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Adaptation of Propionibacterium freudenreichii to the colon environment

(Submitter supplied) Mechanisms allowing P. freudenreichii adaptation to digestive stresses have been only studied in vitro so far. Our aim was therefore to study P. freudenreichii metabolic adaptation to intra-colonic conditions in situ. We maintained a pure culture of P. freudenreichii CIRM-BIA1, contained in a dialysis bag, within the colon of vigilant piglets during 24 hours. A transcriptomic analysis identified the metabolic pathways induced by this environment, in comparison with control propionibacteria maintained in spent culture medium.
Organism:
Propionibacterium freudenreichii
Type:
Expression profiling by array
Platform:
GPL17609
8 Samples
Download data: TXT
Series
Accession:
GSE50089
ID:
200050089

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