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Items: 3

1.

Defining the regulon of a CzcRS-like two-component system in Burkholderia cenocepacia K56-2

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Burkholderia cenocepacia
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing
Platform:
GPL19185
11 Samples
Download data
Series
Accession:
GSE61337
ID:
200061337
2.

Defining the role of a CzcRS-like two-component system in Burkholderia cenocepacia K56-2 (RNA-Seq)

(Submitter supplied) BACKGROUND: We identified that a putative CzcRS-like two-component system (TCS) in Burkholderia cenocepacia K56-2 is required for heavy metal resistance and virulence. To investigate this TCS further, we applied RNA-seq to determine the transcriptional response of wildtype and CzcRS-deficient B. cenocepacia to subinhibitory concetrations of zinc. METHODS. Wildtype B. cenocepacia K56-2 was cultured in LB broth with and without 1.5 mM zinc chloride. more...
Organism:
Burkholderia cenocepacia
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19185
9 Samples
Download data: TAB, TXT
Series
Accession:
GSE61336
ID:
200061336
3.

Defining the regulon of a CzcRS-like two-component system in Burkholderia cenocepacia K56-2 (ChIP-Seq)

(Submitter supplied) BACKGROUND: We identified that a putative CzcRS-like two-component system (TCS) in Burkholderia cenocepacia K56-2 is required for heavy metal resistance and virulence. In an attempt to identify genes directly regulated by the CzcR response regulator, we performed ChIP-seq analysis to identify genomic regions bound by CzcR. METHODS. Sequence encoding a FLAG octapeptide (Sigma-Aldrich) was introduced to the 3’ end of the czcR gene at its native chromosomal position in wild-type B. more...
Organism:
Burkholderia cenocepacia
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL19185
2 Samples
Download data: TXT
Series
Accession:
GSE61334
ID:
200061334
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Supplemental Content

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