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Inhibition of Campylobacter jejuni PgIC expressed in Escherichia coli by affinity chromatography
Assay data:1 Tested
Summary
Antibacterial activity against Campylobacter jejuni assessed as resistant isolates by disk diffusion method
Assay data:15 Tested
SummaryPubMed Citation
Inhibition of Campylobacter jejuni DHDPS using using ASA as a substrate in presence of NADPH by DHDPS-DHDPR coupled assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Inhibition of Campylobacter jejuni phosphoglycosyl transferase Pg1D
Reversible inhibition of Campylobacter jejuni dihydrodipicolinate synthase
SummaryCompounds, ActiveCompounds, activity ≤ 1 µM
Inhibition of Campylobacter jejuni dihydrodipicolinate synthase
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
Competitive inhibition of Campylobacter jejuni NCTC 11168 PglD acetyltransferase expressed in Escherichia coli BL-21(DE3) strain (Stratagene) assessed as release of CoASH preincubated for 30 mins followed by addition of UDP-4-aminosugar and 5 fold excess AcCoA as substrate by Ellman's method
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of Campylobacter jejuni NCTC 11168 PglD acetyltransferase expressed in Escherichia coli BL-21(DE3) strain (Stratagene) assessed as release of CoASH preincubated for 30 mins followed by addition of 300 uM AcCoA and 500 uM UDP-4-aminosugar as substrate by Ellman's method
Assay data:39 Active, 20 Activity ≤ 1 µM, 39 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of Campylobacter jejuni NCTC 11168 PglD acetyltransferase expressed in Escherichia coli BL-21(DE3) strain (Stratagene) assessed as release of CoASH preincubated for 45 mins followed by addition of AcCoA and UDP-4-aminosugar measured after 30 mins by fragment-based high-throughput screening analysis
Assay data:1 Active, 1 Activity ≤ 1 µM, 4 Tested
Competitive inhibition of Campylobacter jejuni NCTC 11168 PglD acetyltransferase expressed in Escherichia coli BL-21(DE3) strain (Stratagene) assessed as release of CoASH preincubated for 30 mins followed by addition of UDP-4-aminosugar and 2 fold excess AcCoA as substrate by Ellman's method
Antimicrobial activity against Campylobacter jejuni
Assay data:7 Active, 3 Activity ≤ 1 µM, 15 Tested
Inhibition of PFOR Campylobacter jejuni
SummaryPubMed CitationRelated BioAssays by Target
Competitive inhibition of Campylobacter jejuni NCTC 11168 PglD acetyltransferase expressed in Escherichia coli BL-21(DE3) strain (Stratagene) assessed as release of CoASH preincubated for 30 mins followed by addition of AcCoA and higher levels of UDP-4-aminosugar as substrate by Ellman's method
Inactivation of CmeABC efflux pump in Campylobacter jejuni 25-19 assessed as change in clarithromycin MIC by agar dilution method
Inactivation of CmeABC efflux pump in Campylobacter jejuni 25-19 assessed as change in erythromycin MIC by agar dilution method
Assay data:2 Tested
Ratio of MIC for Campylobacter jejuni 001B-40 carrying A2075G mutation in 23S rRNA to MIC for Campylobacter jejuni 001B-40 cmeB::kanamycin-resistant mutant
Ratio of MIC for Campylobacter jejuni 001B-22 carrying A2075G mutation in 23S rRNA to MIC for Campylobacter jejuni 001B-22 cmeB::kanamycin-resistant mutant
Activity of PFOR in Campylobacter jejuni at anaerobic condition
Antimicrobial activity against Campylobacter jejuni harboring mutation in cmeB by agar dilution method relative to wild type Campylobacter jejuni
Antimicrobial activity against Campylobacter jejuni ATCC 33291 incubated at 37 degC for 24 hrs by broth macrodilution method
Assay data:3 Tested
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