TrlF (WP_011144772.1) from Photorhabdus laumondii was described as an 875-amino acid protein encoded in a small genomic island operon next to TrlG, whose mutation and loss of function restores an ability to grow at 36 degrees C. A related protein, Spaf_1101, although outside the scope of the model, has similar N-terminal and C-terminal domains and nucleotide-binding GxxGxGLS (P-loop) motif. Spaf_1101 is described as occurring at one end of a transposon, and the high frequency of pseudogenes among its close homologs suggests a role in mobile element function.
- Date:
- 2024-03-08