GEO DataSets

(Submitter supplied) To reveal the scope of the stk regulation and explore the differences in the regulatory roles of SC-19 and ∆stk, the global gene transcription profiles of the WT and ∆stk strains were determined by RNA-seq analysis.

Organism:

Streptococcus suis

Type:

Expression profiling by high throughput sequencing

Platform:

GPL22539

2 Samples

Download data: TXT

(Submitter supplied) The interactions of Streptocococcus suis (S.suis) with human microvascular endothelial cells (hBMEC) are important process for S.suis passage across human blood brain barrier (BBB). S.suis has evolved precise mechanisms to alter gene expression depending on the distinct challenges posed by particular disease sites. Herein, a whole-genome DNA microarray was used to investigate the change of gene expression profile of S.suis after contact with hBMEC 3 h. more...

Organism:

Streptococcus suis 05ZYH33

Type:

Expression profiling by array

Platform:

GPL9675

4 Samples

Download data: GPR

(Submitter supplied) The interactions of Streptocococcus suis (S.suis) with human microvascular endothelial cells (hBMEC) are important process for S.suis passage across human blood brain barrier (BBB). S.suis has evolved precise mechanisms to alter gene expression depending on the distinct challenges posed by particular disease sites. Herein, a whole-genome DNA microarray was used to investigate the change of gene expression profile of S.suis after contact with hBMEC 1 h. more...

Organism:

Streptococcus suis 05ZYH33

Type:

Expression profiling by array

Platform:

GPL9675

4 Samples

Download data: GPR

(Submitter supplied) During infection in the air pouches, S. suis encounters changing environments and host factors. It is important for S. suis to modulate the gene expression in response to stimulants. Using DNA microarray analysis, we compared the transcriptome of S. suis obtained from the air pouches with that from working cultures.

Organism:

Streptococcus suis; Streptococcus suis SC84

Type:

Expression profiling by array

Platform:

GPL18421

8 Samples

Download data: TXT

(Submitter supplied) To investigate the effect of CodY mutation on the gene expression in Streptococcus suis serotype 2 SC19 strain, we have employed whole genome microarray expression profiling as a discovery platform to identify genes regulated by CodY mutation. DNA microarray analysis was performed using an Agilent custom-designed oligonucleotide microarray. Based upon the whole genome sequence of SC19 , specific 60-mer oligonucleotide probes were designed using eArray (https://earray.chem.agilent.com/earray/), to cover all annotated genes. more...

Organism:

Streptococcus suis

Type:

Expression profiling by array

Platform:

GPL20080

2 Samples

Download data: TXT

(Submitter supplied) To reveal the scope of the Spx regulation and explore the differences in the regulatory roles of SpxA1 and SpxA2, the global gene transcription profiles of the WT, ∆spxA1 and ∆spxA2 strains were determined by DNA microarray analysis performed using an Agilent custom-designed oligonucleotide microarray.

Organism:

Streptococcus suis SC84; Streptococcus suis

Type:

Expression profiling by array

Platform:

GPL18421

8 Samples

Download data: TXT

(Submitter supplied) Streptococcus suis is an important zoonotic pathogen that can cause meningitis and sepsis in both pigs and humans. In this study,we evaluated the genetic difference of 40 Streptococcus suis strains belonging to various sequence types by comparative genomic hybridization to identify genes associated with the variation in pathogenicity using NimbleGen’s tilling microarray platform. Application of Comparative Phylogenomics to Identify Genetic Differences Relating to Pathogenicity of Streptococcus suis

Organism:

Streptococcus suis

Type:

Genome variation profiling by genome tiling array

Platforms:

GPL15924 GPL15923

80 Samples

Download data: PAIR, TXT

(Submitter supplied) Streptococcus suis is an important emerging worldwide pig pathogen and zoonotic agent with rapid evolution of virulence and drug resistance. Licochalcone A, used in traditional Chinese medicine, exhibits antimicrobial, antioxidant and anti-inflammatory activities. Herein, a whole-genome DNA microarray was used to investigate the global transcriptional regulation of Streptococcus suis 05ZYH33 treated by subinhibitory concentration of licochalcone A. more...

