Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Enzyme Inhibition Assay from US Patent US8785499: "Targeting NAD biosynthesis in bacterial pathogens"
Assay data:8 Tested
SummaryRelated BioAssays by Target
NaMNAT HPLC Enzyme Assay from Article 10.1021/cc9000357: "SAR studies for a new class of antibacterial NAD biosynthesis inhibitors."
Assay data:2 Active, 77 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Enzymatic Inhibition Assay from Article 10.1016/j.chembiol.2009.07.006: "Targeting NAD biosynthesis in bacterial pathogens: Structure-based development of inhibitors of nicotinate mononucleotide adenylyltransferase NadD."
Assay data:2 Active, 8 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB
Assay data:3916 Active, 206 Activity ≤ 1 nM, 1830 Activity ≤ 1 µM, 3916 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Experimentally measured binding affinity data (IC50) for protein-ligand complexes derived from PDB
Assay data:4302 Active, 250 Activity ≤ 1 nM, 2931 Activity ≤ 1 µM, 4302 Tested
Inhibition of Bacillus anthracis nicotinate-nucleotide adenosyltransferase up to 100 uM preincubated for 5 mins before addition of substrate by malachite green reagent method
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of Bacillus anthracis nicotinate-nucleotide adenosyltransferase preincubated for 5 mins before addition of substrate by malachite green reagent method
Assay data:1 Active, 10 Tested
Inhibition of Bacillus anthracis nicotinate-nucleotide adenosyltransferase preincubated for 5 mins before addition of ATP substrate by malachite green reagent method
Assay data:1 Active, 2 Tested
Inhibition of Bacillus anthracis nicotinate-nucleotide adenosyltransferase preincubated for 5 mins before addition of NaMN substrate by malachite green reagent method
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on