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Metagenome-assembled genome: ERR866566_bin.47_CONCOCT_v1.1_MAG

Identifiers
BioSample: SAMEA14085130; SRA: ERS11688262
Organism
uncultured Veillonellaceae bacterium
cellular organisms; Bacteria; Terrabacteria group; Bacillota; Negativicutes; Veillonellales; Veillonellaceae; environmental samples
Attributes
collection date2011-01-01
broad-scale environmental contextHost-associated
local-scale environmental contextHuman
environmental mediumDigestive system
geographic locationBangladesh
investigation typemetagenome-assembled genome
isolation sourcehuman gut metagenome
project nameDisability after childhood diarrhea is an important burden on global productivity. Recent studies suggest that gut bacterial communities influence how humans recover from infectious diarrhea, but we still lack extensive data and mechanistic hypotheses for how these communities respond to diarrheal disease and its treatment. Here, we report that after V. cholerae infection, human gut microbiota undergo an orderly and reproducible succession featuring transient reversals in relative levels of enteric Bacteroides and Prevotella. Elements of this succession may be a common feature in microbiota recovery from acute secretory diarrhea, as we observed similar successional dynamics after enterotoxigenic Escherichia coli (ETEC) infection. Our metagenomic analyses suggest multiple mechanisms driving microbial succession after cholera, including bacterial dispersal properties, changing enteric oxygen and carbohydrate levels, and phage dynamics. Thus, gut microbiota recovery after cholera may be predictable at the level of community structure, but driven by a complex set of temporally varying ecological processes. Our findings suggest opportunities for diagnostics and therapies targeting the gut microbiota in humans recovering from infectious diarrhea.
sample nameERR866566_bin.47_CONCOCT_v1.1_MAG
ENA-CHECKLISTERC000047
ENA-FIRST-PUBLIC2023-01-03
ENA-LAST-UPDATE2023-01-03
External IdSAMEA14085130
INSDC center aliasEBI
INSDC center nameEuropean Bioinformatics Institute
INSDC first public2023-01-03T00:33:18Z
INSDC last update2023-01-03T00:33:18Z
INSDC statuspublic
Submitter IdERR866566_bin.47_CONCOCT_v1.1_MAG
assembly qualityMany fragments with little to no review of assembly other than reporting of standard assembly statistics
assembly softwarespadesv3.11.1
binning parametersDefault
binning softwareCONCOCT v1.1
broker nameEMG broker account, EMBL-EBI
completeness score90.64
completeness softwareCheckM
contamination score3.1
geographic location (latitude)23.7
geographic location (longitude)90.3667
metagenomic sourcehuman gut metagenome
sample derived fromSAMEA3360662
scientific_nameuncultured Veillonellaceae bacterium
sequencing methodIllumina HiSeq 2000
taxonomic identity markermulti-marker approach
Description

This sample represents a Third Party Annotation (TPA) Metagenome-Assembled Genome (MAG) assembled from the metagenomic run ERR866566 of study ERP010229.

BioProject
PRJEB51075 Large-scale analysis of novel cellular microbes from the human gut biome
Retrieve all samples from this project

Submission
EBI; 2023-01-04
Accession:
SAMEA14085130
ID:
32561757

BioProject Nucleotide

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