3 LGKPYVDEEKCIGCGACVKVCPVGAISIEDgkavidPEKCIGCGACIEVCPVGAIKIEWE 62
PRK05888 PRK05888
NADH-quinone oxidoreductase subunit NuoI;
132-175 3.94e-05

NADH-quinone oxidoreductase subunit NuoI;


Pssm-ID: 235637 [Multi-domain]  Cd Length: 164  Bit Score: 43.72  E-value: 3.94e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2485681954 132 CVACGVCVPECPVDAISIEDIAV-----------IDTDKCIYCTVCSQTCPWNAI 175
Cdd:PRK05888   60 CIACKLCAAICPADAITIEAAERedgrrrttrydINFGRCIFCGFCEEACPTDAI 114
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 262-327 4.67e-05

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 41.25  E-value: 4.67e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2485681954 262 VWSEEKCAYCGPCAIKCPTGAIKVVNPKGLELpsrnktekanEFAMCIRCGACAMKCPTGALKMGK 327
Cdd:COG1149     7 VIDEEKCIGCGLCVEVCPEGAIKLDDGGAPVV----------DPDLCTGCGACVGVCPTGAITLEE 62
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
34-77 4.77e-05

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 45.24  E-value: 4.77e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 2485681954  34 CIQCFSCATACPTGAL-VEKDGKLVFNGSKCDLDGACAKACPVGI 77
Cdd:COG1148   498 CTGCGRCVEVCPYGAIsIDEKGVAEVNPALCKGCGTCAAACPSGA 542
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 157-224 5.14e-05

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 40.88  E-value: 5.14e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2485681954 157 TDKCIYCTVCSQTCPWNAIFVAGKlpqkrqKTIKSFTVNEEECIGCEKCVEACPGSMIEYNGEALGVK 224
Cdd:COG1143     1 EDKCIGCGLCVRVCPVDAITIEDG------EPGKVYVIDPDKCIGCGLCVEVCPTGAISMTPFELAVE 62
NapF_like cd10564
NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, ...
 4-76 5.30e-05

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, the iron-sulfur subunit of periplasmic nitrate reductase. The periplasmic nitrate reductase NapABC of Escherichia coli likely functions during anaerobic growth in low-nitrate environments; napF operon expression is activated by cyclic AMP receptor protein (Crp). NapF is a subfamily of the beta subunit of DMSO reductase (DMSOR) family. DMSOR family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319886 [Multi-domain]  Cd Length: 139  Bit Score: 42.62  E-value: 5.30e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954   4 ISIQEDACLVCNACAKACPTEAIEIAPFK----------TC-----IQCFSCATACPTGAL-----VEKDGKLVFNGSKC 63
Cdd:cd10564    40 LDFSRGECTFCGACAEACPEGALDPAREApwplraeigdSClalqgVECRSCQDACPTQAIrfrprLGGIALPELDADAC 119

                          90
                  ....*....|...
gi 2485681954  64 DLDGACAKACPVG 76
Cdd:cd10564   120 TGCGACVSVCPVG 132
NapH COG0348
Polyferredoxin NapH [Energy production and conversion];
318-386 5.86e-05

Polyferredoxin NapH [Energy production and conversion];


Pssm-ID: 440117 [Multi-domain]  Cd Length: 263  Bit Score: 44.28  E-value: 5.86e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2485681954 318 CPTGALkMGKMVHEGKeyARVEFSPALCNECGECVDVCPqktlelTGDD--KMPLKGY-CVMCLKCIEACNK 386
Cdd:COG0348   188 CPYGAF-QGLLSDLST--LRVRYDRGDCIDCGLCVKVCP------MGIDirKGEINQSeCINCGRCIDACPK 250
PRK05888 PRK05888
NADH-quinone oxidoreductase subunit NuoI;
11-51 6.20e-05

NADH-quinone oxidoreductase subunit NuoI;


Pssm-ID: 235637 [Multi-domain]  Cd Length: 164  Bit Score: 42.95  E-value: 6.20e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2485681954  11 CLVCNACAKACPTEAIEI--AP--------------FKTCIQCFSCATACPTGALVE 51
Cdd:PRK05888   60 CIACKLCAAICPADAITIeaAEredgrrrttrydinFGRCIFCGFCEEACPTDAIVE 116
PRK07118 PRK07118
Fe-S cluster domain-containing protein;
6-77 6.24e-05

Fe-S cluster domain-containing protein;


Pssm-ID: 235941 [Multi-domain]  Cd Length: 280  Bit Score: 44.15  E-value: 6.24e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954   6 IQEDACLVCNACAKACPTEAIEIAPFKT----------------------CIQCFSCATACPTGALVEKDGKLVFNGSKC 63
Cdd:PRK07118  165 VDEDKCTGCGACVKACPRNVIELIPKSArvfvacnskdkgkavkkvcevgCIGCGKCVKACPAGAITMENNLAVIDQEKC 244

                          90
                  ....*....|....
gi 2485681954  64 DLDGACAKACPVGI 77
Cdd:PRK07118  245 TSCGKCVEKCPTKA 258
PRK14993 PRK14993
tetrathionate reductase subunit TtrB;
138-211 6.41e-05

tetrathionate reductase subunit TtrB;


Pssm-ID: 184955 [Multi-domain]  Cd Length: 244  Bit Score: 44.09  E-value: 6.41e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2485681954 138 CVPECPVDAI--SIEDIAVIDTDKCIYCTVCSQTCPWNAIFVAGKLPQKRQKTiksFTVNEEECIGCEKCVEACPG 211
Cdd:PRK14993  108 CVPVCPVQATfqREDGIVVVDNKRCVGCAYCVQACPYDARFINHETQTADKCT---FCVHRLEAGLLPACVESCVG 180
HycB COG1142
Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];
126-246 6.71e-05

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];


Pssm-ID: 440757 [Multi-domain]  Cd Length: 138  Bit Score: 42.34  E-value: 6.71e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 126 IAVTKDCVACGVCVPECPV------DAISIEDIAVIDTDK------CIYCTV--CSQTCPWNAIFVAGKLPQkrqktiks 191
Cdd:COG1142     6 IADPEKCIGCRTCEAACAVahegeeGEPFLPRIRVVRKAGvsapvqCRHCEDapCAEVCPVGAITRDDGAVV-------- 77

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2485681954 192 ftVNEEECIGCEKCVEACPGSMIEYNGEAlGVKLPEACPACG------LCVESCPVEVISL 246
Cdd:COG1142    78 --VDEEKCIGCGLCVLACPFGAITMVGEK-SRAVAVKCDLCGgreggpACVEACPTGALRL 135
NapF COG1145
Ferredoxin [Energy production and conversion];
24-210 6.98e-05

Ferredoxin [Energy production and conversion];


Pssm-ID: 440760 [Multi-domain]  Cd Length: 238  Bit Score: 43.94  E-value: 6.98e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954  24 EAIEIAPFKTCIQCFSCATACPTGALVEKDGKLVFNGSKCDLDGACAKACPVGIKKVDDRFPYSKGHCVLCEKCVDICPA 103
Cdd:COG1145    48 LPIIGILAKEAFDALKDVLGILGAIVIGIGAGEIVRVGIAAADLNLKAVALVLLLALAVAGAAKRLIISAVKLVAGLVVA 127

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 104 EIISLPGKAEKPKKEIIIPQEPIAVTKDCVACGVCVPECPVDAISIEDIAVIDTDKCIYCTVCSQTCPWNAIFVAGKLPQ 183
Cdd:COG1145   128 AGEVLLVIAAALAEAGLAILGAAAPVDALAISGGKKIEEELKIAIKKAKAVIDAEKCIGCGLCVKVCPTGAIRLKDGKPQ 207

                         170       180
                  ....*....|....*....|....*..
gi 2485681954 184 krqktiksFTVNEEECIGCEKCVEACP 210
Cdd:COG1145   208 --------IVVDPDKCIGCGACVKVCP 226
PRK12387 PRK12387
formate hydrogenlyase complex iron-sulfur subunit; Provisional
 226-314 7.20e-05

formate hydrogenlyase complex iron-sulfur subunit; Provisional


Pssm-ID: 183492 [Multi-domain]  Cd Length: 180  Bit Score: 43.10  E-value: 7.20e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 226 PEACPACGLCVESCPVEVISLEVEYASAKpvtdegLVWSEE--KCAYCGPCAIKCPTGAIKVVNPKGLELPSRNKTEKAN 303
Cdd:PRK12387   37 PQQCIGCAACVNACPSNALTVETDLATGE------LAWEFNlgRCIFCGRCEEVCPTAAIKLSQEFELAVWKKEDLLQQS 110

                          90
                  ....*....|.
gi 2485681954 304 EFAMCiRCGAC 314
Cdd:PRK12387  111 EFALC-NCRVC 120
PRK14028 PRK14028
pyruvate ferredoxin oxidoreductase subunit gamma/delta; Provisional
 151-215 7.31e-05

pyruvate ferredoxin oxidoreductase subunit gamma/delta; Provisional


Pssm-ID: 172522 [Multi-domain]  Cd Length: 312  Bit Score: 44.22  E-value: 7.31e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2485681954 151 DIAVIDTDKCIYCTVCSQTCPWNAIFVAGKL---PQKRQKTIKSFTVNEEECIGCEKCVEACPGSMIE 215
Cdd:PRK14028  240 DKPVIDHSKCIMCRKCWLYCPDDAIIEAWREaegPRGRKFRMKMIDFDYQYCKGCGVCAEVCPTGAIQ 307
RNAP_D cd07030
D subunit of Archaeal RNA polymerase; The D subunit of archaeal RNA polymerase (RNAP) is ...
 172-244 7.51e-05

D subunit of Archaeal RNA polymerase; The D subunit of archaeal RNA polymerase (RNAP) is involved in the assembly of RNAP subunits. RNAP is a large multi-subunit complex responsible for the synthesis of RNA. It is the principal enzyme of the transcription process, and is a final target in many regulatory pathways that control gene expression in all living cells. A single distinct RNAP complex is found in archaea, which may be responsible for the synthesis of all RNAs. The archaeal RNAP harbors homologues of all eukaryotic RNAP II subunits with two exceptions (RPB8 and RPB9). The 12 archaeal subunits are designated by letters and can be divided into three functional groups that are engaged in: (I) catalysis (A'/A", B'/B" or B); (II) assembly (L, N, D and P); and (III) auxiliary functions (F, E, H and K). The D subunit is equivalent to the RPB3 subunit of eukaryotic RNAP II. It contains two subdomains: one subdomain is similar the eukaryotic Rpb11/AC19/archaeal L subunit which is involved in dimerization, and the other is an inserted beta sheet subdomain. The assembly of the two largest archaeal RNAP subunits that provide most of the enzyme's catalytic functions depends on the presence of the archaeal D/L heterodimer.


Pssm-ID: 132908 [Multi-domain]  Cd Length: 259  Bit Score: 43.80  E-value: 7.51e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2485681954 172 WNAIFVAGKlpqkrqKTIKSFTVNEEeCIGCEKCVEACPGSMIEYNGEALGVKLPEACPACGLCVESCPVEVI 244
Cdd:cd07030   151 WQPTTACGY------KYYPVIEIDED-CDGCGKCVEECPRGVLELEEGKVVVEDLEDCSLCKLCERACDAGAI 216
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 232-292 8.15e-05

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 44.78  E-value: 8.15e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2485681954 232 CGL-CVESCPV-----EVISLEVEyaSAKPVTdeglvwSEEKCAYCGPCAIKCPTGAIKVVN-PKGLE 292
Cdd:COG1245    17 CNYeCIKYCPVnrtgkEAIEIDED--DGKPVI------SEELCIGCGICVKKCPFDAISIVNlPEELE 76
DMSOR_beta-like cd04410
Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta ...
 16-76 8.26e-05

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319870 [Multi-domain]  Cd Length: 136  Bit Score: 41.99  E-value: 8.26e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2485681954  16 ACAKACPTEAIEIAPF-------KTCIQCFSCATACPTGALVEKDGKLVfnGSKCDL---------DGACAKACPVG 76
Cdd:cd04410    57 PCVKACPTGAIYKDEDgivlideDKCIGCGSCVEACPYGAIVFDPEPGK--AVKCDLcgdrldeglEPACVKACPTG 131
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
91-151 8.43e-05

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 44.47  E-value: 8.43e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2485681954  91 CVLCEKCVDICPAEIISLpgkAEKPKKEIIipqePIAvtkdCVACGVCVPECPVDAISIED 151
Cdd:COG1148   498 CTGCGRCVEVCPYGAISI---DEKGVAEVN----PAL----CKGCGTCAAACPSGAISLKG 547
Fer4_10 pfam13237
4Fe-4S dicluster domain; This family includes proteins containing domains which bind to ...
 154-210 9.39e-05

4Fe-4S dicluster domain; This family includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. The structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 404174 [Multi-domain]  Cd Length: 56  Bit Score: 39.93  E-value: 9.39e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2485681954 154 VIDTDKCIYCTVCSQTCPWNAIFVAGKLPQKRQKTIKsftVNEEECIGCEKCVEACP 210
Cdd:pfam13237   3 VIDPDKCIGCGRCTAACPAGLTRVGAIVERLEGEAVR---IGVWKCIGCGACVEACP 56
PorD COG1144
Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...
 308-362 9.48e-05

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit [Energy production and conversion]; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit is part of the Pathway/BioSystem: Pyruvate oxidation


