GEO DataSets

(Submitter supplied) Transcriptional profiling of probiotic Lactobacillus rhamnosus strain GG mid-exponential pH-controlled bioreactor cultures before and after exposure to bovine bile (0.2% ox gall). Keywords: bile, stress response

Organism:

Lacticaseibacillus rhamnosus; Lacticaseibacillus rhamnosus GG

Type:

Expression profiling by array

Platform:

GPL10580

12 Samples

Download data: GPR

(Submitter supplied) Transcriptional profiling of probiotic Lactobacillus rhamnosus GG during growth in industrial-type whey medium in pH-controlled bioreactor cultures at two different growth pH: 4.8 and 5.8. Keywords: growth phase, growth pH

Organism:

Lacticaseibacillus rhamnosus GG

Type:

Expression profiling by array

Platform:

GPL10580

66 Samples

Download data: GPR

(Submitter supplied) Bifidobacterium longum is one of the natural inhabitants in human gastrointestinal tract. In order to colonize and exert particular functions in the gut, it has to be tolerant to the physiological concentrations of bile salts. In this work, we used RNA-Seq transcriptomics based on the Next-Generation Sequencing to investigate the global response to bile in B. longum BBMN68, a potential probiotic strain isolated from a healthy centenarian. more...

Organism:

Bifidobacterium longum

Type:

Expression profiling by high throughput sequencing

Platform:

GPL17084

2 Samples

Download data: TXT

(Submitter supplied) The response to bile of Lactobacillus casei BL23 was investigated.

Organism:

Lacticaseibacillus casei; Lacticaseibacillus paracasei ATCC 334

Type:

Expression profiling by array

Platform:

GPL11074

6 Samples

Download data: TXT

(Submitter supplied) The response to bile of Lactobacillus casei BL23 and its derivative strain TC01 was investigated. TC01 strain carries a complete deletion of gene LCABL_02080 which encodes a two component signal transduction response regulator.

Organism:

Lacticaseibacillus paracasei ATCC 334; Lacticaseibacillus casei

Type:

Expression profiling by array

Platform:

GPL11074

12 Samples

Download data: TXT

(Submitter supplied) This study aimed to investigate the effects of oral administration of lactic acid bacteria (LAB) on gene expression in murine ileum. To evaluate the strain specific and dose effects of LAB on the gene expression of distal ileum, Lactococcus lactis C59 and Lactobacillus rhamnosus GG were administered at a dose of 1 x 107 cells (10^7), 1 x 108 (10^8) cells or 1 x 109 (10^9) cells Microarray analysis was performed using total RNA from distal ileum to detail the gene expression of 7 groups; control, C59- and GG-administered at a dose of 1 x 107 cells (10^7), 1 x 108 (10^8) cells or 1 x 109 (10^9) cells. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL1261

35 Samples

Download data: CEL

(Submitter supplied) This study aimed to investigate the effects of oral administration of lactic acid bacteria (LAB) on gene expression in murine ileum. Two LAB strains, Lactococcus lactis subsp. lactis C59 and Lactobacillus rhamnosus GG, were administered to mice for 2 weeks. Microarray analysis was performed using total RNA from upper and lower ileum to detail the gene expression of 3 groups; control, C59-administered and GG-administered. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Platform:

GPL1261

30 Samples

Download data: CEL

(Submitter supplied) Analysis of human primary macrophages after live Lactobacillus rhamnosus GG (LGG) or LC705 stimulation for 6h and 24h. The results reveal novel mechanisms for probiotics-induced activation of the healthy human innate immune system. Macrophages are phagocytic cells of the innate immune system that perform sentinel functions to initiate appropriate responses to surrounding stimuli. Macrophages that reside at mucosa encounter ingested bacteria. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL6879

18 Samples

Download data: CEL