The Genome Sequence of the Halobacterium salinarum Type Strain Is Closely Related to That of Laboratory Strains NRC-1 and R1

Friedhelm Pfeiffer; Anita Marchfelder; Bianca Habermann; Mike L Dyall-Smith

doi:10.1128/MRA.00429-19

The Genome Sequence of the Halobacterium salinarum Type Strain Is Closely Related to That of Laboratory Strains NRC-1 and R1

Microbiol Resour Announc. 2019 Jul 11;8(28):e00429-19. doi: 10.1128/MRA.00429-19.

Authors

Friedhelm Pfeiffer¹, Anita Marchfelder², Bianca Habermann^{3

4}, Mike L Dyall-Smith^{3

5}

Affiliations

¹ Computational Biology Group, Max Planck Institute of Biochemistry, Martinsried, Germany fpf@biochem.mpg.de.
² Biology II, Ulm University, Ulm, Germany.
³ Computational Biology Group, Max Planck Institute of Biochemistry, Martinsried, Germany.
⁴ CNRS, IBDM UMR 7288, Computational Biology Group, Aix Marseille Université, Marseille, France.
⁵ Veterinary Biosciences, Faculty of Veterinary and Agricultural Sciences, University of Melbourne, Parkville, Australia.

Abstract

High-coverage long-read sequencing of the Halobacterium salinarum type strain (91-R6) revealed a 2.17-Mb chromosome and two large plasmids (148 and 102 kb). Population heterogeneity and long repeats were observed. Strain 91-R6 and laboratory strain R1 showed 99.63% sequence identity in common chromosomal regions and only 38 strain-specific segments. This information resolves the previously uncertain relationship between type and laboratory strains.