Pssm-ID: 440759 [Multi-domain]  Cd Length: 84  Bit Score: 40.81  E-value: 9.48e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2485681954 308 CIRCGACAMKCPTGALKMgkmvhegKEYARVEFSPALCNECGECVDVCPQKTLEL 362
Cdd:COG1144    32 CIGCGLCWIVCPDGAIRV-------DDGKYYGIDYDYCKGCGICAEVCPVKAIEM 79
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
97-149 1.00e-04

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 44.41  E-value: 1.00e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2485681954  97 CVDICP-----AEIISLPGKAEKPkkeiIIpQEPIavtkdCVACGVCVPECPVDAISI 149
Cdd:PRK13409   21 CIKYCPvvrtgEETIEIDEDDGKP----VI-SEEL-----CIGCGICVKKCPFDAISI 68
mauM_napG TIGR00397
MauM/NapG family ferredoxin-type protein; MauM is involved in methylamine utilization. NapG is ...
 228-283 1.05e-04

MauM/NapG family ferredoxin-type protein; MauM is involved in methylamine utilization. NapG is associated with nitrate reductase activity. The two proteins are highly similar. [Energy metabolism, Electron transport]


Pssm-ID: 129492 [Multi-domain]  Cd Length: 213  Bit Score: 42.98  E-value: 1.05e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2485681954 228 ACPACGLCVESCPVEVISLeVEYASAKPVTDEGLVWSEEKCAYCG--PCAIKCPTGAI 283
Cdd:TIGR00397  54 ACVRCGLCVEACPYDILSL-ASWSDPAPLGTPFFTPREVPCRMCKdiPCARACPTGAL 110
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 4-55 1.10e-04

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 40.10  E-value: 1.10e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2485681954   4 ISIQEDACLVCNACAKACPTEAIEIAPFKT-------CIQCFSCATACPTGALVEKDGK 55
Cdd:COG1149     6 PVIDEEKCIGCGLCVEVCPEGAIKLDDGGApvvdpdlCTGCGACVGVCPTGAITLEERE 64
PRK12809 PRK12809
putative oxidoreductase Fe-S binding subunit; Reviewed
 160-246 1.12e-04

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183762 [Multi-domain]  Cd Length: 639  Bit Score: 44.25  E-value: 1.12e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 160 CIYCT--VCSQTCPWNAIFVAGKlpqkrqktikSFTVNEEECIGCEKCVEACPGSMIEyngeaLGVKLPEACPACG---- 233
Cdd:PRK12809   56 CHHCNnaPCVTACPVNALTFQSD----------SVQLDEQKCIGCKRCAIACPFGVVE-----MVDTIAQKCDLCNqrss 120

                          90
                  ....*....|....*.
gi 2485681954 234 ---LCVESCPVEVISL 246
Cdd:PRK12809  121 gtqACIEVCPTQALRL 136
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 154-210 1.15e-04

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 40.03  E-value: 1.15e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2485681954 154 VIDTDKCIYCTVCSQTCPWNAIFVAGKLPqkrqktiksfTVNEEECIGCEKCVEACP 210
Cdd:COG2221    11 KIDEEKCIGCGLCVAVCPTGAISLDDGKL----------VIDEEKCIGCGACIRVCP 57
SIMIBI_bact_arch cd03110
bacterial and archaeal subfamily of SIMIBI; Uncharacterized bacterial and archaeal subfamily ...
 152-210 1.18e-04

bacterial and archaeal subfamily of SIMIBI; Uncharacterized bacterial and archaeal subfamily of SIMIBI superfamily. Proteins in this superfamily contain an ATP-binding domain and use energy from hydrolysis of ATP to transfer electron or ion. The specific function of this family is unknown.


Pssm-ID: 349764 [Multi-domain]  Cd Length: 246  Bit Score: 43.14  E-value: 1.18e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2485681954 152 IAVIDTDKCIYCTVCSQTCPWNAIFVAGKLPQkrqktiksftVNEEECIGCEKCVEACP 210
Cdd:cd03110    58 KAFIDQEKCIRCGNCERVCKFGAILEFFQKLI----------VDESLCEGCGACVIICP 106
NapF COG1145
Ferredoxin [Energy production and conversion];
197-366 1.26e-04

Ferredoxin [Energy production and conversion];


Pssm-ID: 440760 [Multi-domain]  Cd Length: 238  Bit Score: 43.17  E-value: 1.26e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 197 EECIGCEKCVEACPGSMIEYNGEALGVKLPEACPACGLCVESCPVEVISLEVEYASAKPVTDEGLVwSEEKCAYCGPCAI 276
Cdd:COG1145    74 IGIGAGEIVRVGIAAADLNLKAVALVLLLALAVAGAAKRLIISAVKLVAGLVVAAGEVLLVIAAAL-AEAGLAILGAAAP 152

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 277 KCPTGAIKVVNPKGLELPSRNKTEKANEFAMCIRCGACAMKCPTGALKMGKMVHEgkeyarVEFSPALCNECGECVDVCP 356
Cdd:COG1145   153 VDALAISGGKKIEEELKIAIKKAKAVIDAEKCIGCGLCVKVCPTGAIRLKDGKPQ------IVVDPDKCIGCGACVKVCP 226

                         170
                  ....*....|
gi 2485681954 357 QKTLELTGDD 366
Cdd:COG1145   227 VGAISLEPKE 236
PRK14028 PRK14028
pyruvate ferredoxin oxidoreductase subunit gamma/delta; Provisional
 254-325 1.34e-04

pyruvate ferredoxin oxidoreductase subunit gamma/delta; Provisional


Pssm-ID: 172522 [Multi-domain]  Cd Length: 312  Bit Score: 43.45  E-value: 1.34e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2485681954 254 KPVTDEglvwseEKCAYCGPCAIKCPTGAI-----KVVNPKGLELpsRNKTEKAnEFAMCIRCGACAMKCPTGALKM 325
Cdd:PRK14028  241 KPVIDH------SKCIMCRKCWLYCPDDAIieawrEAEGPRGRKF--RMKMIDF-DYQYCKGCGVCAEVCPTGAIQM 308
PorD COG1144
Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...
 31-76 1.46e-04

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit [Energy production and conversion]; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit is part of the Pathway/BioSystem: Pyruvate oxidation


Pssm-ID: 440759 [Multi-domain]  Cd Length: 84  Bit Score: 40.04  E-value: 1.46e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 2485681954  31 FKTCIQCFSCATACPTGALVEKDGK-LVFNGSKCDLDGACAKACPVG 76
Cdd:COG1144    29 EDKCIGCGLCWIVCPDGAIRVDDGKyYGIDYDYCKGCGICAEVCPVK 75
HybA COG0437
Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and ...
 16-76 1.53e-04

Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and conversion];


Pssm-ID: 440206 [Multi-domain]  Cd Length: 184  Bit Score: 42.24  E-value: 1.53e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2485681954  16 ACAKACPTEAIEIAPF-------KTCIQCFSCATACPTGA--LVEKDGKLVfngsKCDLDG---------ACAKACPVG 76
Cdd:COG0437    67 PCVKVCPTGATYKREDgivlvdyDKCIGCRYCVAACPYGAprFNPETGVVE----KCTFCAdrldegllpACVEACPTG 141
DMSOR_beta_like cd16370
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 195-247 1.56e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319892 [Multi-domain]  Cd Length: 131  Bit Score: 41.10  E-value: 1.56e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2485681954 195 NEEECIGCEKCVEACPGSMIEYNGEAlgvKLPEACPACGLCVESCPVEVISLE 247
Cdd:cd16370    81 DKEKCIGCGNCVKACIVGAIFWDEET---NKPIICIHCGYCARYCPHDVLAME 130
DMSOR_beta_like cd10550
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 160-247 1.58e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319872 [Multi-domain]  Cd Length: 130  Bit Score: 41.02  E-value: 1.58e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 160 CIYCT--VCSQTCPWNAIfvagklpqKRQKTIKSFTVNEEECIGCEKCVEACPGSMIEYNGEalgVKLPEACPACG---L 234
Cdd:cd10550    49 CRQCEdaPCVEACPVGAI--------SRDEETGAVVVDEDKCIGCGMCVEACPFGAIRVDPE---TGKAIKCDLCGgdpA 117

                          90
                  ....*....|...
gi 2485681954 235 CVESCPVEVISLE 247
Cdd:cd10550   118 CVKVCPTGALEFV 130
PRK09898 PRK09898
ferredoxin-like protein;
192-286 1.72e-04

ferredoxin-like protein;


Pssm-ID: 182135 [Multi-domain]  Cd Length: 208  Bit Score: 42.52  E-value: 1.72e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 192 FTVNEEECIGCE--KCVEACPGSMIEYNGEALGVKLPEA-CPACGLCVESCPVEVISLEVEYASAKpvtdeglvwseeKC 268
Cdd:PRK09898  116 LNYTADTCRQCKepQCMNVCPIGAITWQQKEGCITVDHKrCIGCSACTTACPWMMATVNTESKKSS------------KC 183

                          90
                  ....*....|....*...
gi 2485681954 269 AYCGPCAIKCPTGAIKVV 286
Cdd:PRK09898  184 VLCGECANACPTGALKII 201
PRK05888 PRK05888
NADH-quinone oxidoreductase subunit NuoI;
265-340 1.79e-04

NADH-quinone oxidoreductase subunit NuoI;


Pssm-ID: 235637 [Multi-domain]  Cd Length: 164  Bit Score: 41.79  E-value: 1.79e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2485681954 265 EEKCAYCGPCAIKCPTGAIKVV---NPKGlelpSRNKTEKANEFAMCIRCGACAMKCPTGALKMGKmVHEGKEYARVEF 340
Cdd:PRK05888   57 EERCIACKLCAAICPADAITIEaaeREDG----RRRTTRYDINFGRCIFCGFCEEACPTDAIVETP-DFELATETREEL 130
PRK13795 PRK13795
hypothetical protein; Provisional
 229-279 1.80e-04

hypothetical protein; Provisional


Pssm-ID: 237510 [Multi-domain]  Cd Length: 636  Bit Score: 43.44  E-value: 1.80e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2485681954 229 CPACGLCVESCPVEVISLEVEYASAKPvtdeglvwSEEKCAYCGPCAIKCP 279
Cdd:PRK13795  583 CVGCGVCVGACPTGAIRIEEGKRKISV--------DEEKCIHCGKCTEVCP 625
flavo_MJ0208 TIGR02700
archaeoflavoprotein, MJ0208 family; This model describes one of two paralogous families of ...
 32-74 1.93e-04

archaeoflavoprotein, MJ0208 family; This model describes one of two paralogous families of archaealflavoprotein. The other, described by TIGR02699 and typified by the partially characterized AF1518 of Archaeoglobus fulgidus, is a homodimeric FMN-containing flavoprotein that accepts electrons from ferredoxin and can transfer them to various oxidoreductases. The function of this protein family is unknown. [Unknown function, General]


Pssm-ID: 131747 [Multi-domain]  Cd Length: 234  Bit Score: 42.55  E-value: 1.93e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 2485681954  32 KTCIQCFSCATACPTGALVEKDGKLVFNGSKCDLDGACAKACP 74
Cdd:TIGR02700 148 KRCKGCGICVDACPRSAIDMVDGKAFIRLLKCVGCGKCKEACP 190
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 91-151 1.98e-04

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 39.33  E-value: 1.98e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2485681954  91 CVLCEKCVDICPAEIISLpgkaEKPKKEIIIPqepiavtKDCVACGVCVPECPVDAISIED 151
Cdd:COG1149    13 CIGCGLCVEVCPEGAIKL----DDGGAPVVDP-------DLCTGCGACVGVCPTGAITLEE 62
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
262-325 2.05e-04

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 39.33  E-value: 2.05e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2485681954 262 VWSEEKCAYCGPCAIKCPTGAIKVVNPKglelpsrnkteKANEFAMCIRCGACAMKCPTGALKM 325
Cdd:COG2768     7 YVDEEKCIGCGACVKVCPVGAISIEDGK-----------AVIDPEKCIGCGACIEVCPVGAIKI 59
IorA COG4231
TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...
 4-55 2.07e-04

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];


Pssm-ID: 443375 [Multi-domain]  Cd Length: 76  Bit Score: 39.64  E-value: 2.07e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2485681954   4 ISIQEDACLVCNACAKACPTEAIEIAPFK------TCIQCFSCATACPTGALVEKDGK 55
Cdd:COG4231    17 YVIDEDKCTGCGACVKVCPADAIEEGDGKavidpdLCIGCGSCVQVCPVDAIKLEKRV 74
IorA COG4231
TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...
 308-368 2.07e-04

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];


Pssm-ID: 443375 [Multi-domain]  Cd Length: 76  Bit Score: 39.64  E-value: 2.07e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2485681954 308 CIRCGACAMKCPTGALKMGKMVhegkeyarVEFSPALCNECGECVDVCPQKTLELTGDDKM 368
Cdd:COG4231    24 CTGCGACVKVCPADAIEEGDGK--------AVIDPDLCIGCGSCVQVCPVDAIKLEKRVPE 76
Fer4_21 pfam14697
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 194-242 2.09e-04

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 434137 [Multi-domain]  Cd Length: 59  Bit Score: 38.80  E-value: 2.09e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2485681954 194 VNEEECIGCEKCVEACPGSM---IEYNGEALGVKLPEACPACGLCVESCPVE 242
Cdd:pfam14697   3 IDEDTCIGCGKCYIACPDTShqaIVGDGKRHHTVIEDECTGCNLCVSVCPVD 54
NapF_like cd10564
NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, ...
 157-288 2.23e-04