Organism:

Streptococcus suis 05ZYH33

Type:

Expression profiling by array

Platform:

GPL9675

4 Samples

Download data: GPR

(Submitter supplied) Identification of Genes and Genomic Islands Correlated with High Pathogenicity through Tilling Microarray-Based Comparative Genomics in S. suis. Streptococcus suis is an important zoonotic pathogen that can cause meningitis and sepsis in both pigs and humans. S. suis isolates have been categorized into groups of different levels of pathogenicity, with sequence type (ST) ST1 clonal complex strains having a higher degree of virulence than other STs. more...

Organism:

Streptococcus suis; Streptococcus suis GZ1

Type:

Genome variation profiling by genome tiling array

Platform:

GPL11315

31 Samples

Download data: PAIR

(Submitter supplied) For a pathogen such as Streptococcus suis serotype 2, ecological success is determined by its ability to sense the environment and mount an appropriate adaptive transcriptional response. Thus, determining conditions for analysis of gene expression in vitro that are representative of the in vivo environment is critical for understanding the contributions of transcriptional response pathways to pathogenesis. more...

Organism:

Streptococcus suis 05ZYH33

Type:

Expression profiling by array

Platform:

GPL9675

1 Sample

Download data: GPR

(Submitter supplied) Streptococcus suis 2 Rgg-dependent transcription was analyzed.

Organism:

Streptococcus suis 05ZYH33

Type:

Expression profiling by array

Platform:

GPL10447

2 Samples

Download data: TXT

(Submitter supplied) Streptococcus suis serotype 2 (SS2) is able to cause human infections ranging from superficial wounded skin infections to severe invasive infections such as meningitis and streptococcal toxic shock-like syndrome (STSLS). During its infection cycle, SS2 must acclimatize itself to temperature shift. Herein, a whole-genome DNA microarray was used to investigate the global transcriptional regulation of an invasive SS2 strain grown to late-exponential phase at 29 or 40°C relative to 37°C. more...

Organism:

Streptococcus suis 05ZYH33

Type:

Expression profiling by array

Platform:

GPL9675

2 Samples

Download data: GPR

(Submitter supplied) Streptococcus suis serotype 2 (SS2), an important zoonotic agent, is notorious for causing contagious porcine diseases and human infection. The two outbreaks in China (in 1998 and in 2005) have caused serious economic losses in the pig industry and posed public health for its new toxin shock symptoms (TSS). However, the molecular mechanism of SS2 pathogenicity is still poorly understood. In order to get insights into pathogenecity of SS2, eighteen SS2 strains of different virulence and sources have been subjected to whole genome comparison by NimbleGen CGS arrays

Organism:

Streptococcus suis

Type:

Genome variation profiling by genome tiling array

Platforms:

GPL9120 GPL9121

36 Samples

Download data: PAIR, TXT

(Submitter supplied) According to the whole genome sequence of 05ZYH33 (NC_009442), specific oligo-nucleotide probes with an average length of 35 nt were designed to cover every putative ORF (2194 in total) in SS2 genome using Array Designer 2.0 and then synthesized onto complementary metal oxide semiconductor (CMOS) matrix utilizing in situ electrochemical synthesis technique.

Organism:

Streptococcus suis 05ZYH33

1 Series

2 Samples

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(Submitter supplied) Based on the whole-genome sequences of Streptococcus suis serotype 2 strain 05ZYH33, a total number of 2194 annotated open reading frames (ORFs) were selected after the exclusion of ORFs encoding IS protein, integrase, and transposase (The word “gene” will be used in the following part of this paper in reference to the ORF). Those highly homologous to each other at nucleotide level were also excluded. more...

Organism:

Streptococcus suis 05ZYH33

5 Series

15 Samples

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