Conserved Protein Domain Family
LipA

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COG0320: LipA 
Lipoate synthase [Coenzyme transport and metabolism]
Lipoate synthase is part of the Pathway/BioSystem: Lipoate biosynthesis
Statistics
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PSSM-Id: 440089
Aligned: 516 rows
Threshold Bit Score: 375.209
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_020446725   1 M-------SRSRKPEWLRSRIpTGEEFTRVKATLREHDLTTVCEEANCPNLGECWSgaegggpaaasgnaaapgvegnrG 73 
AOR38887       1 M--------QRRLPDYLKRPIiDTDKTRTVRKILKTKCLNTVCENARCPNKNECYT-----------------------K 49 
WP_012544345   1 Md-----yEQIRKPAWIKTNLkDSETAKGVRQALEGLSLNTICVEGRCPNIGTCFN-----------------------H 52 
YP_002249772   1 Mp----------LPEWVKTQLk---EIKKTQNFFKKHKLNTVCETLRCPNRTICYK-----------------------Q 44 
WP_012963223   1 M-------------DWLKVKApQNQVIERTLRVIKKYSLNTVCEESLCPNISECFS-----------------------E 44 
WP_009596228   1 MpkfydkvDVLKKPGWLKIRLhRTPEYAEVQQIVRKHALHTICSSGMCPNKAECWS-----------------------R 57 
WP_014802546   1 Ms------ATAEAPKKTTKRIp--wSFDNETQLLQYQNVHTVCEESRCPNRHECSS-----------------------L 49 
WP_025392284   1 M-----------VPYWLKKNL-NMENIGYMQEILRNLHLHTVCEEAFCPNISECFA-----------------------L 45 
WP_038656090   1 MshddpqqVAGRKPKWLKIKLhNSQGYAEVASLVKQHDLHTICSSGRCPNISECWS-----------------------R 57 
WP_085754695   1 Mknt--ntYKKRFPSWLKTKIsASGNYCRTERIIDSLGINTICVEANCPNKGECWS-----------------------R 55 
WP_020446725  74 GTATFMLLGDQCTRNCGFCDVDTGGGQP---LDPDEPENVASAVAEIGLEYVVLTSVDRDDLEGQGAAHFAETIRELKRR 150
AOR38887      50 NTATFLIMGNDCTRNCKYCNISCARPEP---LDLEEPKHVAEAVQALGLKYAVITSVTRDDLPDGGAEHFANCIYEIRKL 126
WP_012544345  53 GTATFLIMGSICTRHCLYCNVQSGKPMP---VDETEPQRVAEAVKRLRLKYVVLTSVTRDDLEDGGSAFFRQVVEEVKKV 129
YP_002249772  45 PTATFMIMGEVCTRGCKFCNAEKGYPEP---LDNSEPEKIAIAVKEMSLKYVVITSPTRDDLIDGGAKHFAKTVETIKKL 121
WP_012963223  45 GTATFMLMGKVCTRACKYCHVATGRPQK---PDASEPHRLYLAVKELALKHTVLTSVDRDDLKDYGSGHFKRCVEYIKFR 121
WP_009596228  58 RTATFMILGDICTRGCRFCATRTGHPLA---PDAEEPRRVAESVSLMKLRYVVVTSVTRDDLPDGGAAHWAETVRAIRKQ 134
WP_014802546  50 GIATFLIGGRECTRACKFCHIATAKPVPlatIAEKEHDDILRAAIAGKYDYLVITSVARDDDEAGLAAHFARITRSLRAE 129
WP_025392284  46 KTATFLIMGRYCTRNCRFCNVVHHKPEP---INFKEPDMIVQAVKYLNLKYVVITSVTRDDLPDFGSSCFVKVVEKLKPL 122
WP_038656090  58 GTATFMICGDVCTRSCRFCATKSGKPMP---LDRDEPQKIARSIKVMGLRYAVITSVDRDDLPDGGAGQWVDTIEAIKEL 134
WP_085754695  56 GTASVLILGNICTRNCKFCSVPSGSPAH---PDPQEPKKLSKLTSELEIIYLVITSVTRDDLPCGGAAHYRDTVLEIRKN 132
