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| Status |
Public on Oct 21, 2019 |
| Title |
Transcriptional profile Lactobacillus plantarum WCFS1 : Oleuropein treated cells |
| Organism |
Lactiplantibacillus plantarum |
| Experiment type |
Expression profiling by array
|
| Summary |
Whole genome transcriptional profiling was used to characterize the response of Lactobacillus plantarum WCFS1 human isolate during challenge with oleuropein. Twelve independent experiments were performed and mixed at random in groups of four for total of three RNA samples. The transcriptional profile shows that Lactobacillus plantarum WCFS1 adapts its metabolic capacity to acquire certain carbohydrates and repress the expression of genes involved in fatty acid biosyntheis. The transcriptomic datasets also revealed the downregulation of genes related to the biosynthesis of capsular polysaccharides and genes coding for ABC-type transporters. In addition, induction of oligopeptide permeases is also part of the response of Lactobacillus plantarum WCFS1 to oleuropein.
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| Overall design |
Biological triplicates: untreated cells: Control vs. Oleuropein treated cells: Experimental
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| Contributor(s) |
Reverón I, Plaza L, de las Rivas B, Muñoz R, López de Felipe F |
| Citation(s) |
31620115 |
| Submission date |
Nov 30, 2016 |
| Last update date |
Oct 23, 2019 |
| Contact name |
Felix Lopez de Felipe |
| E-mail(s) |
fxlopez@ictan.csic.es
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| Organization name |
ICTAN-CSIC
|
| Street address |
Jose Antonio Novais
|
| City |
Madrid |
| ZIP/Postal code |
28040 |
| Country |
Spain |
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| Platforms (1) |
| GPL22663 |
Agilent-026636 Lactobacillus plantarum Prueba Lp IFI 021109 |
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| Samples (3) |
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| Relations |
| BioProject |
PRJNA355586 |