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, the iron-sulfur subunit of periplasmic nitrate reductase. The periplasmic nitrate reductase NapABC of Escherichia coli likely functions during anaerobic growth in low-nitrate environments; napF operon expression is activated by cyclic AMP receptor protein (Crp). NapF is a subfamily of the beta subunit of DMSO reductase (DMSOR) family. DMSOR family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319886 [Multi-domain]  Cd Length: 139  Bit Score: 41.08  E-value: 2.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 157 TDKCIYCTVCSQTCPWNAIFV-AGKLPQkrqktiksFTVNEEECIGCEKCVEACPG---SMIEYNGEALGVKLPEACPA- 231
Cdd:cd10564    12 LDLCTRCGDCVEACPEGIIVRgDGGFPE--------LDFSRGECTFCGACAEACPEgalDPAREAPWPLRAEIGDSCLAl 83

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2485681954 232 ----CGLCVESCPVEVIS-LEVEYASAKPVTDEglvwseEKCAYCGPCAIKCPTGAIKVVNP 288
Cdd:cd10564    84 qgveCRSCQDACPTQAIRfRPRLGGIALPELDA------DACTGCGACVSVCPVGAITLTPL 139
Fer4_9 pfam13187
4Fe-4S dicluster domain;
307-360 2.52e-04

4Fe-4S dicluster domain;


Pssm-ID: 463801 [Multi-domain]  Cd Length: 50  Bit Score: 38.69  E-value: 2.52e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2485681954 307 MCIRCGACAMKCPTGAlkmgKMVHEGKEYARVEFSPALCNECGECVDVCPQKTL 360
Cdd:pfam13187   1 KCTGCGACVAACPAGA----IVPDLVGQTIRGDIAGLACIGCGACVDACPRGAI 50
PRK00783 PRK00783
DNA-directed RNA polymerase subunit D; Provisional
 126-177 2.62e-04

DNA-directed RNA polymerase subunit D; Provisional


Pssm-ID: 234837 [Multi-domain]  Cd Length: 263  Bit Score: 42.18  E-value: 2.62e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2485681954 126 IAVTKDCVACGVCVPECPVDAISIED--IAVIDTDKCIYCTVCSQTCPWNAIFV 177
Cdd:PRK00783  165 IEVSEDCDECEKCVEACPRGVLELKEgkLVVTDLLNCSLCKLCERACPGKAIRV 218
PorD COG1144
Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...
 154-215 2.78e-04

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit [Energy production and conversion]; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit is part of the Pathway/BioSystem: Pyruvate oxidation


Pssm-ID: 440759 [Multi-domain]  Cd Length: 84  Bit Score: 39.26  E-value: 2.78e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2485681954 154 VIDTDKCIYCTVCSQTCPWNAIfvagklpqkRQKTIKSFTVNEEECIGCEKCVEACPGSMIE 215
Cdd:COG1144    26 VVDEDKCIGCGLCWIVCPDGAI---------RVDDGKYYGIDYDYCKGCGICAEVCPVKAIE 78
HycB_like cd10554
HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a ...
 138-210 2.81e-04

HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a membrane-associated formate hydrogenlyase system (FHL-1) in Escherichia coli that breaks down formate, produced during anaerobic fermentation, to H2 and CO2. FHL-1 consists of formate dehydrogenase H (FDH-H) and the hydrogenase 3 complex (Hyd-3). HycB is thought to code for the [4Fe-4S] ferredoxin subunit of hydrogenase 3, which functions as an intermediate electron carrier protein between hydrogenase 3 and formate dehydrogenase. HydN codes for the [4Fe-4S] ferredoxin subunit of FDH-H; a hydN in-frame deletion mutation causes only weak reduction in hydrogenase activity, but loss of more than 60% of FDH-H activity. This pathway is only active at low pH and high formate concentrations, and is thought to provide a detoxification/de-acidification system countering the buildup of formate during fermentation.


Pssm-ID: 319876 [Multi-domain]  Cd Length: 149  Bit Score: 40.71  E-value: 2.81e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2485681954 138 CVPECPVDAISIEDIAV-IDTDKCIYCTVCSQTCPWNAIFVAGKLPQKRQKTIKSFTVNE--EECIGCEK---CVEACP 210
Cdd:cd10554    64 CANVCPVGAISQEDGVVqVDEERCIGCKLCVLACPFGAIEMAPTTVPGVDWERGPRAVAVkcDLCAGREGgpaCVEACP 142
NapH COG0348
Polyferredoxin NapH [Energy production and conversion];
86-150 2.85e-04

Polyferredoxin NapH [Energy production and conversion];


Pssm-ID: 440117 [Multi-domain]  Cd Length: 263  Bit Score: 42.36  E-value: 2.85e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2485681954  86 YSKGHCVLCEKCVDICPAEIIslpgkaekPKKEIIIPQEpiavtkdCVACGVCVPECPVDAISIE 150
Cdd:COG0348   207 YDRGDCIDCGLCVKVCPMGID--------IRKGEINQSE-------CINCGRCIDACPKDAIRFS 256
DMSOR_beta_like cd16371
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 16-76 3.29e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319893 [Multi-domain]  Cd Length: 140  Bit Score: 40.62  E-value: 3.29e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2485681954  16 ACAKACPTEAIEIAPF-------KTCIQCFSCATACPTGA--LVEKDGKLvfngSKCDL------DG---ACAKACPVG 76
Cdd:cd16371    61 ACVKVCPTGAITKREDgivvvdqDKCIGCGYCVWACPYGApqYNPETGKM----DKCDMcvdrldEGekpACVAACPTR 135
PRK12809 PRK12809
putative oxidoreductase Fe-S binding subunit; Reviewed
 11-210 3.43e-04

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183762 [Multi-domain]  Cd Length: 639  Bit Score: 42.71  E-value: 3.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954  11 CLVCNACAKAC---------PTEAIEIAP-----FK-------TCIQCFS--CATACPTGALVEKDGKLVFNGSKCDLDG 67
Cdd:PRK12809   12 CIGCHACEIACavahnqenwPLSHSDFRPrihvvGKgqaanpvACHHCNNapCVTACPVNALTFQSDSVQLDEQKCIGCK 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954  68 ACAKACPVGIKKVDDRFPYSkghCVLC-------EKCVDICPAEIISL---------------------PGKAEKPKKEI 119
Cdd:PRK12809   92 RCAIACPFGVVEMVDTIAQK---CDLCnqrssgtQACIEVCPTQALRLmddkglqqikvarqrktaagkASSDAQPSRSA 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 120 IIPQEPIAVTKDCVACG-----VCVPECPVDAISiediAVIDTDKCIYCTV---CSQTCPW-NAIFVAGKLPQKrQKTIK 190
Cdd:PRK12809  169 ALLPVNSRKGADKISASerkthFGEIYCGLDPQQ----ATYESDRCVYCAEkanCNWHCPLhNAIPDYIRLVQE-GKIIE 243

                         250       260
                  ....*....|....*....|
gi 2485681954 191 SFTVNEEECIGCEKCVEACP 210
Cdd:PRK12809  244 AAELCHQTSSLPEICGRVCP 263
COG1453 COG1453
Predicted oxidoreductase of the aldo/keto reductase family [General function prediction only];
307-358 3.79e-04

Predicted oxidoreductase of the aldo/keto reductase family [General function prediction only];


Pssm-ID: 441062 [Multi-domain]  Cd Length: 365  Bit Score: 42.11  E-value: 3.79e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2485681954 307 MCIRCGACaMKCPTGA-----------LKMGKMVHEGKE-YARVEFS--PALCNECGECVDVCPQK 358
Cdd:COG1453   282 FCTGCGYC-MPCPQGInipevfrlynlARAYGMREYAKErYNALGPGakASACIECGACEERCPQG 346
napF TIGR00402
ferredoxin-type protein NapF; The gene codes for a ferredoxin-type cytosolic protein, NapF, of ...
 34-74 3.93e-04

ferredoxin-type protein NapF; The gene codes for a ferredoxin-type cytosolic protein, NapF, of the periplasmic nitrate reductase system, as in Escherichia coli. NapF interacts with the catalytic subunit, NapA, and may be an accessory protein for NapA maturation. [Energy metabolism, Electron transport]


Pssm-ID: 273060 [Multi-domain]  Cd Length: 101  Bit Score: 39.54  E-value: 3.93e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 2485681954  34 CIQCFSCATACPTGALVEKDG---KLVFNGSKCDLDGACAKACP 74
Cdd:TIGR00402  36 CTRCGECASACENNILQLGQQgqpTVEFDNAECDFCGKCAEACP 79
PRK13795 PRK13795
hypothetical protein; Provisional
 343-384 4.20e-04

hypothetical protein; Provisional


Pssm-ID: 237510 [Multi-domain]  Cd Length: 636  Bit Score: 42.29  E-value: 4.20e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 2485681954 343 ALCNECGECVDVCPQKTLELTGDDK--MPLKGYCVMCLKCIEAC 384
Cdd:PRK13795  581 AECVGCGVCVGACPTGAIRIEEGKRkiSVDEEKCIHCGKCTEVC 624
DMSOR_beta_like cd16367
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 195-324 4.31e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319889 [Multi-domain]  Cd Length: 138  Bit Score: 39.98  E-value: 4.31e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 195 NEEECIGCEKCVEACPG-----SMIEYNGEALG-VKLPEACPAC--GLCVESCPVEVISLEveyasakpvtDEGLVWSEE 266
Cdd:cd16367    17 DLDRCIRCDNCEKACADthdghSRLDRNGLRFGnLLVPTACRHCvdPVCMIGCPTGAIHRD----------DGGEVVISD 86

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 267 KCAYCGPCAIKCPTGAIKVVnpkglelpsrnkteKANEFAMCIRCG--ACAMKCPTGALK 324
Cdd:cd16367    87 ACCGCGNCASACPYGAIQMV--------------RAVKCDLCAGYAgpACVSACPTGAAI 132
FDH_b_like cd10562
uncharacterized subfamily of beta subunit of formate dehydrogenase; This subfamily includes ...
 132-175 4.46e-04

uncharacterized subfamily of beta subunit of formate dehydrogenase; This subfamily includes the beta-subunit of formate dehydrogenases that are as yet uncharacterized. Members of the DMSO reductase family include formate dehydrogenase N and O (FDH-N, FDH-O) and tungsten-containing formate dehydrogenase (W-FDH) and other similar proteins. FDH-N, a major component of nitrate respiration of Escherichia coli, is involved in the major anaerobic respiratory pathway in the presence of nitrate, catalyzing the oxidation of formate to carbon dioxide at the expense of nitrate reduction to nitrite. It forms a heterotrimer; the alpha-subunit (FDH-G) is the catalytic site of formate oxidation and membrane-associated, incorporating a selenocysteine (SeCys) residue and a [4Fe/4S] cluster in addition to two bis-MGD cofactors, the beta subunit (FDH-H) contains four [4Fe/4S] clusters which transfer the electrons from the alpha subunit to the gamma-subunit (FDH-I), a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. W-FDH contains a tungsten instead of molybdenum at the catalytic center. This enzyme seems to be exclusively found in organisms such as hyperthermophilic archaea that live in extreme environments. It is a heterodimer of a large and a small subunit; the large subunit harbors the W site and one [4Fe-4S] center and the small subunit, containing three [4Fe-4S] clusters, functions to transfer electrons.


Pssm-ID: 319884 [Multi-domain]  Cd Length: 161  Bit Score: 40.36  E-value: 4.46e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2485681954 132 CVACG--VCVPECPVDAISIED--IAVIDTDKCIYCTVCSQTCPWNAI 175
Cdd:cd10562    70 CMHCTdaACVKVCPTGALYKTEngAVVVDEDKCIGCGYCVAACPFDVP 117
DMSOR_beta_like cd16370
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 192-325 4.50e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319892 [Multi-domain]  Cd Length: 131  Bit Score: 39.95  E-value: 4.50e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 192 FTVNEEECIGCEKCVEACPGSMIEYNG---EALGVKLP---------EACPACGL--CVESCPVEVIsleveyasaKPVT 257
Cdd:cd16370     4 RVKDMERCIGCYSCMLACSRRVHKSASlskSAIRVRTRggleggftvVVCRACEDppCAEACPTGAL---------EPRK 74

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2485681954 258 DEGLVWSEEKCAYCGPCAIKCPTGAIKVvnpkglelpsrnkTEKANEFAMCIRCGACAMKCPTGALKM 325
Cdd:cd16370    75 GGGVVLDKEKCIGCGNCVKACIVGAIFW-------------DEETNKPIICIHCGYCARYCPHDVLAM 129
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 97-149 4.58e-04

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 42.46  E-value: 4.58e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2485681954  97 CVDICP-----AEIISLPgkaEKPKKEIIipQEPIavtkdCVACGVCVPECPVDAISI 149
Cdd:COG1245    21 CIKYCPvnrtgKEAIEID---EDDGKPVI--SEEL-----CIGCGICVKKCPFDAISI 68
Fer4_7 pfam12838
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 132-174 4.84e-04

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 463724 [Multi-domain]  Cd Length: 51  Bit Score: 37.89  E-value: 4.84e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2485681954 132 CVACGVCVPECPVDAISIE--------DIAVIDTDKCIYCTVCSQTCPWNA 174
Cdd:pfam12838   1 CIGCGACVAACPVGAITLDevgekkgtKTVVIDPERCVGCGACVAVCPTGA 51
NapF_like cd10564
NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, ...
 308-384 4.94e-04

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, the iron-sulfur subunit of periplasmic nitrate reductase. The periplasmic nitrate reductase NapABC of Escherichia coli likely functions during anaerobic growth in low-nitrate environments; napF operon expression is activated by cyclic AMP receptor protein (Crp). NapF is a subfamily of the beta subunit of DMSO reductase (DMSOR) family. DMSOR family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319886 [Multi-domain]  Cd Length: 139  Bit Score: 39.92  E-value: 4.94e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 308 CIRCGACAMKCPTGALKMGkmvhEGKeYARVEFSPALCNECGECVDVCPQKTLELTGDDKMPLK---------GYCVMCL 378
Cdd:cd10564    15 CTRCGDCVEACPEGIIVRG----DGG-FPELDFSRGECTFCGACAEACPEGALDPAREAPWPLRaeigdsclaLQGVECR 89


                  ....*.
gi 2485681954 379 KCIEAC 384
Cdd:cd10564    90 SCQDAC 95
PRK09898 PRK09898
ferredoxin-like protein;
4-49 5.36e-04

ferredoxin-like protein;


Pssm-ID: 182135 [Multi-domain]  Cd Length: 208  Bit Score: 40.97  E-value: 5.36e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 2485681954   4 ISIQEDACLVCNACAKACP----TEAIEIAPFKTCIQCFSCATACPTGAL 49
Cdd:PRK09898  149 ITVDHKRCIGCSACTTACPwmmaTVNTESKKSSKCVLCGECANACPTGAL 198
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
91-161 5.41e-04

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 38.17  E-value: 5.41e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2485681954  91 CVLCEKCVDICPAEIISLpgkaEKPKKEIIipqepiavTKDCVACGVCVPECPVDAISIEDIAVIDTDKCI 161
Cdd:COG2768    13 CIGCGACVKVCPVGAISI----EDGKAVID--------PEKCIGCGACIEVCPVGAIKIEWEEDEEFQEKM 71
PRK12769 PRK12769
putative oxidoreductase Fe-S binding subunit; Reviewed
 268-366 5.45e-04

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183733 [Multi-domain]  Cd Length: 654  Bit Score: 42.04  E-value: 5.45e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 268 CAYC--GPCAIKCPTGAIKVVNpKGLELpsrnKTEKanefamCIRCGACAMKCPTGALkmgKMVHEGKEYARVEFSPALC 345
Cdd:PRK12769   56 CHHCedAPCARSCPNGAISHVD-DSIQV----NQQK------CIGCKSCVVACPFGTM---QIVLTPVAAGKVKATAHKC 121

                          90       100
                  ....*....|....*....|....*..
gi 2485681954 346 NECGE------CVDVCPQKTLELTGDD 366
Cdd:PRK12769  122 DLCAGrengpaCVENCPADALQLVTEQ 148
PRK08318 PRK08318
NAD-dependent dihydropyrimidine dehydrogenase subunit PreA;
152-210 6.53e-04

NAD-dependent dihydropyrimidine dehydrogenase subunit PreA;


Pssm-ID: 236237 [Multi-domain]  Cd Length: 420  Bit Score: 41.47  E-value: 6.53e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2485681954 152 IAVIDTDKCIYCTVCSQTCpWNAIFVAGKLPQKRQKTiksFTVNEEECIGCEKCVEACP 210
Cdd:PRK08318  336 YARIDQDKCIGCGRCYIAC-EDTSHQAIEWDEDGTRT---PEVIEEECVGCNLCAHVCP 390
DMSOR_beta_like cd16370
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 273-362 6.54e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319892 [Multi-domain]  Cd Length: 131  Bit Score: 39.56  E-value: 6.54e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 273 PCAIKCPTGAIKVVNPKGLELpsrnKTEKanefamCIRCGACAMKCPTGALKMgkmvHEGKEYarvefsPALCNECGECV 352
Cdd:cd16370    60 PCAEACPTGALEPRKGGGVVL----DKEK------CIGCGNCVKACIVGAIFW----DEETNK------PIICIHCGYCA 119

                          90
                  ....*....|
gi 2485681954 353 DVCPQKTLEL 362
Cdd:cd16370   120 RYCPHDVLAM 129
rnfC TIGR01945
electron transport complex, RnfABCDGE type, C subunit; The six subunit complex RnfABCDGE in ...
 290-358 7.98e-04

electron transport complex, RnfABCDGE type, C subunit; The six subunit complex RnfABCDGE in Rhodobacter capsulatus encodes an apparent NADH oxidoreductase responsible for electron transport to nitrogenase, necessary for nitrogen fixation. A closely related complex in E. coli, RsxABCDGE (Reducer of SoxR), reduces the 2Fe-2S-containing superoxide sensor SoxR, active as a transcription factor when oxidized. This family of putative NADH oxidoreductase complexes exists in many of the same species as the related NQR, a Na(+)-translocating NADH-quinone reductase, but is distinct. This model describes the C subunit. [Energy metabolism, Electron transport]


Pssm-ID: 273888 [Multi-domain]  Cd Length: 435  Bit Score: 41.17  E-value: 7.98e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2485681954 290 GLELPSRNKTEKANEFAmCIRCGACAMKCPTGALKMGKMVH-EGKEYARVEFSPAL-CNECGECVDVCPQK 358
Cdd:TIGR01945 348 GILALDKEETPESPEKP-CIRCGKCVQVCPMNLLPQQLNWLaLADEFDEAEEHNLMdCIECGCCSYVCPSN 417
PorD COG1144
Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...
 91-151 8.17e-04

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit [Energy production and conversion]; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit is part of the Pathway/BioSystem: Pyruvate oxidation


Pssm-ID: 440759 [Multi-domain]  Cd Length: 84  Bit Score: 38.11  E-value: 8.17e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2485681954  91 CVLCEKCVDICPAEIISlpgkaEKPKKEIIIPQEpiavtkDCVACGVCVPECPVDAISIED 151
Cdd:COG1144    32 CIGCGLCWIVCPDGAIR-----VDDGKYYGIDYD------YCKGCGICAEVCPVKAIEMVP 81
PRK05888 PRK05888
NADH-quinone oxidoreductase subunit NuoI;
82-148 8.66e-04

NADH-quinone oxidoreductase subunit NuoI;


Pssm-ID: 235637 [Multi-domain]  Cd Length: 164  Bit Score: 39.86  E-value: 8.66e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2485681954  82 DRFPYSKGHCVLCEKCVDICPAEIISLPGkAEKPKKEIIIPQEPIAVTKdCVACGVCVPECPVDAIS 148
Cdd:PRK05888   51 RRDPNGEERCIACKLCAAICPADAITIEA-AEREDGRRRTTRYDINFGR-CIFCGFCEEACPTDAIV 115
PsrB cd10551
polysulfide reductase beta (PsrB) subunit; This family includes the beta subunit of bacterial ...
 138-211 8.93e-04

polysulfide reductase beta (PsrB) subunit; This family includes the beta subunit of bacterial polysulfide reductase (PsrABC), an integral membrane-bound enzyme responsible for quinone-coupled reduction of polysulfides, a process important in extreme environments such as deep-sea vents and hot springs. Polysulfide reductase contains three subunits: a catalytic subunit PsrA, an electron transfer PsrB subunit and the hydrophobic transmembrane PsrC subunit. PsrB belongs to the DMSO reductase superfamily that contains [4Fe-4S] clusters which transfer the electrons from the A subunit to the hydrophobic integral membrane C subunit via the B subunit. In Shewanella oneidensis, which has highly diverse anaerobic respiratory pathways, PsrABC is responsible for H2S generation as well as its regulation via respiration of sulfur species. PsrB transfers electrons from PsrC (serving as quinol oxidase) to the catalytic subunit PsrA for reduction of corresponding electron acceptors. It has been shown that T. thermophilus polysulfide reductase could be a key energy-conserving enzyme of the respiratory chain, using polysulfide as the terminal electron acceptor and pumping protons across the membrane.


Pssm-ID: 319873 [Multi-domain]  Cd Length: 185  Bit Score: 39.82  E-value: 8.93e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 138 CVPECPVDAISIED--IAVIDTDKCIYCTVCSQTCPWNAIFVAGKLPQKRQKTIKSFTVNEEECIGCEK---------CV 206
Cdd:cd10551    61 CVKVCPTGATYKREdgIVLVDYDKCIGCRYCMAACPYGARYFNPEEPHEFGEVPVRPKGVVEKCTFCYHrldegllpaCV 140


                  ....*
gi 2485681954 207 EACPG 211
Cdd:cd10551   141 EACPT 145
PRK13795 PRK13795
hypothetical protein; Provisional
 267-319 9.26e-04

hypothetical protein; Provisional


Pssm-ID: 237510 [Multi-domain]  Cd Length: 636  Bit Score: 41.52  E-value: 9.26e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2485681954 267 KCAYCGPCAIKCPTGAIKVVNPKGLelpSRNKTEKanefamCIRCGACAMKCP 319
Cdd:PRK13795  582 ECVGCGVCVGACPTGAIRIEEGKRK---ISVDEEK------CIHCGKCTEVCP 625
DMSOR_beta-like cd04410
Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta ...
 4-106 9.33e-04

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319870 [Multi-domain]  Cd Length: 136  Bit Score: 39.29  E-value: 9.33e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954   4 ISIQEDACLVCNACAKACPTE-------------AIEIAPFK------TCIQCF--SCATACPTGALVE-KDGKLVFNGS 61
Cdd:cd04410     1 LVVDLDRCIGCGTCEVACKQEhglrpgpdwsrikVIEGGGLEraflpvSCMHCEdpPCVKACPTGAIYKdEDGIVLIDED 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2485681954  62 KCDLDGACAKACPVGIKKVDDRfPYSKGHCVLCEK---------CVDICPAEII 106
Cdd:cd04410    81 KCIGCGSCVEACPYGAIVFDPE-PGKAVKCDLCGDrldeglepaCVKACPTGAL 133
DMSOR_beta_like cd16374
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 194-327 9.44e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319896 [Multi-domain]  Cd Length: 139  Bit Score: 39.18  E-value: 9.44e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 194 VNEEECIGCEKCVEAC-------PGSMIEYNGEALGVklPEACPAC--GLCVESCPVEVISLEveyasakpvTDEGLVWS 264
Cdd:cd16374     3 VDPERCIGCRACEIACarehsgkPRISVEVVEDLASV--PVRCRHCedAPCMEVCPTGAIYRD---------EDGAVLVD 71

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2485681954 265 EEKCAYCGPCAIKCPTGAIKVVNPKGLELPSRNKTEKANEFAMcircGACAMKCPTGALKMGK 327
Cdd:cd16374    72 PDKCIGCGMCAMACPFGVPRFDPSLKVAVKCDLCIDRRREGKL----PACVEACPTGALKFGD 130
PRK00783 PRK00783
DNA-directed RNA polymerase subunit D; Provisional
 333-384 9.75e-04

DNA-directed RNA polymerase subunit D; Provisional


Pssm-ID: 234837 [Multi-domain]  Cd Length: 263  Bit Score: 40.64  E-value: 9.75e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2485681954 333 KEYARVEFSPaLCNECGECVDVCPQKTLELTGDDKMPLKGY-CVMCLKCIEAC 384
Cdd:PRK00783  160 KYYPRIEVSE-DCDECEKCVEACPRGVLELKEGKLVVTDLLnCSLCKLCERAC 211
ferrodoxin_EFR1 NF038196
EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...
 9-48 9.77e-04

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).


Pssm-ID: 468407 [Multi-domain]  Cd Length: 243  Bit Score: 40.23  E-value: 9.77e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 2485681954   9 DACLVCNACAKACPTEAIEIAPFK-----TCIQCFSCATACPTGA 48
Cdd:NF038196  185 DKCIGCGICAKVCPVNNIEMEDGKpvwghNCTHCLACIHRCPKEA 229
PRK05035 PRK05035
electron transport complex protein RnfC; Provisional
 308-356 9.80e-04

electron transport complex protein RnfC; Provisional


Pssm-ID: 235334 [Multi-domain]  Cd Length: 695  Bit Score: 41.47  E-value: 9.80e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2485681954 308 CIRCGACAMKCPTGAL--------KmgkmvheGKEYARV-EFSPALCNECGECVDVCP 356
Cdd:PRK05035  372 CIRCGACADACPASLLpqqlywfaK-------AEEHDKAqEYNLFDCIECGACAYVCP 422
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
 152-228 9.86e-04

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 41.31  E-value: 9.86e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 152 IAVIDTDKC--IYC-TVCSQTCPWN-----AIfvagKLPQKRQKTIksftVNEEECIGCEKCVEACPGSMIEYngealgV 223
Cdd:COG1245     4 IAVVDRDRCqpKKCnYECIKYCPVNrtgkeAI----EIDEDDGKPV----ISEELCIGCGICVKKCPFDAISI------V 69


                  ....*
gi 2485681954 224 KLPEA 228
Cdd:COG1245    70 NLPEE 74
porD PRK09625
pyruvate flavodoxin oxidoreductase subunit delta; Reviewed
 195-246 1.10e-03

pyruvate flavodoxin oxidoreductase subunit delta; Reviewed


Pssm-ID: 236596 [Multi-domain]  Cd Length: 133  Bit Score: 38.96  E-value: 1.10e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2485681954 195 NEEECIGCEKCVEACPGSMIEY-NGEALGVKLpEACPACGLCVESCPVEVISL 246
Cdd:PRK09625   57 NNEICINCFNCWVYCPDAAILSrDKKLKGVDY-SHCKGCGVCVEVCPTNPKSL 108
DMSOR_beta_like cd16371
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 192-326 1.11e-03

