Conserved Protein Domain Family
PRK12893

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PRK12893: PRK12893 
Zn-dependent hydrolase
Links
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Statistics
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PSSM-Id: 237250
Aligned: 74 rows
Threshold Bit Score: 474.754
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
73541064    2 TQNSHPLGQSIIDRAEALARFS--DMEGGLTCAFLTPAHRSAQALLAQWMEQAGMQVRIDAIGNVIGRYEADAaagPDAR 79 
222102817   5 QSVPSIDRTKLQADFDALAALT--EPGRPWTRRSFTPLFLEGRAYLKTRFEEEGLSVRLDAAGNLIGRWEGAQ---RHAP 79 
241207313   2 SRNLPVNASRIAEDIDALAGIT--EPGHPWTRRAFSPLFLEGRAYIDARMKAAGLETRVDAAGNLIGRRTGRK---PWLG 76 
209551930   2 SRNLPVNAGRIAGDIEALAAIT--EPGHPWTRRAFSPLFLEGRAYIEARMKAAELETRIDATGNLIGRRTGRK---PWLG 76 
116250136   2 SRNLPVNASRIAEDIEALAGIT--EPGHPWTRRAFSPLFLDGRAYIEGRMKAAGLETRIDAAGNLIGRRTGRK---PWLG 76 
52081740    6 HKTGESTARNIEDMINWLASFGe-SGEGGVTRLLYSKPWLSAQQSLKEKMEDWGIEPYFDDAGNLFGRIEGTE---NRTK 81 
52787127    6 HKTGESTARNIEDMINWLASFGe-SGEGGVTRLLYSKPWLSAQQSLKEKMEDWGIEPYFDDAGNLFGRIEGTE---NRTK 81 
56965498    1 -MINSLETEQASAYIHYLARFGk-TSDGGNTRLLYTPTWLEAQQAVFSLFQAKGLDAFFDDVGNAYGRIEGTL---ASQA 75 
28210637    1 MISTIEDMQYLEDIFNKFYTIGs-NNQGGVTRLGYSEEEDKMHNIFKLIGEEEGFQTYEDEVGNTYVLNNQES-----NE 74 
23100741    1 ------MEDWLDKKLCELNVTDsmNKPEGFSRLGYTDEEKVAHQRFITIAKELGLSTYQDQAGNQWAKWVVDE----HAP 70 
73541064   80 VLMTGSHFDTVRNGGRYDGRLGILLPIAVVGALHTAGIRLPYHLDIVGFAEEEGLRFKTSFLASSVLAGRFD-AALLTRT 158
222102817  80 VLMTGSHSDTVPSGGRFDGVAGVLSGLAAIRALRLAGYRPQHPIELVDFLAEEPSDWGLSCIGSRGMAGALT-DHHLALL 158
241207313  77 TIMVGSHSDTVPDGGRFDGIAGVISALEVARALVDQNIELDHDLEIVDFLAEEVSIFGVSCIGSRGMTGQLP--EVWLSR 154
209551930  77 TIMVGSHSETVPDGGRFDGIAGVISALEVARALSDQAIELDHDLEIVDFLAEEVSIFGVSCIGSRGMTGQLP--EAWLSR 154
116250136  77 TIMIGSHSDTVPDGGRFDGIAGVISALEVARALVDQNIELDHDLEIVDFLAEEVSIFGVSCIGSRGMTGQLP--EAWLSR 154
52081740   82 AILTGSHIDTVINGGKFDGAYGILASLLSAKHLLDTYGRPKTSIEVVSLCEEEGSRFPLTFWGSGNLTGLFDcQKTPAVH 161
52787127   82 AILTGSHIDTVINGGKFDGAYGILASLLSAKHLLDTYGRPKTSIEVVSLCEEEGSRFPLTFWGSGNLTGLFDcQKTPAVH 161
56965498   76 SIVTGSHIDTVSSGGKFDGAYGIIGSLLAVSRLVSRYGRPKKTIDVVSLCEEEGSRFPLAFWGSGSITGRYEqADIDGLL 155
28210637   75 HYLIGSHLDSVINGGRYDGVAGVIAGLMILKWAKKDKLNI--PIKVVAFRCEESSNFGMCTIGSGLITNEISkNDIENLV 152
23100741   71 TIGLGSHLDTVYNGGGFDGVAGVLTAFGAIKLLKEKQFIPKKNIAIICFASEESARFGVSTIGSKAISGELEkEKIANIK 150
73541064  159 DADGVTLAEALAASSL---PGNgelaalqaAAVDPATLLGFVEVHIEQGPVLLNKDLPLGVVTQIAGSSRFQVRIEGQAS 235
222102817 159 GPNDEPLREAIDRIGGnvsQLS---------SARRDDIFSYLEIHIEQGPVLEAKHIPIGVVTAIAGIGRVKVRFEGIAG 229
241207313 155 VSDGGDLAEGIAQVGG---RPYv------lMQQNRPDIAGFLELHIEQGPVLEAEKEDIGIVTAISGITRIEITVEGRAD 225
209551930 155 ISDGRDLAEGIAEVGG---EPGv------lAQQKRPDLAGFLELHIEQGPVLEAEREDIGIVTAIAGITRIEITVEGRAD 225
116250136 155 VSDGRDLAEGIAQVGG---RPDv------lMQQNRPDIAGFLELHIEQGPVLEAEKEDVGIVTAISGITRVEITVEGRAD 225
52081740  162 DRDGVSIEQAMKDCGFgkrRYR---------RPFRRDVKCFIELHIEQGSILEESGRQIGIVTDIVGQRRFTVMVKGESN 232
