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bsh choloylglycine hydrolase [ Lactobacillus acidophilus La-14 ]

Gene ID: 56942691, updated on 29-Sep-2023

Summary

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Gene symbol
bsh
Gene description
choloylglycine hydrolase
Locus tag
LA14_RS05455
Gene type
protein coding
Organism
Lactobacillus acidophilus La-14 (strain: La-14, culture-collection: ATCC:SD-5212)
Lineage
Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae; Lactobacillus
Old locus tag
LA14_1092
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Genomic context

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Sequence:
NC_021181.2 (1058274..1059251)

NC_021181.2Genomic Context describing neighboring genes Neighboring gene low temperature requirement protein A Neighboring gene replication-associated recombination protein A Neighboring gene L,D-transpeptidase Neighboring gene 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_021181.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Bile salt hydrolases: Structure and function, substrate preference, and inhibitor development. Dong Z, et al. Protein Sci, 2018 Oct. PMID 30098054, Free PMC Article
  2. Contribution of three bile-associated loci, bsh, pva, and btlB, to gastrointestinal persistence and bile tolerance of Listeria monocytogenes. Begley M, et al. Infect Immun, 2005 Feb. PMID 15664931, Free PMC Article
  3. Cloning of the bile salt hydrolase (bsh) gene from Enterococcus faecium FAIR-E 345 and chromosomal location of bsh genes in food enterococci. Wijaya A, et al. J Food Prot, 2004 Dec. PMID 15633685
  4. Listeria monocytogenes bile salt hydrolase is a PrfA-regulated virulence factor involved in the intestinal and hepatic phases of listeriosis. Dussurget O, et al. Mol Microbiol, 2002 Aug. PMID 12180927
  5. Complete Genome Sequence of Probiotic Strain Lactobacillus acidophilus La-14. Stahl B, et al. Genome Announc, 2013 Jun 20. PMID 23788546, Free PMC Article

GeneRIFs: Gene References Into Functions

General protein information

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Preferred Names
choloylglycine hydrolase
WP_003547395.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_021181.2 Reference assembly

    Range
    1058274..1059251
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_003547395.1 choloylglycine hydrolase [Lactobacillus acidophilus]

    See identical proteins and their annotated locations for WP_003547395.1

    UniProtKB/TrEMBL
    B9V407, B9V409, G1U9U7, Q5FK51
    Conserved Domains (1) summary
    cd00542
    Location:2 → 300
    Ntn_PVA; Penicillin V acylase (PVA), also known as conjugated bile salt acid hydrolase (CBAH), catalyzes the hydrolysis of penicillin V to yield 6-amino penicillanic acid (6-APA), an important key intermediate of semisynthetic penicillins. PVA has an N-terminal ...
Nucleotide Protein
Heading Accession and Version