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319893 [Multi-domain]  Cd Length: 140  Bit Score: 39.08  E-value: 1.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 192 FTVNEEECIGCEKCVEAC-------PG----SMIEYNG----EALGVKLPEAC-----PACglcVESCPVEVISleveya 251
Cdd:cd16371     2 FYFDQERCIGCKACEIACkdkndlpPGvnwrRVYEYEGgefpEVFAYFLSMSCnhcenPAC---VKVCPTGAIT------ 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 252 sakpVTDEGLVW-SEEKCAYCGPCAIKCPTGAIKVvnpkgleLPSRNKTEKANefaMCI------RCGACAMKCPTGALK 324
Cdd:cd16371    73 ----KREDGIVVvDQDKCIGCGYCVWACPYGAPQY-------NPETGKMDKCD---MCVdrldegEKPACVAACPTRALD 138


                  ..
gi 2485681954 325 MG 326
Cdd:cd16371   139 FG 140
Fer4_7 pfam12838
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 160-210 1.15e-03

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 463724 [Multi-domain]  Cd Length: 51  Bit Score: 36.74  E-value: 1.15e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2485681954 160 CIYCTVCSQTCPWNAIFVAGKLPQKRQKTIksfTVNEEECIGCEKCVEACP 210
Cdd:pfam12838   1 CIGCGACVAACPVGAITLDEVGEKKGTKTV---VIDPERCVGCGACVAVCP 48
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
152-228 1.19e-03

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 40.95  E-value: 1.19e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 152 IAVIDTDKCI--YC-TVCSQTCPWN-----AIfvagKLPQKRQKTIKSftvnEEECIGCEKCVEACPGSMIEYngealgV 223
Cdd:PRK13409    4 IAVVDYDRCQpkKCnYECIKYCPVVrtgeeTI----EIDEDDGKPVIS----EELCIGCGICVKKCPFDAISI------V 69


                  ....*
gi 2485681954 224 KLPEA 228
Cdd:PRK13409   70 NLPEE 74
PRK08493 PRK08493
NADH-quinone oxidoreductase subunit G;
86-151 1.24e-03

NADH-quinone oxidoreductase subunit G;


Pssm-ID: 236277 [Multi-domain]  Cd Length: 819  Bit Score: 40.84  E-value: 1.24e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954  86 YSKGHCVLCEKCVDICPAEI-----ISLPGKAEKPKKEI--IIPQEPIAV---------------TKDCVACGVCVPECP 143
Cdd:PRK08493  138 YDPSLCIVCERCVTVCKDKIgesalKTVPRGLDAPDKSFkeSMPKDAYAVwskkqksligpvggeTLDCSFCGECIAVCP 217


                  ....*...
gi 2485681954 144 VDAISIED 151
Cdd:PRK08493  218 VGALSSSD 225
PRK00783 PRK00783
DNA-directed RNA polymerase subunit D; Provisional
 223-285 1.27e-03

DNA-directed RNA polymerase subunit D; Provisional


Pssm-ID: 234837 [Multi-domain]  Cd Length: 263  Bit Score: 40.25  E-value: 1.27e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2485681954 223 VKLPEACPACGLCVESCPVEVISLEveyaSAKPVTDEglvwsEEKCAYCGPCAIKCPTGAIKV 285
Cdd:PRK00783  165 IEVSEDCDECEKCVEACPRGVLELK----EGKLVVTD-----LLNCSLCKLCERACPGKAIRV 218
PreA COG1146
NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...
 308-367 1.27e-03

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];


Pssm-ID: 440761 [Multi-domain]  Cd Length: 67  Bit Score: 37.00  E-value: 1.27e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 308 CIRCGACAMKCPTGALKMGKmvhegKEYARVEFSPALCNECGECVDVCPQKTLELTGDDK 367
Cdd:COG1146    10 CIGCGACVEVCPVDVLELDE-----EGKKALVINPEECIGCGACELVCPVGAITVEDDEP 64
PRK08222 PRK08222
hydrogenase 4 subunit H; Validated
 306-368 1.28e-03

hydrogenase 4 subunit H; Validated


Pssm-ID: 181301 [Multi-domain]  Cd Length: 181  Bit Score: 39.35  E-value: 1.28e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2485681954 306 AMCIRCGACAMKCPTGALKMGKMVHEGKEYARVEFspALCNECGECVDVCPQKTLELTGDDKM 368
Cdd:PRK08222   38 SQCIACGACTCACPANALTIQTDDQQNSRTWQLYL--GRCIYCGRCEEVCPTRAIQLTNNFEL 98
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 34-76 1.29e-03

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 37.03  E-value: 1.29e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 2485681954  34 CIQCFSCATACPTGALV----EKDGKLVFNGSKCDLDGACAKACPVG 76
Cdd:COG1143     4 CIGCGLCVRVCPVDAITiedgEPGKVYVIDPDKCIGCGLCVEVCPTG 50
TH_beta_N cd10552
N-terminal FeS domain of pyrogallol-phloroglucinol transhydroxylase (TH), beta subunit; This ...
 197-261 1.29e-03

N-terminal FeS domain of pyrogallol-phloroglucinol transhydroxylase (TH), beta subunit; This family includes the beta subunit of pyrogallol-phloroglucinol transhydroxylase (TH), a cytoplasmic molybdenum (Mo) enzyme from anaerobic microorganisms like Pelobacter acidigallici and Desulfitobacterium hafniense which catalyzes the conversion of pyrogallol to phloroglucinol, an important building block of plant polymers. TH belongs to the DMSO reductase (DMSOR) family; it is a heterodimer consisting of a large alpha catalytic subunit and a small beta FeS subunit. The beta subunit has two domains with the N-terminal domain containing three [4Fe-4S] centers and a seven-stranded, mainly antiparallel beta-barrel domain. In the anaerobic bacterium Pelobacter acidigallici, gallic acid, pyrogallol, phloroglucinol, or phloroglucinol carboxylic acid are fermented to three molecules of acetate (plus CO2), and TH is the key enzyme in the fermentation pathway, which converts pyrogallol to phloroglucinol in the absence of O2.


Pssm-ID: 319874 [Multi-domain]  Cd Length: 186  Bit Score: 39.62  E-value: 1.29e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2485681954 197 EECIGCEKCVEACPGSMIEYNGEAlgvKLPEACPACG----------LCVESCPVEVISL--EVEYASAKPVTDEGL 261
Cdd:cd10552    94 EKAKGQKQLVDACPYGAIYWNEEL---QVPQKCTFCAhllddgwkepRCVQACPTGALRFgkLEDEEMAAKAAEEGL 167
NuoI TIGR01971
NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of ...
 227-284 1.32e-03

NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of the NADH-quinone oxidoreductase complex I which generally couples NADH and ubiquinone oxidation/reduction in bacteria and mammalian mitochondria, but may act on NADPH and/or plastoquinone in cyanobacteria and plant chloroplasts. This model excludes "I" subunits from the closely related F420H2 dehydrogenase and formate hydrogenlyase complexes. [Energy metabolism, Electron transport]


Pssm-ID: 273902 [Multi-domain]  Cd Length: 122  Bit Score: 38.55  E-value: 1.32e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2485681954 227 EACPACGLCVESCPVEVISLEVEYASAKPVTDEGLVWSEEKCAYCGPCAIKCPTGAIK 284
Cdd:TIGR01971  43 EKCIGCTLCAAVCPADAIRVVPAEGEDGKRRLKFYEINFGRCIFCGLCEEACPTDAIV 100
PRK00783 PRK00783
DNA-directed RNA polymerase subunit D; Provisional
 88-151 1.34e-03

DNA-directed RNA polymerase subunit D; Provisional


Pssm-ID: 234837 [Multi-domain]  Cd Length: 263  Bit Score: 40.25  E-value: 1.34e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2485681954  88 KGHCVLCEKCVDICPAEIISLPGKAEKPKKEIiipqepiavtkDCVACGVCVPECPVDAISIED 151
Cdd:PRK00783  168 SEDCDECEKCVEACPRGVLELKEGKLVVTDLL-----------NCSLCKLCERACPGKAIRVSD 220
PRK12769 PRK12769
putative oxidoreductase Fe-S binding subunit; Reviewed
 195-325 1.49e-03

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183733 [Multi-domain]  Cd Length: 654  Bit Score: 40.89  E-value: 1.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 195 NEEECIGCEKCVEACpgsMIEYNGE-----------------ALGVKLPEACPAC--GLCVESCPVEVISLeveyasakp 255
Cdd:PRK12769    8 NSQQCLGCHACEIAC---VMAHNDEqhvlsqhhfhpritvikHQQQRSAVTCHHCedAPCARSCPNGAISH--------- 75

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2485681954 256 vTDEGLVWSEEKCAYCGPCAIKCPTGAIKVVNPKGleLPSRNKTEkANEFAMCI---RCGACAMKCPTGALKM 325
Cdd:PRK12769   76 -VDDSIQVNQQKCIGCKSCVVACPFGTMQIVLTPV--AAGKVKAT-AHKCDLCAgreNGPACVENCPADALQL 144
PRK12809 PRK12809
putative oxidoreductase Fe-S binding subunit; Reviewed
 154-302 1.49e-03

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183762 [Multi-domain]  Cd Length: 639  Bit Score: 40.78  E-value: 1.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 154 VIDTDKCIYCTVCSQTCPwnAIFVAGKLPQKRQKTI-------KSFTVNEEECIGCEK--CVEACPGSMIEYNGEAlgVK 224
Cdd:PRK12809    6 AAEAAECIGCHACEIACA--VAHNQENWPLSHSDFRprihvvgKGQAANPVACHHCNNapCVTACPVNALTFQSDS--VQ 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 225 LPEA-CPACGLCVESCPVEVISLEVEYAsakpvtdeglvwseEKCAYCG-------PCAIKCPTGAIKVVNPKGLELPSR 296
Cdd:PRK12809   82 LDEQkCIGCKRCAIACPFGVVEMVDTIA--------------QKCDLCNqrssgtqACIEVCPTQALRLMDDKGLQQIKV 147


                  ....*.
gi 2485681954 297 NKTEKA 302
Cdd:PRK12809  148 ARQRKT 153
PorD COG1144
Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...
 226-286 1.53e-03

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit [Energy production and conversion]; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit is part of the Pathway/BioSystem: Pyruvate oxidation


Pssm-ID: 440759 [Multi-domain]  Cd Length: 84  Bit Score: 37.34  E-value: 1.53e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2485681954 226 PEACPACGLCVESCPVEVISleveyasakPVTDEGLVWSEEKCAYCGPCAIKCPTGAIKVV 286
Cdd:COG1144    29 EDKCIGCGLCWIVCPDGAIR---------VDDGKYYGIDYDYCKGCGICAEVCPVKAIEMV 80
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 335-384 1.56e-03

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 36.95  E-value: 1.56e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 2485681954 335 YARVEFSPALCNECGECVDVCPQKTLELTGDDKMPLKGYCVMCLKCIEAC 384
Cdd:COG2221     7 TWPPKIDEEKCIGCGLCVAVCPTGAISLDDGKLVIDEEKCIGCGACIRVC 56
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
52-114 1.64e-03

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 37.02  E-value: 1.64e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2485681954  52 KDGKLVFNGSKCDLDGACAKACPVG-IKKVDDRFPYSKGHCVLCEKCVDICPAEIISLPGKAEK 114
Cdd:COG2768     2 SLGKPYVDEEKCIGCGACVKVCPVGaISIEDGKAVIDPEKCIGCGACIEVCPVGAIKIEWEEDE 65
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 3-50 1.66e-03

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 38.15  E-value: 1.66e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2485681954   3 GISIQEDACLVCNACAKACPTEAIEIAPFKT-------CIQCFSCATACPTGALV 50
Cdd:cd10549    72 EAEIDEEKCIGCGLCVKVCPVDAITLEDELEividkekCIGCGICAEVCPVNAIK 126
DMSOR_beta-like cd04410
Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta ...
 261-377 1.67e-03

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319870 [Multi-domain]  Cd Length: 136  Bit Score: 38.52  E-value: 1.67e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 261 LVWSEEKCAYCGPCAIKCPTGAIKVVNPKGLELPSRNKTEKANEFA--MCIRCG--ACAMKCPTGALKMGKMvhegkeyA 336
Cdd:cd04410     1 LVVDLDRCIGCGTCEVACKQEHGLRPGPDWSRIKVIEGGGLERAFLpvSCMHCEdpPCVKACPTGAIYKDED-------G 73

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 2485681954 337 RVEFSPALCNECGECVDVCPQKTLELTGDDKMPLKgyCVMC 377
Cdd:cd04410    74 IVLIDEDKCIGCGSCVEACPYGAIVFDPEPGKAVK--CDLC 112
rnfC TIGR01945
electron transport complex, RnfABCDGE type, C subunit; The six subunit complex RnfABCDGE in ...
 193-250 1.73e-03

electron transport complex, RnfABCDGE type, C subunit; The six subunit complex RnfABCDGE in Rhodobacter capsulatus encodes an apparent NADH oxidoreductase responsible for electron transport to nitrogenase, necessary for nitrogen fixation. A closely related complex in E. coli, RsxABCDGE (Reducer of SoxR), reduces the 2Fe-2S-containing superoxide sensor SoxR, active as a transcription factor when oxidized. This family of putative NADH oxidoreductase complexes exists in many of the same species as the related NQR, a Na(+)-translocating NADH-quinone reductase, but is distinct. This model describes the C subunit. [Energy metabolism, Electron transport]


Pssm-ID: 273888 [Multi-domain]  Cd Length: 435  Bit Score: 40.40  E-value: 1.73e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2485681954 193 TVNEEECIGCEKCVEACPGSMI--EYNGEALGVKLPEA-------CPACGLCVESCPVEvISLeVEY 250
Cdd:TIGR01945 359 ESPEKPCIRCGKCVQVCPMNLLpqQLNWLALADEFDEAeehnlmdCIECGCCSYVCPSN-IPL-VQY 423
PRK13984 PRK13984
putative oxidoreductase; Provisional
 172-357 1.76e-03

putative oxidoreductase; Provisional


Pssm-ID: 172486 [Multi-domain]  Cd Length: 604  Bit Score: 40.52  E-value: 1.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 172 WNAIF---VAGKLPQKRQKT---IKSFTVNE-EECIGCEKCVEACPGSMIEYngealgvklpeacpacglcvescpVEVI 244
Cdd:PRK13984   13 WKFLFrkpVTIKVPNVKREAaerYRGFHINDwEKCIGCGTCSKICPTDAITM------------------------VEVP 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 245 SLEVEYASA--KPVTDEGlvwseeKCAYCGPCAIKCPTGAIKV----------------------VNPKGL-ELPSRNKT 299
Cdd:PRK13984   69 DLPQEYGKKpqRPVIDYG------RCSFCALCVDICTTGSLKMtreyihispdpedfifmptekgINAKEPdNAPLGWVR 142

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 300 EKANEFAMCIRcgaCAMKCPTGALKMGKMVHEGKEYARVE--FSPALCNECGECVDVCPQ 357
Cdd:PRK13984  143 DENSELLDLER---VEMEEIPPEERVKSFIEIVKGYSKEQamQEAARCVECGICTDTCPA 199
ferrodoxin_EFR1 NF038196
EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...
 227-283 1.76e-03

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).