WP_020446725 151 DPGVLVEVLIPDFQG-DPDLVGEIVDAGPDVIAHNVETVERLQERVRdPRAGYEQSLSVLEQVASES-GAHAKTSIMLGH 228
AOR38887     127 CPDTKIEILTPDFKG-NKDCLDVIIKAHPDVFNHNIEAVQDIFKSVR-PQGDYECSLEVLKYVKDNS-DILTKSGLIIGL 203
WP_012544345 130 NPNTKVEALVPDFKK-NEEHWKAFITPQLDVFAHNVEVVRPLFPKLR-PAGDLDVSLSMLKYFKSk--GFLTKTGFMVGV 205
YP_002249772 122 NPDILVEVLVPDFQG-NKTSIETILNSGVAVFAHNIETVKKFYGSVR--KAVYIRSLNILKTAKEINsEIITKSGFMLGL 198
WP_012963223 122 MPEVTIEVLVPDFRG-DVSAMKKLISSSPDIIAHNIETVERLFKQVR-PQGDYRRSLNALKYYADNS-NRPVKSGIMVGL 198
WP_009596228 135 NPDAAIELLIPDLDA-RPDLLDTVIASKPDIIGHNIETVERLTPVVR-SRAKYRTSLETLRHMSRQ--GVATKSGLMVGL 210
WP_014802546 130 --GITVELLIPDFHN-RAEHLAVIAEAGPAVIAHNLETVERLSPSIR-PQAAYERSLQLFKDLKAAWpKIIRKSAFMVGL 205
WP_025392284 123 --NVKIELLIPDFQV-KTECLQAVANSGAQIIGHNIETVKRLYPQAR-PQADYNRSLNVLKSLKRLKpDLITKSGIMVGL 198
WP_038656090 135 NHDVKVEVLIPDFDG-RKELLDLIINSRADVIGHNLETVEELTDSVR-SRAKYTTSLEVLRYISSC--GKEAKSGIMVGL 210
WP_085754695 133 NPNTSFELLTPDFVGcSDKALDFLAEALPFVYSHNIETVEELFPKAR-PQGSYKRSLELLNKFSEKFpEVPLKSSLMLGL 211
WP_020446725 229 GEHDHEVYQALSDCREAGVDVITLGQYLRPSRDHLPVREYVHPHVFDTWRDVAeQELGFLYCASGPMVRSSYRAGELFVE 308
AOR38887     204 GETFEQIEQTLIDLKNVGCDIVTIGQYIQPSKHHLEVAKYYTPEEYDKLRELA-NKVGIKNHQIGPLVRSSYRAAELV-- 280
WP_012544345 206 GESMEDIVNMLEELLNTGVDIVTIGQYLQPSKKHWPVHKYYTPEEFKQLSEIG-QSLGIPAVVSGPMVRSSYLADQYFSQ 284
YP_002249772 199 GENIEEVYNILKDLKNVECDIVTIGQYLQPSKKALPVVEYIKPAVFEKIAEKA-VQIGFKAVVSGPLIRSSTKAYESYLA 277
WP_012963223 199 GESLDEILKTFEDLRRAGVSRLVIGQYLSPSPRHYQVRKYYRPEEFERLRELA-LSFGFERVLSLPLARSSYHAQNLV-- 275
WP_009596228 211 GESDDEVLQTLHDLREAGVGIVTLGQYLRPTLEHYPVAAYITPEKFEWYRLKA-LEMGFAYCASAPLVRSSYLAEEALKS 289
WP_014802546 206 GESDGEVQQLLNDMKSASIDIVSIGQYLRPSAEQAEVVKIYTASEFEELEQSV-VARDFLAHEVGPFVRSSYMAKDTLAK 284
WP_025392284 199 GETQNEVIDTMNDIAQTGCDILTIGQYLQPSKDHLPVTKFLDPSEFEHYKSIA-KKIGFKYVESSVFTRSSYHAENAYNS 277
WP_038656090 211 GETPEQVVKTLEDLRSAGVGRATIGQYLQPTSKQLPVVEYVTPEQFAFYKQKA-VELGFTHIESAPLVRSSYMAEYSEGR 289
WP_085754695 212 GETYLQVEKLLRDLRSCGVQRVAMGQYLKPSKSSLEVQEFITPEKFSYLRNLS-LDMGFEAVQASPFTRSSYMAESM--- 287
WP_020446725 309 ALQRED 314
AOR38887         ------    
WP_012544345 285 LSEPHn 290
YP_002249772 278 VKEERY 283
WP_012963223     ------    
WP_009596228 290 VKSLQR 295
WP_014802546 285 LNAELA 290
WP_025392284 278 LVPRKt 283
WP_038656090 290 AKCV-- 293
WP_085754695     ------    
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