52787127  162 DRDGVSIEQAMKDCGFg--KRRy-------RRPFRRDVKCFIELHIEQGSILEESGRQIGIVTDIVGQRRFTVMVKGESN 232
56965498  156 DASGISLGEAMRANGFg--QGHy-------QAPRRTDIDCFIELHIEQGQVLEHSGNKIGIAKAIVGQRRFTVTVEGAAN 226
28210637  153 SKKGKTLKEIFGKKGYs------------lNPKKISNIKQYLELHIEQGKVLEEYRVRVGVVSDIAAPRRFNIYIQGEAE 220
23100741  151 DSEGITIKEAVEQFGV---DWEtm----dsAELPADELEQFLELHIEQGKVLEDQGLDIGIVNGIARPVRLQVKATGMAN 223
73541064  236 HAGTTPMGMRRDAAAGAAEMILLVESRCSA-VP-AL---VGTAGQLQVPDGSSNVIPAACTFSMDIRAGEDDIREAAIAD 310
222102817 230 HAGTSPMDMRADAALAMARFALAVRDAACAmQG-KGh-fTATIGVLTIEPGGANVVPGASEAIVDIRAEDDGMMDSFIEA 307
241207313 226 HAGTTPMDRRADALVAASQLVLDIRNAAAElAK-TPghfAATVGEFRIEPNAANVVPSKVVLLIDGRAEIRADMEAFCRW 304
209551930 226 HAGTTPMDRRADALVAAAQLVLDIRNAAAElAK-TPghfAATVGEFRIEPNAANVVPSKVVLLIDGRAEIRADMEAFCRW 304
116250136 226 HAGTTPMDRRADALVAAAQLVLDIRNAAAElAK-SPghfAATVGEFRIEPNAANVVPSKVVLLIDGRAEIRADMEAFCRW 304
52081740  233 HAGTTPMNARKDAVAVSALCISYLTNKAKAaYP-LL---TATVGRIEAKPNVPNVISGEAVFSLDLRHHHDAVLDRYCDD 308
52787127  233 HAGTTPMNARKDAVAVSALCISYLTNKAKAaYP-LL---TATVGRIEAKPNVPNVISGEAVFSLDLRHHHDAVLDRYCDD 308
56965498  227 HAGTTPMHMRKDAMELASRLITRLVDKARKiDE-AF---VATVGQIEAFPNTANVIPGKVSFSLDIRHHSTNMLDRYCEE 302
28210637  221 HSGATPMNMRYDALCAASEVILSIEKIGKKeAMkKS---VATVGVLNNSPNVLNVIPGEVKLGVDIRGIDKNSLNSMEEE 297
23100741  224 HTGTTPMNYRKDALVAIAPLINYVENEAIKiNErKSgtlVATVSVARVLPNAMNMIPGEIELGIDIRSTNDQLKNEMSEL 303
73541064  311 IVAGIQQIAArrGLSAQVDRVKP-VFNAPCARWLMDQFSAVLRKRGLAAFELPSGAGHDAMMMQRITDVAMLFVRCgNGG 389
222102817 308 LEGLANKAATdeKCQVALFERLSkTRAVACDSSLRVVLESAASDLNLPTLSLASGAGHDAAFMAQVTKSAMIFVPS-RDG 386
241207313 305 LDGHVEKLAAayGVTIKTPNRVSdNQPTPGDAGLLSTLEAACERVGAKHRRMASGAGHDTAWIAKVAPAAMIFVPC-RGG 383
209551930 305 LDGHVEKLATayGVTIRTPNRVSdNMPTPGDAGLLSTLEAACERVGAKHRRMASGAGHDTAWIAKVAPAAMIFVPC-REG 383
116250136 305 LDGHVEKLAGayGVTIKTPNRVSdNQPTPADPGLLSMLEAACERVGAKHRRMASGAGHDTAWIAKVAPAAMIFVPC-REG 383
52081740  309 IFAYFTELAGewNVQITVEQTTD-AKPVRMDRDLIQLSKQSAEDLDVSYQEMVSGAGHDAQVFGPHCPTSLLFVPS-RKG 386
52787127  309 IFAYFTELAGewNVQITVEQTTD-AKPVRMDRDLIQLSKQSAEDLDVSYQEMVSGAGHDAQVFGPHCPTSLLFVPS-RKG 386
56965498  303 METFFHEQEQasQLGISVDQWAD-VAPVAMDADLTALAFQSAQKTGLPVQYMYSGAGHDTQIFGSCCPTALLFVPS-KGG 380
28210637  298 IREVSENISKkrNVEIFIEKTSE-LLPVKMSQYMQERLAECCKKTKISYKILPSGAGHDAMVFPKICDTALIFIPC-SKG 375
23100741  304 INKYCGKITEdkKIEVTVNKIVD-DASVNLDKLMQGKLYKLSESMGLRTICMDSGAGHDVMNMASKWPCGLIFIPS-KHG 381
73541064  390 ISHNPLESITAEDAQLAAEVFVDFLRHF---QAQG 421
222102817 387 KSHTPDEWTDNEAIALAADVLVRALVHL---DSNT 418
241207313 384 RSHSADEWAENDDIALGAAVLFEAVREMdtsLNQE 418
209551930 384 RSHSGDEWAENDDIALGAAVLFEAVREMdkdLTRE 418
116250136 384 RSHSADEWADNDDITLGTAVLFEAVREMdtsLNQE 418
52081740  387 ISHSPEEWTKPADLAAGVELLTHVLYRLaye---- 417
52787127  387 ISHSPEEWTKPADLAAGVELLTHVLYRL-----AY 416
56965498  381 ISHSPLEFTADEDLEAGVSALAALLYKLay----- 410
28210637  376 ISHNKNEFTSLESILDGTKVMYEYLKGEiyk---- 406
23100741  382 ISHHPEEYTKTADLYKGTSLIARYLEQEa------ 410
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