Pssm-ID: 468407 [Multi-domain]  Cd Length: 243  Bit Score: 39.46  E-value: 1.76e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2485681954 227 EACPACGLCVESCPVEVISLEVEyasaKPvtdeglVWSeEKCAYCGPCAIKCPTGAI 283
Cdd:NF038196  185 DKCIGCGICAKVCPVNNIEMEDG----KP------VWG-HNCTHCLACIHRCPKEAI 230
NapH COG0348
Polyferredoxin NapH [Energy production and conversion];
265-326 1.82e-03

Polyferredoxin NapH [Energy production and conversion];


Pssm-ID: 440117 [Multi-domain]  Cd Length: 263  Bit Score: 39.66  E-value: 1.82e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2485681954 265 EEKCAYCGPCAIKCPTGaikvvnpkgleLPSRNKTEKANEfamCIRCGACAMKCPTGALKMG 326
Cdd:COG0348   209 RGDCIDCGLCVKVCPMG-----------IDIRKGEINQSE---CINCGRCIDACPKDAIRFS 256
PreA COG1146
NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...
 4-49 1.90e-03

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];


Pssm-ID: 440761 [Multi-domain]  Cd Length: 67  Bit Score: 36.61  E-value: 1.90e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2485681954   4 ISIQEDACLVCNACAKACPTEAIEIAPFKT---------CIQCFSCATACPTGAL 49
Cdd:COG1146     3 PVIDTDKCIGCGACVEVCPVDVLELDEEGKkalvinpeeCIGCGACELVCPVGAI 57
RNAP_D cd07030
D subunit of Archaeal RNA polymerase; The D subunit of archaeal RNA polymerase (RNAP) is ...
 333-386 2.04e-03

D subunit of Archaeal RNA polymerase; The D subunit of archaeal RNA polymerase (RNAP) is involved in the assembly of RNAP subunits. RNAP is a large multi-subunit complex responsible for the synthesis of RNA. It is the principal enzyme of the transcription process, and is a final target in many regulatory pathways that control gene expression in all living cells. A single distinct RNAP complex is found in archaea, which may be responsible for the synthesis of all RNAs. The archaeal RNAP harbors homologues of all eukaryotic RNAP II subunits with two exceptions (RPB8 and RPB9). The 12 archaeal subunits are designated by letters and can be divided into three functional groups that are engaged in: (I) catalysis (A'/A", B'/B" or B); (II) assembly (L, N, D and P); and (III) auxiliary functions (F, E, H and K). The D subunit is equivalent to the RPB3 subunit of eukaryotic RNAP II. It contains two subdomains: one subdomain is similar the eukaryotic Rpb11/AC19/archaeal L subunit which is involved in dimerization, and the other is an inserted beta sheet subdomain. The assembly of the two largest archaeal RNAP subunits that provide most of the enzyme's catalytic functions depends on the presence of the archaeal D/L heterodimer.


Pssm-ID: 132908 [Multi-domain]  Cd Length: 259  Bit Score: 39.56  E-value: 2.04e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2485681954 333 KEYARVEFSPAlCNECGECVDVCPQKTLELTGD-DKMPLKGYCVMCLKCIEACNK 386
Cdd:cd07030   160 KYYPVIEIDED-CDGCGKCVEECPRGVLELEEGkVVVEDLEDCSLCKLCERACDA 213
PRK06273 PRK06273
ferredoxin; Provisional
 91-176 2.07e-03

ferredoxin; Provisional


Pssm-ID: 235764 [Multi-domain]  Cd Length: 165  Bit Score: 38.54  E-value: 2.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954  91 CVLCEKCVDICPAEIIslpgkaekpkkeIIIPQEPIAVTKDCVAcgvcvpecpvdaisiEDIAVIDTDKCIYCTVCSQTC 170
Cdd:PRK06273   51 CIGCGGCANVCPTKAI------------EMIPVEPVKITEGYVK---------------TKIPKIDYEKCVYCLYCHDFC 103


                  ....*.
gi 2485681954 171 PWNAIF 176
Cdd:PRK06273  104 PVFALF 109
PRK08348 PRK08348
NADH-plastoquinone oxidoreductase subunit; Provisional
 195-250 2.11e-03

NADH-plastoquinone oxidoreductase subunit; Provisional


Pssm-ID: 181399 [Multi-domain]  Cd Length: 120  Bit Score: 37.89  E-value: 2.11e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2485681954 195 NEEECIGCEKCVEACPGSMIEYNGEALGVKLPEA-CPACGLCVESCPVEVISLEVEY 250
Cdd:PRK08348   40 DVDKCVGCRMCVTVCPAGVFVYLPEIRKVALWTGrCVFCGQCVDVCPTGALQMSDDF 96
DMSOR_beta_like cd10550
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 199-286 2.28e-03

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319872 [Multi-domain]  Cd Length: 130  Bit Score: 37.94  E-value: 2.28e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 199 CIGCEK--CVEACPGSMIEYNgEALGVKL--PEACPACGLCVESCPVEVISLEVEYASAkpvtdeglvwseEKCAYCGP- 273
Cdd:cd10550    49 CRQCEDapCVEACPVGAISRD-EETGAVVvdEDKCIGCGMCVEACPFGAIRVDPETGKA------------IKCDLCGGd 115

                          90
                  ....*....|....*
gi 2485681954 274 --CAIKCPTGAIKVV 286
Cdd:cd10550   116 paCVKVCPTGALEFV 130
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
135-184 2.42e-03

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 39.79  E-value: 2.42e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2485681954 135 CG-VCVPECPV-----DAISIEDI---AVIDTDKCIYCTVCSQTCPWNAIFVAGkLPQK 184
Cdd:PRK13409   17 CNyECIKYCPVvrtgeETIEIDEDdgkPVISEELCIGCGICVKKCPFDAISIVN-LPEE 74
PRK10194 PRK10194
ferredoxin-type protein NapF;
34-150 2.42e-03

ferredoxin-type protein NapF;


Pssm-ID: 182296 [Multi-domain]  Cd Length: 163  Bit Score: 38.47  E-value: 2.42e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954  34 CIQCFSCATACPTGALVEKDG---KLVFNGSKCDLDGACAKACPVGI------KKVDDRFPYSKG----HCVLCEKCVDI 100
Cdd:PRK10194   36 CTRCDACINACENNILQRGAGgypSVNFKNNECSFCYACAQACPESLfsprhtRAWDLQFTIGDAclayQSVECRRCQDS 115

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 2485681954 101 CPAEIISLpgkaeKPKKEIIIpqEPIAVTKDCVACGVCVPECPVDAISIE 150
Cdd:PRK10194  116 CEPMAIIF-----RPTLSGIY--QPQLNSQLCNGCGACAASCPVSAITAE 158
PRK12771 PRK12771
putative glutamate synthase (NADPH) small subunit; Provisional
 268-326 2.48e-03

putative glutamate synthase (NADPH) small subunit; Provisional


Pssm-ID: 237198 [Multi-domain]  Cd Length: 564  Bit Score: 39.86  E-value: 2.48e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2485681954 268 CAYCGPCAIKCPTGAIKVVNPKGlelpsrnktEKANEFAMCIRCGACAMKCPTGALKMG 326
Cdd:PRK12771  512 CFECDNCYGACPQDAIIKLGPGR---------RYHFDYDKCTGCHICADVCPCGAIEMG 561
PRK06273 PRK06273
ferredoxin; Provisional
 193-241 2.55e-03

ferredoxin; Provisional


Pssm-ID: 235764 [Multi-domain]  Cd Length: 165  Bit Score: 38.54  E-value: 2.55e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2485681954 193 TVNEEECIGCEKCVEACPGSMIE------------YNGEALGVKLPEACPACGLCVESCPV 241
Cdd:PRK06273   45 KVFEELCIGCGGCANVCPTKAIEmipvepvkitegYVKTKIPKIDYEKCVYCLYCHDFCPV 105
Fer4_7 pfam12838
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 91-146 2.77e-03

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 463724 [Multi-domain]  Cd Length: 51  Bit Score: 35.58  E-value: 2.77e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2485681954  91 CVLCEKCVDICPAEIISLPGKAEKPKKEIIIPQEpiavtKDCVACGVCVPECPVDA 146
Cdd:pfam12838   1 CIGCGACVAACPVGAITLDEVGEKKGTKTVVIDP-----ERCVGCGACVAVCPTGA 51
PRK12387 PRK12387
formate hydrogenlyase complex iron-sulfur subunit; Provisional
 122-175 2.79e-03

formate hydrogenlyase complex iron-sulfur subunit; Provisional


Pssm-ID: 183492 [Multi-domain]  Cd Length: 180  Bit Score: 38.47  E-value: 2.79e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2485681954 122 PQEPIAVTKD-----------CVACGVCVPECPVDAISIE-DIAV------IDTDKCIYCTVCSQTCPWNAI 175
Cdd:PRK12387   19 PLEPIAVDKNfrgkpeynpqqCIGCAACVNACPSNALTVEtDLATgelaweFNLGRCIFCGRCEEVCPTAAI 90
DMSOR_beta_like cd16367
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 137-178 2.91e-03

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319889 [Multi-domain]  Cd Length: 138  Bit Score: 37.67  E-value: 2.91e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 2485681954 137 VCVPECPVDAIS-IEDIAVIDTDKCIYCTVCSQTCPWNAIFVA 178
Cdd:cd16367    64 VCMIGCPTGAIHrDDGGEVVISDACCGCGNCASACPYGAIQMV 106
HycB COG1142
Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];
226-363 2.97e-03

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];


Pssm-ID: 440757 [Multi-domain]  Cd Length: 138  Bit Score: 37.71  E-value: 2.97e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 226 PEACPACGLCVESCPVEVISLEVEYASAK-PVTDEGLVWSEEKCAYC--GPCAIKCPTGAIKVVNPKGLELPSRnkteka 302
Cdd:COG1142     9 PEKCIGCRTCEAACAVAHEGEEGEPFLPRiRVVRKAGVSAPVQCRHCedAPCAEVCPVGAITRDDGAVVVDEEK------ 82

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2485681954 303 nefamCIRCGACAMKCPTGALKMgkmvhEGKEYARVEFSPALCNECGE---CVDVCPQKTLELT 363
Cdd:COG1142    83 -----CIGCGLCVLACPFGAITM-----VGEKSRAVAVKCDLCGGREGgpaCVEACPTGALRLV 136
PRK08348 PRK08348
NADH-plastoquinone oxidoreductase subunit; Provisional
 54-108 3.11e-03

NADH-plastoquinone oxidoreductase subunit; Provisional


Pssm-ID: 181399 [Multi-domain]  Cd Length: 120  Bit Score: 37.12  E-value: 3.11e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2485681954  54 GKLVFNGSKCDLDGACAKACPVG-------IKKVddrfPYSKGHCVLCEKCVDICPAEIISL 108
Cdd:PRK08348   35 GKILYDVDKCVGCRMCVTVCPAGvfvylpeIRKV----ALWTGRCVFCGQCVDVCPTGALQM 92
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
8-49 3.14e-03

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 39.46  E-value: 3.14e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 2485681954   8 EDACLVCNACAKACPTEAIEIAPFKT-------CIQCFSCATACPTGAL 49
Cdd:COG1148   495 PEKCTGCGRCVEVCPYGAISIDEKGVaevnpalCKGCGTCAAACPSGAI 543
vorD PRK09623
3-methyl-2-oxobutanoate dehydrogenase subunit delta;
125-175 3.19e-03

3-methyl-2-oxobutanoate dehydrogenase subunit delta;


Pssm-ID: 170016 [Multi-domain]  Cd Length: 105  Bit Score: 36.85  E-value: 3.19e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2485681954 125 PIAVTKDCVACGVCVPECPVDAISIED--IAVIDTDKCIYCTVCSQTCPWNAI 175
Cdd:PRK09623   46 PVVDESKCVKCYICWKFCPEPAIYIKEdgYVAIDYDYCKGCGICANECPTKAI 98
DMSOR_beta_like cd16372
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 307-384 3.19e-03

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319894 [Multi-domain]  Cd Length: 125  Bit Score: 37.32  E-value: 3.19e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 307 MCIRCGACAMKCPTGALKmgkmvHEGKEYARVE-------FSPALCNECGECVDVCPqkTLELTGDDK---MPLKGYCVM 376
Cdd:cd16372     9 KCIGCLQCEEACSKTFFK-----EEDREKSCIRiteteggYAINVCNQCGECIDVCP--TGAITRDANgvvMINKKLCVG 81


                  ....*...
gi 2485681954 377 CLKCIEAC 384
Cdd:cd16372    82 CLMCVGFC 89
HycB_like cd10554
HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a ...
 273-362 3.23e-03

HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a membrane-associated formate hydrogenlyase system (FHL-1) in Escherichia coli that breaks down formate, produced during anaerobic fermentation, to H2 and CO2. FHL-1 consists of formate dehydrogenase H (FDH-H) and the hydrogenase 3 complex (Hyd-3). HycB is thought to code for the [4Fe-4S] ferredoxin subunit of hydrogenase 3, which functions as an intermediate electron carrier protein between hydrogenase 3 and formate dehydrogenase. HydN codes for the [4Fe-4S] ferredoxin subunit of FDH-H; a hydN in-frame deletion mutation causes only weak reduction in hydrogenase activity, but loss of more than 60% of FDH-H activity. This pathway is only active at low pH and high formate concentrations, and is thought to provide a detoxification/de-acidification system countering the buildup of formate during fermentation.


