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Links from GEO DataSets

Items: 13

1.

Expression data from Burkholderia cepacia IST408 bceE and bceF mutants

(Submitter supplied) The bacterial tyrosine (BY) kinase family comprises the major group of bacterial enzymes endowed with tyrosine kinase activity. We have previously shown that the BceF protein from Burkholderia cepacia IST408 belongs to this BY kinase family and is involved in the biosynthesis of the exopolysaccharide cepacian. However, little is known about the extent of regulation in the cell by this kinase protein. more...
Organism:
Burkholderia cepacia; Burkholderia multivorans ATCC 17616; Burkholderia cenocepacia J2315
Type:
Expression profiling by array
Platform:
GPL15600
10 Samples
Download data: CEL
Series
Accession:
GSE38183
ID:
200038183
2.

Expression data from Burkholderia multivorans mucoid and nonmucoid isolates

(Submitter supplied) Burkholderia multivorans comprises opportunistic bacteria infecting hosts such as cystic fibrosis (CF) patients. Bcc long-term infection of CF patient airways has been associated with emergence of phenotypic variation including the mucoid-to-nonmucoid colony morphotype. Here we studied three Burkholderia multivorans clonal isolates (mucoid D2095 (BM11L), and nonmucoid D2214G and D2214P) and a laboratory nonmucoid variant (BM11L-nmv1) obtained under prolonged stationary phase. more...
Organism:
Burkholderia multivorans; Burkholderia multivorans ATCC 17616; Burkholderia cenocepacia J2315
Type:
Expression profiling by array
Platform:
GPL13356
12 Samples
Download data: CEL
Series
Accession:
GSE111467
ID:
200111467
3.

Overexpression of a histone-like nucleoid structuring protein in Burkholderia multivorans affects several traits dependent on the cell envelope

(Submitter supplied) Burkholderia cepacia complex bacteria comprise opportunistic pathogens causing chronic respiratory infections in cystic fibrosis (CF) patients. These microorganisms produce exopolysaccharides which are considered virulence determinants. Here, we report the isolation of an evolved nonmucoid variant (17616nmv) after the ancestor, Burkholderia multivorans ATCC 17616, was subjected to prolonged stationary phase. more...
Organism:
Burkholderia multivorans; Burkholderia cenocepacia J2315; Burkholderia multivorans ATCC 17616
Type:
Expression profiling by array
Platform:
GPL13356
6 Samples
Download data: CEL
Series
Accession:
GSE162693
ID:
200162693
4.

Burkholderia cepacia complex and cystic fibrosis (CF) patients

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Burkholderia cenocepacia J2315; Burkholderia multivorans; Burkholderia multivorans ATCC 17616
Type:
Expression profiling by array; Other
Platform:
GPL13356
10 Samples
Download data: CEL
Series
Accession:
GSE30568
ID:
200030568
5.

Hybridization of Burkholderia multivorans D2095 and D2214 genomic DNA

(Submitter supplied) Burkholderia cepacia complex (Bcc) comprises opportunistic bacteria infecting hosts such as cystic fibrosis (CF) patients. Bcc long-term infection of CF patient airways has been associated with emergence of phenotypic variation. Here we studied two Burkholderia multivorans clonal isolates (D2095 and D2214) displaying different morphotypes from a chronically infected CF patient in order to evaluate traits development during lung infection. more...
Organism:
Burkholderia cenocepacia J2315; Burkholderia multivorans; Burkholderia multivorans ATCC 17616
Type:
Other
Platform:
GPL13356
4 Samples
Download data: CEL, TXT
Series
Accession:
GSE30402
ID:
200030402
6.

Expression data from Burkholderia multivorans cystic fibrosis clinical isolates

(Submitter supplied) Burkholderia cepacia complex (Bcc) comprises opportunistic bacteria infecting hosts such as cystic fibrosis (CF) patients. Bcc long-term infection of CF patient airways has been associated with emergence of phenotypic variation. Here we studied two Burkholderia multivorans clonal isolates (D2095 and D2214) displaying different morphotypes from a chronically infected CF patient in order to evaluate traits development during lung infection.
Organism:
Burkholderia cenocepacia J2315; Burkholderia multivorans; Burkholderia multivorans ATCC 17616
Type:
Expression profiling by array
Platform:
GPL13356
6 Samples
Download data: CEL
Series
Accession:
GSE28306
ID:
200028306
7.

