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Select item 110599891.

Dual targeting of glutamine and serine metabolism in acute myeloid leukemia

Kanwal M. Hameed, Dominique R. Bollino, Amol C. Shetty, Brandon Carter-Cooper, Rena G. Lapidus, Ashkan Emadi

Front Oncol. 2024; 14: 1326754. Published online 2024 Apr 16. doi: 10.3389/fonc.2024.1326754

PMCID:: PMC11059989

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Select item 109914892.

Xylanolytic Bacillus species for xylooligosaccharides production: a critical review

Rozina Rashid, Muhammad Sohail

Bioresour Bioprocess. 2021 Dec; 8(1): 16. Published online 2021 Feb 17. doi: 10.1186/s40643-021-00369-3

PMCID:: PMC10991489

Article PDF–1.1M

Select item 109317653.

Genetic Loci of Plant Pathogenic Dickeya solani IPO 2222 Expressed in Contact with Weed-Host Bittersweet Nightshade (Solanum dulcamara L.) Plants

Robert Czajkowski, Dorota M. Krzyżanowska, Daryna Sokolova, Łukasz Rąbalski, Maciej Kosiński, Sylwia Jafra, Aleksandra Królicka

Int J Mol Sci. 2024 Mar; 25(5): 2794. Published online 2024 Feb 28. doi: 10.3390/ijms25052794

PMCID:: PMC10931765

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Select item 108814284.

Targeting myeloma metabolism: How abnormal metabolism contributes to multiple myeloma progression and resistance to proteasome inhibitors

Xiang Zhou, Rui He, Wei-Xin Hu, Saiqun Luo, Jingping Hu

Neoplasia. 2024 Apr; 50: 100974. Published online 2024 Feb 16. doi: 10.1016/j.neo.2024.100974

PMCID:: PMC10881428

Article PDF–1.3M

Select item 108523535.

Elucidation of the Active Form and Reaction Mechanism in Human Asparaginase Type III Using Multiscale Simulations

Milorad Andjelkovic, Kirill Zinovjev, Carlos Alberto Ramos-Guzmán, Jose Javier Ruiz- Pernía, Iñaki Tuñón

J Chem Inf Model. 2023 Sep 11; 63(17): 5676–5688. Published online 2023 Aug 28. doi: 10.1021/acs.jcim.3c00900

PMCID:: PMC10852353

Article PDF–7.6M

Select item 108096696.

l-Asparaginase from Solanum lycopersicum as a Nutraceutical for Acute Lymphoblastic Leukemia

Sarina P. Khabade, Divijendra Natha Reddy Sirigiri, Anshu Beulah Ram

ACS Omega. 2024 Jan 23; 9(3): 3616–3624. Published online 2024 Jan 5. doi: 10.1021/acsomega.3c07633

PMCID:: PMC10809669

Article PDF–3.6M

Select item 105345867.

l-Asparaginase Type II from Fusarium proliferatum: Heterologous Expression and In Silico Analysis

Samuel Leite Cardoso, Paula Monteiro Souza, Kelly Rodrigues, Isabella de Souza Mota, Edivaldo Ferreira Filho, Léia Cecilia de Lima Fávaro, Felipe Saldanha-Araujo, Mauricio Homem-de-Mello, Adalberto Pessoa, Dâmaris Silveira, Yris Maria Fonseca-Bazzo, Pérola Oliveira Magalhães

Pharmaceutics. 2023 Sep; 15(9): 2352. Published online 2023 Sep 20. doi: 10.3390/pharmaceutics15092352

PMCID:: PMC10534586

Article PDF–3.6M

Select item 107662108.

A Review of Acute Lymphocytic Leukemia (ALL) in the Pediatric Population: Evaluating Current Trends and Changes in Guidelines in the Past Decade

Queen L Ekpa, Prince C Akahara, Alexis M Anderson, Omowunmi O Adekoya, Olamide O Ajayi, Peace O Alabi, Okelue E Okobi, Oluwadamilola Jaiyeola, Medara S Ekanem

Cureus. 2023 Dec; 15(12): e49930. Published online 2023 Dec 4. doi: 10.7759/cureus.49930

PMCID:: PMC10766210

Article PDF–594K

Select item 107198559.

Soft rot pathogen Dickeya dadantii 3937 produces tailocins resembling the tails of Peduovirus P2

Marcin Borowicz, Dorota M. Krzyżanowska, Magdalena Narajczyk, Marta Sobolewska, Magdalena Rajewska, Paulina Czaplewska, Katarzyna Węgrzyn, Robert Czajkowski

Front Microbiol. 2023; 14: 1307349. Published online 2023 Nov 30. doi: 10.3389/fmicb.2023.1307349

PMCID:: PMC10719855

Article PDF–1.9M

Select item 1068522610.