Pssm-ID: 319876 [Multi-domain]  Cd Length: 149  Bit Score: 37.62  E-value: 3.23e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 273 PCAIKCPTGAIKVVNpkglelpsrnKTEKANEfAMCIRCGACAMKCPTGALKMGKMVHEGKEYARVEFSPA----LCNEC 348
Cdd:cd10554    63 PCANVCPVGAISQED----------GVVQVDE-ERCIGCKLCVLACPFGAIEMAPTTVPGVDWERGPRAVAvkcdLCAGR 131

                          90
                  ....*....|....*..
gi 2485681954 349 GE---CVDVCPQKTLEL 362
Cdd:cd10554   132 EGgpaCVEACPTKALTL 148
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 91-152 3.28e-03

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 35.80  E-value: 3.28e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2485681954  91 CVLCEKCVDICPAEIISLpgkaEKPKKEIIipqepiavTKDCVACGVCVPECPVDAISIEDI 152
Cdd:COG2221    17 CIGCGLCVAVCPTGAISL----DDGKLVID--------EEKCIGCGACIRVCPTGAIKGEKP 66
Fer4_10 pfam13237
4Fe-4S dicluster domain; This family includes proteins containing domains which bind to ...
 194-240 3.49e-03

4Fe-4S dicluster domain; This family includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. The structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 404174 [Multi-domain]  Cd Length: 56  Bit Score: 35.69  E-value: 3.49e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2485681954 194 VNEEECIGCEKCVEACPGSMIEYNGEAL------GVKLPEACPACGLCVESCP 240
Cdd:pfam13237   4 IDPDKCIGCGRCTAACPAGLTRVGAIVErlegeaVRIGVWKCIGCGACVEACP 56
DMSOR_beta_like cd16367
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 8-51 3.53e-03

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319889 [Multi-domain]  Cd Length: 138  Bit Score: 37.67  E-value: 3.53e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 2485681954   8 EDACLVCNACAKACPTEAIEIAPFKTCIQCFS-----CATACPTGALVE 51
Cdd:cd16367    85 SDACCGCGNCASACPYGAIQMVRAVKCDLCAGyagpaCVSACPTGAAIR 133
RnfB COG2878
Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and ...
 189-361 3.57e-03

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase


Pssm-ID: 442125 [Multi-domain]  Cd Length: 254  Bit Score: 38.82  E-value: 3.57e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 189 IKSFTVNEEECIGCEKCVEACPGSMIEYNGEALGVKLPEACPACGLCVEscpvevisleveyasakpvtdeglvwseekc 268
Cdd:COG2878   129 IGGPKGCEYGCIGCGDCIKACPFDAIVGAAKGMHTVDEDKCTGCGLCVE------------------------------- 177

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 269 aycgpcaiKCPTGAIKVVN-PKGLELPSRNKTEKANEFAMCIRCgaCAMKCPTGALKMGKMVHEGKEYARvefspalCNE 347
Cdd:COG2878   178 --------ACPVDCIEMVPvSPTVVVSSWDKGKAVRKVVGCIGL--CCKKCCPAAAITVNNLAAIIDYKK-------CTC 240

                         170
                  ....*....|....
gi 2485681954 348 CGECVDVCPQKTLE 361
Cdd:COG2878   241 CGCCEKCCPTAIIA 254
ACS_1 cd01916
Acetyl-CoA synthase (ACS), also known as acetyl-CoA decarbonylase, is found in acetogenic and ...
 174-259 3.64e-03

Acetyl-CoA synthase (ACS), also known as acetyl-CoA decarbonylase, is found in acetogenic and methanogenic organisms and is responsible for the synthesis and breakdown of acetyl-CoA. ACS forms a heterotetramer with carbon monoxide dehydrogenase (CODH) consisting of two ACS and two CODH subunits. CODH reduces carbon dioxide to carbon monoxide and ACS then synthesizes acetyl-CoA from carbon monoxide, CoA, and a methyl group donated by another protein (CoFeSP). ACS has three structural domains, an N-terminal rossman fold domain with a helical region at its N-terminus which interacts with CODH, and two alpha + beta fold domains. A Ni-Fe-S center referred to as the A-cluster is located in the C-terminal domain. A large cavity exists between the three domains which may bind CoA.


Pssm-ID: 238897 [Multi-domain]  Cd Length: 731  Bit Score: 39.31  E-value: 3.64e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 174 AIFVAGKLPQKRQKTIKSFTVNE-----EECIGCEKCVEACPGSMieYNGEALG----------VKLPEACPACGLCVES 238
Cdd:cd01916   337 AVEVAMAVKPKRKGEKKLPTDEEfqelaAKCTDCGWCTRACPNSL--RIKEAMEaakegdfsglADLFDQCVGCGRCEQE 414

                          90       100
                  ....*....|....*....|...
gi 2485681954 239 CPVE--VISLeVEYASAKPVTDE 259
Cdd:cd01916   415 CPKEipIINM-IEKAARERIKEE 436
PRK08318 PRK08318
NAD-dependent dihydropyrimidine dehydrogenase subunit PreA;
194-242 3.71e-03

NAD-dependent dihydropyrimidine dehydrogenase subunit PreA;


Pssm-ID: 236237 [Multi-domain]  Cd Length: 420  Bit Score: 39.16  E-value: 3.71e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2485681954 194 VNEEECIGCEKCVEAC-PGS----MIEYNGEALGVKLPEACPACGLCVESCPVE 242
Cdd:PRK08318  339 IDQDKCIGCGRCYIACeDTShqaiEWDEDGTRTPEVIEEECVGCNLCAHVCPVE 392
NapF_like cd10564
NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, ...
 343-384 3.74e-03

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, the iron-sulfur subunit of periplasmic nitrate reductase. The periplasmic nitrate reductase NapABC of Escherichia coli likely functions during anaerobic growth in low-nitrate environments; napF operon expression is activated by cyclic AMP receptor protein (Crp). NapF is a subfamily of the beta subunit of DMSO reductase (DMSOR) family. DMSOR family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319886 [Multi-domain]  Cd Length: 139  Bit Score: 37.61  E-value: 3.74e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 2485681954 343 ALCNECGECVDVCPQKTLELtGDDKMP----LKGYCVMCLKCIEAC 384
Cdd:cd10564    13 DLCTRCGDCVEACPEGIIVR-GDGGFPeldfSRGECTFCGACAEAC 57
porD PRK09624
pyruvate ferredoxin oxidoreductase subunit delta; Reviewed
 102-175 3.80e-03

pyruvate ferredoxin oxidoreductase subunit delta; Reviewed


Pssm-ID: 170017 [Multi-domain]  Cd Length: 105  Bit Score: 36.93  E-value: 3.80e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2485681954 102 PAEIISLPGKAEKPKKEIIIPQEPIAVTKDCVACGVCVPECPVDAISI--EDIAVIDTDKCIYCTVCSQTCPWNAI 175
Cdd:PRK09624   23 PGAIAYIPGSSVINKTGSWRVFMPEFNRDKCVRCYLCYIYCPEPAIYLdeEGYPVFDYDYCKGCGICANECPTKAI 98
DMSOR_beta-like cd04410
Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta ...
 91-244 3.92e-03

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319870 [Multi-domain]  Cd Length: 136  Bit Score: 37.37  E-value: 3.92e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954  91 CVLCEKCVDICPAEIiSLPGKAEKPKKEIIIPQEPIAVTKD--CVACG--VCVPECPVDAISIED--IAVIDTDKCIyct 164
Cdd:cd04410     8 CIGCGTCEVACKQEH-GLRPGPDWSRIKVIEGGGLERAFLPvsCMHCEdpPCVKACPTGAIYKDEdgIVLIDEDKCI--- 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 165 vcsqtcpwnaifvagklpqkrqktiksftvneeeciGCEKCVEACPGSMIEYNGEalgVKLPEACPACG---------LC 235
Cdd:cd04410    84 ------------------------------------GCGSCVEACPYGAIVFDPE---PGKAVKCDLCGdrldeglepAC 124


                  ....*....
gi 2485681954 236 VESCPVEVI 244
Cdd:cd04410   125 VKACPTGAL 133
oorD PRK09626
2-oxoglutarate-acceptor oxidoreductase subunit OorD; Reviewed
 129-180 4.03e-03

2-oxoglutarate-acceptor oxidoreductase subunit OorD; Reviewed


Pssm-ID: 236597 [Multi-domain]  Cd Length: 103  Bit Score: 36.62  E-value: 4.03e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2485681954 129 TKDCVACGVCVPECPVDAISIED---------IAVIDTDKCIYCTVCSQTCPWNAIFVAGK 180
Cdd:PRK09626   15 ESRCKACDICVSVCPAGVLAMRIdphavlgkmIKVVHPESCIGCRECELHCPDFAIYVADR 75
SIMIBI_bact_arch cd03110
bacterial and archaeal subfamily of SIMIBI; Uncharacterized bacterial and archaeal subfamily ...
 308-363 4.22e-03

bacterial and archaeal subfamily of SIMIBI; Uncharacterized bacterial and archaeal subfamily of SIMIBI superfamily. Proteins in this superfamily contain an ATP-binding domain and use energy from hydrolysis of ATP to transfer electron or ion. The specific function of this family is unknown.


Pssm-ID: 349764 [Multi-domain]  Cd Length: 246  Bit Score: 38.52  E-value: 4.22e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2485681954 308 CIRCGACAMKCPTGALKMGKmvhegkeyARVEFSPALCNECGECVDVCPQKTLELT 363
Cdd:cd03110    66 CIRCGNCERVCKFGAILEFF--------QKLIVDESLCEGCGACVIICPRGAIYLK 113
PRK06273 PRK06273
ferredoxin; Provisional
 5-66 4.35e-03

ferredoxin; Provisional


Pssm-ID: 235764 [Multi-domain]  Cd Length: 165  Bit Score: 37.77  E-value: 4.35e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954   5 SIQEDACLVCNACAKACPTEAIEIAPFK-------------------TCIQCFSCATACPTGALVEKDGKLVFN--GSKC 63
Cdd:PRK06273   45 KVFEELCIGCGGCANVCPTKAIEMIPVEpvkitegyvktkipkidyeKCVYCLYCHDFCPVFALFNEISPIHPRdvGEDI 124


                  ...
gi 2485681954  64 DLD 66
Cdd:PRK06273  125 EVD 127
FDH-O_like cd10560
beta subunit of formate dehydrogenase O (FDH-O) and similar proteins; This subfamily includes ...
 2-49 4.42e-03

beta subunit of formate dehydrogenase O (FDH-O) and similar proteins; This subfamily includes beta subunit of formate dehydrogenase family O (FDH-O), which is highly homologous to formate dehydrogenase N (FDH-N), a member of the DMSO reductase family. In E. coli three formate dehydrogenases are synthesized that are capable of oxidizing formate; Fdh-H, couples formate disproportionation to hydrogen and CO2, and is part of the cytoplasmically oriented formate hydrogenlyase complex, while FDH-N and FDH-O indicate their respective induction after growth with nitrate and oxygen. Little is known about FDH-O, although it shows formate oxidase activity during aerobic growth and is also synthesized during nitrate respiration, similar to FDH-N.


