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Links from GEO DataSets

Items: 10

1.

Burkholderia cepacia complex and cystic fibrosis (CF) patients

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Burkholderia cenocepacia J2315; Burkholderia multivorans; Burkholderia multivorans ATCC 17616
Type:
Expression profiling by array; Other
Platform:
GPL13356
10 Samples
Download data: CEL
Series
Accession:
GSE30568
ID:
200030568
2.

Hybridization of Burkholderia multivorans D2095 and D2214 genomic DNA

(Submitter supplied) Burkholderia cepacia complex (Bcc) comprises opportunistic bacteria infecting hosts such as cystic fibrosis (CF) patients. Bcc long-term infection of CF patient airways has been associated with emergence of phenotypic variation. Here we studied two Burkholderia multivorans clonal isolates (D2095 and D2214) displaying different morphotypes from a chronically infected CF patient in order to evaluate traits development during lung infection. more...
Organism:
Burkholderia cenocepacia J2315; Burkholderia multivorans; Burkholderia multivorans ATCC 17616
Type:
Other
Platform:
GPL13356
4 Samples
Download data: CEL, TXT
Series
Accession:
GSE30402
ID:
200030402
3.

Expression data from Burkholderia multivorans cystic fibrosis clinical isolates

(Submitter supplied) Burkholderia cepacia complex (Bcc) comprises opportunistic bacteria infecting hosts such as cystic fibrosis (CF) patients. Bcc long-term infection of CF patient airways has been associated with emergence of phenotypic variation. Here we studied two Burkholderia multivorans clonal isolates (D2095 and D2214) displaying different morphotypes from a chronically infected CF patient in order to evaluate traits development during lung infection.
Organism:
Burkholderia cenocepacia J2315; Burkholderia multivorans; Burkholderia multivorans ATCC 17616
Type:
Expression profiling by array
Platform:
GPL13356
6 Samples
Download data: CEL
Series
Accession:
GSE28306
ID:
200028306
4.

Expression data from Burkholderia multivorans mucoid and nonmucoid isolates

(Submitter supplied) Burkholderia multivorans comprises opportunistic bacteria infecting hosts such as cystic fibrosis (CF) patients. Bcc long-term infection of CF patient airways has been associated with emergence of phenotypic variation including the mucoid-to-nonmucoid colony morphotype. Here we studied three Burkholderia multivorans clonal isolates (mucoid D2095 (BM11L), and nonmucoid D2214G and D2214P) and a laboratory nonmucoid variant (BM11L-nmv1) obtained under prolonged stationary phase. more...
Organism:
Burkholderia multivorans; Burkholderia multivorans ATCC 17616; Burkholderia cenocepacia J2315
Type:
Expression profiling by array
Platform:
GPL13356
12 Samples
Download data: CEL
Series
Accession:
GSE111467
ID:
200111467
5.

Expression data from Burkholderia multivorans ATCC 17616 wild-type and Bmul_2557 (ldhR) gene deletion mutant

(Submitter supplied) Within this work we identified and characterized gene Bmul_2557 (ldhR) of B. multivorans ATCC 17616, a bacterial species associated with chronic respiratory infections in cystic fibrosis patients. LdhR belongs to the LysR-type family of transcriptional regulators and its deletion from the B. multivorans genome affected considerably the formation of planktonic cellular aggregates and surface-attached biofilms.
Organism:
Burkholderia cenocepacia J2315; Burkholderia multivorans; Burkholderia multivorans ATCC 17616
Type:
Expression profiling by array
Platform:
GPL13356
9 Samples
Download data: CEL
Series
Accession:
GSE97006
ID:
200097006
6.

Overexpression of a histone-like nucleoid structuring protein in Burkholderia multivorans affects several traits dependent on the cell envelope

(Submitter supplied) Burkholderia cepacia complex bacteria comprise opportunistic pathogens causing chronic respiratory infections in cystic fibrosis (CF) patients. These microorganisms produce exopolysaccharides which are considered virulence determinants. Here, we report the isolation of an evolved nonmucoid variant (17616nmv) after the ancestor, Burkholderia multivorans ATCC 17616, was subjected to prolonged stationary phase. more...
Organism:
Burkholderia multivorans; Burkholderia cenocepacia J2315; Burkholderia multivorans ATCC 17616
Type:
Expression profiling by array
Platform:
GPL13356
6 Samples
Download data: CEL
Series
Accession:
GSE162693
ID:
200162693
7.

Expression data from Burkholderia cepacia IST408 bceE and bceF mutants

(Submitter supplied) The bacterial tyrosine (BY) kinase family comprises the major group of bacterial enzymes endowed with tyrosine kinase activity. We have previously shown that the BceF protein from Burkholderia cepacia IST408 belongs to this BY kinase family and is involved in the biosynthesis of the exopolysaccharide cepacian. However, little is known about the extent of regulation in the cell by this kinase protein. more...
Organism:
Burkholderia cepacia; Burkholderia multivorans ATCC 17616; Burkholderia cenocepacia J2315
Type:
Expression profiling by array
Platform:
GPL15600
10 Samples
Download data: CEL
Series
Accession:
GSE38183
ID:
200038183
8.

An investigation of Burkholderia cepacia complex methylomes via SMRT sequencing and mutant analysis

(Submitter supplied) While nucleotide sequences determine an organism’s proteins, methylation of the nucleotides themselves can confer additional properties. In bacteria, differences in methylation can be used to identify incoming DNA, for example from bacteriophages. Restriction enzymes detect the methylation status at specific sequence motifs, and cleave improperly methylated, foreign DNA. Furthermore, methylation of key genetic regions can influence gene expression and hence phenotype. more...
Organism:
Burkholderia cenocepacia H111
Type:
Expression profiling by high throughput sequencing
Platform:
GPL23128
4 Samples
Download data: TXT
Series
Accession:
GSE147038
ID:
200147038
9.

Identification of potential therapeutic targets for Burkholderia cenocepacia by comparative transcriptomics

(Submitter supplied) [1] Transcription profiling of one Burkholderia cenocepacia clinical isolate, J2315, versus a soil isolate, HI2424, in conditions mimicking CF sputum [2] Transcription profiling of Burkholderia cenocepacia isolates J2315 and HI2424 in media mimicking CF sputum or the soil environment
Organism:
Burkholderia cenocepacia
Type:
Expression profiling by array
Platform:
GPL8475
8 Samples
Download data: TXT
Series
Accession:
GSE15817
ID:
200015817
10.

Mapping the Burkholderia cenocepacia niche response via high-throughput sequencing

(Submitter supplied) Transcriptional profiling of RNA-seq data from two Burkholderia species grown under conditions mimicking the cystic fibrosis lung and the soil environment
Organism:
Burkholderia cenocepacia
Type:
Expression profiling by high throughput sequencing
Platform:
GPL9702
8 Samples
Download data: TXT, XLS
Series
Accession:
GSE19115
ID:
200019115
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