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Enzyme Inhibition Assay from Article 10.1021/jm801224t: "Structure-activity relationships of orotidine-5'-monophosphate decarboxylase inhibitors as anticancer agents."
Assay data:4 Active, 4 Activity ≤ 1 µM, 8 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Enzyme Inhibition Assay from Article 10.1021/jm7010673: "Structure-activity relationships of C6-uridine derivatives targeting plasmodia orotidine monophosphate decarboxylase."
Assay data:3 Active, 2 Activity ≤ 1 µM, 5 Tested
Inhibition of N-terminal His9-tagged Methanocaldococcus jannaschii DSM 2661 AglH incubated for 2 hrs using UDP-GlcN-Cg-FITC and alpha-dihydroundecap-renyl phosphate by reversed-phase HPLC analysis
Assay data:3 Active, 2 Activity ≤ 1 µM, 11 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Inhibition of Methanobacterium thermoautotrophicum ODCase
Assay data:1 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of Methanobacterium thermoautotrophicum beta-carbonic anhydrase preincubated for 15 mins by stopped flow CO2 hydration assay
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of Methanobacterium thermoautotrophicum beta-carbonic anhydrase
SummaryPubMed Citation
Inhibition of Methanobacterium thermoautotrophicum ODCase by isothermal titration calorimetry
Assay data:3 Tested
Inhibition of Methanobacterium thermoautotrophicum 5'-monophosphate decarboxylase by VP-ITC microcalorimeter
Irreversible inhibition of Methanobacterium thermoautotrophicum 5'-monophosphate decarboxylase
Assay data:1 Active, 1 Activity ≤ 1 µM, 3 Tested
Inhibition of Methanothermobacter thermautotrophicus carbonic anhydrase after 15 mins by stopped flow CO2 hydration assay
Inhibition of Methanothermobacter thermautotrophicus uridine 5'-monophosphate synthase after overnight incubation at room temperature by VP-ITC microcalorimetry
Assay data:1 Active, 1 Tested
Activation of archaea Methanobacterium thermoautotrophicum recombinant carbonic anhydrase by stopped flow CO2 hydration method
Assay data:19 Tested
Inhibition of Methanobacterium thermoautotrophicum carbonic anhydrase by stopped flow CO2 hydration method
Activation of Methanothermobacter thermautotrophicus recombinant Cab by stopped-flow CO2 hydrase method
Assay data:18 Tested
Activation of Methanobacterium thermoautotrophicum beta-class CA by stopped-flow CO2 hydrase assay
Irreversible inhibition of Methanobacterium thermoautotrophicum ODCase
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
Reversible inhibition of Methanobacterium thermoautotrophicum ODCase
Assay data:3 Active, 3 Activity ≤ 1 µM, 8 Tested
Inhibition of Methanobacterium thermoautotrophicum Cab at 20 degC by CO2 hydration method
Assay data:5 Tested
Inhibition of Methanobacterium thermoautotrophium ODCase by time dependent assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Assay data:2 Active, 2 Activity ≤ 1 µM, 5 Tested
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