Pssm-ID: 319882 [Multi-domain]  Cd Length: 225  Bit Score: 38.14  E-value: 4.42e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2485681954   2 AGISIQEDACLVCNACAKACPTEAIEIAPFK----TCIQCF---------SCATACPTGAL 49
Cdd:cd10560   101 GTVYIQPDICNGCGYCVAACPFGVIDRNEETgrahKCTLCYdrlkdglepACAKACPTGSI 161
RnfC COG4656
Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfC subunit [Energy production and ...
 308-356 4.69e-03

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfC subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfC subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase


Pssm-ID: 443694 [Multi-domain]  Cd Length: 451  Bit Score: 38.97  E-value: 4.69e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2485681954 308 CIRCGACAMKCPTGAL--KMGKMVhEGKEYAR-VEFSPALCNECGECVDVCP 356
Cdd:COG4656   366 CIRCGRCVDACPMGLLpqQLYWYA-RAGDFDKaEEYNLMDCIECGCCSYVCP 416
GlpC COG0247
Fe-S cluster-containing oxidoreductase, includes glycolate oxidase subunit GlcF [Energy ...
 285-356 5.02e-03

Fe-S cluster-containing oxidoreductase, includes glycolate oxidase subunit GlcF [Energy production and conversion];


Pssm-ID: 440017 [Multi-domain]  Cd Length: 420  Bit Score: 38.90  E-value: 5.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 285 VVNPKGLELPSRNKTEKANEFAMCIRCGACAMKCPT------------GALKMGKMVHEGKEYARV--EFSPAL--CNEC 348
Cdd:COG0247    57 DGDLHDKNLKTLPWKELLDALDACVGCGFCRAMCPSykatgdekdsprGRINLLREVLEGELPLDLseEVYEVLdlCLTC 136


                  ....*...
gi 2485681954 349 GECVDVCP 356
Cdd:COG0247   137 KACETACP 144
DMSOR_beta_like cd10550
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 307-384 5.15e-03

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319872 [Multi-domain]  Cd Length: 130  Bit Score: 36.79  E-value: 5.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 307 MCIRCG--ACAMKCPTGALkmgkmvHEGKEYARVEFSPALCNECGECVDVCPQKTLELTGDDKMPLKgyCVMCL---KCI 381
Cdd:cd10550    48 VCRQCEdaPCVEACPVGAI------SRDEETGAVVVDEDKCIGCGMCVEACPFGAIRVDPETGKAIK--CDLCGgdpACV 119


                  ...
gi 2485681954 382 EAC 384
Cdd:cd10550   120 KVC 122
SIMIBI_bact_arch cd03110
bacterial and archaeal subfamily of SIMIBI; Uncharacterized bacterial and archaeal subfamily ...
 176-247 5.20e-03

bacterial and archaeal subfamily of SIMIBI; Uncharacterized bacterial and archaeal subfamily of SIMIBI superfamily. Proteins in this superfamily contain an ATP-binding domain and use energy from hydrolysis of ATP to transfer electron or ion. The specific function of this family is unknown.


Pssm-ID: 349764 [Multi-domain]  Cd Length: 246  Bit Score: 38.14  E-value: 5.20e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2485681954 176 FVAGKLPQkrqktiksftVNEEECIGCEKCVEACPGSMIEYNGEALGVkLPEACPACGLCVESCPVEVISLE 247
Cdd:cd03110    53 FVGGKKAF----------IDQEKCIRCGNCERVCKFGAILEFFQKLIV-DESLCEGCGACVIICPRGAIYLK 113
IorA COG4231
TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...
 55-114 5.76e-03

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];


Pssm-ID: 443375 [Multi-domain]  Cd Length: 76  Bit Score: 35.40  E-value: 5.76e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2485681954  55 KLVFNGSKCDLDGACAKACPVGIKKVDDRFPY-SKGHCVLCEKCVDICPAEIISLPGKAEK 114
Cdd:COG4231    16 RYVIDEDKCTGCGACVKVCPADAIEEGDGKAViDPDLCIGCGSCVQVCPVDAIKLEKRVPE 76
PorD COG1144
Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...
 6-50 6.21e-03

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit [Energy production and conversion]; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit is part of the Pathway/BioSystem: Pyruvate oxidation


Pssm-ID: 440759 [Multi-domain]  Cd Length: 84  Bit Score: 35.41  E-value: 6.21e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2485681954   6 IQEDACLVCNACAKACPTEAIEIAPFKT-------CIQCFSCATACPTGALV 50
Cdd:COG1144    27 VDEDKCIGCGLCWIVCPDGAIRVDDGKYygidydyCKGCGICAEVCPVKAIE 78
ferrodoxin_EFR1 NF038196
EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...
 255-328 6.65e-03

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).


Pssm-ID: 468407 [Multi-domain]  Cd Length: 243  Bit Score: 37.92  E-value: 6.65e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2485681954 255 PVTDEGLvWSEEKCAYCGPCAIKCPTGAIKVVNPKglelPSRNKTekanefamCIRCGACAMKCPTGALKMGKM 328
Cdd:NF038196  175 KVKDKKF-HVTDKCIGCGICAKVCPVNNIEMEDGK----PVWGHN--------CTHCLACIHRCPKEAIEYGKK 235
ferrodoxin_EFR1 NF038196
EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...
 345-389 6.95e-03

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).


Pssm-ID: 468407 [Multi-domain]  Cd Length: 243  Bit Score: 37.92  E-value: 6.95e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2485681954 345 CNECGECVDVCPQKTLELTgdDKMPL-KGYCVMCLKCIEAC--------NKTKK 389
Cdd:NF038196  187 CIGCGICAKVCPVNNIEME--DGKPVwGHNCTHCLACIHRCpkeaieygKKTKK 238
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 57-117 7.08e-03

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 35.03  E-value: 7.08e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2485681954  57 VFNGSKCDLDGACAKACPVG-IKKVDDRFPYSKGHCVLCEKCVDICPAEIIslpgKAEKPKK 117
Cdd:COG2221    11 KIDEEKCIGCGLCVAVCPTGaISLDDGKLVIDEEKCIGCGACIRVCPTGAI----KGEKPKK 68
QueG COG1600
Epoxyqueuosine reductase QueG (queuosine biosynthesis) [Translation, ribosomal structure and ...
 308-356 7.41e-03

Epoxyqueuosine reductase QueG (queuosine biosynthesis) [Translation, ribosomal structure and biogenesis]; Epoxyqueuosine reductase QueG (queuosine biosynthesis) is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 441208 [Multi-domain]  Cd Length: 345  Bit Score: 38.26  E-value: 7.41e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2485681954 308 CIRCGACAMKCPTGALKMGKMVH----------EGKEYARVEFSPALCNE---CGECVDVCP 356
Cdd:COG1600   186 CGSCTRCLDACPTGAIVAPYVLDarrcisyltiELKGPIPEELRPKMGNRiygCDDCQDVCP 247
HycB_like cd10554
HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a ...
 194-325 7.52e-03

HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a membrane-associated formate hydrogenlyase system (FHL-1) in Escherichia coli that breaks down formate, produced during anaerobic fermentation, to H2 and CO2. FHL-1 consists of formate dehydrogenase H (FDH-H) and the hydrogenase 3 complex (Hyd-3). HycB is thought to code for the [4Fe-4S] ferredoxin subunit of hydrogenase 3, which functions as an intermediate electron carrier protein between hydrogenase 3 and formate dehydrogenase. HydN codes for the [4Fe-4S] ferredoxin subunit of FDH-H; a hydN in-frame deletion mutation causes only weak reduction in hydrogenase activity, but loss of more than 60% of FDH-H activity. This pathway is only active at low pH and high formate concentrations, and is thought to provide a detoxification/de-acidification system countering the buildup of formate during fermentation.


Pssm-ID: 319876 [Multi-domain]  Cd Length: 149  Bit Score: 36.85  E-value: 7.52e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 194 VNEEECIGCEKCVEACPGSMIEYNGEALG-----------------VKLPEACPAC--GLCVESCPVEVISLEveyasak 254
Cdd:cd10554     4 ADPDKCIGCRTCEVACAAAHSGKGIFEAGtdglpflprlrvvktgeVTAPVQCRQCedAPCANVCPVGAISQE------- 76

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2485681954 255 pvtDEGLVWSEEKCAYCGPCAIKCPTGAIKVV-NPKGLELPSRNKTEKANEFAMCIRCG---ACAMKCPTGALKM 325
Cdd:cd10554    77 ---DGVVQVDEERCIGCKLCVLACPFGAIEMApTTVPGVDWERGPRAVAVKCDLCAGREggpACVEACPTKALTL 148
DMSOR_beta_like cd16372
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 152-286 7.73e-03

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319894 [Multi-domain]  Cd Length: 125  Bit Score: 36.16  E-value: 7.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 152 IAVIDTDKCIYCTVCSQTCPwNAIFvagKLPQKRQKTIKsftVNEEE-------CIGCEKCVEACPGSMIEYNGEALGVK 224
Cdd:cd16372     2 LLVTDPEKCIGCLQCEEACS-KTFF---KEEDREKSCIR---ITETEggyainvCNQCGECIDVCPTGAITRDANGVVMI 74

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2485681954 225 LPEACPACGLCVESCPVEVISLEVEYASAKpvtdeglvwseeKCAYCGPCAIKCPTGAIKVV 286
Cdd:cd16372    75 NKKLCVGCLMCVGFCPEGAMFKHEDYPEPF------------KCIACGICVKACPTGALELV 124
PRK08222 PRK08222
hydrogenase 4 subunit H; Validated
 132-175 8.46e-03

hydrogenase 4 subunit H; Validated


Pssm-ID: 181301 [Multi-domain]  Cd Length: 181  Bit Score: 37.04  E-value: 8.46e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2485681954 132 CVACGVCVPECPVDAISIEDIAVIDT-------DKCIYCTVCSQTCPWNAI 175
Cdd:PRK08222   40 CIACGACTCACPANALTIQTDDQQNSrtwqlylGRCIYCGRCEEVCPTRAI 90
PRK13795 PRK13795
hypothetical protein; Provisional
 34-75 8.57e-03

hypothetical protein; Provisional


Pssm-ID: 237510 [Multi-domain]  Cd Length: 636  Bit Score: 38.44  E-value: 8.57e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 2485681954  34 CIQCFSCATACPTGA--LVEKDGKLVFNGSKCDLDGACAKACPV 75
Cdd:PRK13795  583 CVGCGVCVGACPTGAirIEEGKRKISVDEEKCIHCGKCTEVCPV 626
PRK08764 PRK08764
Rnf electron transport complex subunit RnfB;
152-215 9.00e-03

Rnf electron transport complex subunit RnfB;


Pssm-ID: 181550 [Multi-domain]  Cd Length: 135  Bit Score: 36.44  E-value: 9.00e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2485681954 152 IAVIDTDKCIYCTVCSQTCPWNAIFVAGKlpqkrqktiKSFTVNEEECIGCEKCVEACPGSMIE 215
Cdd:PRK08764   79 VAWIVEADCIGCTKCIQACPVDAIVGGAK---------HMHTVIAPLCTGCELCVPACPVDCIE 133
napH PRK09477
quinol dehydrogenase membrane component; Provisional
 312-386 9.44e-03

quinol dehydrogenase membrane component; Provisional


Pssm-ID: 236535 [Multi-domain]  Cd Length: 271  Bit Score: 37.57  E-value: 9.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 312 GACAMKCPTGALK--MGKmvhegKEYARVEFSPA-LCNECGECVDVCPQK---TLELTGDDKMP--LKGYCVMCLKCIEA 383
Cdd:PRK09477  179 GWCGHLCPLGAFYglIGK-----KSLIRVKAHDRqKCTRCMDCFHVCPEPqvlRPPLKGKQSPSqvTSGDCITCGRCIDV 253


                  ...
gi 2485681954 384 CNK 386
Cdd:PRK09477  254 CSE 256
PRK12387 PRK12387
formate hydrogenlyase complex iron-sulfur subunit; Provisional
 305-365 9.53e-03

formate hydrogenlyase complex iron-sulfur subunit; Provisional


Pssm-ID: 183492 [Multi-domain]  Cd Length: 180  Bit Score: 36.93  E-value: 9.53e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2485681954 305 FAMCIRCGACAMKCPTGALKMgkMVHEGKEYARVEFSPALCNECGECVDVCPQKTLELTGD 365
Cdd:PRK12387   37 PQQCIGCAACVNACPSNALTV--ETDLATGELAWEFNLGRCIFCGRCEEVCPTAAIKLSQE 95
vorD PRK09623
3-methyl-2-oxobutanoate dehydrogenase subunit delta;
194-249 9.55e-03

3-methyl-2-oxobutanoate dehydrogenase subunit delta;


Pssm-ID: 170016 [Multi-domain]  Cd Length: 105  Bit Score: 35.69  E-value: 9.55e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2485681954 194 VNEEECIGCEKCVEACPGSMIEYNGEALGVKLPEACPACGLCVESCPVEVISLEVE 249
Cdd:PRK09623   48 VDESKCVKCYICWKFCPEPAIYIKEDGYVAIDYDYCKGCGICANECPTKAITMVKE 103
PRK10194 PRK10194
ferredoxin-type protein NapF;
160-287 9.79e-03

ferredoxin-type protein NapF;


Pssm-ID: 182296 [Multi-domain]  Cd Length: 163  Bit Score: 36.54  E-value: 9.79e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485681954 160 CIYCTVCSQTCPWNAIfvagklpQKRQKTIKSFTVNEEECIGCEKCVEACPGSMI---EYNGEALGVKLPEACPA----- 231
Cdd:PRK10194   36 CTRCDACINACENNIL-------QRGAGGYPSVNFKNNECSFCYACAQACPESLFsprHTRAWDLQFTIGDACLAyqsve 108

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2485681954 232 CGLCVESC-PVEVISLEVEYASAKPVTDEglvwseEKCAYCGPCAIKCPTGAIKVVN 287
Cdd:PRK10194  109 CRRCQDSCePMAIIFRPTLSGIYQPQLNS------QLCNGCGACAASCPVSAITAEY 159
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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