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| Status |
Public on Aug 09, 2012 |
| Title |
Mutation Mapping of 31 Streptococcus suis strains |
| Platform organism |
Streptococcus suis GZ1 |
| Sample organism |
Streptococcus suis |
| Experiment type |
Genome variation profiling by genome tiling array
|
| Summary |
Identification of Genes and Genomic Islands Correlated with High Pathogenicity through Tilling Microarray-Based Comparative Genomics in S. suis.
Streptococcus suis is an important zoonotic pathogen that can cause meningitis and sepsis in both pigs and humans. S. suis isolates have been categorized into groups of different levels of pathogenicity, with sequence type (ST) ST1 clonal complex strains having a higher degree of virulence than other STs. However, the genetic basis of the differences in pathogenicity is still poorly understood. In this study, a comprehensive genomic comparison of 31 S. suis strains from different clinical sources with the genome sequence of the high pathogenicity (HP) strain GZ1 was conducted using NimbleGen’s tilling microarray platform.
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| Overall design |
Comparative genomic analysis on the 31 S. suis strains of different serotypes and ST types through tilling arrays.
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| Contributor(s) |
Zheng H, Zheng X, Ye C, Xu J |
| Citation(s) |
21479213 |
| Submission date |
Dec 14, 2010 |
| Last update date |
Aug 10, 2012 |
| Contact name |
Xiao Zheng |
| E-mail(s) |
zhengxiao@icdc.cn
|
| Organization name |
China CDC
|
| Street address |
Liuzi five hao
|
| City |
Beijing |
| ZIP/Postal code |
102206 |
| Country |
China |
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| Platforms (1) |
| GPL11315 |
ICDC Streptococcus suis GZ1 tilling arrays (MAP01, MAP02) |
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| Samples (31)
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| Relations |
| BioProject |
PRJNA135555 |
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