Protein Family Models for Gene (Select 45816447) - Protein Family Models

Select item 1915181.

Gene:: iscS

Date:: 2021-02-10

Family Accession:: NBR010983
Method:: BlastRule

Select item 1421582.

This HMM represents IscS, one of several cysteine desulfurases from a larger protein family designated (misleadingly, in this case) class V aminotransferases. IscS is one of at least 6 enzymes characteristic of the IscSUA-hscAB-fsx system of iron-sulfur cluster assembly. Scoring almost as well as proteobacterial sequences included in the model are mitochondrial cysteine desulfurases, apparently from an analogous system in eukaryotes. The sulfur, taken from cysteine, may be used in other systems as well, such as tRNA base modification and biosynthesis of other cofactors.

GO Terms:

Biological Process:: iron-sulfur cluster assembly (GO:0016226)

Molecular Function:: cysteine desulfurase activity (GO:0031071)

Date:: 2021-04-27

Family Accession:: TIGR02006.1
Method:: HMM

Select item 555833.

IscS subfamily cysteine desulfurase

IscS subfamily cysteine desulfurase is a pyridoxal-5'-phoshate dependent enzyme that catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine

GO Terms:

Molecular Function:: cysteine desulfurase activity (GO:0031071)

Molecular Function:: pyridoxal phosphate binding (GO:0030170)

Molecular Function:: 2 iron, 2 sulfur cluster binding (GO:0051537)

Biological Process:: [2Fe-2S] cluster assembly (GO:0044571)

Date:: 2023-03-21

Family Accession:: 10014534
Method:: Sparcle

Select item 447754.

new record, indexing in progress

Family Accession:

Select item 439825.

new record, indexing in progress

Family Accession:

Select item 376756.

IscS subfamily cysteine desulfurase

GO Terms:

Molecular Function:: pyridoxal phosphate binding (GO:0030170)

Molecular Function:: cysteine desulfurase activity (GO:0031071)

Biological Process:: [2Fe-2S] cluster assembly (GO:0044571)

Date:: 2021-08-12

Family Accession:: NF010611.0
Method:: HMM

Select item 354607.

new record, indexing in progress

Family Accession:

Select item 349468.

new record, indexing in progress

Family Accession:

Select item 294039.

IscS subfamily cysteine desulfurase

GO Terms:

Molecular Function:: catalytic activity (GO:0003824)

Date:: 2021-11-04

Family Accession:: NF002806.0
Method:: HMM

Select item 2801310.

new record, indexing in progress

Family Accession:

Select item 2769411.

new record, indexing in progress

Family Accession:

Protein Family Models

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