Protein Family Models for Protein (Select 2719506153) - Protein Family Models

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Items: 2

Select item 3901211.

glycosyltransferase family 9 protein

Members of this family belong to glycosyltransferase family 9 [1]. Lipopolysaccharide is a major component of the outer leaflet of the outer membrane in Gram-negative bacteria. It is composed of three domains; lipid A, Core oligosaccharide and the O-antigen. All of these enzymes transfer heptose to the lipopolysaccharide core. [1]. 9334165. A classification of nucleotide-diphospho-sugar. glycosyltransferases based on amino acid sequence similarities. Campbell JA, Davies GJ, Bulone V, Henrissat B;. Biochem J 1997;326:929-939.. [2]. 9446588. Enzymatic synthesis of lipopolysaccharide in Escherichia coli.. Purification and properties of heptosyltransferase I.. Kadrmas JL, Raetz CR;. J Biol Chem 1998;273:2799-2807. (from Pfam)

GO Terms:

Molecular Function:: glycosyltransferase activity (GO:0016757)

Date:: 2024-04-03

Family Accession:: NF013257.4
Method:: HMM

Select item 1422902.

lipopolysaccharide heptosyltransferase I

This family consists of examples of ADP-heptose:LPS heptosyltransferase I, an enzyme of LPS inner core region biosynthesis. LPS, composed of lipid A, a core region, and O antigen, is found in the outer membrane of Gram-negative bacteria.