Similar studies for GEO DataSets (Select 200158637) - GEO DataSets

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Items: 4

Select item 2001586371.

Spacer prioritization in CRISPR-Cas9 immunity is enabled by the leader RNA

(Submitter supplied) RIP-seq analysis to identify SpyCas9 and LrhCas9 bound RNAs using co-immunoprecipitation and sequencing.

Organism:: Escherichia coli; Lacticaseibacillus rhamnosus

Type:: Other

Platforms:: GPL30159 GPL21222
12 Samples

Download data: WIG

Series

Accession:: GSE158637

ID:: 200158637

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2001123852.

Deciphering the regulon of the alternative extracytoplasmic function (ECF) sigma factor DvdS and its dependence on the regulatory proteins CarD and CarG

(Submitter supplied) This study addresses the key role of the extracytoplasmic function (ECF) sigma factor DdvS in the Gram-negative bacterium Myxococcus xanthus. It allows us to determine its regulon and it shows that the expression of ddvS and its regulón depends on the global regulatory complex CarD-CarG.

Organism:: Myxococcus xanthus

Type:: Expression profiling by array

Platform:: GPL24768
8 Samples

Download data: TXT

Series

Accession:: GSE112385

ID:: 200112385

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001799153.

A target expression threshold dictates invader defense and autoimmunity by CRISPR-Cas13

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Escherichia coli str. K-12 substr. MG1655

Type:: Other; Expression profiling by high throughput sequencing

Platforms:: GPL26592 GPL21117
8 Samples

Download data

Series

Accession:: GSE179915

ID:: 200179915

PubMed Full text in PMC Similar studies

Select item 2001799144.

A target expression threshold dictates invader defense and autoimmunity by CRISPR-Cas13 [RNA-seq]

(Submitter supplied) The study investigates how varying target expression levels influences self-targeting and defense using Cas13a. We see how immunity is activated only over a target transcription threshold, which is variable between targets. A gRNA library targeting transcripts from the whole coding genome of E. coli MG1655 confirms the importance of the transcription threshold in determining immunity and shows that most of the cellular transcripts do not induce cytotoxicity.