Conserved Protein Domain Family
PGBA_C

?
pfam15437: PGBA_C 
Plasminogen-binding protein pgbA C-terminal
PGBA_C is an C-terminal family of bacterial proteins that bind plasminogen. This activity was identified in Helicobacter pylori where it is thought to contribute to the virulence of this bacterium. Both PgbA and PgbB are surface-exposed proteins that mediate binding to plasminogen such that it can be converted into plasmin in the presence of a plasminogen activator.
Statistics
?
PSSM-Id: 292077
Aligned: 2 rows
Threshold Bit Score: 58.566
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
O25534 459 NNATQQGetknnESKNAPvlKENAAKKEVPKPNSKEEKRRLKEEKKKAKAEQRAREFEQRAREHQERDEKELEERRKALE 538 Helicobacter pylori 2...
O25249 376 NNATQQG-----EKQNAP--KENNAQKEENKPNSKEEKRRLKEEKKKAKAEQRAREFEQRAREHQERDEKELEERRKALE 448 Helicobacter pylori 2...
O25534 539 MNKK 542 Helicobacter pylori 26695
O25249 449 AGKK 452 Helicobacter pylori 26695
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap