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Pyridoxine 5'-phosphate (PNP) oxidase-like and flavin reductase-like proteins The PNPOx-like superfamily is composed of pyridoxine 5'-phosphate (PNP) oxidases and other flavin mononucleotide (FMN) binding proteins, which catalyze FMN-mediated redox reactions. Flavin reductases catalyze the reduction of FMN or FAD using NAD(P)H as a cofactor. They are part of a two-component enzyme system, composed of a smaller component (flavin reductase) and a larger component (an oxidase), which uses the reduced flavin to hydroxylate substrates.
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Jiyao W et al.(2023). "The conserved domain database in 2023.",