BolA is a transcriptional switch that turns off motility and turns on biofilm development

(Submitter supplied) Bacteria are extremely versatile organisms which rapidly adapt to changing environments. When Escherichia coli cells switch from planktonic growth to biofilm, flagellum formation is turned off, and the production of fimbriae and extracellular polysaccharides is switched on. Here we show that BolA protein is a new bacterial transcription factor which modulates the switch from planktonic to sessile lifestyle. more...
Organism:
Escherichia coli str. K-12 substr. MG1655; Escherichia coli
Type:
Expression profiling by array
Platform:
GPL3154
12 Samples
Download data: CEL
Series
Accession:
GSE58509
ID:
200058509
8.

P. aeruginosa PAO1 PA2663 mutant vs. wild type strain

(Submitter supplied) P. aeruginosa PAO1 wild type and PA2663 mutant strains expression in biofilm cells relative to P. aeruginosa PAO1 wild type strain expression in biofilm cells. All samples cultured in LB with glass wool Keywords: Biofilm
Organism:
Pseudomonas aeruginosa
Type:
Expression profiling by array
Platform:
GPL84
2 Samples
Download data: CEL
Series
Accession:
GSE9255
ID:
200009255
9.

Expression data from Burkholderia multivorans ATCC 17616 wild-type and Bmul_2557 (ldhR) gene deletion mutant

(Submitter supplied) Within this work we identified and characterized gene Bmul_2557 (ldhR) of B. multivorans ATCC 17616, a bacterial species associated with chronic respiratory infections in cystic fibrosis patients. LdhR belongs to the LysR-type family of transcriptional regulators and its deletion from the B. multivorans genome affected considerably the formation of planktonic cellular aggregates and surface-attached biofilms.
Organism:
Burkholderia cenocepacia J2315; Burkholderia multivorans; Burkholderia multivorans ATCC 17616
Type:
Expression profiling by array
Platform:
GPL13356
9 Samples
Download data: CEL
Series
Accession:
GSE97006
ID:
200097006
10.

Gene expression analysis of rel knockout and dcpA knockout strains of Mycobacterium smegmatis MC2 155

(Submitter supplied) The experiment was carried out to study the effect of loss of (p)ppGpp or cyclic di-GMP on the gene expression pattern of Mycobacterium smegmatis MC2 155 strains. The cells were cultured in MB7H9 broth containing 0.2% glycerol and 0.05% Tween 80. The transcriptome analysis was performed using GeneSpring GX12 software. Fold changes were calculated with respect to the median expression of wild type replicates. more...
Organism:
Mycolicibacterium smegmatis MC2 155
Type:
Expression profiling by array
Platform:
GPL20299
6 Samples
Download data: TXT
Series
Accession:
GSE69681
ID:
200069681
11.

High intracellular c-di-GMP levels antagonize quorum sensing and virulence gene expression in Burkholderia cenocepacia H111

(Submitter supplied) In this study, we have analysed the transcriptional profile of B. cenocepacia H111 upon artificially altering the global cellular c-di-GMP levels. A total of 111 genes was found to be differentially expressed, of which 96 genes were down-regulated when c-di-GMP concentrations were increased. The BDSF, AHL and c-di-GMP regulons overlap for the regulation of 24 genes. Intriguingly, at a high intracellular c-di-GMP level expression of the AHL synthase cepI was found to be more than 10-fold down-regulated. more...
Organism:
Burkholderia cenocepacia H111
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16128
8 Samples
Download data: TXT
Series
Accession:
GSE92442
ID:
200092442
12.

Francisella Expression Microarray Analysis

(Submitter supplied) Francisella tularensis is a Gram-negative bacterium that is highly virulent in humans, causing the disease tularemia. F. novicida is closely related to F. tularensis and exhibits high virulence in mice, but is avirulent in healthy humans. A F. novicida-specific gene cluster (FTN0451-FTN0456) encodes two proteins with diguanylate cyclase (DGC) and phosphodiesterase (PDE) domains that modulate synthesis and degradation of cyclic di-GMP (cdGMP). more...
Organism:
Francisella; Francisella tularensis subsp. novicida
Type:
Expression profiling by array
Platform:
GPL15848
4 Samples
Download data: CALLS, PAIR
Series
Accession:
GSE39647
ID:
200039647
13.

Cyclic diguanylate regulates virulence factor genes via multiple riboswitches in Clostridium difficile

(Submitter supplied) The c-di-GMP regulon in C. difficile
Organism:
Clostridioides difficile
Type:
Expression profiling by high throughput sequencing
Platform:
GPL22510
8 Samples
Download data: XLSX
Series
Accession:
GSE120198
ID:
200120198
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