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Series GSE65278 Query DataSets for GSE65278
Status Public on Feb 28, 2015
Title Autoimmune peptide antigen reactivity in BXD2 mice with spontaneous systemic autoimmune disease Pepperchip 2.0
Platform organisms Helicobacter pylori; Escherichia coli; Klebsiella pneumoniae; Proteus mirabilis; Shigella flexneri; Yersinia enterocolitica; Haemophilus influenzae; Chlamydia trachomatis; Porphyromonas gingivalis; Staphylococcus aureus; Streptococcus pyogenes; Lactobacillus delbrueckii subsp. bulgaricus; Mycobacterium avium; Mycobacterium tuberculosis variant bovis; Mycobacterium avium subsp. paratuberculosis; Mycobacterium tuberculosis; Mycobacterium gordonae; Trypanosoma cruzi; Homo sapiens; Mus musculus; Human alphaherpesvirus 1; Human alphaherpesvirus 2; Human betaherpesvirus 5; Human betaherpesvirus 6; human gammaherpesvirus 4; Human herpesvirus 4 strain B95-8; Hepatitis C virus isolate HC-J6; Human immunodeficiency virus 1; Human T-cell leukemia virus type I; Human T-cell lymphotrophic virus type 1 (isolate MT-2); Coxsackievirus A9; Coxsackievirus B4; Human herpesvirus 4 type 2; Human adenovirus 12; Human herpesvirus 4 type 1; Coxsackievirus A20; Human endogenous retrovirus K; Human Endogenous Retrovirus IDDMK1,2-22; Torque teno virus; Chlamydia pneumoniae; Prochlorococcus marinus str. MIT 9202; Human rotavirus MP409; Coxsackievirus B4 (strain E2); Paraburkholderia fungorum; Porphyromonas gingivalis W83; Mycobacterium avium subsp. paratuberculosis K-10; Human poliovirus 3 strain Sabin; Staphylococcus aureus A9635; Betapolyomavirus macacae; Hepacivirus hominis
Sample organism Mus musculus
Experiment type Protein profiling by protein array
Summary The aim of the array was to determine the BXD2 mouse sera IgG and IgM reactivity profile to linear peptide epitopes. Pooled sera from three 6-9 month old BXD2 mice was diluted at 1:200 for IgG specific analysis or 1:1000 for IgM specific analysis and incubated on a PEPperPRINT peptide microarray platform printed with peptide autoantigens
 
Overall design In this study, pooled sera from three 6-9 month old BXD2 mice was profiled for IgG and IgM specific autoantibody reactivity to peptide auto-epitopes printed in duplicate on a PepperPrint Chip.
 
Contributor(s) Hamilton JA, Mountz JD, Hsu H
Citation(s) 25888644
Submission date Jan 26, 2015
Last update date May 30, 2015
Contact name Jennie Hamilton
Organization name University of Alabama Birmingham
Department Department of Medicine, Division of Clinical Immunology and Rheumatology
Street address 1825 University Blvd.
City Birmingham
State/province AL
ZIP/Postal code 35294
Country USA
 
Platforms (1)
GPL19701 PEPperCHIP Autoimmunity Microarray 2.0
Samples (2)
GSM1591572 pooled BXD2 sera (BXD2 IgG Profile)
GSM1591573 pooled BXD2 sera (BXD2 IgM Profile)
This SubSeries is part of SuperSeries:
GSE65290 General Approach for Tetramer Based Identification of Autoantigen Reactive B Cells: Characterization of La and snRNP Reactive B Cells in Autoimmune BXD2 Mice
Relations
BioProject PRJNA273620

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE65278_PP-2_BXD2_Raw.xlsx 1.4 Mb (ftp)(http) XLSX
Processed data included within Sample table

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