GEO DataSets

(Submitter supplied) Pathogenic microorganisms have evolved various strategies to sense and respond to stress in order to establish infection and ensure survival within the host's complex environment. Hypoxia, a metabolic stress factor encountered by aerobic microorganisms during rapid growth, remains poorly understood in terms of pathogen adaptation. Streptococcus suis, a zoonotic pathogen causing meningitis and sepsis, exhibits remarkable adaptability to anaerobic conditions. more...

Organism:

Streptococcus suis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL28677

6 Samples

Download data: TXT

(Submitter supplied) RNA sequencing analysis of the transcriptome of the wild type (WT) strain and ΔadcR mutant. The data revealed that genes encoding the Zn acquisition systems were negatively regulated by AdcR.

Organism:

Streptococcus suis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL30562

6 Samples

Download data: XLS

(Submitter supplied) The transcriptome of the wild type strain and ΔtroR of Streptococcus suis was compared by RNA sequencing analysis. The data revealed that some genes, such as the troABCD operon, were significantly differentially expressed in the ΔtroR mutant.

Organism:

Streptococcus suis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL28813

6 Samples

Download data: TXT

(Submitter supplied) We explored the transcriptome change of Streptococcus suis in the presence of manganese by RNA sequencing. The data revealed that the genes in the troABCD operon were significantly downregulated in response to manganese.

Organism:

Streptococcus suis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL28813

6 Samples

Download data: XLSX

(Submitter supplied) We explored the transcriptome change of Streptococcus suis in the presence of ferrous iron and cobalt by RNA sequencing. The data revealed that expression of a lot of genes was altered to respond to ferrous iron and cobalt toxicity. Moreover, most of the genes differentially expressed in response to cobalt are the same as those in response to ferrous iron.

Organism:

Streptococcus suis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL28813

9 Samples

Download data: XLSX

(Submitter supplied) During infection in the air pouches, S. suis encounters changing environments and host factors. It is important for S. suis to modulate the gene expression in response to stimulants. Using DNA microarray analysis, we compared the transcriptome of S. suis obtained from the air pouches with that from working cultures.

Organism:

Streptococcus suis; Streptococcus suis SC84

Type:

Expression profiling by array

Platform:

GPL18421

8 Samples

Download data: TXT

(Submitter supplied) To investigate the effect of CodY mutation on the gene expression in Streptococcus suis serotype 2 SC19 strain, we have employed whole genome microarray expression profiling as a discovery platform to identify genes regulated by CodY mutation. DNA microarray analysis was performed using an Agilent custom-designed oligonucleotide microarray. Based upon the whole genome sequence of SC19 , specific 60-mer oligonucleotide probes were designed using eArray (https://earray.chem.agilent.com/earray/), to cover all annotated genes. more...

Organism:

Streptococcus suis

Type:

Expression profiling by array

Platform:

GPL20080

2 Samples

Download data: TXT

(Submitter supplied) To reveal the scope of the Spx regulation and explore the differences in the regulatory roles of SpxA1 and SpxA2, the global gene transcription profiles of the WT, ∆spxA1 and ∆spxA2 strains were determined by DNA microarray analysis performed using an Agilent custom-designed oligonucleotide microarray.

Organism:

Streptococcus suis SC84; Streptococcus suis

Type:

Expression profiling by array

Platform:

GPL18421

8 Samples

Download data: TXT