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| Status |
Public on Dec 11, 2013 |
| Title |
Adaptation of Propionibacterium freudenreichii to the colon environment |
| Organism |
Propionibacterium freudenreichii |
| Experiment type |
Expression profiling by array
|
| Summary |
Mechanisms allowing P. freudenreichii adaptation to digestive stresses have been only studied in vitro so far. Our aim was therefore to study P. freudenreichii metabolic adaptation to intra-colonic conditions in situ.
We maintained a pure culture of P. freudenreichii CIRM-BIA1, contained in a dialysis bag, within the colon of vigilant piglets during 24 hours. A transcriptomic analysis identified the metabolic pathways induced by this environment, in comparison with control propionibacteria maintained in spent culture medium.
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| Overall design |
12 cutures in a dialysis bag in the colon of piglets during 24H compared to 12 cultures propionibacteria maintained in spent culture medium
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| Contributor(s) |
Saraoui T, Parayre S, Guernec G, Loux V, Montfort J, Lecam A, Boudry G, Jan G, Falentin H |
| Citation(s) |
24365073 |
| Submission date |
Aug 22, 2013 |
| Last update date |
Apr 14, 2014 |
| Contact name |
Hélène Falentin |
| E-mail(s) |
helene.falentin@rennes.inra.fr
|
| Organization name |
INRA
|
| Department |
Microbiologie
|
| Lab |
UMR STLO
|
| Street address |
65 rue de St Brieuc
|
| City |
Rennes |
| ZIP/Postal code |
35042 |
| Country |
France |
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| Platforms (1) |
| GPL17609 |
Agilent-034169 Propionibacterium freudenreichii Custom Microarray (Probe Name version) |
|
| Samples (8)
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| Relations |
| BioProject |
PRJNA215993 |
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