Allergic Reactions to E. coli Asparaginase are Associated with Decreased Asparaginase Activity in an Indonesian Pediatric Population with ALL

Nur Melani Sari, Afiat Berbudi, Susi Susanah, Lelani Reniarti, Eddy Supriyadi, Gertjan J L Kaspers, Randal K Buddington, Scott Howard, Ponpon Idjradinata

Asian Pac J Cancer Prev. 2023; 24(8): 2773–2780. doi: 10.31557/APJCP.2023.24.8.2773

PMCID:: PMC10685226

Article PDF–504K

Select item 1068399211.

Characterization and applications of glutaminase free L-asparaginase from indigenous Bacillus halotolerans ASN9

Ifrah Shafqat, Shaheen Shahzad, Azra Yasmin, Muhammad Tausif Chaudhry, Safia Ahmed, Aneela Javed, Imran Afzal, Monaza Bibi

PLoS One. 2023; 18(11): e0288620. Published online 2023 Nov 28. doi: 10.1371/journal.pone.0288620

PMCID:: PMC10683992

Article PDF–1.2M

Select item 1067654612.

Expression and Biological Evaluation of an Engineered Recombinant L-asparaginase Designed by In Silico Method Based on Sequence of the Enzyme from Escherichia coli

Mahrokh Dastmalchi, Mahdiyeh Alizadeh, Omid Jamshidi-Kandjan, Hassan Rezazadeh, Maryam Hamzeh-Mivehroud, Mohammad M Farajollahi, Siavoush Dastmalchi

Adv Pharm Bull. 2023 Nov; 13(4): 827–836. Published online 2023 Jun 12. doi: 10.34172/apb.2023.085

PMCID:: PMC10676546

Article PDF–1020K

Select item 1065177013.

Recombinant Erwinia asparaginase (JZP458) in acute lymphoblastic leukemia: results from the phase 2/3 AALL1931 study

Luke Maese, Mignon L. Loh, Mi Rim Choi, Tong Lin, Etsuko Aoki, Michelle Zanette, Shirali Agarwal, Robert Iannone, Jeffrey A. Silverman, Lewis B. Silverman, Elizabeth A. Raetz, Rachel E. Rau

Blood. 2023 Feb 16; 141(7): 704–712. Published online 2022 Sep 17. doi: 10.1182/blood.2022016923

PMCID:: PMC10651770

Article

Select item 1060704414.

Engineering and Expression Strategies for Optimization of L-Asparaginase Development and Production

Anastasiya N. Shishparenok, Yulia A. Gladilina, Dmitry D. Zhdanov

Int J Mol Sci. 2023 Oct; 24(20): 15220. Published online 2023 Oct 16. doi: 10.3390/ijms242015220

PMCID:: PMC10607044

Article PDF–4.1M

Select item 1054020515.

Immunogenic epitope scanning in bacteriolytic enzymes Pal and Cpl-1 and engineering Pal to escape antibody responses

Marek Adam Harhala, Katarzyna Gembara, Izabela Rybicka, Zuzanna Maria Kaźmierczak, Paulina Miernikiewicz, Joanna Marta Majewska, Wiktoria Budziar, Anna Nasulewicz-Goldeman, Daniel C. Nelson, Barbara Owczarek, Krystyna Dąbrowska

Front Immunol. 2023; 14: 1075774. Published online 2023 Sep 15. doi: 10.3389/fimmu.2023.1075774

PMCID:: PMC10540205

Article PDF–4.4M

Select item 1053127216.

Arginine Is a Novel Drug Target for Arginine Decarboxylase in Human Colorectal Cancer Cells

Xinlei Wei, Ho-Yin Chow, Hiu-Chi Chong, Siu-Lun Leung, Mei-Ki Ho, Man-Yuen Lee, Yun-Chung Leung

Int J Mol Sci. 2023 Sep; 24(18): 13741. Published online 2023 Sep 6. doi: 10.3390/ijms241813741

PMCID:: PMC10531272

Article PDF–2.5M

Select item 1049976817.

Optimization and characterization of antileukemic l-asparaginase produced by Fusarium solani endophyte

Sarah Osama, Moshera M. El-Sherei, Dalia A. Al-Mahdy, Mokhtar Bishr, Osama Salama, Marwa M. Raafat

AMB Express. 2023; 13: 96. Published online 2023 Sep 13. doi: 10.1186/s13568-023-01602-2

PMCID:: PMC10499768

Article PDF–1.5M

Select item 1039945518.

Insight into metabolic sensors of nitrosative stress protection in Phytophthora infestans

Joanna Gajewska, Jolanta Floryszak-Wieczorek, Arkadiusz Kosmala, Dawid Perlikowski, Marek Żywicki, Ewa Sobieszczuk-Nowicka, Howard S. Judelson, Magdalena Arasimowicz-Jelonek

Front Plant Sci. 2023; 14: 1148222. Published online 2023 Jul 20. doi: 10.3389/fpls.2023.1148222