GPL22923[RGSE] - GEO DataSets

Select item 2001534971.

RNA degradation analysis reveals ribosome dynamics in complex microbiome samples

(Submitter supplied) The microbiome has revealed itself as a key player in health and disease. To better understand its role, in addition to microbial diversity, it is important to understand species-specific activity and gene expression. While metatranscriptomics investigates mRNA abundance2, it does not inform about faster post-transcriptional regulation3. Although prokaryotic translation is a common target for antibiotics, a direct measurement of microbiome ribosome dynamics remains inaccessible. more...

Organism:: Segatella copri; Alistipes finegoldii; Hoylesella timonensis; compost metagenome; Escherichia coli; Synechocystis sp. PCC 6803; Staphylococcus aureus; Bacillus amyloliquefaciens; Lactiplantibacillus plantarum; Cryptococcus neoformans; Caulobacter vibrioides; Enterococcus faecalis; Bacillus subtilis; Limosilactobacillus reuteri; Limosilactobacillus fermentum; human feces metagenome; Listeria monocytogenes; Saccharomyces cerevisiae; Salmonella enterica; Parabacteroides merdae

Type:: Other

17 related Platforms
199 Samples

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Series

Accession:: GSE153497

ID:: 200153497

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Select item 2001848242.

Comparison of wild-type Synechocystis sp. PCC 6803 with strains overexpressing wild-type or 5’-sensing-deficient RNase E

(Submitter supplied) We compared transcriptomic changes, 5'-triphosphorylated (TSS) and 5'-monophosphorylated (PSS) RNA ends of different strains of the cyanobacterium Synechocystis sp. PCC6803. Comparison encompassed wild-type Synechocystis (WT), a strain overexpressing RNase E and RNase HII (rne(WT)) and a strain overexpressing 5’-sensing-deficient RNase E and RNase HII (rne(5p)). Analysis of changing 5'-monophosphorylated ends revealed 5’ sensing depedent processing sites on a transcriptome-wide level.

Organism:: Synechocystis sp. PCC 6803

Type:: Expression profiling by high throughput sequencing

Platform:: GPL22923
8 Samples

Download data: CSV, GFF

Series

Accession:: GSE184824

ID:: 200184824

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Select item 2001803163.

Analysis of transcriptomic changes with a special focus on processing sites in Synechocystis sp. PCC 6803 thermo-sensitive RNase E mutants before and after a 1 h heat shock

(Submitter supplied) We compared transcriptomic changes, 5'-triphosphorylated (TSS) and 5'-monophosphorylated (PSS) RNA ends of a thermo-sensitive and a wild-typic RNase E mutant strain of the cyanobacterium Synechocystis sp. PCC6803 (rne(Ts) and rne(WT)) before and after a heat shock. Analysis of changing 5'-monophosphorylated ends revealed RNase E depedent processing sites on a transcriptome-wide level.

Organism:: Synechocystis sp. PCC 6803

Type:: Expression profiling by high throughput sequencing

Platform:: GPL22923
12 Samples

Download data: CSV, GFF

Series

Accession:: GSE180316

ID:: 200180316

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Select item 2001151354.

Active site of cyanobacterial RNA polymerase compensates for the absence of proofreading factors

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Synechocystis sp. PCC 6803; Escherichia coli K-12

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL22923 GPL24020
6 Samples

Download data: TXT

Series

Accession:: GSE115135

ID:: 200115135

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Select item 2001151345.

Active site of cyanobacterial RNA polymerase compensates for the absence of proofreading factors [Synechoscystis sp]

(Submitter supplied) We found that cyanobacterial RNA polymerase possesses very efficient intrinsic proofreading ability. This ability allows model species of cyanobacteria, Synechocystis sp PCC 6803 to keep in vivo level of transcriptional mistakes close to that of E.coli.