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Items: 5

Select item 71365001.

The Rise of the CRISPR/Cpf1 System for Efficient Genome Editing in Plants

Anshu Alok, Dulam Sandhya, Phanikanth Jogam, Vandasue Rodrigues, Kaushal K. Bhati, Himanshu Sharma, Jitendra Kumar

Front Plant Sci. 2020; 11: 264. Published online 2020 Mar 31. doi: 10.3389/fpls.2020.00264

PMCID:: PMC7136500

Abstract Article PDF–1.8M

Select item 70939782.

A Cas12a ortholog with stringent PAM recognition followed by low off-target editing rates for genome editing

Peng Chen, Jin Zhou, Yibin Wan, Huan Liu, Yongzheng Li, Zhaoxin Liu, Hongjian Wang, Jun Lei, Kai Zhao, Yiliang Zhang, Yan Wang, Xinghua Zhang, Lei Yin

Genome Biol. 2020; 21: 78. Published online 2020 Mar 25. doi: 10.1186/s13059-020-01989-2

PMCID:: PMC7093978

Abstract Article PDF–3.1M

Select item 82113573.

Next Generation Precision Medicine: CRISPR-mediated Genome Editing for the Treatment of Neurodegenerative Disorders

Sudhanshu P. Raikwar, Nidhi Kikkeri, Ragha Sakuru, Daniyal Saeed, Haris Zahoor, Keerthivaas Premkumar, Shireen Mentor, Ramasamy Thangavel, Iuliia Dubova, Mohammad Ejaz Ahmed, Govindhasamy P. Selvakumar, Duraisamy Kempuraj, Smita Zaheer, Shankar S. Iyer, Asgar Zaheer

J Neuroimmune Pharmacol. Author manuscript; available in PMC 2021 Jun 17.

Published in final edited form as: J Neuroimmune Pharmacol. 2019 Dec; 14(4): 608–641. Published online 2019 Apr 23. doi: 10.1007/s11481-019-09849-y

PMCID:: PMC8211357

Abstract Article PDF–1.2M

Select item 55624074.

Engineering CRISPR-Cpf1 crRNAs and mRNAs to maximize genome editing efficiency

Bin Li, Weiyu Zhao, Xiao Luo, Xinfu Zhang, Chenglong Li, Chunxi Zeng, Yizhou Dong

Nat Biomed Eng. Author manuscript; available in PMC 2017 Nov 10.

Published in final edited form as: Nat Biomed Eng. 2017 May; 1(5): 0066. Published online 2017 May 10. doi: 10.1038/s41551-017-0066

PMCID:: PMC5562407

Abstract Article PDF–2.7M

Select item 46382205.

Cpf1 is a single RNA-guided endonuclease of a Class 2 CRISPR-Cas system

Bernd Zetsche, Jonathan S. Gootenberg, Omar O. Abudayyeh, Ian M. Slaymaker, Kira S. Makarova, Patrick Essletzbichler, Sara Volz, Julia Joung, John van der Oost, Aviv Regev, Eugene V. Koonin, Feng Zhang

Cell. Author manuscript; available in PMC 2016 Oct 22.

Published in final edited form as: Cell. 2015 Oct 22; 163(3): 759–771. Published online 2015 Sep 25. doi: 10.1016/j.cell.2015.09.038