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Coupled Nucleotide Exchange Assay from US Patent US20240059703: "HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE"
Assay data:506 Active, 473 Activity ≤ 1 µM, 513 Tested
SummaryRelated BioAssays by Target
TBD from US Patent US20240059694: "COMPOUND CONTAINING 1,3-BENZODIOXOL STRUCTURE AND PREPARATION METHOD AND USE THEREOF"
Assay data:28 Active, 30 Activity ≤ 1 µM, 30 Tested
Potentiator Assay from US Patent US20240058315: "Pyridine and Pyrazine derivative for the Treatment of CF, COPD, and Bronchiectasis"
Assay data:13 Active, 13 Activity ≤ 1 µM, 13 Tested
Measuring Antiviral Effect of Compounds from US Patent US11905306: "Substituted phenyl ethynyl pyridine carboxamides as potent inhibitors of SARS virus"
Assay data:70 Active, 38 Activity ≤ 1 µM, 80 Tested
Biochemical AlphaScreen assay from US Patent US11905273: "Inhibitors for the B-catenin/B-cell lymphoma 9 (BCL9) protein-protein interaction"
Assay data:4 Active, 5 Tested
KRAS::SOS1 AlphaScreen Binding Assay from US Patent US20240051956: "SOS1 INHIBITORS AND USES THEREOF"
Assay data:85 Active, 87 Activity ≤ 1 µM, 87 Tested
IC50 Determination from US Patent US20240043470: "MACROCYCLIC COMPOUNDS AS PROTEASOME INHIBITORS"
Assay data:80 Active, 18 Activity ≤ 1 µM, 160 Tested
SOS-Catalyzed Nucleotide Exchange Assay from US Patent US20240043448: "Small Molecule Inhibitors of KRAS G12C Mutant"
Assay data:93 Active, 7 Activity ≤ 1 nM, 83 Activity ≤ 1 µM, 93 Tested
MCF-7 Cell Growth Study from US Patent US20240043442: "SELECTIVE ESTROGEN RECEPTOR DEGRADERS AND USES THEREOF"
Assay data:50 Active, 30 Activity ≤ 1 nM, 50 Activity ≤ 1 µM, 50 Tested
Antiviral Assay from US Patent US20240043417: "COMPOUNDS FOR THE TREATMENT OF SARS"
Assay data:1 Active, 19 Tested
SARS-CoV-2 3CLpro Enzyme Assay from US Patent US20240043417: "COMPOUNDS FOR THE TREATMENT OF SARS"
Assay data:11 Active, 23 Tested
Biological Assays gainst IRAK1 from US Patent US20240043405: "POTENT AND SELECTIVE IRREVERSIBLE INHIBITORS OF IRAK1"
Assay data:21 Active, 20 Activity ≤ 1 µM, 21 Tested
HPK1 Kinase Binding Assay from US Patent US11891388: "Pyrazolopyridine compounds and uses thereof"
Assay data:76 Active, 66 Activity ≤ 1 µM, 76 Tested
IC50 Assay from US Patent US11890356: "HDAC6 inhibitors and imaging agents"
Assay data:18 Active, 16 Activity ≤ 1 µM, 18 Tested
Inhibitory Action on Binding of BRD4 Protein and Ligand from US Patent US11890288: "Sulfonamide or sulfinamide compound having effect of inducing BRD4 protein degradation and pharmaceutical use thereof"
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
TBD from US Patent US20240034743: "TRICYCLIC COMPOUNDS AS EGFR INHIBITORS"
Assay data:135 Active, 118 Activity ≤ 1 nM, 137 Activity ≤ 1 µM, 137 Tested
Assay data:133 Active, 31 Activity ≤ 1 nM, 137 Activity ≤ 1 µM, 137 Tested
CDK4/Cyclin D1 CHEF Assay from US Patent US20240034731: "AZA-QUINAZOLINE COMPOUNDS AND METHODS OF USE"
Assay data:79 Active, 76 Activity ≤ 1 µM, 81 Tested
CDK4/Cyclin D1 Mobility Shift Assay (MSA) from US Patent US20240034731: "AZA-QUINAZOLINE COMPOUNDS AND METHODS OF USE"
CDK2/Cyclin E1 Full length ADP-Glo Kinase Assay from US Patent US20240034731: "AZA-QUINAZOLINE COMPOUNDS AND METHODS OF USE"
Assay data:95 Active, 92 Activity ≤ 1 µM, 97 Tested
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