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In Vitro Enzyme Activity Assay from Article 10.1021/bi030031h: "Thermodynamic characterization of the binding of nucleotides to glycyl-tRNA synthetase."
Assay data:2 Active, 2 Activity ≤ 1 µM, 6 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Validation qHTS for agonist of cAMP-regulated guanine nucleotide exchange factor 4 (EPAC2)
Assay data:41 Active, 124 Activity ≤ 1 µM, 15613 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Validation qHTS for antagonist of cAMP-regulated guanine nucleotide exchange factor 4 (EPAC2)
Assay data:265 Active, 171 Activity ≤ 1 µM, 15637 Tested
Validation qHTS for agonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1)
Assay data:160 Active, 22 Activity ≤ 1 µM, 15634 Tested
Validation qHTS for antagonist of cAMP-regulated guanine nucleotide exchange factor 3 (EPAC1)
Assay data:115 Active, 91 Activity ≤ 1 µM, 15634 Tested
P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen
Assay data:1430 Active, 11 Activity ≤ 1 nM, 385 Activity ≤ 1 µM, 10968 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen
Assay data:1153 Active, 10968 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same Project
Human pregnane X receptor (PXR) activation by small molecules, qHTS assay
Assay data:229 Active, 16 Activity ≤ 1 µM, 2454 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
CYP3A4 induction through human pregnane X receptor (PXR) by small molecules, qHTS assay
Assay data:172 Active, 50 Activity ≤ 1 µM, 2454 Tested
Rat pregnane X receptor (rPXR) activation by small molecules, qHTS assay
Assay data:107 Active, 27 Activity ≤ 1 µM, 2454 Tested
Drug repurposing screens with cells derived from glioblastoma tumor samples
Assay data:1237 Active, 3 Activity ≤ 1 nM, 360 Activity ≤ 1 µM, 3733 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µM
Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening
Assay data:2353 Active, 12805 Tested
SummaryCompounds, ActivePubMed Citation
Toxoplasma gondii HTS in the absence of IFN-y
Assay data:614 Active, 6425 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Target
Toxoplasma gondii inhibition HTS in the presence of IFN-y
Assay data:2597 Active, 69085 Tested
GENE-TOX mutagenicity studies
Assay data:1995 Active, 3214 Tested
SummaryCompounds, Active
qHTS assay to identify small molecule inhibitors of chordoma cells - UCH-2
Assay data:49 Active, 17 Activity ≤ 1 µM, 2815 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Depositor
qHTS assay to identify small molecule inhibitors of chordoma cells - UCH-1
Assay data:89 Active, 14 Activity ≤ 1 nM, 175 Activity ≤ 1 µM, 2815 Tested
qHTS assay to identify small molecule phospholipidosis (PLD) inducers
Assay data:37 Active, 24 Activity ≤ 1 µM, 3730 Tested
uHTS identification of small molecule modulators of Rev-erb Alpha.
Assay data:2957 Active, 372399 Tested
Antioxidant activity in rat PC12 cells assessed as inhibition of Fe2+-induced reactive oxygen species formation after 1 hr by DCFH-DA dye-based fluorometric analysis
Assay data:3 Active, 2 Activity ≤ 1 µM, 10 Tested
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