Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Intrinsic-Fluorescence Titration from Article 10.1002/cbic.201402673: "Structure-based design of potent small-molecule binders to the S-component of the ECF transporter for thiamine."
Assay data:5 Active, 5 Activity ≤ 1 µM, 5 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Binding affinity to wild-type Lactococcus lactis MG1363 N-terminal His8-tagged ThiT expressed in Lactococcus lactis NZ9000 by isothermal calorimetric titration method
Assay data:2 Active, 4 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Binding affinity to Lactococcus lactis MG1363 N-terminal His8-tagged ThiT His125Ala mutant expressed in Lactococcus lactis NZ9000 by isothermal calorimetric titration method
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Binding affinity to Lactococcus lactis MG1363 N-terminal His8-tagged ThiT His125Asn mutant expressed in Lactococcus lactis NZ9000 by isothermal calorimetric titration method
Binding affinity to Lactococcus lactis MG1363 N-terminal His8-tagged ThiT Glu84Ala mutant expressed in Lactococcus lactis NZ9000 by isothermal calorimetric titration method
Assay data:1 Active, 1 Tested
Binding affinity to Lactococcus lactis MG1363 N-terminal His8-tagged ThiT Glu84Gln mutant expressed in Lactococcus lactis NZ9000 by isothermal calorimetric titration method
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Binding affinity to Lactococcus lactis MG1363 N-terminal His8-tagged ThiT Glu84Asp mutant expressed in Lactococcus lactis NZ9000 by isothermal calorimetric titration method
Binding affinity to Lactococcus lactis MG1363 N-terminal His8-tagged ThiT Trp34Ala mutant expressed in Lactococcus lactis NZ9000 incubated for 5 secs measured over 20 secs by fluorescence spectrophotometric method
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
Binding affinity to wild-type Lactococcus lactis MG1363 N-terminal His8-tagged ThiT expressed in Lactococcus lactis NZ9000 incubated for 10 secs measured over 15 secs by fluorescence spectrophotometric method
Assay data:13 Active, 2 Activity ≤ 1 nM, 13 Activity ≤ 1 µM, 13 Tested
Binding affinity to Lactococcus lactis MG1363 N-terminal His8-tagged ThiT His125Phe mutant expressed in Lactococcus lactis NZ9000 by isothermal calorimetric titration method
Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB
Assay data:3916 Active, 206 Activity ≤ 1 nM, 1830 Activity ≤ 1 µM, 3916 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on